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Showing 13 to 24 of 49 entries
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Characterization of the efficacies of osimertinib and nazartinib against cells expressing clinically relevant epidermal growth factor receptor mutations.

Oncotarget

Masuzawa K, Yasuda H, Hamamoto J, Nukaga S, Hirano T, Kawada I, Naoki K, Soejima K, Betsuyaku T.
PMID: 29285266
Oncotarget. 2017 Nov 06;8(62):105479-105491. doi: 10.18632/oncotarget.22297. eCollection 2017 Dec 01.

Third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) were developed to overcome

Thermofield transfer-matrix method and its applications to quantum spin systems.

Physical review. B, Condensed matter

Betsuyaku H, Suzuki M.
PMID: 9939840
Phys Rev B Condens Matter. 1986 Aug 01;34(3):1829-1834. doi: 10.1103/physrevb.34.1829.

No abstract available.

Mechanisms to Suppress ILC2-induced Airway Inflammation.

Annals of the American Thoracic Society

Kabata H, Moro K, Koyasu S, Fukunaga K, Asano K, Betsuyaku T.
PMID: 27027961
Ann Am Thorac Soc. 2016 Mar;13:S95. doi: 10.1513/AnnalsATS.201508-557MG.

Epithelial cell-derived cytokines such as IL-33 and IL-25 activate group 2 innate lymphoid cells (ILC2s), which are known to be important sources of type 2 cytokines such as IL-5 and IL-13 in a variety of asthma mouse models. Recently,...

Levels of Soluble Receptor for Advanced Glycation End Products in Bronchoalveolar Lavage Fluid in Patients with Various Inflammatory Lung Diseases.

Clinical medicine insights. Circulatory, respiratory and pulmonary medicine

Kamo T, Tasaka S, Tokuda Y, Suzuki S, Asakura T, Yagi K, Namkoong H, Ishii M, Hasegawa N, Betsuyaku T.
PMID: 27147899
Clin Med Insights Circ Respir Pulm Med. 2016 Apr 28;9:147-54. doi: 10.4137/CCRPM.S23326. eCollection 2015.

Receptor for advanced glycation end products (RAGE) is a multiligand receptor of S100/calgranulins, high-mobility group box 1, and others, and it is associated with the pathogenesis of various inflammatory and circulatory diseases. The soluble form of RAGE (sRAGE) is...

Alectinib as a treatment option following recovery from crizotinib-induced interstitial lung disease in patients with anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer.

Molecular and clinical oncology

Nukaga S, Naoki K, Kamo T, Masuzawa K, Yasuda H, Soejima K, Betsuyaku T.
PMID: 27284449
Mol Clin Oncol. 2016 Jun;4(6):1085-1087. doi: 10.3892/mco.2016.838. Epub 2016 Mar 30.

Crizotinib is a tyrosine kinase inhibitor that displays antitumor activity against anaplastic lymphoma kinase (

Root-specific CLE3 expression is required for WRKY33 activation in Arabidopsis shoots.

Plant molecular biology

Ma D, Endo S, Betsuyaku E, Fujiwara T, Betsuyaku S, Fukuda H.
PMID: 35038066
Plant Mol Biol. 2022 Jan 17; doi: 10.1007/s11103-021-01234-9. Epub 2022 Jan 17.

KEY MESSAGE: This study focused on the role of CLE1-7 peptides as defense mediators, and showed that root-expressed CLE3 functions as a systemic signal to regulate defense-related gene expression in shoots. In the natural environment, plants employ diverse signaling...

Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer.

Cancer research

Ishioka K, Yasuda H, Hamamoto J, Terai H, Emoto K, Kim TJ, Hirose S, Kamatani T, Mimaki S, Arai D, Ohgino K, Tani T, Masuzawa K, Manabe T, Shinozaki T, Mitsuishi A, Ebisudani T, Fukushima T, Ozaki M, Ikemura S, Kawada I, Naoki K, Nakamura M, Ohtsuka T, Asamura H, Tsuchihara K, Hayashi Y, Hegab AE, Kobayashi SS, Kohno T, Watanabe H, Ornitz DM, Betsuyaku T, Soejima K, Fukunaga K.
PMID: 34083250
Cancer Res. 2021 Jul 15;81(14):3916-3929. doi: 10.1158/0008-5472.CAN-20-4048. Epub 2021 Jun 03.

