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Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates.

Frontiers in pharmacology

Badr-Eldin SM, Alhakamy NA, Fahmy UA, Ahmed OAA, Asfour HZ, Althagafi AA, Aldawsari HM, Rizg WY, Mahdi WA, Alghaith AF, Alshehri S, Caraci F, Caruso G.
PMID: 33633571
Front Pharmacol. 2021 Feb 03;11:642171. doi: 10.3389/fphar.2020.642171. eCollection 2020.

Fluvastatin (FLV) is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor often used to lower total and low-density lipoprotein (LDL) cholesterol and for the prevention of adverse cardiovascular events. This drug as well as melittin (MEL), the major component of...

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Badr-Eldin SM, Alhakamy NA, Fahmy UA, et al. Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates. Front Pharmacol. 2021;11:642171doi: 10.3389/fphar.2020.642171.
Badr-Eldin, S. M., Alhakamy, N. A., Fahmy, U. A., Ahmed, O. A. A., Asfour, H. Z., Althagafi, A. A., Aldawsari, H. M., Rizg, W. Y., Mahdi, W. A., Alghaith, A. F., Alshehri, S., Caraci, F., & Caruso, G. (2020). Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates. Frontiers in pharmacology, 11642171. https://doi.org/10.3389/fphar.2020.642171
Badr-Eldin, Shaimaa M, et al. "Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates." Frontiers in pharmacology vol. 11 (2020): 642171. doi: https://doi.org/10.3389/fphar.2020.642171
Badr-Eldin SM, Alhakamy NA, Fahmy UA, Ahmed OAA, Asfour HZ, Althagafi AA, Aldawsari HM, Rizg WY, Mahdi WA, Alghaith AF, Alshehri S, Caraci F, Caruso G. Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates. Front Pharmacol. 2021 Feb 03;11:642171. doi: 10.3389/fphar.2020.642171. eCollection 2020. PMID: 33633571; PMCID: PMC7901935.
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Left ventricular dysfunction and cardiac autonomic imbalance in children with drug-resistant epilepsy.

Epilepsy research

Ibrahim A, Soliman WM, Mesbah BEM, Salem AS.
PMID: 34252747
Epilepsy Res. 2021 Oct;176:106709. doi: 10.1016/j.eplepsyres.2021.106709. Epub 2021 Jul 07.

BACKGROUND: Resistance to antiepileptic drug treatment increases the risk of comorbidities and mortality due to a cardio-autonomic imbalance and left ventricular (LV) dysfunction.OBJECTIVE: To assess the prevalence of LV dysfunction and cardio-autonomic imbalance in children with drug-resistant epilepsy (DRE).PATIENTS...

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Ibrahim A, Soliman WM, Mesbah BEM, et al. Left ventricular dysfunction and cardiac autonomic imbalance in children with drug-resistant epilepsy. Epilepsy Res. 2021;176:106709doi: 10.1016/j.eplepsyres.2021.106709.
Ibrahim, A., Soliman, W. M., Mesbah, B. E. M., & Salem, A. S. (2021). Left ventricular dysfunction and cardiac autonomic imbalance in children with drug-resistant epilepsy. Epilepsy research, 176106709. https://doi.org/10.1016/j.eplepsyres.2021.106709
Ibrahim, Ahmed, et al. "Left ventricular dysfunction and cardiac autonomic imbalance in children with drug-resistant epilepsy." Epilepsy research vol. 176 (2021): 106709. doi: https://doi.org/10.1016/j.eplepsyres.2021.106709
Ibrahim A, Soliman WM, Mesbah BEM, Salem AS. Left ventricular dysfunction and cardiac autonomic imbalance in children with drug-resistant epilepsy. Epilepsy Res. 2021 Oct;176:106709. doi: 10.1016/j.eplepsyres.2021.106709. Epub 2021 Jul 07. PMID: 34252747.
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Coconut oil-based resveratrol nanoemulsion: Optimization using response surface methodology, stability assessment and pharmacokinetic evaluation.

