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Implementation of an electronic patient-reported measure of barriers to antiretroviral therapy adherence with the Opal patient portal: Protocol for a mixed method type 3 hybrid pilot study at a large Montreal HIV clinic.

PloS one

Engler K, Vicente S, Ma Y, Hijal T, Cox J, Ahmed S, Klein M, Achiche S, Pant Pai N, de Pokomandy A, Lacombe K, Lebouché B.
PMID: 34969046
PLoS One. 2021 Dec 30;16(12):e0261006. doi: 10.1371/journal.pone.0261006. eCollection 2021.

BACKGROUND: Adherence to antiretroviral therapy (ART) remains problematic. Regular monitoring of its barriers is clinically recommended, however, patient-provider communication around adherence is often inadequate. Our team thus decided to develop a new electronically administered patient-reported outcome measure (PROM) of...

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Engler K, Vicente S, Ma Y, et al. Implementation of an electronic patient-reported measure of barriers to antiretroviral therapy adherence with the Opal patient portal: Protocol for a mixed method type 3 hybrid pilot study at a large Montreal HIV clinic. PLoS One. 2021;16(12):e0261006doi: 10.1371/journal.pone.0261006.
Engler, K., Vicente, S., Ma, Y., Hijal, T., Cox, J., Ahmed, S., Klein, M., Achiche, S., Pant Pai, N., de Pokomandy, A., Lacombe, K., & Lebouché, B. (2021). Implementation of an electronic patient-reported measure of barriers to antiretroviral therapy adherence with the Opal patient portal: Protocol for a mixed method type 3 hybrid pilot study at a large Montreal HIV clinic. PloS one, 16(12), e0261006. https://doi.org/10.1371/journal.pone.0261006
Engler, Kim, et al. "Implementation of an electronic patient-reported measure of barriers to antiretroviral therapy adherence with the Opal patient portal: Protocol for a mixed method type 3 hybrid pilot study at a large Montreal HIV clinic." PloS one vol. 16,12 (2021): e0261006. doi: https://doi.org/10.1371/journal.pone.0261006
Engler K, Vicente S, Ma Y, Hijal T, Cox J, Ahmed S, Klein M, Achiche S, Pant Pai N, de Pokomandy A, Lacombe K, Lebouché B. Implementation of an electronic patient-reported measure of barriers to antiretroviral therapy adherence with the Opal patient portal: Protocol for a mixed method type 3 hybrid pilot study at a large Montreal HIV clinic. PLoS One. 2021 Dec 30;16(12):e0261006. doi: 10.1371/journal.pone.0261006. eCollection 2021. PMID: 34969046; PMCID: PMC8717992.
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Linking anaerobic gut bacteria and cardiovascular disease.

Nature microbiology

Coker J, Zaramela LS, Zengler K.
PMID: 34949825
Nat Microbiol. 2022 Jan;7(1):14-15. doi: 10.1038/s41564-021-01009-4.

No abstract available.

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Coker J, Zaramela LS, Zengler K. Linking anaerobic gut bacteria and cardiovascular disease. Nat Microbiol. 2022;7(1):14-15doi: 10.1038/s41564-021-01009-4.
Coker, J., Zaramela, L. S., & Zengler, K. (2022). Linking anaerobic gut bacteria and cardiovascular disease. Nature microbiology, 7(1), 14-15. https://doi.org/10.1038/s41564-021-01009-4
Coker, Joanna, et al. "Linking anaerobic gut bacteria and cardiovascular disease." Nature microbiology vol. 7,1 (2022): 14-15. doi: https://doi.org/10.1038/s41564-021-01009-4
Coker J, Zaramela LS, Zengler K. Linking anaerobic gut bacteria and cardiovascular disease. Nat Microbiol. 2022 Jan;7(1):14-15. doi: 10.1038/s41564-021-01009-4. PMID: 34949825.
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Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension.

