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Showing 13 to 24 of 168 entries
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Strategic directions for agent-based modeling: avoiding the YAAWN syndrome.

Journal of land use science

O'Sullivan D, Evans T, Manson S, Metcalf S, Ligmann-Zielinska A, Bone C.
PMID: 27158257
J Land Use Sci. 2016;11(2):177-187. doi: 10.1080/1747423X.2015.1030463. Epub 2015 Apr 13.

In this short communication, we examine how agent-based modeling has become common in land change science and is increasingly used to develop case studies for particular times and places. There is a danger that the research community is missing...

Hydroxymethylaniline Photocages for Carboxylic Acids and Alcohols.

The Journal of organic chemistry

Škalamera Đ, Blažek Bregović V, Antol I, Bohne C, Basarić N.
PMID: 29119784
J Org Chem. 2017 Dec 01;82(23):12554-12568. doi: 10.1021/acs.joc.7b02314. Epub 2017 Nov 20.

ortho-, meta- and para-Hydroxymethylaniline methyl ethers 3-5-OMe and acetyl derivatives 3-5-OAc were investigated as potential photocages for alcohols and carboxylic acids, respectively. The measurements of photohydrolysis efficiency showed that the decaging from ortho- and meta-derivatives takes place efficiently in...

Could Dietary Black Soldier Fly Meal Inclusion Affect the Liver and Intestinal Histological Traits and the Oxidative Stress Biomarkers of Siberian Sturgeon (.

Animals : an open access journal from MDPI

Caimi C, Gasco L, Biasato I, Malfatto V, Varello K, Prearo M, Pastorino P, Bona MC, Francese DR, Schiavone A, Elia AC, Dörr AJM, Gai F.
PMID: 31963360
Animals (Basel). 2020 Jan 16;10(1). doi: 10.3390/ani10010155.

The trial investigates if a highly defatted

Mechanical circulatory support in patients with cardiogenic shock not secondary to cardiotomy: a network meta-analysis.

Heart failure reviews

Benenati S, Toma M, Canale C, Vergallo R, Bona RD, Ricci D, Canepa M, Crimi G, Santini F, Ameri P, Porto I.
PMID: 33677732
Heart Fail Rev. 2021 Mar 06; doi: 10.1007/s10741-021-10092-y. Epub 2021 Mar 06.

To compare the efficacy and safety of different mechanical circulatory support (MCS) devices in CS. A total of 24 studies (7 randomized controlled trials-RCTs-and 17 non-RCTs) involving 11,117 patients were entered in a Bayesian network meta-analysis. The primary endpoint...

A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues.

The Journal of biological chemistry

Reilly AM, Yan S, Huang M, Abhyankar SD, Conley JM, Bone RN, Stull ND, Horan DJ, Roh HC, Robling AG, Ericsson AC, Dong XC, Evans-Molina C, Ren H.
PMID: 34801552
J Biol Chem. 2021 Nov 18;298(1):101431. doi: 10.1016/j.jbc.2021.101431. Epub 2021 Nov 18.

Insulin resistance impairs postprandial glucose uptake through glucose transporter type 4 (GLUT4) and is the primary defect preceding type 2 diabetes. We previously generated an insulin-resistant mouse model with human GLUT4 promoter-driven insulin receptor knockout (GIRKO) in the muscle,...

A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues.

The Journal of biological chemistry

Reilly AM, Yan S, Huang M, Abhyankar SD, Conley JM, Bone RN, Stull ND, Horan DJ, Roh HC, Robling AG, Ericsson AC, Dong XC, Evans-Molina C, Ren H.
PMID: 34801552
J Biol Chem. 2021 Nov 18;298(1):101431. doi: 10.1016/j.jbc.2021.101431. Epub 2021 Nov 18.

Insulin resistance impairs postprandial glucose uptake through glucose transporter type 4 (GLUT4) and is the primary defect preceding type 2 diabetes. We previously generated an insulin-resistant mouse model with human GLUT4 promoter-driven insulin receptor knockout (GIRKO) in the muscle,...

Mechanism of a Disassembly-Driven Sensing System Studied by Stopped-Flow Kinetics.

