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Showing 85 to 90 of 90 entries
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Polygenic risk for obesity and its interaction with lifestyle and sociodemographic factors in European children and adolescents.

International journal of obesity (2005)

Hüls A, Wright MN, Bogl LH, Kaprio J, Lissner L, Molnár D, Moreno LA, De Henauw S, Siani A, Veidebaum T, Ahrens W, Pigeot I, Foraita R.
PMID: 33753884
Int J Obes (Lond). 2021 Jun;45(6):1321-1330. doi: 10.1038/s41366-021-00795-5. Epub 2021 Mar 22.

BACKGROUND: Childhood obesity is a complex multifaceted condition, which is influenced by genetics, environmental factors, and their interaction. However, these interactions have mainly been studied in twin studies and evidence from population-based cohorts is limited. Here, we analyze the...

Ketone body 3-hydroxybutyrate as a biomarker of aggression.

Scientific reports

Whipp AM, Vuoksimaa E, Korhonen T, Pool R, But A, Ligthart L, Hagenbeek FA, Bartels M, Bogl LH, Pulkkinen L, Rose RJ, Boomsma DI, Kaprio J.
PMID: 33712630
Sci Rep. 2021 Mar 12;11(1):5813. doi: 10.1038/s41598-021-84635-6.

Human aggression is a complex behaviour, the biological underpinnings of which remain poorly known. To gain insights into aggression biology, we studied relationships with aggression of 11 low-molecular-weight metabolites (amino acids, ketone bodies), processed using

GPX7 Facilitates BMSCs Osteoblastogenesis via ER Stress and mTOR Pathway.

Journal of cellular and molecular medicine

Hu X, Li B, Wu F, Liu X, Liu M, Wang C, Shi Y, Ye L.
PMID: 34626080
J Cell Mol Med. 2021 Nov;25(22):10454-10465. doi: 10.1111/jcmm.16974. Epub 2021 Oct 09.

Emerging evidence indicates extensive oxidative stress is a consequence of obesity which impairs bone formation. Glutathione peroxidase 7 (GPX7) is a conserved endoplasmic reticulum (ER) retention protein, lacking of which causes accumulation of reactive oxygen species (ROS) and promotes...

Prognostic value of circulating calprotectin levels on the clinical course of COVID-19 differs between serum, heparin, EDTA and citrate sample types.

Clinica chimica acta; international journal of clinical chemistry

Nevejan L, Strypens T, Van Nieuwenhove M, Boel A, Cattoir L, Meeus P, Bossuyt X, De Neve N, Van Hoovels L.
PMID: 34919937
Clin Chim Acta. 2021 Dec 14; doi: 10.1016/j.cca.2021.12.011. Epub 2021 Dec 14.

INTRODUCTION: During the recent SARS-CoV-2 pandemic, circulating calprotectin (cCLP) gained interest as biomarker to predict the severity of COVID-19. We aimed to investigate the prognostic value of cCLP measured in serum, heparin, EDTA and citrate plasma.MATERIALS AND METHODS: COVID-19...

Prognostic value of circulating calprotectin levels on the clinical course of COVID-19 differs between serum, heparin, EDTA and citrate sample types.

Clinica chimica acta; international journal of clinical chemistry

Nevejan L, Strypens T, Van Nieuwenhove M, Boel A, Cattoir L, Meeus P, Bossuyt X, De Neve N, Van Hoovels L.
PMID: 34919937
Clin Chim Acta. 2021 Dec 14;525:54-61. doi: 10.1016/j.cca.2021.12.011. Epub 2021 Dec 14.

INTRODUCTION: During the recent SARS-CoV-2 pandemic, circulating calprotectin (cCLP) gained interest as biomarker to predict the severity of COVID-19. We aimed to investigate the prognostic value of cCLP measured in serum, heparin, EDTA and citrate plasma.MATERIALS AND METHODS: COVID-19...

Targeting reactive oxygen species in stem cells for bone therapy.

Drug discovery today

Li X, Li B, Shi Y, Wang C, Ye L.
PMID: 33684524
Drug Discov Today. 2021 May;26(5):1226-1244. doi: 10.1016/j.drudis.2021.03.002. Epub 2021 Mar 05.

Reactive oxygen species (ROS) have emerged as key players in regulating the fate and function of stem cells from both non-hematopoietic and hematopoietic lineages in bone marrow, and thus affect the osteoblastogenesis-osteoclastogenesis balance and bone homeostasis. Accumulating evidence has...

Showing 85 to 90 of 90 entries