Journal of the American Heart Association

Fengler K, Reimann P, Rommel KP, Kresoja KP, Blazek S, Unterhuber M, Besler C, von Roeder M, Böhm M, Desch S, Thiele H, Lurz P.
PMID: 34713718
J Am Heart Assoc. 2021 Nov 02;10(21):e022429. doi: 10.1161/JAHA.121.022429. Epub 2021 Oct 29.

Background Recent trial results support the efficacy of renal sympathetic denervation in lowering blood pressure (BP). While BP reduction in general is associated with a clinically meaningful reduction in cardiovascular events and mortality, such a relationship has not been...

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Fengler K, Reimann P, Rommel KP, et al. Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension. J Am Heart Assoc. 2021;10(21):e022429doi: 10.1161/JAHA.121.022429.
Fengler, K., Reimann, P., Rommel, K. P., Kresoja, K. P., Blazek, S., Unterhuber, M., Besler, C., von Roeder, M., Böhm, M., Desch, S., Thiele, H., & Lurz, P. (2021). Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension. Journal of the American Heart Association, 10(21), e022429. https://doi.org/10.1161/JAHA.121.022429
Fengler, Karl, et al. "Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension." Journal of the American Heart Association vol. 10,21 (2021): e022429. doi: https://doi.org/10.1161/JAHA.121.022429
Fengler K, Reimann P, Rommel KP, Kresoja KP, Blazek S, Unterhuber M, Besler C, von Roeder M, Böhm M, Desch S, Thiele H, Lurz P. Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension. J Am Heart Assoc. 2021 Nov 02;10(21):e022429. doi: 10.1161/JAHA.121.022429. Epub 2021 Oct 29. PMID: 34713718; PMCID: PMC8751833.
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Increased reengagement of out-of-care HIV patients using lost & found, a clinic-based intervention.

AIDS (London, England)

Linthwaite B, Kronfli N, Marbaniang I, Ruppenthal L, Lessard D, Engler K, Lebouché B, Cox J.
PMID: 34897240
AIDS. 2021 Dec 13; doi: 10.1097/QAD.0000000000003147. Epub 2021 Dec 13.

BACKGROUND: Negative health outcomes associated with being out of HIV care (OOC) warrant reengagement strategies. We aimed to assess effectiveness of Lost & Found (L&F), a clinic-based intervention to identify and reengage OOC patients.METHODS: Developed and delivered using implementation...

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Linthwaite B, Kronfli N, Marbaniang I, et al. Increased reengagement of out-of-care HIV patients using lost & found, a clinic-based intervention. AIDS. 2021;doi: 10.1097/QAD.0000000000003147.
Linthwaite, B., Kronfli, N., Marbaniang, I., Ruppenthal, L., Lessard, D., Engler, K., Lebouché, B., Cox, J. (2021). Increased reengagement of out-of-care HIV patients using lost & found, a clinic-based intervention. AIDS (London, England), . https://doi.org/10.1097/QAD.0000000000003147
Linthwaite, Blake, et al. "Increased reengagement of out-of-care HIV patients using lost & found, a clinic-based intervention." AIDS (London, England) vol. (2021). doi: https://doi.org/10.1097/QAD.0000000000003147
Linthwaite B, Kronfli N, Marbaniang I, Ruppenthal L, Lessard D, Engler K, Lebouché B, Cox J. Increased reengagement of out-of-care HIV patients using lost & found, a clinic-based intervention. AIDS. 2021 Dec 13; doi: 10.1097/QAD.0000000000003147. Epub 2021 Dec 13. PMID: 34897240.
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Advances in metabolic modeling of oleaginous microalgae.

Biotechnology for biofuels

Tibocha-Bonilla JD, Zuñiga C, Godoy-Silva RD, Zengler K.
PMID: 30202436
Biotechnol Biofuels. 2018 Sep 05;11:241. doi: 10.1186/s13068-018-1244-3. eCollection 2018.

