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Convergent somatic mutations in metabolism genes in chronic liver disease.

Nature

Ng SWK, Rouhani FJ, Brunner SF, Brzozowska N, Aitken SJ, Yang M, Abascal F, Moore L, Nikitopoulou E, Chappell L, Leongamornlert D, Ivovic A, Robinson P, Butler T, Sanders MA, Williams N, Coorens THH, Teague J, Raine K, Butler AP, Hooks Y, Wilson B, Birtchnell N, Naylor H, Davies SE, Stratton MR, Martincorena I, Rahbari R, Frezza C, Hoare M, Campbell PJ.
PMID: 34646017
Nature. 2021 Oct;598(7881):473-478. doi: 10.1038/s41586-021-03974-6. Epub 2021 Oct 13.

The progression of chronic liver disease to hepatocellular carcinoma is caused by the acquisition of somatic mutations that affect 20-30 cancer genes

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Ng SWK, Rouhani FJ, Brunner SF, et al. Convergent somatic mutations in metabolism genes in chronic liver disease. Nature. 2021;598(7881):473-478doi: 10.1038/s41586-021-03974-6.
Ng, S. W. K., Rouhani, F. J., Brunner, S. F., Brzozowska, N., Aitken, S. J., Yang, M., Abascal, F., Moore, L., Nikitopoulou, E., Chappell, L., Leongamornlert, D., Ivovic, A., Robinson, P., Butler, T., Sanders, M. A., Williams, N., Coorens, T. H. H., Teague, J., Raine, K., Butler, A. P., Hooks, Y., Wilson, B., Birtchnell, N., Naylor, H., Davies, S. E., Stratton, M. R., Martincorena, I., Rahbari, R., Frezza, C., Hoare, M., & Campbell, P. J. (2021). Convergent somatic mutations in metabolism genes in chronic liver disease. Nature, 598(7881), 473-478. https://doi.org/10.1038/s41586-021-03974-6
Ng, Stanley W K, et al. "Convergent somatic mutations in metabolism genes in chronic liver disease." Nature vol. 598,7881 (2021): 473-478. doi: https://doi.org/10.1038/s41586-021-03974-6
Ng SWK, Rouhani FJ, Brunner SF, Brzozowska N, Aitken SJ, Yang M, Abascal F, Moore L, Nikitopoulou E, Chappell L, Leongamornlert D, Ivovic A, Robinson P, Butler T, Sanders MA, Williams N, Coorens THH, Teague J, Raine K, Butler AP, Hooks Y, Wilson B, Birtchnell N, Naylor H, Davies SE, Stratton MR, Martincorena I, Rahbari R, Frezza C, Hoare M, Campbell PJ. Convergent somatic mutations in metabolism genes in chronic liver disease. Nature. 2021 Oct;598(7881):473-478. doi: 10.1038/s41586-021-03974-6. Epub 2021 Oct 13. PMID: 34646017.
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Temporal trends and yield of clinical diagnostic genetic testing in adult neurology.

American journal of medical genetics. Part A

Guo MH, Bardakjian TM, Brzozowski MR, Scherer SS, Quinn C, Elman L, Orthmann-Murphy J, Tropea TF, Ellis CA, Gonzalez-Alegre P.
PMID: 34075706
Am J Med Genet A. 2021 Oct;185(10):2922-2928. doi: 10.1002/ajmg.a.62372. Epub 2021 Jun 02.

While genetics evaluation is increasingly utilized in adult neurology patients, its usage and efficacy are not well characterized. Here, we report our experience with 1461 consecutive patients evaluated in an adult neurogenetics clinic at a large academic medical center...

