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Showing 25 to 36 of 175 entries
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Palindromic Rheumatism Frequently Precedes Early Rheumatoid Arthritis: Results From an Incident Cohort.

ACR open rheumatology

Ellingwood L, Schieir O, Valois MF, Bartlett SJ, Bessette L, Boire G, Hazlewood G, Hitchon C, Keystone EC, Tin D, Thorne C, Bykerk VP, Pope JE.
PMID: 31872182
ACR Open Rheumatol. 2019 Oct 21;1(10):614-619. doi: 10.1002/acr2.11086. eCollection 2019 Dec.

BACKGROUND: This multicenter incident cohort aimed to characterize how often early rheumatoid arthritis (ERA) patients self-report episodic joint inflammation (palindromic rheumatism) preceding ERA diagnosis and which characteristics differentiate these patients from those without prior episodic symptoms.METHODS: Data were from...

Local immune checkpoint blockade therapy by an adenovirus encoding a novel PD-L1 inhibitory peptide inhibits the growth of colon carcinoma in immunocompetent mice.

Translational oncology

Ishiguro S, Upreti D, Bassette M, Singam ERA, Thakkar R, Loyd M, Inui M, Comer J, Tamura M.
PMID: 34990908
Transl Oncol. 2022 Feb;16:101337. doi: 10.1016/j.tranon.2021.101337. Epub 2022 Jan 03.

A novel peptide that interferes with the PD-1/PD-L1 immune checkpoint pathway, termed PD-L1 inhibitory peptide 3 (PD-L1ip3), was computationally designed, experimentally validated for its specific binding to PD-L1, and evaluated for its antitumor effects in cell culture and in...

Accuracy of Identifying Diagnosis of Moderate to Severe Chronic Kidney Disease in Administrative Claims Data.

Pharmacoepidemiology and drug safety

Paik JM, Patorno E, Zhuo M, Bessette LG, York C, Gautam N, Kim DH, Kim SC.
PMID: 34908211
Pharmacoepidemiol Drug Saf. 2021 Dec 15; doi: 10.1002/pds.5398. Epub 2021 Dec 15.

BACKGROUND: Prior validation studies of claims-based definitions of chronic kidney disease (CKD) using ICD-9 codes reported overall low sensitivity, high specificity, and variable but reasonable PPV. No studies to date have evaluated the accuracy of ICD-10 codes to identify...

A CASE REPORT OF CHRONIC ENDOPHTHALMITIS SECONDARY TO AQUAMICROBIUM TERRAE.

Retinal cases & brief reports

Venkat AG, Abraham JR, Bessette A, Karthik N, Baynes K, Lowder CY, Srivastava S.
PMID: 32349062
Retin Cases Brief Rep. 2020 Apr 28; doi: 10.1097/ICB.0000000000001003. Epub 2020 Apr 28.

PURPOSE: Chronic postoperative endophthalmitis is a known complication of cataract surgery. Here, we report a case of chronic endophthalmitis following uncomplicated cataract surgery secondary to the atypical bacterium Aquamicrobium terrae.METHODS: Retrospective case report of a single patient with endophthalmitis...

Effects of calcitriol on oxidative burst, phagocytic function, and leukocyte cytokine production in shelter dogs.

Canine medicine and genetics

Jaffey JA, Bessette M, Tao Z, Bradley-Siemens N, Thompson M.
PMID: 32924019
Canine Med Genet. 2020 Aug 14;7:11. doi: 10.1186/s40575-020-00090-y. eCollection 2020.

BACKGROUND: The active metabolite of vitamin D, calcitriol, has been shown across many different species to augment innate immune responses and dampen aberrant proinflammatory cytokine production. Community acquired infections are common in shelters and consume limited shelter resources, impact...

Co-creating Simulated Cultural Communication Scenarios with Indigenous Animators: An Evaluation of Innovative Clinical Cultural Safety Curriculum.

Journal of medical education and curricular development

Maar M, Bessette N, McGregor L, Lovelace A, Reade M.
PMID: 33403243
J Med Educ Curric Dev. 2020 Dec 15;7:2382120520980488. doi: 10.1177/2382120520980488. eCollection 2020.

BACKGROUND: Building on partnerships with Indigenous communities and with the support of the Northern Ontario School of Medicine, faculty created groundbreaking, authentic cultural immersion curriculum designed to foster culturally safe interpersonal skills and cultural understanding. However, structural barriers to...

Association of Sodium-Glucose Cotransporter-2 Inhibitors With Fracture Risk in Older Adults With Type 2 Diabetes.

JAMA network open

Zhuo M, Hawley CE, Paik JM, Bessette LG, Wexler DJ, Kim DH, Tong AY, Kim SC, Patorno E.
PMID: 34705014
JAMA Netw Open. 2021 Oct 01;4(10):e2130762. doi: 10.1001/jamanetworkopen.2021.30762.

IMPORTANCE: Whether sodium-glucose cotransporter-2 inhibitors (SGLT-2i) are associated with an increased risk of fractures in older adults with type 2 diabetes (T2D) outside of clinical trials remains unknown.OBJECTIVE: To examine the association of incident fracture among older adults with...

Multivariate Imaging Genetics Study of MRI Gray Matter Volume and SNPs Reveals Biological Pathways Correlated with Brain Structural Differences in Attention Deficit Hyperactivity Disorder.

