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Showing 25 to 36 of 166 entries
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Homozygous mutation in .

Journal of medical genetics

Ravindran E, Gutierrez de Velazco C, Ghazanfar A, Kraemer N, Zaqout S, Waheed A, Hanif M, Mughal S, Prigione A, Li N, Fang X, Hu H, Kaindl AM.
PMID: 34059554
J Med Genet. 2021 May 31; doi: 10.1136/jmedgenet-2020-107518. Epub 2021 May 31.

BACKGROUND: Minichromosomal maintenance (MCM) complex components 2, 4, 5 and 6 have been linked to human disease with phenotypes including microcephaly and intellectual disability. The MCM complex has DNA helicase activity and is thereby important for the initiation and...

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Ravindran E, Gutierrez de Velazco C, Ghazanfar A, et al. Homozygous mutation in . J Med Genet. 2021;doi: 10.1136/jmedgenet-2020-107518.
Ravindran, E., Gutierrez de Velazco, C., Ghazanfar, A., Kraemer, N., Zaqout, S., Waheed, A., Hanif, M., Mughal, S., Prigione, A., Li, N., Fang, X., Hu, H., & Kaindl, A. M. (2021). Homozygous mutation in . Journal of medical genetics, . https://doi.org/10.1136/jmedgenet-2020-107518
Ravindran, Ethiraj, et al. "Homozygous mutation in ." Journal of medical genetics vol. (2021). doi: https://doi.org/10.1136/jmedgenet-2020-107518
Ravindran E, Gutierrez de Velazco C, Ghazanfar A, Kraemer N, Zaqout S, Waheed A, Hanif M, Mughal S, Prigione A, Li N, Fang X, Hu H, Kaindl AM. Homozygous mutation in . J Med Genet. 2021 May 31; doi: 10.1136/jmedgenet-2020-107518. Epub 2021 May 31. PMID: 34059554.
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Implementing social network analysis to understand the socioecology of wildlife co-occurrence and joint interactions with humans in anthropogenic environments.

The Journal of animal ecology

Balasubramaniam KN, Kaburu SSK, Marty PR, Beisner BA, Bliss-Moreau E, Arlet ME, Ruppert N, Ismail A, Anuar Mohd Sah S, Mohan L, Rattan S, Kodandaramaiah U, McCowan B.
PMID: 34453852
J Anim Ecol. 2021 Dec;90(12):2819-2833. doi: 10.1111/1365-2656.13584. Epub 2021 Sep 06.

Human population expansion into wildlife habitats has increased interest in the behavioural ecology of human-wildlife interactions. To date, however, the socioecological factors that determine whether, when or where wild animals take risks by interacting with humans and anthropogenic factors...

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Balasubramaniam KN, Kaburu SSK, Marty PR, et al. Implementing social network analysis to understand the socioecology of wildlife co-occurrence and joint interactions with humans in anthropogenic environments. J Anim Ecol. 2021;90(12):2819-2833doi: 10.1111/1365-2656.13584.
Balasubramaniam, K. N., Kaburu, S. S. K., Marty, P. R., Beisner, B. A., Bliss-Moreau, E., Arlet, M. E., Ruppert, N., Ismail, A., Anuar Mohd Sah, S., Mohan, L., Rattan, S., Kodandaramaiah, U., & McCowan, B. (2021). Implementing social network analysis to understand the socioecology of wildlife co-occurrence and joint interactions with humans in anthropogenic environments. The Journal of animal ecology, 90(12), 2819-2833. https://doi.org/10.1111/1365-2656.13584
Balasubramaniam, Krishna N, et al. "Implementing social network analysis to understand the socioecology of wildlife co-occurrence and joint interactions with humans in anthropogenic environments." The Journal of animal ecology vol. 90,12 (2021): 2819-2833. doi: https://doi.org/10.1111/1365-2656.13584
Balasubramaniam KN, Kaburu SSK, Marty PR, Beisner BA, Bliss-Moreau E, Arlet ME, Ruppert N, Ismail A, Anuar Mohd Sah S, Mohan L, Rattan S, Kodandaramaiah U, McCowan B. Implementing social network analysis to understand the socioecology of wildlife co-occurrence and joint interactions with humans in anthropogenic environments. J Anim Ecol. 2021 Dec;90(12):2819-2833. doi: 10.1111/1365-2656.13584. Epub 2021 Sep 06. PMID: 34453852.
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Cotargeting of miR-126-3p and miR-221-3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling.