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Guo MH, Bardakjian TM, Brzozowski MR, et al. Temporal trends and yield of clinical diagnostic genetic testing in adult neurology. Am J Med Genet A. 2021;185(10):2922-2928doi: 10.1002/ajmg.a.62372.
Guo, M. H., Bardakjian, T. M., Brzozowski, M. R., Scherer, S. S., Quinn, C., Elman, L., Orthmann-Murphy, J., Tropea, T. F., Ellis, C. A., & Gonzalez-Alegre, P. (2021). Temporal trends and yield of clinical diagnostic genetic testing in adult neurology. American journal of medical genetics. Part A, 185(10), 2922-2928. https://doi.org/10.1002/ajmg.a.62372
Guo, Michael H, et al. "Temporal trends and yield of clinical diagnostic genetic testing in adult neurology." American journal of medical genetics. Part A vol. 185,10 (2021): 2922-2928. doi: https://doi.org/10.1002/ajmg.a.62372
Guo MH, Bardakjian TM, Brzozowski MR, Scherer SS, Quinn C, Elman L, Orthmann-Murphy J, Tropea TF, Ellis CA, Gonzalez-Alegre P. Temporal trends and yield of clinical diagnostic genetic testing in adult neurology. Am J Med Genet A. 2021 Oct;185(10):2922-2928. doi: 10.1002/ajmg.a.62372. Epub 2021 Jun 02. PMID: 34075706.
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Feature Importance of Stabilised Rammed Earth Components Affecting the Compressive Strength Calculated with Explainable Artificial Intelligence Tools.

Materials (Basel, Switzerland)

Anysz H, Brzozowski Ł, Kretowicz W, Narloch P.
PMID: 32443513
Materials (Basel). 2020 May 18;13(10). doi: 10.3390/ma13102317.

Cement-stabilized rammed earth (CSRE) is a sustainable construction material. The use of it allows for economizing on the cost of a structure. These two properties of CSRE are based on the fact that the soil used for the rammed...

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Anysz H, Brzozowski Ł, Kretowicz W, et al. Feature Importance of Stabilised Rammed Earth Components Affecting the Compressive Strength Calculated with Explainable Artificial Intelligence Tools. Materials (Basel). 2020;13(10)doi: 10.3390/ma13102317.
Anysz, H., Brzozowski, �. �., Kretowicz, W., & Narloch, P. (2020). Feature Importance of Stabilised Rammed Earth Components Affecting the Compressive Strength Calculated with Explainable Artificial Intelligence Tools. Materials (Basel, Switzerland), 13(10), . https://doi.org/10.3390/ma13102317
Anysz, Hubert, et al. "Feature Importance of Stabilised Rammed Earth Components Affecting the Compressive Strength Calculated with Explainable Artificial Intelligence Tools." Materials (Basel, Switzerland) vol. 13,10 (2020). doi: https://doi.org/10.3390/ma13102317
Anysz H, Brzozowski Ł, Kretowicz W, Narloch P. Feature Importance of Stabilised Rammed Earth Components Affecting the Compressive Strength Calculated with Explainable Artificial Intelligence Tools. Materials (Basel). 2020 May 18;13(10). doi: 10.3390/ma13102317. PMID: 32443513; PMCID: PMC7288123.
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Radiolocation Devices for Detection and Tracking Small High-Speed Ballistic Objects-Features, Applications, and Methods of Tests.

Sensors (Basel, Switzerland)

Brzozowski M, Pakowski M, Nowakowski M, Myszka M, Michalczewski M.
PMID: 31817388
Sensors (Basel). 2019 Dec 05;19(24). doi: 10.3390/s19245362.

This article describes radiolocation devices dedicated to the detection and tracking of small high-speed ballistic objects and multifunctional radars. This functionality is implemented by applying space search technology and adaptive algorithms for detection and tracking of air objects in...

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Brzozowski M, Pakowski M, Nowakowski M, et al. Radiolocation Devices for Detection and Tracking Small High-Speed Ballistic Objects-Features, Applications, and Methods of Tests. Sensors (Basel). 2019;19(24)doi: 10.3390/s19245362.
Brzozowski, M., Pakowski, M., Nowakowski, M., Myszka, M., & Michalczewski, M. (2019). Radiolocation Devices for Detection and Tracking Small High-Speed Ballistic Objects-Features, Applications, and Methods of Tests. Sensors (Basel, Switzerland), 19(24), . https://doi.org/10.3390/s19245362
Brzozowski, Marek, et al. "Radiolocation Devices for Detection and Tracking Small High-Speed Ballistic Objects-Features, Applications, and Methods of Tests." Sensors (Basel, Switzerland) vol. 19,24 (2019). doi: https://doi.org/10.3390/s19245362
Brzozowski M, Pakowski M, Nowakowski M, Myszka M, Michalczewski M. Radiolocation Devices for Detection and Tracking Small High-Speed Ballistic Objects-Features, Applications, and Methods of Tests. Sensors (Basel). 2019 Dec 05;19(24). doi: 10.3390/s19245362. PMID: 31817388; PMCID: PMC6960890.
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Melatonin ameliorates aging-related impaired angiogenesis in gastric endothelial cells via local actions on mitochondria and VEGF-survivin signaling.

