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Showing 385 to 393 of 393 entries
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Spatially organized multicellular immune hubs in human colorectal cancer.

Cell

Pelka K, Hofree M, Chen JH, Sarkizova S, Pirl JD, Jorgji V, Bejnood A, Dionne D, Ge WH, Xu KH, Chao SX, Zollinger DR, Lieb DJ, Reeves JW, Fuhrman CA, Hoang ML, Delorey T, Nguyen LT, Waldman J, Klapholz M, Wakiro I, Cohen O, Albers J, Smillie CS, Cuoco MS, Wu J, Su MJ, Yeung J, Vijaykumar B, Magnuson AM, Asinovski N, Moll T, Goder-Reiser MN, Applebaum AS, Brais LK, DelloStritto LK, Denning SL, Phillips ST, Hill EK, Meehan JK, Frederick DT, Sharova T, Kanodia A, Todres EZ, Jané-Valbuena J, Biton M, Izar B, Lambden CD, Clancy TE, Bleday R, Melnitchouk N, Irani J, Kunitake H, Berger DL, Srivastava A, Hornick JL, Ogino S, Rotem A, Vigneau S, Johnson BE, Corcoran RB, Sharpe AH, Kuchroo VK, Ng K, Giannakis M, Nieman LT, Boland GM, Aguirre AJ, Anderson AC, Rozenblatt-Rosen O, Regev A, Hacohen N.
PMID: 34450029
Cell. 2021 Sep 02;184(18):4734-4752.e20. doi: 10.1016/j.cell.2021.08.003. Epub 2021 Aug 26.

Immune responses to cancer are highly variable, with mismatch repair-deficient (MMRd) tumors exhibiting more anti-tumor immunity than mismatch repair-proficient (MMRp) tumors. To understand the rules governing these varied responses, we transcriptionally profiled 371,223 cells from colorectal tumors and adjacent...

Analysis of amino acids, hydroxy acids, and amines in CR chondrites.

Meteoritics & planetary science

Aponte JC, Elsila JE, Hein JE, Dworkin JP, Glavin DP, McLain HL, Parker ET, Cao T, Berger EL, Burton AS.
PMID: 33536738
Meteorit Planet Sci. 2020 Nov;55(11):2422-2439. doi: 10.1111/maps.13586. Epub 2020 Dec 16.

The abundances, relative distributions, and enantiomeric and isotopic compositions of amines, amino acids, and hydroxy acids in Miller Range (MIL) 090001 and MIL 090657 meteorites were determined. Chiral distributions and isotopic compositions confirmed that most of the compounds detected...

The Impact of Surgical Center Volume on Reoperation Risk after Mid Urethral Sling.

The Journal of urology

Berger AA, Tan-Kim J, Menefee SA.
PMID: 34288737
J Urol. 2021 Dec;206(6):1454-1460. doi: 10.1097/JU.0000000000002140. Epub 2021 Jul 21.

PURPOSE: We sought to determine whether a center's surgical volume affects patient reoperation rates after mid urethral sling (MUS) surgery.MATERIALS AND METHODS: We performed a retrospective cohort study evaluating a large managed care organization from 2005 to 2016. The...

Sleep difficulties, incident dementia and all-cause mortality among older adults across 8 years: Findings from the National Health and Aging Trends Study.

Journal of sleep research

Robbins R, Weaver MD, Barger LK, Wang W, Quan SF, Czeisler CA.
PMID: 34080234
J Sleep Res. 2021 Dec;30(6):e13395. doi: 10.1111/jsr.13395. Epub 2021 Jun 02.

Sleep difficulties have been implicated in the development and progression of dementia and in all-cause mortality. This study examines the relationship between sleep difficulties, incident dementia and all-cause mortality over 8 years of follow-up among a nationally representative sample...

Beware of Neurotoxins in Common Plants: Water Hemlock Poisoning Presenting as Convulsive Status Epilepticus.

Pediatric neurology

Arsenova R, Prager C, Becker LL, Scholtis S, Methling M, Kaindl AM.
PMID: 34954473
Pediatr Neurol. 2021 Nov 29;127:39-40. doi: 10.1016/j.pediatrneurol.2021.11.011. Epub 2021 Nov 29.

BACKGROUND: Pediatric status epilepticus occurs in about 44/100.000 children per year with an unknown cause in about a third of patients. One cause can be the ingestion of plants containing toxins that target the central nervous system. Here we...

Guiding principles for determining work shift duration and addressing the effects of work shift duration on performance, safety, and health: guidance from the American Academy of Sleep Medicine and the Sleep Research Society.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Gurubhagavatula I, Barger LK, Barnes CM, Basner M, Boivin DB, Dawson D, Drake CL, Flynn-Evans EE, Mysliwiec V, Patterson PD, Reid KJ, Samuels C, Shattuck NL, Kazmi U, Carandang G, Heald JL, Van Dongen HPA.
PMID: 34666885
J Clin Sleep Med. 2021 Nov 01;17(11):2283-2306. doi: 10.5664/jcsm.9512.

CITATION: Risks associated with fatigue that accumulates during work shifts have historically been managed through working time arrangements that specify fixed maximum durations of work shifts and minimum durations of time off. By themselves, such arrangements are not sufficient...

Obstructive Jaundice Secondary to Peribiliary Cyst Within the Common Hepatic Duct.

The American surgeon

Gartland RM, Landino SM, Liang NE, Day CJ, Berger DL.
PMID: 33283523
Am Surg. 2020 Dec 07;3134820973359. doi: 10.1177/0003134820973359. Epub 2020 Dec 07.

No abstract available.

Adverse Effects of Recreational and Medical Cannabis.

Psychopharmacology bulletin

Urits I, Charipova K, Gress K, Li N, Berger AA, Cornett EM, Kassem H, Ngo AL, Kaye AD, Viswanath O.
PMID: 33897066
Psychopharmacol Bull. 2021 Jan 12;51(1):94-109.

PURPOSE OF REVIEW: This comprehensive review discusses the adverse effects known today about marijuana, for either medical or recreational use. It reviews the role of cannabis in the treatment of chronic pain, cognitive and neurological adverse effects, special cases...

MRI correlates of cognitive improvement after home-based EEG neurofeedback training in patients with multiple sclerosis: a pilot study.

Journal of neurology

Pinter D, Kober SE, Fruhwirth V, Berger L, Damulina A, Khalil M, Neuper C, Wood G, Enzinger C.
PMID: 33786666
J Neurol. 2021 Oct;268(10):3808-3816. doi: 10.1007/s00415-021-10530-9. Epub 2021 Mar 30.

OBJECTIVE: Neurofeedback training may improve cognitive function in patients with neurological disorders. However, the underlying cerebral mechanisms of such improvements are poorly understood. Therefore, we aimed to investigate MRI correlates of cognitive improvement after EEG-based neurofeedback training in patients...

Showing 385 to 393 of 393 entries