Production of biofuels and bioenergy precursors by phototrophic microorganisms, such as microalgae and cyanobacteria, is a promising alternative to conventional fuels obtained from non-renewable resources. Several species of microalgae have been investigated as potential candidates for the production of...

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Tibocha-Bonilla JD, Zuñiga C, Godoy-Silva RD, et al. Advances in metabolic modeling of oleaginous microalgae. Biotechnol Biofuels. 2018;11:241doi: 10.1186/s13068-018-1244-3.
Tibocha-Bonilla, J. D., Zuñiga, C., Godoy-Silva, R. D., & Zengler, K. (2018). Advances in metabolic modeling of oleaginous microalgae. Biotechnology for biofuels, 11241. https://doi.org/10.1186/s13068-018-1244-3
Tibocha-Bonilla, Juan D, et al. "Advances in metabolic modeling of oleaginous microalgae." Biotechnology for biofuels vol. 11 (2018): 241. doi: https://doi.org/10.1186/s13068-018-1244-3
Tibocha-Bonilla JD, Zuñiga C, Godoy-Silva RD, Zengler K. Advances in metabolic modeling of oleaginous microalgae. Biotechnol Biofuels. 2018 Sep 05;11:241. doi: 10.1186/s13068-018-1244-3. eCollection 2018. PMID: 30202436; PMCID: PMC6124020.
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Genomic and Transcriptomic Evidence Supports Methane Metabolism in .

mSystems

Liu YF, Chen J, Zaramela LS, Wang LY, Mbadinga SM, Hou ZW, Wu XL, Gu JD, Zengler K, Mu BZ.
PMID: 32184369
mSystems. 2020 Mar 17;5(2). doi: 10.1128/mSystems.00651-19.

Euryarchaeal lineages have been believed to have a methanogenic last common ancestor. However, members of euryarchaeal

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Liu YF, Chen J, Zaramela LS, et al. Genomic and Transcriptomic Evidence Supports Methane Metabolism in . mSystems. 2020;5(2)doi: 10.1128/mSystems.00651-19.
Liu, Y. F., Chen, J., Zaramela, L. S., Wang, L. Y., Mbadinga, S. M., Hou, Z. W., Wu, X. L., Gu, J. D., Zengler, K., & Mu, B. Z. (2020). Genomic and Transcriptomic Evidence Supports Methane Metabolism in . mSystems, 5(2), . https://doi.org/10.1128/mSystems.00651-19
Liu, Yi-Fan, et al. "Genomic and Transcriptomic Evidence Supports Methane Metabolism in ." mSystems vol. 5,2 (2020). doi: https://doi.org/10.1128/mSystems.00651-19
Liu YF, Chen J, Zaramela LS, Wang LY, Mbadinga SM, Hou ZW, Wu XL, Gu JD, Zengler K, Mu BZ. Genomic and Transcriptomic Evidence Supports Methane Metabolism in . mSystems. 2020 Mar 17;5(2). doi: 10.1128/mSystems.00651-19. PMID: 32184369; PMCID: PMC7380581.
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A Novel Sparse Compositional Technique Reveals Microbial Perturbations.

mSystems

Martino C, Morton JT, Marotz CA, Thompson LR, Tripathi A, Knight R, Zengler K.
PMID: 30801021
mSystems. 2019 Feb 12;4(1). doi: 10.1128/mSystems.00016-19. eCollection 2019.

The central aims of many host or environmental microbiome studies are to elucidate factors associated with microbial community compositions and to relate microbial features to outcomes. However, these aims are often complicated by difficulties stemming from high-dimensionality, non-normality, sparsity,...