Transdifferentiation of lung adenocarcinoma to small cell lung cancer (SCLC) has been reported in a subset of lung cancer cases that bear EGFR mutations. Several studies have reported the prerequisite role of

Risk factors for poor adherence to inhaled corticosteroid therapy in patients with moderate to severe asthma.

Asian Pacific journal of allergy and immunology

Masaki K, Miyata J, Kamatani T, Tanosaki T, Mochimaru T, Kabata H, Suzuki Y, Asano K, Betsuyaku T, Fukunaga K.
PMID: 32563226
Asian Pac J Allergy Immunol. 2020 Jun 21; doi: 10.12932/AP-311219-0731. Epub 2020 Jun 21.

BACKGROUND: Poor adherence to inhaled corticosteroid (ICS) therapy is a common reason for worsened asthma control.OBJECTIVE: We investigated the characteristics of patients with moderate to severe asthma who showed poor adherence to therapy, to identify the barriers for optimal...

Factors associated with improvements in subjective symptoms of obstructive sleep apnea syndrome after continuous positive airway pressure therapy.

Sleep & breathing = Schlaf & Atmung

Otsuka K, Fukunaga K, WakakoYamasawa, Haraguchi M, Tani T, Shirahama R, Betsuyaku T.
PMID: 31280400
Sleep Breath. 2020 Jun;24(2):491-498. doi: 10.1007/s11325-019-01877-5. Epub 2019 Jul 06.

PURPOSE: Continuous positive airway pressure (CPAP) therapy improves subjective symptoms in obstructive sleep apnea syndrome (OSAS) patients; however, factors predicting symptom improvement post-CPAP therapy and the CPAP duration necessary for improving subjective symptoms are unclear. This study aimed to...

The Impact of Smoking on Pulmonary Metastasis in Colorectal Cancer.

OncoTargets and therapy

Makino A, Tsuruta M, Okabayashi K, Ishida T, Shigeta K, Seishima R, Ikebata A, Koishikawa K, Hasegawa H, Shimoda M, Fukunaga K, Betsuyaku T, Kitagawa Y.
PMID: 33061444
Onco Targets Ther. 2020 Sep 30;13:9623-9629. doi: 10.2147/OTT.S263250. eCollection 2020.

INTRODUCTION: Recently, clinical studies have revealed that smoking can contribute to the poor prognosis of colorectal cancer (CRC) and, additionally, can be a risk factor for pulmonary metastasis of CRC. However, there has been no basic research regarding the...

Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer.

Cancer research

Ishioka K, Yasuda H, Hamamoto J, Terai H, Emoto K, Kim TJ, Hirose S, Kamatani T, Mimaki S, Arai D, Ohgino K, Tani T, Masuzawa K, Manabe T, Shinozaki T, Mitsuishi A, Ebisudani T, Fukushima T, Ozaki M, Ikemura S, Kawada I, Naoki K, Nakamura M, Ohtsuka T, Asamura H, Tsuchihara K, Hayashi Y, Hegab AE, Kobayashi SS, Kohno T, Watanabe H, Ornitz DM, Betsuyaku T, Soejima K, Fukunaga K.
PMID: 34083250
Cancer Res. 2021 Jul 15;81(14):3916-3929. doi: 10.1158/0008-5472.CAN-20-4048. Epub 2021 Jun 03.

Transdifferentiation of lung adenocarcinoma to small cell lung cancer (SCLC) has been reported in a subset of lung cancer cases that bear EGFR mutations. Several studies have reported the prerequisite role of

Reliability of measurement using Image J for reach distance and movement angles in the functional reach test.

Journal of physical therapy science

Suzuki T, Hashisdate H, Fujisawa Y, Yatsunami M, Ota T, Shimizu N, Betsuyaku T.
PMID: 33642684
J Phys Ther Sci. 2021 Feb;33(2):112-117. doi: 10.1589/jpts.33.112. Epub 2021 Feb 13.

[Purpose] The purpose of this study was to examine the test-retest reliability and minimal detectable change (MDC) of reach distance and movement angle analyses using Image J. [Participants and Methods] Thirty-eight healthy young males performed the functional reach test...

Showing 13 to 24 of 49 entries