Frontiers in psychiatry

Khadka S, Pearlson GD, Calhoun VD, Liu J, Gelernter J, Bessette KL, Stevens MC.
PMID: 27504100
Front Psychiatry. 2016 Jul 25;7:128. doi: 10.3389/fpsyt.2016.00128. eCollection 2016.

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder affecting children, adolescents, and adults. Its etiology is not well understood, but it is increasingly believed to result from diverse pathophysiologies that affect the structure and function of...

Design and synthesis of a new class of nonmacrocyclic alkali metal host compounds.

Organic letters

McGarvey GJ, Stepanian MW, Bressette AR, Sabat M.
PMID: 11082007
Org Lett. 2000 Nov 02;2(22):3453-6. doi: 10.1021/ol006468o.

A new class of nonmacrocyclic metal ion hosts has been examined that features a polyspirocyclic framework that offers a 1,3,5-triaxial presentation of ligating centers. These compounds are easily synthesized and exploit stereoelectronic influences to preorganize the metal ion binding...

[The dentist and financial planning. I].

Le Journal dentaire du Quebec

Bessette C.
PMID: 1076375
J Dent Que. 1975 Oct;12(10):14.

No abstract available.

Fungal Planet description sheets: 868-950.

Persoonia

Crous PW, Carnegie AJ, Wingfield MJ, Sharma R, Mughini G, Noordeloos ME, Santini A, Shouche YS, Bezerra JDP, Dima B, Guarnaccia V, Imrefi I, Jurjević Ž, Knapp DG, Kovács GM, Magistà D, Perrone G, Rämä T, Rebriev YA, Shivas RG, Singh SM, Souza-Motta CM, Thangavel R, Adhapure NN, Alexandrova AV, Alfenas AC, Alfenas RF, Alvarado P, Alves AL, Andrade DA, Andrade JP, Barbosa RN, Barili A, Barnes CW, Baseia IG, Bellanger JM, Berlanas C, Bessette AE, Bessette AR, Biketova AY, Bomfim FS, Brandrud TE, Bransgrove K, Brito ACQ, Cano-Lira JF, Cantillo T, Cavalcanti AD, Cheewangkoon R, Chikowski RS, Conforto C, Cordeiro TRL, Craine JD, Cruz R, Damm U, de Oliveira RJV, de Souza JT, de Souza HG, Dearnaley JDW, Dimitrov RA, Dovana F, Erhard A, Esteve-Raventós F, Félix CR, Ferisin G, Fernandes RA, Ferreira RJ, Ferro LO, Figueiredo CN, Frank JL, Freire KTLS, García D, Gené J, Gêsiorska A, Gibertoni TB, Gondra RAG, Gouliamova DE, Gramaje D, Guard F, Gusmão LFP, Haitook S, Hirooka Y, Houbraken J, Hubka V, Inamdar A, Iturriaga T, Iturrieta-González I, Jadan M, Jiang N, Justo A, Kachalkin AV, Kapitonov VI, Karadelev M, Karakehian J, Kasuya T, Kautmanová I, Kruse J, Kušan I, Kuznetsova TA, Landell MF, Larsson KH, Lee HB, Lima DX, Lira CRS, Machado AR, Madrid H, Magalhães OMC, Majerova H, Malysheva EF, Mapperson RR, Marbach PAS, Martín MP, Martín-Sanz A, Matočec N, McTaggart AR, Mello JF, Melo RFR, Mešić A, Michereff SJ, Miller AN, Minoshima A, Molinero-Ruiz L, Morozova OV, Mosoh D, Nabe M, Naik R, Nara K, Nascimento SS, Neves RP, Olariaga I, Oliveira RL, Oliveira TGL, Ono T, Ordoñez ME, Ottoni AM, Paiva LM, Pancorbo F, Pant B, Pawłowska J, Peterson SW, Raudabaugh DB, Rodríguez-Andrade E, Rubio E, Rusevska K, Santiago ALCMA, Santos ACS, Santos C, Sazanova NA, Shah S, Sharma J, Silva BDB, Siquier JL, Sonawane MS, Stchigel AM, Svetasheva T, Tamakeaw N, Telleria MT, Tiago PV, Tian CM, Tkalčec Z, Tomashevskaya MA, Truong HH, Vecherskii MV, Visagie CM, Vizzini A, Yilmaz N, Zmitrovich IV, Zvyagina EA, Boekhout T, Kehlet T, Læssøe T, Groenewald JZ.
PMID: 31551622
Persoonia. 2019 Jun;42:291-473. doi: 10.3767/persoonia.2019.42.11. Epub 2019 Jul 19.

Novel species of fungi described in this study include those from various countries as follows:

Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma.

Oncotarget

Veeranki OL, Tong Z, Dokey R, Mejia A, Zhang J, Qiao Y, Singh PK, Katkhuda R, Mino B, Tailor R, Canales JR, Bassett R, Ajani J, Wu JY, Kopetz S, Blum M, Hofstetter W, Tetzlaff M, Krishnan S, Lin SH, Maru D.
PMID: 31384397
Oncotarget. 2019 Jul 23;10(45):4703-4718. doi: 10.18632/oncotarget.27095. eCollection 2019 Jul 23.

Cyclin-dependent kinase 9 (CDK9) transcriptionally regulates several proteins and cellular pathways central to radiation induced tissue injury. We investigated a role of BAY1143572, a new highly specific CDK9 inhibitor, as a sensitizer to radiation in esophageal adenocarcinoma.

Showing 25 to 36 of 175 entries