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Martino C, Morton JT, Marotz CA, et al. A Novel Sparse Compositional Technique Reveals Microbial Perturbations. mSystems. 2019;4(1)doi: 10.1128/mSystems.00016-19.
Martino, C., Morton, J. T., Marotz, C. A., Thompson, L. R., Tripathi, A., Knight, R., & Zengler, K. (2019). A Novel Sparse Compositional Technique Reveals Microbial Perturbations. mSystems, 4(1), . https://doi.org/10.1128/mSystems.00016-19
Martino, Cameron, et al. "A Novel Sparse Compositional Technique Reveals Microbial Perturbations." mSystems vol. 4,1 (2019). doi: https://doi.org/10.1128/mSystems.00016-19
Martino C, Morton JT, Marotz CA, Thompson LR, Tripathi A, Knight R, Zengler K. A Novel Sparse Compositional Technique Reveals Microbial Perturbations. mSystems. 2019 Feb 12;4(1). doi: 10.1128/mSystems.00016-19. eCollection 2019. PMID: 30801021; PMCID: PMC6372836.
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Efficient Synergistic Single-Cell Genome Assembly.

Frontiers in bioengineering and biotechnology

Movahedi NS, Embree M, Nagarajan H, Zengler K, Chitsaz H.
PMID: 27243002
Front Bioeng Biotechnol. 2016 May 23;4:42. doi: 10.3389/fbioe.2016.00042. eCollection 2016.

As the vast majority of all microbes are unculturable, single-cell sequencing has become a significant method to gain insight into microbial physiology. Single-cell sequencing methods, currently powered by multiple displacement genome amplification (MDA), have passed important milestones such as...

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Movahedi NS, Embree M, Nagarajan H, et al. Efficient Synergistic Single-Cell Genome Assembly. Front Bioeng Biotechnol. 2016;4:42doi: 10.3389/fbioe.2016.00042.
Movahedi, N. S., Embree, M., Nagarajan, H., Zengler, K., & Chitsaz, H. (2016). Efficient Synergistic Single-Cell Genome Assembly. Frontiers in bioengineering and biotechnology, 442. https://doi.org/10.3389/fbioe.2016.00042
Movahedi, Narjes S, et al. "Efficient Synergistic Single-Cell Genome Assembly." Frontiers in bioengineering and biotechnology vol. 4 (2016): 42. doi: https://doi.org/10.3389/fbioe.2016.00042
Movahedi NS, Embree M, Nagarajan H, Zengler K, Chitsaz H. Efficient Synergistic Single-Cell Genome Assembly. Front Bioeng Biotechnol. 2016 May 23;4:42. doi: 10.3389/fbioe.2016.00042. eCollection 2016. PMID: 27243002; PMCID: PMC4876485.
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Reported Distribution of Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus in the United States, 1995-2016 (Diptera: Culicidae).

Journal of medical entomology

Hahn MB, Eisen RJ, Eisen L, Boegler KA, Moore CG, McAllister J, Savage HM, Mutebi JP.
PMID: 27282817
J Med Entomol. 2016 Sep 01;53(5):1169-1175. doi: 10.1093/jme/tjw072.

Aedes (Stegomyia) aegypti (L.) and Aedes (Stegomyia) albopictus (Skuse) transmit arboviruses that are increasing threats to human health in the Americas, particularly dengue, chikungunya, and Zika viruses. Epidemics of the associated arboviral diseases have been limited to South and...

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Hahn MB, Eisen RJ, Eisen L, et al. Reported Distribution of Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus in the United States, 1995-2016 (Diptera: Culicidae). J Med Entomol. 2016;53(5):1169-1175doi: 10.1093/jme/tjw072.
Hahn, M. B., Eisen, R. J., Eisen, L., Boegler, K. A., Moore, C. G., McAllister, J., Savage, H. M., & Mutebi, J. P. (2016). Reported Distribution of Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus in the United States, 1995-2016 (Diptera: Culicidae). Journal of medical entomology, 53(5), 1169-1175. https://doi.org/10.1093/jme/tjw072
Hahn, Micah B, et al. "Reported Distribution of Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus in the United States, 1995-2016 (Diptera: Culicidae)." Journal of medical entomology vol. 53,5 (2016): 1169-1175. doi: https://doi.org/10.1093/jme/tjw072
Hahn MB, Eisen RJ, Eisen L, Boegler KA, Moore CG, McAllister J, Savage HM, Mutebi JP. Reported Distribution of Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus in the United States, 1995-2016 (Diptera: Culicidae). J Med Entomol. 2016 Sep 01;53(5):1169-1175. doi: 10.1093/jme/tjw072. PMID: 27282817.
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Iatrogenic Atrial Septal Defects Following Transcatheter Mitral Valve Repair and Implications of Interventional Closure.

