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Unfolding Mechanisms and Conformational Stability of the Dimeric Endophilin N-BAR Domain.

ACS omega

Jin R, Grasso M, Zhou M, Marmorstein R, Baumgart T.
PMID: 34423187
ACS Omega. 2021 Aug 04;6(32):20790-20803. doi: 10.1021/acsomega.1c01905. eCollection 2021 Aug 17.

Endophilin, which is a member of the Bin-amphiphysin-Rvs (BAR) domain protein superfamily, contains a homodimeric N-BAR domain of a characteristic crescent shape. The N-BAR domain comprises a six-helix bundle and is known to sense and generate membrane curvature. Here,...

Autophagy modulates cell fate decisions during lineage commitment.

Autophagy

Sharma K, Asp NT, Harrison SP, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A.
PMID: 34923909
Autophagy. 2021 Dec 19;1-17. doi: 10.1080/15548627.2021.2008691. Epub 2021 Dec 19.

Early events during development leading to exit from a pluripotent state and commitment toward a specific germ layer still need in depth understanding. Autophagy has been shown to play a crucial role in both development and differentiation. This study...

Extended Primary Anastomosis With Penile Plication (EPAPP): A Promising New Alternative to Perineal Urethrostomy for Reconstruction of Long Urethral Strictures.

Urology

VanDyke ME, Baumgarten AS, Ortiz NM, Dropkin BM, Joice GA, Khouri RK, Filho JEP, Ward EE, Hudak SJ, Morey AF.
PMID: 33301744
Urology. 2021 Mar;149:245-250. doi: 10.1016/j.urology.2020.11.048. Epub 2020 Dec 07.

OBJECTIVE: At present, excision and primary anastomosis (EPA) urethroplasty is a highly reliable method of reconstruction for short bulbar urethral strictures. Longer strictures are often managed with grafting techniques to ensure a tension-free repair. Here we report our initial...

Showing 457 to 459 of 459 entries