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Showing 1993 to 2004 of 2004 entries
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Identification of Immune complement function as a determinant of adverse SARS-CoV-2 infection outcome.

medRxiv : the preprint server for health sciences

Ramlall V, Thangaraj PM, Meydan C, Foox J, Butler D, May B, De Freitas JK, Glicksberg BS, Mason CE, Tatonetti NP, Shapira SD.
PMID: 32511494
medRxiv. 2020 Jun 06; doi: 10.1101/2020.05.05.20092452.

Understanding the pathophysiology of SARS-CoV-2 infection is critical for therapeutics and public health intervention strategies. Viral-host interactions can guide discovery of regulators of disease outcomes, and protein structure function analysis points to several immune pathways, including complement and coagulation,...

Spend time outdoors for your brain - an in-depth longitudinal MRI study.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

Kühn S, Mascherek A, Filevich E, Lisofsky N, Becker M, Butler O, Lochstet M, Mårtensson J, Wenger E, Lindenberger U, Gallinat J.
PMID: 34231438
World J Biol Psychiatry. 2021 Jul 07;1-7. doi: 10.1080/15622975.2021.1938670. Epub 2021 Jul 07.

OBJECTIVES: The effects of nature on physical and mental health are an emerging topic in empirical research with increasing influence on practical health recommendations. Here we set out to investigate the association between spending time outdoors and brain structural...

Quantifying evidence toward pathogenicity for rare phenotypes: The case of succinate dehydrogenase genes, SDHB and SDHD.

Genetics in medicine : official journal of the American College of Medical Genetics

Garrett A, Loveday C, King L, Butler S, Robinson R, Horton C, Yussuf A, Choi S, Torr B, Durkie M, Burghel GJ, Drummond J, Berry I, Wallace A, Callaway A, Eccles D, Tischkowitz M, Tatton-Brown K, Snape K, McVeigh T, Izatt L, Woodward ER, Burnichon N, Gimenez-Roqueplo AP, Mazzarotto F, Whiffin N, Ware J, Hanson H, Pesaran T, LaDuca H, Buffet A, Maher ER, Turnbull C.
PMID: 34906457
Genet Med. 2022 Jan;24(1):41-50. doi: 10.1016/j.gim.2021.08.004. Epub 2021 Nov 30.

PURPOSE: The weight of the evidence to attach to observation of a novel rare missense variant in SDHB or SDHD in individuals with the rare neuroendocrine tumors, pheochromocytomas and paragangliomas (PCC/PGL), is uncertain.METHODS: We compared the frequency of SDHB...

A Noninvasive Method for Quantifying Cerebral Metabolic Rate of Oxygen by Hybrid PET/MRI: Validation in a Porcine Model.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Narciso L, Ssali T, Liu L, Biernaski H, Butler J, Morrison L, Hadway J, Corsaut J, Hicks JW, Langham MC, Wehrli FW, Iida H, St Lawrence K.
PMID: 33741647
J Nucl Med. 2021 Mar 19; doi: 10.2967/jnumed.120.260521. Epub 2021 Mar 19.

The gold standard for imaging the cerebral metabolic rate of oxygen (CMRO

Perspectives of GCSE students attending a psychiatry summer school in south London.

BJPsych bulletin

Wyke C, de Bernier GL, Sin Fai Lam CC, Holt C, Butler S, Rajamani APR, Wilson Jones C.
PMID: 33762046
BJPsych Bull. 2021 Apr;45(2):114-119. doi: 10.1192/bjb.2020.76.

AIMS AND METHOD: This study evaluated a pilot psychiatry summer school for GCSE students in terms of participant experience, effects on attitudes to mental illness and perception of psychiatry as a career option. This was done using the Community...

The Impact of Lockdown During the COVID-19 Outbreak on Dietary Habits in Various Population Groups: A Scoping Review.