Molecular oncology

Di Paolo D, Pontis F, Moro M, Centonze G, Bertolini G, Milione M, Mensah M, Segale M, Petraroia I, Borzi C, Suatoni P, Brignole C, Perri P, Ponzoni M, Pastorino U, Sozzi G, Fortunato O.
PMID: 34107168
Mol Oncol. 2021 Nov;15(11):2969-2988. doi: 10.1002/1878-0261.13036. Epub 2021 Jul 21.

Lung cancer is the leading cause of cancer-related death worldwide. Late diagnosis and metastatic dissemination contribute to its low survival rate. Since microRNA (miRNA) deregulation triggers lung carcinogenesis, miRNAs might represent an interesting therapeutic tool for lung cancer management....

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Di Paolo D, Pontis F, Moro M, et al. Cotargeting of miR-126-3p and miR-221-3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling. Mol Oncol. 2021;15(11):2969-2988doi: 10.1002/1878-0261.13036.
Di Paolo, D., Pontis, F., Moro, M., Centonze, G., Bertolini, G., Milione, M., Mensah, M., Segale, M., Petraroia, I., Borzi, C., Suatoni, P., Brignole, C., Perri, P., Ponzoni, M., Pastorino, U., Sozzi, G., & Fortunato, O. (2021). Cotargeting of miR-126-3p and miR-221-3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling. Molecular oncology, 15(11), 2969-2988. https://doi.org/10.1002/1878-0261.13036
Di Paolo, Daniela, et al. "Cotargeting of miR-126-3p and miR-221-3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling." Molecular oncology vol. 15,11 (2021): 2969-2988. doi: https://doi.org/10.1002/1878-0261.13036
Di Paolo D, Pontis F, Moro M, Centonze G, Bertolini G, Milione M, Mensah M, Segale M, Petraroia I, Borzi C, Suatoni P, Brignole C, Perri P, Ponzoni M, Pastorino U, Sozzi G, Fortunato O. Cotargeting of miR-126-3p and miR-221-3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling. Mol Oncol. 2021 Nov;15(11):2969-2988. doi: 10.1002/1878-0261.13036. Epub 2021 Jul 21. PMID: 34107168; PMCID: PMC8564655.
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New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope.

Heart (British Cardiac Society)

Brignole M, Rivasi G.
PMID: 33462120
Heart. 2021 Jun;107(11):864-873. doi: 10.1136/heartjnl-2020-318261. Epub 2021 Jan 18.

This article aims to give advice on how to identify and manage patients with syncope who are at risk of severe outcomes, that is, at risk of trauma, potentially life-threatening episodes or frequent recurrences reducing quality of life. The...

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Brignole M, Rivasi G. New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope. Heart. 2021;107(11):864-873doi: 10.1136/heartjnl-2020-318261.
Brignole, M., & Rivasi, G. (2021). New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope. Heart (British Cardiac Society), 107(11), 864-873. https://doi.org/10.1136/heartjnl-2020-318261
Brignole, Michele, and Rivasi, Giulia. "New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope." Heart (British Cardiac Society) vol. 107,11 (2021): 864-873. doi: https://doi.org/10.1136/heartjnl-2020-318261
Brignole M, Rivasi G. New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope. Heart. 2021 Jun;107(11):864-873. doi: 10.1136/heartjnl-2020-318261. Epub 2021 Jan 18. PMID: 33462120.
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Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay.

Frontiers in cell and developmental biology

Zink A, Conrad J, Telugu NS, Diecke S, Heinz A, Wanker E, Priller J, Prigione A.
PMID: 33224955
Front Cell Dev Biol. 2020 Nov 05;8:590540. doi: 10.3389/fcell.2020.590540. eCollection 2020.

Excessive ethanol exposure can cause mitochondrial and cellular toxicity. In order to discover potential counteracting interventions, it is essential to develop assays capable of capturing the consequences of ethanol exposure in human neurons, and particularly dopaminergic neurons that are...