The Journal of organic chemistry

Gallo C, Thomas SS, Selinger AJ, Hof F, Bohne C.
PMID: 34260247
J Org Chem. 2021 Aug 06;86(15):10782-10787. doi: 10.1021/acs.joc.1c00959. Epub 2021 Jul 14.

We carried out steady-state and stopped-flow photophysical measurements to determine the kinetics of a discrete disassembly driven turn-on fluorescent system. On and off rates for both DimerDye1 assembly and nicotine binding were determined. Relative rates for these competing processes...

Intramolecular H-atom abstraction in gamma-azido-butyrophenones: formation of 1,5 ketyl iminyl radicals.

Organic letters

Muthukrishnan S, Sankaranarayanan J, Klima RF, Pace TC, Bohne C, Gudmundsdottir AD.
PMID: 19432450
Org Lett. 2009 Jun 04;11(11):2345-8. doi: 10.1021/ol900754a.

Photolysis of gamma-azidobutyrophenone derivatives yields 1,4 ketyl biradicals via intramolecular H-atom abstraction. The 1,4 ketyl biradicals expel a nitrogen molecule to form 1,5 ketyl iminyl biradicals, which decay by ring closure to form a new carbon-nitrogen bond. The 1,5...

Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: a propensity score-matched analysis.

medRxiv : the preprint server for health sciences

Meizlish ML, Goshua G, Liu Y, Fine R, Amin K, Chang E, DeFilippo N, Keating C, Liu Y, Mankbadi M, McManus D, Wang S, Price C, Bona RD, Chaar CIO, Chun HJ, Pine AB, Rinder HM, Siner J, Neuberg DS, Owusu KA, Lee AI.
PMID: 33469595
medRxiv. 2021 Jan 15; doi: 10.1101/2021.01.12.21249577.

BACKGROUND: Thrombotic complications occur at high rates in hospitalized patients with COVID-19, yet the impact of intensive antithrombotic therapy on mortality is uncertain.RESEARCH QUESTION: How does in-hospital mortality compare with intermediate-versus prophylactic-dose anticoagulation, and separately with in-hospital aspirin versus...

A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues.

The Journal of biological chemistry

Reilly AM, Yan S, Huang M, Abhyankar SD, Conley JM, Bone RN, Stull ND, Horan DJ, Roh HC, Robling AG, Ericsson AC, Dong XC, Evans-Molina C, Ren H.
PMID: 34801552
J Biol Chem. 2021 Nov 18;298(1):101431. doi: 10.1016/j.jbc.2021.101431. Epub 2021 Nov 18.

Insulin resistance impairs postprandial glucose uptake through glucose transporter type 4 (GLUT4) and is the primary defect preceding type 2 diabetes. We previously generated an insulin-resistant mouse model with human GLUT4 promoter-driven insulin receptor knockout (GIRKO) in the muscle,...

Offspring of Obese Dams Exhibit Sex-Differences in Pancreatic Heparan Sulfate Glycosaminoglycans and Islet Insulin Secretion.

Frontiers in endocrinology

Casasnovas J, Damron CL, Jarrell J, Orr KS, Bone RN, Archer-Hartmann S, Azadi P, Kua KL.
PMID: 34108935
Front Endocrinol (Lausanne). 2021 May 24;12:658439. doi: 10.3389/fendo.2021.658439. eCollection 2021.

Offspring of obese mothers suffer higher risks of type 2 diabetes due to increased adiposity and decreased β cell function. To date, the sex-differences in offspring islet insulin secretion during early life has not been evaluated extensively, particularly prior...

Nmp4, a Regulator of Induced Osteoanabolism, Also Influences Insulin Secretion and Sensitivity.

Calcified tissue international

Bidwell J, Tersey SA, Adaway M, Bone RN, Creecy A, Klunk A, Atkinson EG, Wek RC, Robling AG, Wallace JM, Evans-Molina C.
PMID: 34417862
Calcif Tissue Int. 2021 Aug 21; doi: 10.1007/s00223-021-00903-7. Epub 2021 Aug 21.

A bidirectional and complex relationship exists between bone and glycemia. Persons with type 2 diabetes (T2D) are at risk for bone loss and fracture, however, heightened osteoanabolism may ameliorate T2D-induced deficits in glycemia as bone-forming osteoblasts contribute to energy...

Showing 13 to 24 of 168 entries