Frontiers in nutrition

Bennett G, Young E, Butler I, Coe S.
PMID: 33748175
Front Nutr. 2021 Mar 04;8:626432. doi: 10.3389/fnut.2021.626432. eCollection 2021.

No abstract available.

Changes in inferior vena cava area represent a more sensitive metric than changes in filling pressures during experimental manipulation of intravascular volume and tone.

European journal of heart failure

Ivey-Miranda JB, Wetterling F, Gaul R, Sheridan S, Asher JL, Rao VS, Maulion C, Mahoney D, Mebazaa A, Gray AP, Burkhoff D, Cowie MR, Cox ZL, Butler J, Fudim M, McDonald K, Damman K, Borlaug BA, Testani JM.
PMID: 34837447
Eur J Heart Fail. 2021 Nov 27; doi: 10.1002/ejhf.2395. Epub 2021 Nov 27.

AIMS: Remote monitoring of pulmonary artery pressure has reduced heart failure (HF) hospitalizations in chronic HF as elevation of pulmonary artery pressure provides information that can guide treatment. The venous system is characterized by high capacitance, thus substantial increases...

Amino Acid Depletion Therapies: Starving Cancer Cells to Death.

Trends in endocrinology and metabolism: TEM

Butler M, van der Meer LT, van Leeuwen FN.
PMID: 33795176
Trends Endocrinol Metab. 2021 Jun;32(6):367-381. doi: 10.1016/j.tem.2021.03.003. Epub 2021 Mar 29.

Targeting tumor cell metabolism is an attractive form of therapy, as it may enhance treatment response in therapy resistant cancers as well as mitigate treatment-related toxicities by reducing the need for genotoxic agents. To meet their increased demand for...

Determining the maximum information gain and optimizing experimental design in neutron reflectometry using the Fisher information.

Journal of applied crystallography

Durant JH, Wilkins L, Butler K, Cooper JFK.
PMID: 34429721
J Appl Crystallogr. 2021 Jul 07;54:1100-1110. doi: 10.1107/S160057672100563X. eCollection 2021 Aug 01.

An approach based on the Fisher information (FI) is developed to quantify the maximum information gain and optimal experimental design in neutron reflectometry experiments. In these experiments, the FI can be calculated analytically and used to provide sub-second predictions...

Implantable Cardioverter-Defibrillator Eligibility After Initiation of Sacubitril/Valsartan in Chronic Heart Failure: Insights From PROVE-HF.

Circulation

Felker GM, Butler J, Ibrahim NE, Piña IL, Maisel A, Bapat D, Camacho A, Ward JH, Williamson KM, Solomon SD, Januzzi JL.
PMID: 34251893
Circulation. 2021 Jul 13;144(2):180-182. doi: 10.1161/CIRCULATIONAHA.121.054034. Epub 2021 Jul 12.

No abstract available.

The NASA Astrobiology Institute - Minority Institution Research Support Program: Strengthening the Astrobiology Community.

de la Rubia LA, Butler J, Gary T, Myles EL, Bradford K, Kirven-Brooks M, Ceballos RM, Taylor L, Bell B, Coulter G.
UIID-AD: 1005
2009;420:477-486.

This paper describes the history, purpose and successes of the NASA Astrobiology Institute Minority Institution Research Support Program (NAI-MIRS). This program is designed to provide support and training in astrobiology to a new generation of researchers from Minority Serving...

Development, Evaluation, and Dissemination of an Astrobiology Curriculum for Secondary Students: Establishing a Successful Model for Increasing the Use of Scientific Data by Underrepresented Students.

de la Rubia LA, Butler J, Gary T, Stockman S, Mumma M, Pfiffner S, Davis K, Edmonds J.
UIID-AD: 965
2009;420:471-476.

The Minority Institution Astrobiology Collaborative began working with the NASA Goddard Center for Astrobiology in 2003 to develop curriculum materials for high school chemistry and Earth science classes based on astrobiology concepts. The Astrobiology in Secondary Classrooms modules are...

Showing 1993 to 2004 of 2004 entries