Food chemistry

Kotta S, Mubarak Aldawsari H, Badr-Eldin SM, Alhakamy NA, Md S.
PMID: 33866243
Food Chem. 2021 Apr 05;357:129721. doi: 10.1016/j.foodchem.2021.129721. Epub 2021 Apr 05.

Phytochemicals are widely studied for therapeutic applications and nanostructured delivery systems for phytochemicals are under spotlight. Resveratrol is a promising candidate for neurodegenerative disorders. In the present study, we aimed to formulate nanoemulsion of resveratrol by ultrasonication process using...

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Kotta S, Mubarak Aldawsari H, Badr-Eldin SM, et al. Coconut oil-based resveratrol nanoemulsion: Optimization using response surface methodology, stability assessment and pharmacokinetic evaluation. Food Chem. 2021;357:129721doi: 10.1016/j.foodchem.2021.129721.
Kotta, S., Mubarak Aldawsari, H., Badr-Eldin, S. M., Alhakamy, N. A., & Md, S. (2021). Coconut oil-based resveratrol nanoemulsion: Optimization using response surface methodology, stability assessment and pharmacokinetic evaluation. Food chemistry, 357129721. https://doi.org/10.1016/j.foodchem.2021.129721
Kotta, Sabna, et al. "Coconut oil-based resveratrol nanoemulsion: Optimization using response surface methodology, stability assessment and pharmacokinetic evaluation." Food chemistry vol. 357 (2021): 129721. doi: https://doi.org/10.1016/j.foodchem.2021.129721
Kotta S, Mubarak Aldawsari H, Badr-Eldin SM, Alhakamy NA, Md S. Coconut oil-based resveratrol nanoemulsion: Optimization using response surface methodology, stability assessment and pharmacokinetic evaluation. Food Chem. 2021 Apr 05;357:129721. doi: 10.1016/j.foodchem.2021.129721. Epub 2021 Apr 05. PMID: 33866243.
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The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells.

Pharmaceutics

Fahmy UA, Aldawsari HM, Badr-Eldin SM, Ahmed OAA, Alhakamy NA, Alsulimani HH, Caraci F, Caruso G.
PMID: 33050567
Pharmaceutics. 2020 Oct 11;12(10). doi: 10.3390/pharmaceutics12100956.

Febuxostat (FBX) is a drug able to inhibit xanthine oxidase and reduce uric acid production commonly used for the treatment of hyperuricemia in subjects suffering from gout. Several studies have also been directed at its use as anti-cancer drug...

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Fahmy UA, Aldawsari HM, Badr-Eldin SM, et al. The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells. Pharmaceutics. 2020;12(10)doi: 10.3390/pharmaceutics12100956.
Fahmy, U. A., Aldawsari, H. M., Badr-Eldin, S. M., Ahmed, O. A. A., Alhakamy, N. A., Alsulimani, H. H., Caraci, F., & Caruso, G. (2020). The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells. Pharmaceutics, 12(10), . https://doi.org/10.3390/pharmaceutics12100956
Fahmy, Usama A, et al. "The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells." Pharmaceutics vol. 12,10 (2020). doi: https://doi.org/10.3390/pharmaceutics12100956
Fahmy UA, Aldawsari HM, Badr-Eldin SM, Ahmed OAA, Alhakamy NA, Alsulimani HH, Caraci F, Caruso G. The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells. Pharmaceutics. 2020 Oct 11;12(10). doi: 10.3390/pharmaceutics12100956. PMID: 33050567; PMCID: PMC7600960.
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Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells.

Pharmaceutics

Alhakamy NA, Badr-Eldin SM, A Fahmy U, Alruwaili NK, Awan ZA, Caruso G, Alfaleh MA, Alaofi AL, Arif FO, Ahmed OAA, Alghaith AF.
PMID: 32806507
Pharmaceutics. 2020 Aug 12;12(8). doi: 10.3390/pharmaceutics12080761.