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Zink A, Conrad J, Telugu NS, et al. Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay. Front Cell Dev Biol. 2020;8:590540doi: 10.3389/fcell.2020.590540.
Zink, A., Conrad, J., Telugu, N. S., Diecke, S., Heinz, A., Wanker, E., Priller, J., & Prigione, A. (2020). Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay. Frontiers in cell and developmental biology, 8590540. https://doi.org/10.3389/fcell.2020.590540
Zink, Annika, et al. "Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay." Frontiers in cell and developmental biology vol. 8 (2020): 590540. doi: https://doi.org/10.3389/fcell.2020.590540
Zink A, Conrad J, Telugu NS, Diecke S, Heinz A, Wanker E, Priller J, Prigione A. Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay. Front Cell Dev Biol. 2020 Nov 05;8:590540. doi: 10.3389/fcell.2020.590540. eCollection 2020. PMID: 33224955; PMCID: PMC7674658.
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Children and parents' perspectives of the impact of the COVID-19 pandemic on Ontario children's physical activity, play, and sport behaviours.

BMC public health

Szpunar M, Vanderloo LM, Bruijns BA, Truelove S, Burke SM, Gilliland J, Irwin JD, Tucker P.
PMID: 34903197
BMC Public Health. 2021 Dec 13;21(1):2271. doi: 10.1186/s12889-021-12344-w.

BACKGROUND: The COVID-19 pandemic and associated public health measures have resulted in the closure of many physical activity-supporting facilities. This study examined Ontario parents' and children's perspectives of COVID-19's impact on children's physical activity behaviours, return to play/sport during...

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Szpunar M, Vanderloo LM, Bruijns BA, et al. Children and parents' perspectives of the impact of the COVID-19 pandemic on Ontario children's physical activity, play, and sport behaviours. BMC Public Health. 2021;21(1):2271doi: 10.1186/s12889-021-12344-w.
Szpunar, M., Vanderloo, L. M., Bruijns, B. A., Truelove, S., Burke, S. M., Gilliland, J., Irwin, J. D., & Tucker, P. (2021). Children and parents' perspectives of the impact of the COVID-19 pandemic on Ontario children's physical activity, play, and sport behaviours. BMC public health, 21(1), 2271. https://doi.org/10.1186/s12889-021-12344-w
Szpunar, Monika, et al. "Children and parents' perspectives of the impact of the COVID-19 pandemic on Ontario children's physical activity, play, and sport behaviours." BMC public health vol. 21,1 (2021): 2271. doi: https://doi.org/10.1186/s12889-021-12344-w
Szpunar M, Vanderloo LM, Bruijns BA, Truelove S, Burke SM, Gilliland J, Irwin JD, Tucker P. Children and parents' perspectives of the impact of the COVID-19 pandemic on Ontario children's physical activity, play, and sport behaviours. BMC Public Health. 2021 Dec 13;21(1):2271. doi: 10.1186/s12889-021-12344-w. PMID: 34903197; PMCID: PMC8666344.
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Coherent beam combining of 61 femtosecond fiber amplifiers.

Optics express

Fsaifes I, Daniault L, Bellanger S, Veinhard M, Bourderionnet J, Larat C, Lallier E, Durand E, Brignon A, Chanteloup JC.
PMID: 32680081
Opt Express. 2020 Jul 06;28(14):20152-20161. doi: 10.1364/OE.394031.

We report on the coherent beam combining of 61 femtosecond fiber chirped-pulse amplifiers in a tiled-aperture configuration along with an interferometric phase measurement technique. Relying on coherent beam recombination in the far field, this technique appears suitable for the...

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Fsaifes I, Daniault L, Bellanger S, et al. Coherent beam combining of 61 femtosecond fiber amplifiers. Opt Express. 2020;28(14):20152-20161doi: 10.1364/OE.394031.
Fsaifes, I., Daniault, L., Bellanger, S., Veinhard, M., Bourderionnet, J., Larat, C., Lallier, E., Durand, E., Brignon, A., & Chanteloup, J. C. (2020). Coherent beam combining of 61 femtosecond fiber amplifiers. Optics express, 28(14), 20152-20161. https://doi.org/10.1364/OE.394031
Fsaifes, Ihsan, et al. "Coherent beam combining of 61 femtosecond fiber amplifiers." Optics express vol. 28,14 (2020): 20152-20161. doi: https://doi.org/10.1364/OE.394031
Fsaifes I, Daniault L, Bellanger S, Veinhard M, Bourderionnet J, Larat C, Lallier E, Durand E, Brignon A, Chanteloup JC. Coherent beam combining of 61 femtosecond fiber amplifiers. Opt Express. 2020 Jul 06;28(14):20152-20161. doi: 10.1364/OE.394031. PMID: 32680081.
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Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment.

