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Showing 37 to 48 of 65 entries
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Sepsis-Associated Encephalopathy: From Delirium to Dementia?.

Journal of clinical medicine

Chung HY, Wickel J, Brunkhorst FM, Geis C.
PMID: 32150970
J Clin Med. 2020 Mar 05;9(3). doi: 10.3390/jcm9030703.

Sepsis is a major cause of death in intensive care units worldwide. The acute phase of sepsis is often accompanied by sepsis-associated encephalopathy, which is highly associated with increased mortality. Moreover, in the chronic phase, more than 50% of...

Short fatigue questionnaire: Screening for severe fatigue.

Journal of psychosomatic research

Penson A, van Deuren S, Worm-Smeitink M, Bronkhorst E, van den Hoogen FHJ, van Engelen BGM, Peters M, Bleijenberg G, Vercoulen JH, Blijlevens N, van Dulmen-den Broeder E, Loonen J, Knoop H.
PMID: 32890861
J Psychosom Res. 2020 Aug 28;137:110229. doi: 10.1016/j.jpsychores.2020.110229. Epub 2020 Aug 28.

OBJECTIVE: To determine psychometric properties, a cut-off score for severe fatigue and normative data for the 4-item Short Fatigue Questionnaire (SFQ) derived from the multi-dimensional fatigue questionnaire Checklist Individual Strength (CIS).METHODS: Data of previous studies investigating the prevalence of...

Contextualising the Perceptions of Pharmacists Practicing Clinical Pharmacy in South Africa-Do We Practice what We Preach?.

Frontiers in pharmacology

Bronkhorst E, Schellack N, Gous AGS.
PMID: 34925004
Front Pharmacol. 2021 Dec 03;12:734654. doi: 10.3389/fphar.2021.734654. eCollection 2021.

The National Department of Health published their Quality Standards for Healthcare Establishments in South Africa and introduced the National Health Insurance, with the pilot phase that commenced in 2012. The system requires an adequate supply of pharmaceutical personnel and...

Practice Guidelines for Clinical Pharmacists in Middle to Low Income Countries.

Frontiers in pharmacology

Bronkhorst E, Gous AGS, Schellack N.
PMID: 32695002
Front Pharmacol. 2020 Jun 30;11:978. doi: 10.3389/fphar.2020.00978. eCollection 2020.

The profession of pharmacy is maturing as a clinical profession in South Africa and has experienced significant development over the past 10 years. The development of clinical pharmacy in Southern Africa started in the late 1980s. The Director-General of...

Evaluation of Watchful Waiting and Tumor Behavior in Patients With Basal Cell Carcinoma: An Observational Cohort Study of 280 Basal Cell Carcinomas in 89 Patients.

JAMA dermatology

van Winden MEC, Hetterschijt CRM, Bronkhorst EM, van de Kerkhof PCM, de Jong EMGJ, Lubeek SFK.
PMID: 34495284
JAMA Dermatol. 2021 Oct 01;157(10):1174-1181. doi: 10.1001/jamadermatol.2021.3020.

IMPORTANCE: Few studies have examined watchful waiting (WW) in patients with basal cell carcinoma (BCC), although this approach might be suitable in patients who might not live long enough to benefit from treatment.OBJECTIVE: To evaluate reasons for WW and...

Early detection of cancer using circulating tumor DNA: biological, physiological and analytical considerations.

Critical reviews in clinical laboratory sciences

Bronkhorst AJ, Ungerer V, Holdenrieder S.
PMID: 31865831
Crit Rev Clin Lab Sci. 2019 Dec 22;1-17. doi: 10.1080/10408363.2019.1700902. Epub 2019 Dec 22.

Early diagnosis of cancer improves the efficacy of curative therapies. However, due to the difficulties involved in distinguishing between small early-stage tumors and normal biological variation, early detection of cancer is an extremely challenging task and there are currently...

Annoyance by transportation noise: The effects of source identity and tonal components.

The Journal of the Acoustical Society of America

White K, Bronkhorst AW, Meeter M.
PMID: 28599543
J Acoust Soc Am. 2017 May;141(5):3137. doi: 10.1121/1.4982921.

Aircraft noise is consistently rated as more annoying than noise from other sources with similar intensity. In three experiments, it was investigated whether this penalty is due to the source identity of the noise. In the first experiment, four...

Adjustments to the preanalytical phase of quantitative cell-free DNA analysis.

Data in brief

Bronkhorst AJ, Aucamp J, Pretorius PJ.
PMID: 26862578
Data Brief. 2015 Dec 17;6:326-9. doi: 10.1016/j.dib.2015.12.009. eCollection 2016 Mar.

Evaluating the kinetics of cell-free DNA (cfDNA) in the blood of cancer patients could be a strong auxiliary component to the molecular characterization of cfDNA, but its potential clinical significance is obscured by the absence of an analytical consensus....

Routine lung ultrasound to detect postoperative pulmonary complications following major abdominal surgery: a prospective observational feasibility study.

The ultrasound journal

Touw HR, Schuitemaker AE, Daams F, van der Peet DL, Bronkhorst EM, Schober P, Boer C, Tuinman PR.
PMID: 31523784
Ultrasound J. 2019 Sep 16;11(1):20. doi: 10.1186/s13089-019-0135-6.

BACKGROUND: Postoperative pulmonary complications after major abdominal surgery are associated with adverse outcome. The diagnostic accuracy of chest X-rays (CXR) to detect pulmonary disorders is limited. Alternatively, lung ultrasound (LUS) is an established evidence-based point-of-care diagnostic modality which outperforms...

Phyllomedusa bicolor skin secretion and the Kambô ritual.

The journal of venomous animals and toxins including tropical diseases

den Brave PS, Bruins E, Bronkhorst MW.
PMID: 26413084
J Venom Anim Toxins Incl Trop Dis. 2014 Sep 02;20:40. doi: 10.1186/1678-9199-20-40. eCollection 2014.

The ritual of Kambô or Sapo is a type of voluntary envenomation. During this purification ritual a shaman healer, from various South American countries, deliberately burns the right shoulder with a glowing stick from a fireplace. Excretions of Phyllomedusa...

Association of Programmed Death 1 Protein Ligand (PD-L1) Expression With Prognosis in Merkel Cell Carcinoma.

Frontiers in medicine

Hanna GJ, Kacew AJ, Tanguturi AR, Grote HJ, Vergara V, Brunkhorst B, Rabinowits G, Thakuria M, LeBoeuf NR, Ihling C, DeCaprio JA, Lorch JH.
PMID: 32582722
Front Med (Lausanne). 2020 Jun 05;7:198. doi: 10.3389/fmed.2020.00198. eCollection 2020.

No abstract available.

The emerging role of cell-free DNA as a molecular marker for cancer management.

Biomolecular detection and quantification

Bronkhorst AJ, Ungerer V, Holdenrieder S.
PMID: 30923679
Biomol Detect Quantif. 2019 Mar 18;17:100087. doi: 10.1016/j.bdq.2019.100087. eCollection 2019 Mar.

An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and monitoring. However, harnessing the full potential of cfDNA requires (i) the optimization and...

Showing 37 to 48 of 65 entries