JACC. Cardiovascular interventions

Lurz P, Unterhuber M, Rommel KP, Kresoja KP, Kister T, Besler C, Fengler K, Sandri M, Daehnert I, Thiele H, Blazek S, von Roeder M.
PMID: 34949392
JACC Cardiovasc Interv. 2021 Dec 27;14(24):2685-2694. doi: 10.1016/j.jcin.2021.09.023.

OBJECTIVES: The authors investigated whether iatrogenic atrial septal defect (iASD) closure post-transcatheter mitral valve edge-to-edge repair (TMVR) is superior to conservative therapy (CT) and whether outcomes (death/heart failure [HF] hospitalization) differ between patients with and without an iASD post-TMVR.BACKGROUND:...

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Lurz P, Unterhuber M, Rommel KP, et al. Iatrogenic Atrial Septal Defects Following Transcatheter Mitral Valve Repair and Implications of Interventional Closure. JACC Cardiovasc Interv. 2021;14(24):2685-2694doi: 10.1016/j.jcin.2021.09.023.
Lurz, P., Unterhuber, M., Rommel, K. P., Kresoja, K. P., Kister, T., Besler, C., Fengler, K., Sandri, M., Daehnert, I., Thiele, H., Blazek, S., & von Roeder, M. (2021). Iatrogenic Atrial Septal Defects Following Transcatheter Mitral Valve Repair and Implications of Interventional Closure. JACC. Cardiovascular interventions, 14(24), 2685-2694. https://doi.org/10.1016/j.jcin.2021.09.023
Lurz, Philipp, et al. "Iatrogenic Atrial Septal Defects Following Transcatheter Mitral Valve Repair and Implications of Interventional Closure." JACC. Cardiovascular interventions vol. 14,24 (2021): 2685-2694. doi: https://doi.org/10.1016/j.jcin.2021.09.023
Lurz P, Unterhuber M, Rommel KP, Kresoja KP, Kister T, Besler C, Fengler K, Sandri M, Daehnert I, Thiele H, Blazek S, von Roeder M. Iatrogenic Atrial Septal Defects Following Transcatheter Mitral Valve Repair and Implications of Interventional Closure. JACC Cardiovasc Interv. 2021 Dec 27;14(24):2685-2694. doi: 10.1016/j.jcin.2021.09.023. PMID: 34949392.
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Targeted BRCA1/2 population screening among Ashkenazi Jewish individuals using a web-enabled medical model: An observational cohort study.

Genetics in medicine : official journal of the American College of Medical Genetics

Morgan KM, Hamilton JG, Symecko H, Kamara D, Jenkins C, Lester J, Spielman K, Pace LE, Gabriel C, Levin JD, Tejada PR, Braswell A, Marcell V, Wildman T, Devolder B, Baum RC, Block JN, Fesko Y, Boehler K, Howell V, Heitler J, Robson ME, Nathanson KL, Tung N, Karlan BY, Domchek SM, Garber JE, Offit K.
PMID: 34906490
Genet Med. 2021 Dec 03; doi: 10.1016/j.gim.2021.10.016. Epub 2021 Dec 03.

PURPOSE: This study aimed to evaluate uptake and follow-up using internet-assisted population genetic testing (GT) for BRCA1/2 Ashkenazi Jewish founder pathogenic variants (AJPVs).METHODS: Across 4 cities in the United States, from December 2017 to March 2020, individuals aged ≄25...