Thymoquinone (TQ), a natural polyphenol, has been associated with various pharmacological responses; however, low bioavailability of TQ limits its clinical application. Thus, a novel phytosomal delivery system of TQ-Phospholipon

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Alhakamy NA, Badr-Eldin SM, A Fahmy U, et al. Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells. Pharmaceutics. 2020;12(8)doi: 10.3390/pharmaceutics12080761.
Alhakamy, N. A., Badr-Eldin, S. M., A Fahmy, U., Alruwaili, N. K., Awan, Z. A., Caruso, G., Alfaleh, M. A., Alaofi, A. L., Arif, F. O., Ahmed, O. A. A., & Alghaith, A. F. (2020). Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells. Pharmaceutics, 12(8), . https://doi.org/10.3390/pharmaceutics12080761
Alhakamy, Nabil A, et al. "Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells." Pharmaceutics vol. 12,8 (2020). doi: https://doi.org/10.3390/pharmaceutics12080761
Alhakamy NA, Badr-Eldin SM, A Fahmy U, Alruwaili NK, Awan ZA, Caruso G, Alfaleh MA, Alaofi AL, Arif FO, Ahmed OAA, Alghaith AF. Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells. Pharmaceutics. 2020 Aug 12;12(8). doi: 10.3390/pharmaceutics12080761. PMID: 32806507; PMCID: PMC7463966.
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Polysaccharide production by Aureobasidium pullulans: factors affecting polysaccharide formation.

World journal of microbiology & biotechnology

Badr-Eldin SM, El-Tayeb OM, El-Masry HG, Mohamad FH, El-Rahman OA.
PMID: 24421090
World J Microbiol Biotechnol. 1994 Jul;10(4):423-6. doi: 10.1007/BF00144465.

Aureobasidium pullulans NRRL 6220 synthesized polysaccharide most actively in media containing sucrose, fructose or maltose with (NH4)2SO4 (0.6 g/l) or ammonium acetate giving greatest yields of the polysaccharide. With (NH4)2SO4 at ≥1.2 g/l, production of polysaccharide was decreased considerably....

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Badr-Eldin SM, El-Tayeb OM, El-Masry HG, et al. Polysaccharide production by Aureobasidium pullulans: factors affecting polysaccharide formation. World J Microbiol Biotechnol. 1994;10(4):423-6doi: 10.1007/BF00144465.
Badr-Eldin, S. M., El-Tayeb, O. M., El-Masry, H. G., Mohamad, F. H., & El-Rahman, O. A. (1994). Polysaccharide production by Aureobasidium pullulans: factors affecting polysaccharide formation. World journal of microbiology & biotechnology, 10(4), 423-6. https://doi.org/10.1007/BF00144465
Badr-Eldin, S M, et al. "Polysaccharide production by Aureobasidium pullulans: factors affecting polysaccharide formation." World journal of microbiology & biotechnology vol. 10,4 (1994): 423-6. doi: https://doi.org/10.1007/BF00144465
Badr-Eldin SM, El-Tayeb OM, El-Masry HG, Mohamad FH, El-Rahman OA. Polysaccharide production by Aureobasidium pullulans: factors affecting polysaccharide formation. World J Microbiol Biotechnol. 1994 Jul;10(4):423-6. doi: 10.1007/BF00144465. PMID: 24421090.
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Optimized Chitosan/Anion Polyelectrolyte Complex Based Inserts for Vaginal Delivery of Fluconazole: In Vitro/In Vivo Evaluation.

Pharmaceutics

Darwesh B, Aldawsari HM, Badr-Eldin SM.
PMID: 30424501
Pharmaceutics. 2018 Nov 12;10(4). doi: 10.3390/pharmaceutics10040227.

(1) Background: Fluconazole, used orally for vaginal candidiasis, has reported gastrointestinal side effects. Therefore, researchers directed towards the drug vaginal delivery. However, vaginal delivery is limited by poor retention and leakage. Thus, this work aimed at exploring chitosan/anion polyelectrolyte...