American journal of physiology. Gastrointestinal and liver physiology

Ahluwalia A, Patel K, Hoa N, Brzozowska I, Jones MK, Tarnawski AS.
PMID: 34668398
Am J Physiol Gastrointest Liver Physiol. 2021 Dec 01;321(6):G682-G689. doi: 10.1152/ajpgi.00101.2021. Epub 2021 Oct 20.

Tissue injury healing is impaired in aging, and this impairment is caused in part by reduced angiogenesis. Melatonin, a neuroendocrine hormone that regulates sleep and circadian rhythm, is also produced in the gastrointestinal tract. The expression of melatonin receptors...

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Ahluwalia A, Patel K, Hoa N, et al. Melatonin ameliorates aging-related impaired angiogenesis in gastric endothelial cells via local actions on mitochondria and VEGF-survivin signaling. Am J Physiol Gastrointest Liver Physiol. 2021;321(6):G682-G689doi: 10.1152/ajpgi.00101.2021.
Ahluwalia, A., Patel, K., Hoa, N., Brzozowska, I., Jones, M. K., & Tarnawski, A. S. (2021). Melatonin ameliorates aging-related impaired angiogenesis in gastric endothelial cells via local actions on mitochondria and VEGF-survivin signaling. American journal of physiology. Gastrointestinal and liver physiology, 321(6), G682-G689. https://doi.org/10.1152/ajpgi.00101.2021
Ahluwalia, Amrita, et al. "Melatonin ameliorates aging-related impaired angiogenesis in gastric endothelial cells via local actions on mitochondria and VEGF-survivin signaling." American journal of physiology. Gastrointestinal and liver physiology vol. 321,6 (2021): G682-G689. doi: https://doi.org/10.1152/ajpgi.00101.2021
Ahluwalia A, Patel K, Hoa N, Brzozowska I, Jones MK, Tarnawski AS. Melatonin ameliorates aging-related impaired angiogenesis in gastric endothelial cells via local actions on mitochondria and VEGF-survivin signaling. Am J Physiol Gastrointest Liver Physiol. 2021 Dec 01;321(6):G682-G689. doi: 10.1152/ajpgi.00101.2021. Epub 2021 Oct 20. PMID: 34668398.
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Effect of Supercritical Extract from Black Poplar and Basket Willow on the Quality of Natural and Probiotic Drinkable Yogurt.

Animals : an open access journal from MDPI

Walter M, Brzozowski B, Adamczak M.
PMID: 34680016
Animals (Basel). 2021 Oct 19;11(10). doi: 10.3390/ani11102997.

Yogurt is a fermented milk drink produced by

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Walter M, Brzozowski B, Adamczak M. Effect of Supercritical Extract from Black Poplar and Basket Willow on the Quality of Natural and Probiotic Drinkable Yogurt. Animals (Basel). 2021;11(10)doi: 10.3390/ani11102997.
Walter, M., Brzozowski, B., & Adamczak, M. (2021). Effect of Supercritical Extract from Black Poplar and Basket Willow on the Quality of Natural and Probiotic Drinkable Yogurt. Animals : an open access journal from MDPI, 11(10), . https://doi.org/10.3390/ani11102997
Walter, Marcin, et al. "Effect of Supercritical Extract from Black Poplar and Basket Willow on the Quality of Natural and Probiotic Drinkable Yogurt." Animals : an open access journal from MDPI vol. 11,10 (2021). doi: https://doi.org/10.3390/ani11102997
Walter M, Brzozowski B, Adamczak M. Effect of Supercritical Extract from Black Poplar and Basket Willow on the Quality of Natural and Probiotic Drinkable Yogurt. Animals (Basel). 2021 Oct 19;11(10). doi: 10.3390/ani11102997. PMID: 34680016; PMCID: PMC8532730.
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The Effect of Plant Additives on the Stability of Polyphenols in Dried Black Chokeberry (.

