Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 133 to 144 of 144 entries
Sorted by: Best Match Show Resources per page
Targeting p21.

Cell metabolism

Wang L, Wang B, Gasek NS, Zhou Y, Cohn RL, Martin DE, Zuo W, Flynn WF, Guo C, Jellison ER, Kim T, Langhi Prata LGP, Palmer AK, Li M, Inman CL, Barber LS, Al-Naggar IMA, Zhou Y, Du W, Kshitiz, Kuchel GA, Meves A, Tchkonia T, Kirkland JL, Robson P, Xu M.
PMID: 34986334
Cell Metab. 2022 Jan 04;34(1):186. doi: 10.1016/j.cmet.2021.12.014.

No abstract available.

The Pathogenesis and Clinical Management of Stricturing Crohn Disease.

Inflammatory bowel diseases

Schmoyer CJ, Saidman J, Bohl JL, Bierly CL, Kuemmerle JF, Bickston SJ.
PMID: 33693860
Inflamm Bowel Dis. 2021 Oct 20;27(11):1839-1852. doi: 10.1093/ibd/izab038.

Stricturing of the gastrointestinal tract is a common complication in Crohn disease and is a significant cause of morbidity and mortality among this population. The inflammatory process initiates fibrosis, leading to aberrant wound healing and excess deposition of extracellular...

Targeting p21.

Cell metabolism

Wang L, Wang B, Gasek NS, Zhou Y, Cohn RL, Martin DE, Zuo W, Flynn WF, Guo C, Jellison ER, Kim T, Prata LGPL, Palmer AK, Li M, Inman CL, Barber LS, Al-Naggar IMA, Zhou Y, Du W, Kshitiz, Kuchel GA, Meves A, Tchkonia T, Kirkland JL, Robson P, Xu M.
PMID: 34813734
Cell Metab. 2022 Jan 04;34(1):75-89.e8. doi: 10.1016/j.cmet.2021.11.002. Epub 2021 Nov 22.

Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2 diabetes. Limited mechanism-based strategies exist to alleviate insulin resistance. Here, using single-cell transcriptomics, we identify a small, critically important, but previously...

Copeptin; utility in paediatric patients with hyponatraemia.

Hormone research in paediatrics

Boal RL, Hughes J, Matthews D, Johnstone H, Boot C, Cheetham TD.
PMID: 34814150
Horm Res Paediatr. 2021 Nov 23; doi: 10.1159/000521073. Epub 2021 Nov 23.

Introduction Copeptin concentrations are a useful component of the diagnostic work-up of paediatric patients with polyuria and polydipsia but the value of measuring copeptin in patients with hyponatraemia is less clear. Case Reports We report 5 children with hyponatraemia...

Risk of interstitial lung disease in patients treated for atrial fibrillation with dronedarone versus other antiarrhythmics.

Pharmacoepidemiology and drug safety

Tave A, Goehring E, Desai V, Wu C, Bohn RL, Tamayo SG, Sicignano N, Juhaeri J, Jones JK, Weiss SR.
PMID: 33730412
Pharmacoepidemiol Drug Saf. 2021 Oct;30(10):1353-1359. doi: 10.1002/pds.5233. Epub 2021 May 04.

PURPOSE: To compare risks of interstitial lung disease (ILD) between patients treated with dronedarone versus other antiarrhythmics.METHODS: Parallel retrospective cohort studies were conducted in the United States Department of Defense Military Health System database (DoD) and the HealthCore Integrated...

Targeting p21.

Cell metabolism

Wang L, Wang B, Gasek NS, Zhou Y, Cohn RL, Martin DE, Zuo W, Flynn WF, Guo C, Jellison ER, Kim T, Prata LGPL, Palmer AK, Li M, Inman CL, Barber LS, Al-Naggar IMA, Zhou Y, Kuchel GA, Meves A, Tchkonia T, Kirkland JL, Robson P, Xu M.
PMID: 34813734
Cell Metab. 2021 Nov 19; doi: 10.1016/j.cmet.2021.11.002. Epub 2021 Nov 19.

Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2 diabetes. Limited mechanism-based strategies exist to alleviate insulin resistance. Here, using single-cell transcriptomics, we identify a small, critically important, but previously...

Zika virus infection during pregnancy protects against secondary infection in the absence of CD8.

Virology

Schouest B, Beddingfield BJ, Gilbert MH, Bohm RP, Schiro F, Aye PP, Panganiban AT, Magnani DM, Maness NJ.
PMID: 33865073
Virology. 2021 Jul;559:100-110. doi: 10.1016/j.virol.2021.03.019. Epub 2021 Apr 09.