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Darwesh B, Aldawsari HM, Badr-Eldin SM. Optimized Chitosan/Anion Polyelectrolyte Complex Based Inserts for Vaginal Delivery of Fluconazole: In Vitro/In Vivo Evaluation. Pharmaceutics. 2018;10(4)doi: 10.3390/pharmaceutics10040227.
Darwesh, B., Aldawsari, H. M., & Badr-Eldin, S. M. (2018). Optimized Chitosan/Anion Polyelectrolyte Complex Based Inserts for Vaginal Delivery of Fluconazole: In Vitro/In Vivo Evaluation. Pharmaceutics, 10(4), . https://doi.org/10.3390/pharmaceutics10040227
Darwesh, Bayan, et al. "Optimized Chitosan/Anion Polyelectrolyte Complex Based Inserts for Vaginal Delivery of Fluconazole: In Vitro/In Vivo Evaluation." Pharmaceutics vol. 10,4 (2018). doi: https://doi.org/10.3390/pharmaceutics10040227
Darwesh B, Aldawsari HM, Badr-Eldin SM. Optimized Chitosan/Anion Polyelectrolyte Complex Based Inserts for Vaginal Delivery of Fluconazole: In Vitro/In Vivo Evaluation. Pharmaceutics. 2018 Nov 12;10(4). doi: 10.3390/pharmaceutics10040227. PMID: 30424501; PMCID: PMC6321472.
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Piceatannol-Loaded Bilosome-Stabilized Zein Protein Exhibits Enhanced Cytostatic and Apoptotic Activities in Lung Cancer Cells.

Pharmaceutics

Alhakamy NA, Caruso G, Al-Rabia MW, Badr-Eldin SM, Aldawsari HM, Asfour HZ, Alshehri S, Alzaharani SH, Alhamdan MM, Rizg WY, Allam AN.
PMID: 33947103
Pharmaceutics. 2021 Apr 29;13(5). doi: 10.3390/pharmaceutics13050638.

Piceatannol (PIC) is a naturally occurring polyphenolic stilbene, and it has pleiotropic pharmacological properties. Moreover, PIC has cytotoxic actions among various cancer cells. In this work, preparations of PIC-loaded bilosome-zein (PIC-BZ) were designed, formulated, and characterized, and the optimized...

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Alhakamy NA, Caruso G, Al-Rabia MW, et al. Piceatannol-Loaded Bilosome-Stabilized Zein Protein Exhibits Enhanced Cytostatic and Apoptotic Activities in Lung Cancer Cells. Pharmaceutics. 2021;13(5)doi: 10.3390/pharmaceutics13050638.
Alhakamy, N. A., Caruso, G., Al-Rabia, M. W., Badr-Eldin, S. M., Aldawsari, H. M., Asfour, H. Z., Alshehri, S., Alzaharani, S. H., Alhamdan, M. M., Rizg, W. Y., & Allam, A. N. (2021). Piceatannol-Loaded Bilosome-Stabilized Zein Protein Exhibits Enhanced Cytostatic and Apoptotic Activities in Lung Cancer Cells. Pharmaceutics, 13(5), . https://doi.org/10.3390/pharmaceutics13050638
Alhakamy, Nabil A, et al. "Piceatannol-Loaded Bilosome-Stabilized Zein Protein Exhibits Enhanced Cytostatic and Apoptotic Activities in Lung Cancer Cells." Pharmaceutics vol. 13,5 (2021). doi: https://doi.org/10.3390/pharmaceutics13050638
Alhakamy NA, Caruso G, Al-Rabia MW, Badr-Eldin SM, Aldawsari HM, Asfour HZ, Alshehri S, Alzaharani SH, Alhamdan MM, Rizg WY, Allam AN. Piceatannol-Loaded Bilosome-Stabilized Zein Protein Exhibits Enhanced Cytostatic and Apoptotic Activities in Lung Cancer Cells. Pharmaceutics. 2021 Apr 29;13(5). doi: 10.3390/pharmaceutics13050638. PMID: 33947103; PMCID: PMC8146359.
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Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment.

Pharmaceutics

Aldawsari HM, Ahmed OAA, Alhakamy NA, Neamatallah T, Fahmy UA, Badr-Eldin SM.
PMID: 34073780
Pharmaceutics. 2021 May 24;13(6). doi: 10.3390/pharmaceutics13060783.