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Morgan KM, Hamilton JG, Symecko H, et al. Targeted BRCA1/2 population screening among Ashkenazi Jewish individuals using a web-enabled medical model: An observational cohort study. Genet Med. 2021;doi: 10.1016/j.gim.2021.10.016.
Morgan, K. M., Hamilton, J. G., Symecko, H., Kamara, D., Jenkins, C., Lester, J., Spielman, K., Pace, L. E., Gabriel, C., Levin, J. D., Tejada, P. R., Braswell, A., Marcell, V., Wildman, T., Devolder, B., Baum, R. C., Block, J. N., Fesko, Y., Boehler, K., Howell, V., Heitler, J., Robson, M. E., Nathanson, K. L., Tung, N., Karlan, B. Y., Domchek, S. M., Garber, J. E., & Offit, K. (2021). Targeted BRCA1/2 population screening among Ashkenazi Jewish individuals using a web-enabled medical model: An observational cohort study. Genetics in medicine : official journal of the American College of Medical Genetics, . https://doi.org/10.1016/j.gim.2021.10.016
Morgan, Kelly M, et al. "Targeted BRCA1/2 population screening among Ashkenazi Jewish individuals using a web-enabled medical model: An observational cohort study." Genetics in medicine : official journal of the American College of Medical Genetics vol. (2021). doi: https://doi.org/10.1016/j.gim.2021.10.016
Morgan KM, Hamilton JG, Symecko H, Kamara D, Jenkins C, Lester J, Spielman K, Pace LE, Gabriel C, Levin JD, Tejada PR, Braswell A, Marcell V, Wildman T, Devolder B, Baum RC, Block JN, Fesko Y, Boehler K, Howell V, Heitler J, Robson ME, Nathanson KL, Tung N, Karlan BY, Domchek SM, Garber JE, Offit K. Targeted BRCA1/2 population screening among Ashkenazi Jewish individuals using a web-enabled medical model: An observational cohort study. Genet Med. 2021 Dec 03; doi: 10.1016/j.gim.2021.10.016. Epub 2021 Dec 03. PMID: 34906490.
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Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension.

Journal of the American Heart Association

Fengler K, Reimann P, Rommel KP, Kresoja KP, Blazek S, Unterhuber M, Besler C, von Roeder M, Böhm M, Desch S, Thiele H, Lurz P.
PMID: 34713718
J Am Heart Assoc. 2021 Nov 02;10(21):e022429. doi: 10.1161/JAHA.121.022429. Epub 2021 Oct 29.

Background Recent trial results support the efficacy of renal sympathetic denervation in lowering blood pressure (BP). While BP reduction in general is associated with a clinically meaningful reduction in cardiovascular events and mortality, such a relationship has not been...

Cite
Fengler K, Reimann P, Rommel KP, et al. Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension. J Am Heart Assoc. 2021;10(21):e022429doi: 10.1161/JAHA.121.022429.
Fengler, K., Reimann, P., Rommel, K. P., Kresoja, K. P., Blazek, S., Unterhuber, M., Besler, C., von Roeder, M., Böhm, M., Desch, S., Thiele, H., & Lurz, P. (2021). Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension. Journal of the American Heart Association, 10(21), e022429. https://doi.org/10.1161/JAHA.121.022429
Fengler, Karl, et al. "Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension." Journal of the American Heart Association vol. 10,21 (2021): e022429. doi: https://doi.org/10.1161/JAHA.121.022429
Fengler K, Reimann P, Rommel KP, Kresoja KP, Blazek S, Unterhuber M, Besler C, von Roeder M, Böhm M, Desch S, Thiele H, Lurz P. Comparison of Long-Term Outcomes for Responders Versus Non-Responders Following Renal Denervation in Resistant Hypertension. J Am Heart Assoc. 2021 Nov 02;10(21):e022429. doi: 10.1161/JAHA.121.022429. Epub 2021 Oct 29. PMID: 34713718.
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