While T cell immunity is an important component of the immune response to Zika virus (ZIKV) infection generally, the efficacy of these responses during pregnancy remains unknown. Here, we tested the capacity of CD8 lymphocytes to protect from secondary...

Identification of muscle weakness in older adults from normalized upper and lower limbs strength: a cross-sectional study.

BMC sports science, medicine & rehabilitation

Abdalla PP, Bohn L, da Silva LSL, Dos Santos AP, Tasinafo Junior MF, Venturini ACR, Dos Santos Carvalho A, Gomez DM, Mota J, Machado DRL.
PMID: 34922598
BMC Sports Sci Med Rehabil. 2021 Dec 18;13(1):161. doi: 10.1186/s13102-021-00390-1.

BACKGROUND: To propose cut-off points for older adults' weakness for upper and lower limbs muscle strength normalized by body size with the ratio standard/muscle quality and allometric scaling.METHODS: Ninety-four community-dwelling older adults (69.1% women) were assessed for 49 body-size...

Associations Between Depressive Symptoms and Physical Activity Intensity in an Older Adult Population During COVID-19 Lockdown.

Frontiers in psychology

Lage A, Carrapatoso S, Sampaio de Queiroz Neto E, Gomes S, Soares-Miranda L, Bohn L.
PMID: 34163399
Front Psychol. 2021 Jun 07;12:644106. doi: 10.3389/fpsyg.2021.644106. eCollection 2021.

INTRODUCTION: The COVID-19 pandemic led to the implementation of physical-social distancing measures-including self-isolation, home confinement, and quarantine around the world, with psychological consequences such as depression. Older adults are especially likely to develop depressive symptomatology. This study aims to...

Does universal newborn hearing screening impact the timing of deafness treatment?.

Jornal de pediatria

Faistauer M, Silva AL, Dominguez DOR, Bohn R, Félix TM, Costa SSD, Rosito LPS.
PMID: 34166624
J Pediatr (Rio J). 2021 Jun 21; doi: 10.1016/j.jped.2021.04.008. Epub 2021 Jun 21.

OBJECTIVE: To evaluate the impact of the Universal Neonatal Hearing Screening (UNHS) on the age at diagnosis, beginning of treatment, and first cochlear implant surgery.METHODS: A retrospective cohort study with children up to 12 years old with bilateral hearing...

Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates.

bioRxiv : the preprint server for biology

S Arunachalam P, Walls AC, Golden N, Atyeo C, Fischinger S, Li C, Aye P, Navarro MJ, Lai L, Edara VV, Roltgen K, Rogers K, Shirreff L, Ferrell DE, Wrenn S, Pettie D, Kraft JC, Miranda MC, Kepl E, Sydeman C, Brunette N, Murphy M, Fiala B, Carter L, White AG, Trisal M, Hsieh CL, Russell-Lodrigue K, Monjure C, Dufour J, Doyle-Meyer L, Bohm RB, Maness NJ, Roy C, Plante JA, Plante KS, Zhu A, Gorman MJ, Shin S, Shen X, Fontenot J, Gupta S, O Hagan DT, Most RV, Rappuoli R, Coffman RL, Novack D, McLellan JS, Subramaniam S, Montefiori D, Boyd SD, Flynn JL, Alter G, Villinger F, Kleanthous H, Rappaport J, Suthar M, King NP, Veesler D, Pulendran B.
PMID: 33594366
bioRxiv. 2021 Feb 11; doi: 10.1101/2021.02.10.430696.

The development of a portfolio of SARS-CoV-2 vaccines to vaccinate the global population remains an urgent public health imperative. Here, we demonstrate the capacity of a subunit vaccine under clinical development, comprising the SARS-CoV-2 Spike protein receptor-binding domain displayed...

The Implementation and Effect of Weekend Pharmacy-Driven Antimicrobial Stewardship Services at a Large Academic Medical Center.

Journal of pharmacy practice

Bohn BC, Neuner EA, Athans V, Rivard KR, Riffle AR, Richter SS, Fraser TG, Gordon SM.
PMID: 33648376
J Pharm Pract. 2021 Mar 02;897190021997008. doi: 10.1177/0897190021997008. Epub 2021 Mar 02.

BACKGROUND: In September 2018, pharmacy antimicrobial stewardship (AMS) services were expanded to include weekends at this academic medical center. Activities performed by AMS pharmacists on the weekends include blood culture rapid diagnostic (RDT) review, antiretroviral therapy (ART) review, prospective...

Showing 133 to 144 of 144 entries