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Showing 13 to 15 of 15 entries
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Higher Desolvation Energy Reduces Molecular Recognition in Multi-Drug Resistant HIV-1 Protease.

Biology

Wang Y, Dewdney TG, Liu Z, Reiter SJ, Brunzelle JS, Kovari IA, Kovari LC.
PMID: 24832048
Biology (Basel). 2012 May 31;1(1):81-93. doi: 10.3390/biology1010081.

Designing HIV-1 protease inhibitors that overcome drug-resistance is still a challenging task. In this study, four clinical isolates of multi-drug resistant HIV-1 proteases that exhibit resistance to all the US FDA-approved HIV-1 protease inhibitors and also reduce the substrate...

Evaluating the cardiovascular effects of the thiazolidinediones and their place in the management of type 2 diabetes in relation to the metabolic syndrome.

Metabolic syndrome and related disorders

Drexler AJ, Nesto RW, Abrahamson MJ, Bakris G, Bell D, Brunzell J, Dandona P, Davidson J, Fonseca V, Fowler M, Frye R, Giles T, Haffner S, Hollenberg N, Hsueh W, Law R, Plutzky J, Ratner R, Reusch J, Selwyn A, Sowers J, Wyne K, Young LH.
PMID: 18370723
Metab Syndr Relat Disord. 2005;3(2):147-73. doi: 10.1089/met.2005.3.147.

BACKGROUND: The aim of this work was to review evidence on the contribution of the metabolic syndrome to diabetes and atherosclerosis, to evaluate the effects of the thiazolidinediones (TZDs) on cardiovascular risk, and to assess the clinical use of...

Cutaneous Pedal Manifestations in Patient With Hepatitis C Virus-Associated Cryoglobulinemia: Case Report and Review of Literature.

The international journal of lower extremity wounds

McEneaney PA, Nicklas BJ, Kuba JL, Rundell JD.
PMID: 33089718
Int J Low Extrem Wounds. 2020 Oct 22;1534734620961893. doi: 10.1177/1534734620961893. Epub 2020 Oct 22.

Cryoglobulinemia is an uncommon blood dyscrasia that can manifest itself in the lower extremity. Due to the insidious nature of this disease, dermatological symptoms and ulcerations can easily be mistaken for more common entities. The authors present an overview...

Showing 13 to 15 of 15 entries