Foods (Basel, Switzerland)

Sidor A, Drożdżyńska A, Brzozowska A, Gramza-Michałowska A.
PMID: 33375255
Foods. 2020 Dec 26;10(1). doi: 10.3390/foods10010044.

Chokeberry fruit exhibits a high level of pro-health potential, associated with a significant amount of polyphenol content and antioxidant activity. The fruit is easily perishable and therefore needs to be processed in short order to ensure its availability throughout...

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Sidor A, Drożdżyńska A, Brzozowska A, et al. The Effect of Plant Additives on the Stability of Polyphenols in Dried Black Chokeberry (. Foods. 2020;10(1)doi: 10.3390/foods10010044.
Sidor, A., Drożdżyńska, A., Brzozowska, A., & Gramza-Michałowska, A. (2020). The Effect of Plant Additives on the Stability of Polyphenols in Dried Black Chokeberry (. Foods (Basel, Switzerland), 10(1), . https://doi.org/10.3390/foods10010044
Sidor, Andrzej, et al. "The Effect of Plant Additives on the Stability of Polyphenols in Dried Black Chokeberry (." Foods (Basel, Switzerland) vol. 10,1 (2020). doi: https://doi.org/10.3390/foods10010044
Sidor A, Drożdżyńska A, Brzozowska A, Gramza-Michałowska A. The Effect of Plant Additives on the Stability of Polyphenols in Dried Black Chokeberry (. Foods. 2020 Dec 26;10(1). doi: 10.3390/foods10010044. PMID: 33375255; PMCID: PMC7824072.
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Recurrent or persistent salivary gland enlargement in children: When is it Sjögren's?.

Seminars in arthritis and rheumatism

Pomorska A, Świętoń D, Lieberman SM, Bryl E, Kosiak W, Pęksa R, Chorążewicz J, Kochańska B, Kowalska-Skabara J, Szumera M, Brzoznowski W, Jaworski R, Irga-Jaworska N.
PMID: 35000785
Semin Arthritis Rheum. 2021 Dec 30; doi: 10.1016/j.semarthrit.2021.11.011. Epub 2021 Dec 30.

OBJECTIVES: To describe characteristic features in children with recurrent or persistent salivary gland enlargement and to propose a diagnostic algorithm with specific consideration for Sjögren's disease (SD).METHODS: In this single-center, prospective study, 45 patients

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Pomorska A, Świętoń D, Lieberman SM, et al. Recurrent or persistent salivary gland enlargement in children: When is it Sjögren's?. Semin Arthritis Rheum. 2021;doi: 10.1016/j.semarthrit.2021.11.011.
Pomorska, A., Świętoń, D., Lieberman, S. M., Bryl, E., Kosiak, W., Pęksa, R., Chorążewicz, J., Kochańska, B., Kowalska-Skabara, J., Szumera, M., Brzoznowski, W., Jaworski, R., & Irga-Jaworska, N. (2021). Recurrent or persistent salivary gland enlargement in children: When is it Sjögren's?. Seminars in arthritis and rheumatism, . https://doi.org/10.1016/j.semarthrit.2021.11.011
Pomorska, Anna, et al. "Recurrent or persistent salivary gland enlargement in children: When is it Sjögren's?." Seminars in arthritis and rheumatism vol. (2021). doi: https://doi.org/10.1016/j.semarthrit.2021.11.011
Pomorska A, Świętoń D, Lieberman SM, Bryl E, Kosiak W, Pęksa R, Chorążewicz J, Kochańska B, Kowalska-Skabara J, Szumera M, Brzoznowski W, Jaworski R, Irga-Jaworska N. Recurrent or persistent salivary gland enlargement in children: When is it Sjögren's?. Semin Arthritis Rheum. 2021 Dec 30; doi: 10.1016/j.semarthrit.2021.11.011. Epub 2021 Dec 30. PMID: 35000785.
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Lead Dependent Tricuspid Valve Dysfunction-Risk Factors, Improvement after Transvenous Lead Extraction and Long-Term Prognosis.