Molecular therapy oncolytics

De Lucia M, Cotugno G, Bignone V, Garzia I, Nocchi L, Langone F, Petrovic B, Sasso E, Pepe S, Froechlich G, Gentile C, Zambrano N, Campadelli-Fiume G, Nicosia A, Scarselli E, D'Alise AM.
PMID: 33209980
Mol Ther Oncolytics. 2020 Oct 14;19:253-264. doi: 10.1016/j.omto.2020.10.006. eCollection 2020 Dec 16.

Oncolytic viruses (OVs) are novel anti-tumor agents with the ability to selectively infect and kill tumor cells while sparing normal tissue. Beyond tumor cytolysis, OVs are capable of priming an anti-tumor immune response via lysis and cross-presentation of locally...

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De Lucia M, Cotugno G, Bignone V, et al. Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment. Mol Ther Oncolytics. 2020;19:253-264doi: 10.1016/j.omto.2020.10.006.
De Lucia, M., Cotugno, G., Bignone, V., Garzia, I., Nocchi, L., Langone, F., Petrovic, B., Sasso, E., Pepe, S., Froechlich, G., Gentile, C., Zambrano, N., Campadelli-Fiume, G., Nicosia, A., Scarselli, E., & D'Alise, A. M. (2020). Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment. Molecular therapy oncolytics, 19253-264. https://doi.org/10.1016/j.omto.2020.10.006
De Lucia, Maria, et al. "Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment." Molecular therapy oncolytics vol. 19 (2020): 253-264. doi: https://doi.org/10.1016/j.omto.2020.10.006
De Lucia M, Cotugno G, Bignone V, Garzia I, Nocchi L, Langone F, Petrovic B, Sasso E, Pepe S, Froechlich G, Gentile C, Zambrano N, Campadelli-Fiume G, Nicosia A, Scarselli E, D'Alise AM. Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment. Mol Ther Oncolytics. 2020 Oct 14;19:253-264. doi: 10.1016/j.omto.2020.10.006. eCollection 2020 Dec 16. PMID: 33209980; PMCID: PMC7658578.
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Bone Marrow Environment in Metastatic Neuroblastoma.

Cancers

Brignole C, Pastorino F, Perri P, Amoroso L, Bensa V, Calarco E, Ponzoni M, Corrias MV.
PMID: 34069335
Cancers (Basel). 2021 May 19;13(10). doi: 10.3390/cancers13102467.

The study of the interactions occurring in the BM environment has been facilitated by the peculiar nature of metastatic NB. In fact: (i) metastases are present at diagnosis; (ii) metastases are confined in a very specific tissue, the BM,...

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Brignole C, Pastorino F, Perri P, et al. Bone Marrow Environment in Metastatic Neuroblastoma. Cancers (Basel). 2021;13(10)doi: 10.3390/cancers13102467.
Brignole, C., Pastorino, F., Perri, P., Amoroso, L., Bensa, V., Calarco, E., Ponzoni, M., & Corrias, M. V. (2021). Bone Marrow Environment in Metastatic Neuroblastoma. Cancers, 13(10), . https://doi.org/10.3390/cancers13102467
Brignole, Chiara, et al. "Bone Marrow Environment in Metastatic Neuroblastoma." Cancers vol. 13,10 (2021). doi: https://doi.org/10.3390/cancers13102467
Brignole C, Pastorino F, Perri P, Amoroso L, Bensa V, Calarco E, Ponzoni M, Corrias MV. Bone Marrow Environment in Metastatic Neuroblastoma. Cancers (Basel). 2021 May 19;13(10). doi: 10.3390/cancers13102467. PMID: 34069335; PMCID: PMC8158729.
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Mapping Clinical Barriers and Evidence-Based Implementation Strategies in Low-to-Middle Income Countries (LMICs).

Worldviews on evidence-based nursing

Whitehorn A, Fu L, Porritt K, Lizarondo L, Stephenson M, Marin T, Aye Gyi A, Dell K, Mignone A, Lockwood C.
PMID: 33973346
Worldviews Evid Based Nurs. 2021 Jun;18(3):190-200. doi: 10.1111/wvn.12503. Epub 2021 May 10.

BACKGROUND: Low-to-middle income countries (LMICs) experience a high burden of disease from both non-communicable and communicable diseases. Addressing these public health concerns requires effective implementation strategies and localization of translation of knowledge into practice.AIM: To identify and categorize barriers...

