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Showing 277 to 288 of 289 entries
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Evaluation of Optogenetic Electrophysiology Tools in Human Stem Cell-Derived Cardiomyocytes.

Frontiers in physiology

Björk S, Ojala EA, Nordström T, Ahola A, Liljeström M, Hyttinen J, Kankuri E, Mervaala E.
PMID: 29163220
Front Physiol. 2017 Nov 02;8:884. doi: 10.3389/fphys.2017.00884. eCollection 2017.

Current cardiac drug safety assessments focus on hERG channel block and QT prolongation for evaluating arrhythmic risks, whereas the optogenetic approach focuses on the action potential (AP) waveform generated by a monolayer of human cardiomyocytes beating synchronously, thus assessing...

Hierarchical Dehydrogenation Reactions on a Copper Surface.

Journal of the American Chemical Society

Li Q, Yang B, Björk J, Zhong Q, Ju H, Zhang J, Cao N, Shi Z, Zhang H, Ebeling D, Schirmeisen A, Zhu J, Chi L.
PMID: 29543446
J Am Chem Soc. 2018 May 16;140(19):6076-6082. doi: 10.1021/jacs.7b12278. Epub 2018 Mar 27.

Hierarchical control of chemical reactions is being considered as one of the most ambitious and challenging topics in modern organic chemistry. In this study, we have realized the one-by-one scission of the X-H bonds (X = N and C)...

C-H activation of light alkanes on MXenes predicted by hydrogen affinity.

Physical chemistry chemical physics : PCCP

Niu K, Chi L, Rosen J, Björk J.
PMID: 32789324
Phys Chem Chem Phys. 2020 Sep 07;22(33):18622-18630. doi: 10.1039/d0cp02471f. Epub 2020 Aug 13.

C-H activation of light alkanes is one of the most important reactions for a plethora of applications but requires catalysts to operate at feasible conditions. MXenes, a new group of two-dimensional materials, have shown great promise as heterogeneous catalysts...

A Meta-Epidemiological Appraisal of the Effects of Interdisciplinary Multimodal Pain Therapy Dosing for Chronic Low Back Pain.

Journal of clinical medicine

Dragioti E, Björk M, Larsson B, Gerdle B.
PMID: 31216757
J Clin Med. 2019 Jun 18;8(6). doi: 10.3390/jcm8060871.

Using a meta-analysis, meta-regression, and a meta-epidemiological approach, we conducted a systematic review to examine the influence of interdisciplinary multimodal pain therapy (IMPT) dosage on pain, disability, return to work, quality of life, depression, and anxiety in published randomised...

Late follow-up of genital and ophthalmologic chronic graft-versus-host disease in females after allogeneic stem cell transplantation.

Acta obstetricia et gynecologica Scandinavica

Smith Knutsson E, Nicklasson M, Björk Y, Stenberg K, Sundfeldt K, Brune M.
PMID: 34962288
Acta Obstet Gynecol Scand. 2021 Dec 28; doi: 10.1111/aogs.14308. Epub 2021 Dec 28.

INTRODUCTION: Genital chronic graft-versus-host disease (cGvHD) is a common late effect after allogeneic stem cell transplantation. In a previous cross-sectional study, prevalence, signs and symptoms of genital and extra-genital cGvHD were accounted for in a cohort of 42 women....

Integration of whole genome sequencing into a healthcare setting: high diagnostic rates across multiple clinical entities in 3219 rare disease patients.

Genome medicine

Stranneheim H, Lagerstedt-Robinson K, Magnusson M, Kvarnung M, Nilsson D, Lesko N, Engvall M, Anderlid BM, Arnell H, Johansson CB, Barbaro M, Björck E, Bruhn H, Eisfeldt J, Freyer C, Grigelioniene G, Gustavsson P, Hammarsjö A, Hellström-Pigg M, Iwarsson E, Jemt A, Laaksonen M, Enoksson SL, Malmgren H, Naess K, Nordenskjöld M, Oscarson M, Pettersson M, Rasi C, Rosenbaum A, Sahlin E, Sardh E, Stödberg T, Tesi B, Tham E, Thonberg H, Töhönen V, von Döbeln U, Vassiliou D, Vonlanthen S, Wikström AC, Wincent J, Winqvist O, Wredenberg A, Ygberg S, Zetterström RH, Marits P, Soller MJ, Nordgren A, Wirta V, Lindstrand A, Wedell A.
PMID: 33726816
Genome Med. 2021 Mar 17;13(1):40. doi: 10.1186/s13073-021-00855-5.