Journal of clinical medicine

Polewczyk A, Jacheć W, Nowosielecka D, Tomaszewski A, Brzozowski W, Szczęśniak-Stańczyk D, Duda K, Kutarski A.
PMID: 35011829
J Clin Med. 2021 Dec 24;11(1). doi: 10.3390/jcm11010089.

BACKGROUND: Lead-related tricuspid valve dysfunction (LDTVD) has not been studied in a large population and its management remains controversial.METHODS: An analysis of the clinical data of 2678 patients undergoing transvenous lead extraction (TLE) in years 2008-2021 was conducted, with...

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Polewczyk A, Jacheć W, Nowosielecka D, et al. Lead Dependent Tricuspid Valve Dysfunction-Risk Factors, Improvement after Transvenous Lead Extraction and Long-Term Prognosis. J Clin Med. 2021;11(1)doi: 10.3390/jcm11010089.
Polewczyk, A., Jacheć, W., Nowosielecka, D., Tomaszewski, A., Brzozowski, W., Szczęśniak-Stańczyk, D., Duda, K., & Kutarski, A. (2021). Lead Dependent Tricuspid Valve Dysfunction-Risk Factors, Improvement after Transvenous Lead Extraction and Long-Term Prognosis. Journal of clinical medicine, 11(1), . https://doi.org/10.3390/jcm11010089
Polewczyk, Anna, et al. "Lead Dependent Tricuspid Valve Dysfunction-Risk Factors, Improvement after Transvenous Lead Extraction and Long-Term Prognosis." Journal of clinical medicine vol. 11,1 (2021). doi: https://doi.org/10.3390/jcm11010089
Polewczyk A, Jacheć W, Nowosielecka D, Tomaszewski A, Brzozowski W, Szczęśniak-Stańczyk D, Duda K, Kutarski A. Lead Dependent Tricuspid Valve Dysfunction-Risk Factors, Improvement after Transvenous Lead Extraction and Long-Term Prognosis. J Clin Med. 2021 Dec 24;11(1). doi: 10.3390/jcm11010089. PMID: 35011829.
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Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention.

JMIR medical informatics

Lobach DF, Johns EB, Halpenny B, Saunders TA, Brzozowski J, Del Fiol G, Berry DL, Braun IM, Finn K, Wolfe J, Abrahm JL, Cooley ME.
PMID: 27826132
JMIR Med Inform. 2016 Nov 08;4(4):e36. doi: 10.2196/medinform.5728.

BACKGROUND: Management of uncontrolled symptoms is an important component of quality cancer care. Clinical guidelines are available for optimal symptom management, but are not often integrated into the front lines of care. The use of clinical decision support (CDS)...

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Lobach DF, Johns EB, Halpenny B, et al. Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention. JMIR Med Inform. 2016;4(4):e36doi: 10.2196/medinform.5728.
Lobach, D. F., Johns, E. B., Halpenny, B., Saunders, T. A., Brzozowski, J., Del Fiol, G., Berry, D. L., Braun, I. M., Finn, K., Wolfe, J., Abrahm, J. L., & Cooley, M. E. (2016). Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention. JMIR medical informatics, 4(4), e36. https://doi.org/10.2196/medinform.5728
Lobach, David F, et al. "Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention." JMIR medical informatics vol. 4,4 (2016): e36. doi: https://doi.org/10.2196/medinform.5728
Lobach DF, Johns EB, Halpenny B, Saunders TA, Brzozowski J, Del Fiol G, Berry DL, Braun IM, Finn K, Wolfe J, Abrahm JL, Cooley ME. Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention. JMIR Med Inform. 2016 Nov 08;4(4):e36. doi: 10.2196/medinform.5728. PMID: 27826132; PMCID: PMC5120240.
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Bioelectrical impedance phase angle as a prognostic indicator of survival in head-and-neck cancer.

Current oncology (Toronto, Ont.)

