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Showing 517 to 523 of 523 entries
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Persistent Dark Cones in Oligocone Trichromacy Revealed by Multimodal Adaptive Optics Ophthalmoscopy.

Frontiers in aging neuroscience

Li J, Liu T, Flynn OJ, Turriff A, Liu Z, Ullah E, Liu J, Dubra A, Johnson MA, Brooks BP, Hufnagel RB, Hammer DX, Huryn LA, Jeffrey BG, Tam J.
PMID: 33767618
Front Aging Neurosci. 2021 Mar 09;13:629214. doi: 10.3389/fnagi.2021.629214. eCollection 2021.

Dark cone photoreceptors, defined as those with diminished or absent reflectivity when observed with adaptive optics (AO) ophthalmoscopy, are increasingly reported in retinal disorders. However, their structural and functional impact remain unclear. Here, we report a 3-year longitudinal study...

Smartphone Thermal Imaging in the Detection of Testicular Ischemia.

Urology

Brooks JP, Brooks JM, Seals T.
PMID: 33689763
Urology. 2021 Mar 06; doi: 10.1016/j.urology.2021.02.031. Epub 2021 Mar 06.

OBJECTIVE: To evaluate smartphone thermal imaging as a point of care test in the detection of testicular ischemia. Thermal imaging detects the infrared (heat) pattern of an object and the technology is now available as an inexpensive attachment to...

Slowing the loss of physical function in amyotrophic lateral sclerosis with edaravone: Post hoc analysis of ALSFRS-R item scores in pivotal study MCI186-19.

Muscle & nerve

Brooks BR, Pioro EP, Katz J, Takahashi F, Takei K, Zhang J, Apple S.
PMID: 34816454
Muscle Nerve. 2022 Feb;65(2):180-186. doi: 10.1002/mus.27467. Epub 2021 Dec 10.

INTRODUCTION: Phase 3 study MCI186-19 demonstrated less loss of physical function with edaravone versus placebo, as measured by the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) total score. A 1-point drop in an individual ALSFRS-R item may be...

Green Chemistry: A Framework for a Sustainable Future.

ACS omega

Ganesh KN, Zhang D, Miller SJ, Rossen K, Chirik PJ, Kozlowski MC, Zimmerman JB, Brooks BW, Savage PE, Allen DT, Voutchkova-Kostal AM.
PMID: 34235294
ACS Omega. 2021 Jun 15;6(25):16254-16258. doi: 10.1021/acsomega.1c03011. eCollection 2021 Jun 29.

No abstract available.

Disrupted cognitive development following pediatric acquired demyelinating syndromes: a longitudinal study.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence

De Somma E, O'Mahony J, Brown RA, Brooks BL, Yeh EA, Cardenas de La Parra A, Arnold D, Collins DL, Maranzano J, Narayanan S, Marrie RA, Bar-Or A, Banwell B, Till C.
PMID: 34872458
Child Neuropsychol. 2021 Dec 06;1-22. doi: 10.1080/09297049.2021.2002289. Epub 2021 Dec 06.

Long-term cognitive deficits have been observed in some children who experience an acquired demyelinating syndrome (ADS). We examined changes in cognitive functioning over the first two years following incident ADS andtested whether normalized brain and thalamic volume accounted for...

Radicava/Edaravone Findings in Biomarkers From Amyotrophic Lateral Sclerosis (REFINE-ALS): Protocol and Study Design.

Neurology. Clinical practice

Berry J, Brooks B, Genge A, Heiman-Patterson T, Appel S, Benatar M, Bowser R, Cudkowicz M, Gooch C, Shefner J, Westra J, Agnese W, Merrill C, Nelson S, Apple S.
PMID: 34476128
Neurol Clin Pract. 2021 Aug;11(4):e472-e479. doi: 10.1212/CPJ.0000000000000968.

OBJECTIVES: To identify putative biomarkers that may serve as quantifiable, biological, nonclinical measures of the pharmacodynamic effect of edaravone in amyotrophic lateral sclerosis (ALS) and to report real-world treatment outcomes.METHODS: This is a prospective, observational, longitudinal, multicenter (up to...

Long-Term Functional Decline Following Vascular Surgery Among Vulnerable Adults.

Annals of vascular surgery

DeAngelo MM, Peacock JB, Holeman TA, Maloney M, Beckstrom J, Brooke BS.
PMID: 33895257
Ann Vasc Surg. 2021 Oct;76:87-94. doi: 10.1016/j.avsg.2021.04.002. Epub 2021 Apr 22.

BACKGROUND: Identification of high-risk patients that may experience functional decline following surgery poses a challenge to healthcare providers. The Vulnerable Elders Survey (VES-13) is a patient-reported tool designed to identify risk for health deterioration based on age, self-rated health,...

Showing 517 to 523 of 523 entries