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Whitehorn A, Fu L, Porritt K, et al. Mapping Clinical Barriers and Evidence-Based Implementation Strategies in Low-to-Middle Income Countries (LMICs). Worldviews Evid Based Nurs. 2021;18(3):190-200doi: 10.1111/wvn.12503.
Whitehorn, A., Fu, L., Porritt, K., Lizarondo, L., Stephenson, M., Marin, T., Aye Gyi, A., Dell, K., Mignone, A., & Lockwood, C. (2021). Mapping Clinical Barriers and Evidence-Based Implementation Strategies in Low-to-Middle Income Countries (LMICs). Worldviews on evidence-based nursing, 18(3), 190-200. https://doi.org/10.1111/wvn.12503
Whitehorn, Ashley, et al. "Mapping Clinical Barriers and Evidence-Based Implementation Strategies in Low-to-Middle Income Countries (LMICs)." Worldviews on evidence-based nursing vol. 18,3 (2021): 190-200. doi: https://doi.org/10.1111/wvn.12503
Whitehorn A, Fu L, Porritt K, Lizarondo L, Stephenson M, Marin T, Aye Gyi A, Dell K, Mignone A, Lockwood C. Mapping Clinical Barriers and Evidence-Based Implementation Strategies in Low-to-Middle Income Countries (LMICs). Worldviews Evid Based Nurs. 2021 Jun;18(3):190-200. doi: 10.1111/wvn.12503. Epub 2021 May 10. PMID: 33973346; PMCID: PMC8251858.
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[Eosinophilia and Strongyloides stercoralis infestation: case report].

Le infezioni in medicina

Tassara R, Parodi L, Brignone M, Di Pede E, Scogna M, Minetti F, Bonanni F.
PMID: 12748447
Infez Med. 1999;7(4):253-256.

Authors report about a case of Strongyloides stercoralis infestation. The patient, a 65-year old man, presented with a clinical history of eosinophilia but without symptomatology. Several stool specimen showed the presence of rhabditiform larvae of S. stercoralis and after...

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Tassara R, Parodi L, Brignone M, et al. Eosinofilia e infestazione da Strongyloides stercoralis: caso clinico. [Eosinophilia and Strongyloides stercoralis infestation: case report]. Infez Med. 1999;7(4):253-256
Tassara, R., Parodi, L., Brignone, M., Di Pede, E., Scogna, M., Minetti, F., & Bonanni, F. (1999). Eosinofilia e infestazione da Strongyloides stercoralis: caso clinico. [Eosinophilia and Strongyloides stercoralis infestation: case report]. Le infezioni in medicina, 7(4), 253-256.
Tassara, R., et al. "Eosinofilia e infestazione da Strongyloides stercoralis: caso clinico." [Eosinophilia and Strongyloides stercoralis infestation: case report]. Le infezioni in medicina vol. 7,4 (1999): 253-256.
Tassara R, Parodi L, Brignone M, Di Pede E, Scogna M, Minetti F, Bonanni F. Eosinofilia e infestazione da Strongyloides stercoralis: caso clinico. [Eosinophilia and Strongyloides stercoralis infestation: case report]. Infez Med. 1999;7(4):253-256. Italian. PMID: 12748447.
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Special Issue "Recent Advances in Precision Nanomedicine for Cancer".

Molecules (Basel, Switzerland)

Brignole C, Pastorino F.
PMID: 32927825
Molecules. 2020 Sep 10;25(18). doi: 10.3390/molecules25184148.

Nanomedicine, the application of nanotechnology at the level of one billionth of a millimeter to medicine, has inspired great interest in the last twenty years, leading to the commercialization of successful products both from a clinical and an economic...

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Brignole C, Pastorino F. Special Issue "Recent Advances in Precision Nanomedicine for Cancer". Molecules. 2020;25(18)doi: 10.3390/molecules25184148.
Brignole, C., & Pastorino, F. (2020). Special Issue "Recent Advances in Precision Nanomedicine for Cancer". Molecules (Basel, Switzerland), 25(18), . https://doi.org/10.3390/molecules25184148
Brignole, Chiara, and Pastorino, Fabio. "Special Issue "Recent Advances in Precision Nanomedicine for Cancer"." Molecules (Basel, Switzerland) vol. 25,18 (2020). doi: https://doi.org/10.3390/molecules25184148
Brignole C, Pastorino F. Special Issue "Recent Advances in Precision Nanomedicine for Cancer". Molecules. 2020 Sep 10;25(18). doi: 10.3390/molecules25184148. PMID: 32927825; PMCID: PMC7571208.
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