Władysiuk MS, Mlak R, Morshed K, Surtel W, Brzozowska A, Małecka-Massalska T.
PMID: 27803609
Curr Oncol. 2016 Oct;23(5):e481-e487. doi: 10.3747/co.23.3181. Epub 2016 Oct 25.

BACKGROUND: Phase angle could be an alternative to subjective global assessment for the assessment of nutrition status in patients with head-and-neck cancer.METHODS: We prospectively evaluated a cohort of 75 stage iiib and iv head-and-neck patients treated at the Otolaryngology...

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Władysiuk MS, Mlak R, Morshed K, et al. Bioelectrical impedance phase angle as a prognostic indicator of survival in head-and-neck cancer. Curr Oncol. 2016;23(5):e481-e487doi: 10.3747/co.23.3181.
Władysiuk, M. S., Mlak, R., Morshed, K., Surtel, W., Brzozowska, A., & Małecka-Massalska, T. (2016). Bioelectrical impedance phase angle as a prognostic indicator of survival in head-and-neck cancer. Current oncology (Toronto, Ont.), 23(5), e481-e487. https://doi.org/10.3747/co.23.3181
Władysiuk, M S, et al. "Bioelectrical impedance phase angle as a prognostic indicator of survival in head-and-neck cancer." Current oncology (Toronto, Ont.) vol. 23,5 (2016): e481-e487. doi: https://doi.org/10.3747/co.23.3181
Władysiuk MS, Mlak R, Morshed K, Surtel W, Brzozowska A, Małecka-Massalska T. Bioelectrical impedance phase angle as a prognostic indicator of survival in head-and-neck cancer. Curr Oncol. 2016 Oct;23(5):e481-e487. doi: 10.3747/co.23.3181. Epub 2016 Oct 25. PMID: 27803609; PMCID: PMC5081021.
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φYeO3-12 phage tail fiber Gp17 as a promising high specific tool for recognition of Yersinia enterocolitica pathogenic serotype O:3.

AMB Express

Filik K, Szermer-Olearnik B, Niedziółka-Jönson J, Roźniecka E, Ciekot J, Pyra A, Matyjaszczyk I, Skurnik M, Brzozowska E.
PMID: 34989907
AMB Express. 2022 Jan 06;12(1):1. doi: 10.1186/s13568-021-01341-2.

Yersiniosis is an infectious zoonotic disease caused by two enteropathogenic species of Gram-negative genus Yersinia: Yersinia enterocolitica and Yersinia pseudotuberculosis. Pigs and other wild and domestic animals are reservoirs for these bacteria. Infection is usually spread to humans by...

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Filik K, Szermer-Olearnik B, Niedziółka-Jönson J, et al. φYeO3-12 phage tail fiber Gp17 as a promising high specific tool for recognition of Yersinia enterocolitica pathogenic serotype O:3. AMB Express. 2022;12(1):1doi: 10.1186/s13568-021-01341-2.
Filik, K., Szermer-Olearnik, B., Niedziółka-Jönson, J., Roźniecka, E., Ciekot, J., Pyra, A., Matyjaszczyk, I., Skurnik, M., & Brzozowska, E. (2022). φYeO3-12 phage tail fiber Gp17 as a promising high specific tool for recognition of Yersinia enterocolitica pathogenic serotype O:3. AMB Express, 12(1), 1. https://doi.org/10.1186/s13568-021-01341-2
Filik, Karolina, et al. "φYeO3-12 phage tail fiber Gp17 as a promising high specific tool for recognition of Yersinia enterocolitica pathogenic serotype O:3." AMB Express vol. 12,1 (2022): 1. doi: https://doi.org/10.1186/s13568-021-01341-2
Filik K, Szermer-Olearnik B, Niedziółka-Jönson J, Roźniecka E, Ciekot J, Pyra A, Matyjaszczyk I, Skurnik M, Brzozowska E. φYeO3-12 phage tail fiber Gp17 as a promising high specific tool for recognition of Yersinia enterocolitica pathogenic serotype O:3. AMB Express. 2022 Jan 06;12(1):1. doi: 10.1186/s13568-021-01341-2. PMID: 34989907.
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