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Showing 3553 to 3560 of 3560 entries
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Effect of simulated gastro-duodenal digestion on the allergenic reactivity of beta-lactoglobulin.

Clinical and translational allergy

Bossios A, Theodoropoulou M, Mondoulet L, Rigby NM, Papadopoulos NG, Bernard H, Adel-Patient K, Wal JM, Mills CE, Papageorgiou P.
PMID: 22410304
Clin Transl Allergy. 2011 Aug 09;1(1):6. doi: 10.1186/2045-7022-1-6.

BACKGROUND: Cow's milk (CM) allergy affects about 2% of infants. The allergenicity of dietary proteins, including those from CM, has been related to their digestibility although the generality of the link and its causality remains to be demonstrated. In...

Transtibial Anterior Cruciate Ligament Reconstruction: Tips for a Successful Anatomic Reconstruction.

Arthroscopy techniques

Manderle BJ, Beletsky A, Gorodischer T, Chahla J, Cancienne JM, Vadhera AS, Trasolini N, Williams BT, Gursoy S, Bach BR, Verma NN.
PMID: 35004161
Arthrosc Tech. 2021 Nov 29;10(12):e2783-e2788. doi: 10.1016/j.eats.2021.08.025. eCollection 2021 Dec.

Anterior cruciate ligament (ACL) reconstruction is one of the most commonly performed orthopaedic sports procedures. Two main techniques are used for accomplishing an ACL reconstruction: transtibial and anteromedial portal techniques. The transtibial technique has been criticized for its inability...

Peptidomics of enteroendocrine cells and characterisation of potential effects of a novel preprogastrin derived-peptide on glucose tolerance in lean mice.

Peptides

Galvin SG, Larraufie P, Kay RG, Pitt H, Bernard E, McGavigan AK, Brant H, Hood J, Sheldrake L, Conder S, Atherton-Kemp D, Lu VB, O'Flaherty EAA, Roberts GP, Ämmälä C, Jermutus L, Baker D, Gribble FM, Reimann F.
PMID: 33744371
Peptides. 2021 Jun;140:170532. doi: 10.1016/j.peptides.2021.170532. Epub 2021 Mar 17.

OBJECTIVES: To analyse the peptidomics of mouse enteroendocrine cells (EECs) and human gastrointestinal (GI) tissue and identify novel gut derived peptides.METHODS: High resolution nano-flow liquid chromatography mass spectrometry (LC-MS/MS) was performed on (i) flow-cytometry purified NeuroD1 positive cells from...

Effects of initial invasive vs. initial conservative treatment strategies on recurrent and total cardiovascular events in the ISCHEMIA trial.

European heart journal

Lopez-Sendon JL, Cyr DD, Mark DB, Bangalore S, Huang Z, White HD, Alexander KP, Li J, Nair RG, Demkow M, Peteiro J, Wander GS, Demchenko EA, Gamma R, Gadkari M, Poh KK, Nageh T, Stone PH, Keltai M, Sidhu M, Newman JD, Boden WE, Reynolds HR, Chaitman BR, Hochman JS, Maron DJ, O'Brien SM.
PMID: 34514494
Eur Heart J. 2022 Jan 13;43(2):148-149. doi: 10.1093/eurheartj/ehab509.

AIMS: The International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial prespecified an analysis to determine whether accounting for recurrent cardiovascular events in addition to first events modified understanding of the treatment effects.METHODS AND RESULTS:...

Widespread introgression across a phylogeny of 155 Drosophila genomes.

Current biology : CB

Suvorov A, Kim BY, Wang J, Armstrong EE, Peede D, D'Agostino ERR, Price DK, Waddell P, Lang M, Courtier-Orgogozo V, David JR, Petrov D, Matute DR, Schrider DR, Comeault AA.
PMID: 34788634
Curr Biol. 2022 Jan 10;32(1):111-123.e5. doi: 10.1016/j.cub.2021.10.052. Epub 2021 Nov 16.

Genome-scale sequence data have invigorated the study of hybridization and introgression, particularly in animals. However, outside of a few notable cases, we lack systematic tests for introgression at a larger phylogenetic scale across entire clades. Here, we leverage 155...

Radiopharmaceutical Validation for Clinical Use.

Frontiers in oncology

Kunos CA, Howells R, Chauhan A, Myint ZW, Bernard ME, El Khouli R, Capala J.
PMID: 33747951
Front Oncol. 2021 Mar 03;11:630827. doi: 10.3389/fonc.2021.630827. eCollection 2021.

Radiopharmaceuticals are reemerging as attractive anticancer agents, but there are no universally adopted guidelines or standardized procedures for evaluating agent validity before early-phase trial implementation. To validate a radiopharmaceutical, it is desirous for the radiopharmaceutical to be specific, selective,...

Tumor density is associated with response to endobronchial ultrasound-guided transbronchial needle injection of cisplatin.

Journal of thoracic disease

Kinsey CM, San José Estépar R, Bates JHT, Cole BF, Washko G, Jantz M, Mehta H.
PMID: 33145055
J Thorac Dis. 2020 Sep;12(9):4825-4832. doi: 10.21037/jtd-20-674.

BACKGROUND: Endobronchial ultrasound-guided transbronchial needle injection of cisplatin (EBUS-TBNI cisplatin) is a therapeutic option for patients with recurrent lung cancer. However, the tumor characteristics that influence the distribution of the agent following intratumoral delivery remain largely unknown.METHODS: We performed...

Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects.

Proceedings of the National Academy of Sciences of the United States of America

Kandasamy R, Hillhouse TM, Livingston KE, Kochan KE, Meurice C, Eans SO, Li MH, White AD, Roques BP, McLaughlin JP, Ingram SL, Burford NT, Alt A, Traynor JR.
PMID: 33846240
Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). doi: 10.1073/pnas.2000017118.

Positive allosteric modulators (PAMs) of the mu-opioid receptor (MOR) have been hypothesized as potentially safer analgesics than traditional opioid drugs. This is based on the idea that PAMs will promote the action of endogenous opioid peptides while preserving their...

Showing 3553 to 3560 of 3560 entries