BACKGROUND: We report the findings from 4437 individuals (3219 patients and 1218 relatives) who have been analyzed by whole genome sequencing (WGS) at the Genomic Medicine Center Karolinska-Rare Diseases (GMCK-RD) since mid-2015. GMCK-RD represents a long-term collaborative initiative between...

Senior authors' reply to the comment by Rivano-Fischer and Stålnacke.

European journal of pain (London, England)

Gerdle B, Björk M, Dahlström Ö, Vixner L, Äng BO.
PMID: 34845780
Eur J Pain. 2021 Nov 30; doi: 10.1002/ejp.1891. Epub 2021 Nov 30.

No abstract available.

Characterization of Laminins in Healthy Human Aortic Valves and a Modified Decellularized Rat Scaffold.

BioResearch open access

Granath C, Noren H, Björck H, Simon N, Olesen K, Rodin S, Grinnemo KH, Österholm C.
PMID: 33376633
Biores Open Access. 2020 Dec 07;9(1):269-278. doi: 10.1089/biores.2020.0018. eCollection 2020.

Aortic valve stenosis is one of the most common cardiovascular diseases in western countries and can only be treated by replacement with a prosthetic valve. Tissue engineering is an emerging and promising treatment option, but in-depth knowledge about the...

Erratum to: Interferon activation status underlies higher antibody response to viral antigens in patients with systemic lupus erythematosus receiving no or light treatment.

Rheumatology (Oxford, England)

Björk A, Da Silva Rodrigues R, Richardsdotter Andersson E, Ramírez Sepúlveda JI, Mofors J, Kvarnström M, Oke V, Svenungsson E, Gunnarsson I, Wahren-Herlenius M.
PMID: 33377143
Rheumatology (Oxford). 2021 Mar 02;60(3):1575. doi: 10.1093/rheumatology/keaa867.

No abstract available.

Inter-annual variation in prevalence of Borrelia burgdorferi sensu stricto and Anaplasma phagocytophilum in host-seeking Ixodes scapularis (Acari: Ixodidae) at long-term surveillance sites in the upper midwestern United States: Implications for public health practice.

Ticks and tick-borne diseases

Foster E, Burtis J, Sidge JL, Tsao JI, Bjork J, Liu G, Neitzel DF, Lee X, Paskewitz S, Caporale D, Eisen RJ.
PMID: 34929604
Ticks Tick Borne Dis. 2021 Dec 05;13(2):101886. doi: 10.1016/j.ttbdis.2021.101886. Epub 2021 Dec 05.

The geographic range of the blacklegged tick, Ixodes scapularis, and its associated human pathogens have expanded substantially over the past 20 years putting an increasing number of persons at risk for tick-borne diseases, particularly in the upper midwestern and...

Mitochondrial activities play a pivotal role in regulating cell cycle in response to doxorubicin.

Cell cycle (Georgetown, Tex.)

Dornfeld K, Bjork J, Folkert G, Skildum A, Wallace KB.
PMID: 33978554
Cell Cycle. 2021 Jun;20(11):1067-1079. doi: 10.1080/15384101.2021.1919839. Epub 2021 May 12.

Doxorubicin induces both DNA damage and metabolic interference. How these effects interact to modulate cellular toxicity is not completely understood but important given the widespread use of doxorubicin in cancer treatment. This study tests the hypothesis that cell cycle...

Effect of an Educational Program on Healthcare Professionals' Readiness to Support Patients with Asthma, Allergies, and Chronic Obstructive Lung Disease for Improved Medication Adherence.

Nursing research and practice

Axelsson M, Björk B, Berg U, Persson K.
PMID: 33194229
Nurs Res Pract. 2020 Oct 27;2020:1585067. doi: 10.1155/2020/1585067. eCollection 2020.

PURPOSE: The aim of this study was to strengthen the healthcare professionals' readiness to support patients who have asthma, an allergy, and COPD for better medication adherence.METHODS: The design was an educational intervention in a study population (RESULTS: The...

Showing 277 to 288 of 289 entries