Raloxifene hydrochloride (RLX), an antiosteoporotic agent, has been utilized for guarding against breast cancer and recently, for the disease management owing to its estrogen antagonist activity. Nevertheless, RLX exhibits poor bioavailability that could be attributed to reduced water solubility...

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Aldawsari HM, Ahmed OAA, Alhakamy NA, et al. Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment. Pharmaceutics. 2021;13(6)doi: 10.3390/pharmaceutics13060783.
Aldawsari, H. M., Ahmed, O. A. A., Alhakamy, N. A., Neamatallah, T., Fahmy, U. A., & Badr-Eldin, S. M. (2021). Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment. Pharmaceutics, 13(6), . https://doi.org/10.3390/pharmaceutics13060783
Aldawsari, Hibah M, et al. "Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment." Pharmaceutics vol. 13,6 (2021). doi: https://doi.org/10.3390/pharmaceutics13060783
Aldawsari HM, Ahmed OAA, Alhakamy NA, Neamatallah T, Fahmy UA, Badr-Eldin SM. Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment. Pharmaceutics. 2021 May 24;13(6). doi: 10.3390/pharmaceutics13060783. PMID: 34073780; PMCID: PMC8225169.
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Gum Acacia Functionalized Colloidal Gold Nanoparticles of Letrozole as Biocompatible Drug Delivery Carrier for Treatment of Breast Cancer.

Pharmaceutics

Aldawsari HM, Singh S, Alhakamy NA, Bakhaidar RB, Halwani AA, Badr-Eldin SM.
PMID: 34683847
Pharmaceutics. 2021 Sep 24;13(10). doi: 10.3390/pharmaceutics13101554.

The most prevalent malignancy among postmenopausal women is breast cancer. It is one of the leading causes of cancer-related mortality among women. Letrozole (LTZ) is a clinically approved inhibitor for breast cancer in postmenopausal women. However, due to poor...

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Aldawsari HM, Singh S, Alhakamy NA, et al. Gum Acacia Functionalized Colloidal Gold Nanoparticles of Letrozole as Biocompatible Drug Delivery Carrier for Treatment of Breast Cancer. Pharmaceutics. 2021;13(10)doi: 10.3390/pharmaceutics13101554.
Aldawsari, H. M., Singh, S., Alhakamy, N. A., Bakhaidar, R. B., Halwani, A. A., & Badr-Eldin, S. M. (2021). Gum Acacia Functionalized Colloidal Gold Nanoparticles of Letrozole as Biocompatible Drug Delivery Carrier for Treatment of Breast Cancer. Pharmaceutics, 13(10), . https://doi.org/10.3390/pharmaceutics13101554
Aldawsari, Hibah M, et al. "Gum Acacia Functionalized Colloidal Gold Nanoparticles of Letrozole as Biocompatible Drug Delivery Carrier for Treatment of Breast Cancer." Pharmaceutics vol. 13,10 (2021). doi: https://doi.org/10.3390/pharmaceutics13101554
Aldawsari HM, Singh S, Alhakamy NA, Bakhaidar RB, Halwani AA, Badr-Eldin SM. Gum Acacia Functionalized Colloidal Gold Nanoparticles of Letrozole as Biocompatible Drug Delivery Carrier for Treatment of Breast Cancer. Pharmaceutics. 2021 Sep 24;13(10). doi: 10.3390/pharmaceutics13101554. PMID: 34683847; PMCID: PMC8538880.
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Application of Nanopharmaceutics for Flibanserin Brain Delivery Augmentation Via the Nasal Route.

Nanomaterials (Basel, Switzerland)

Ahmed OAA, Fahmy UA, Badr-Eldin SM, Aldawsari HM, Awan ZA, Asfour HZ, Kammoun AK, Caruso G, Caraci F, Alfarsi A, Al-Ghamdi RA, Al-Ghamdi RA, Alhakamy NA.
PMID: 32610539
Nanomaterials (Basel). 2020 Jun 29;10(7). doi: 10.3390/nano10071270.

Flibanserin (FLB) is a nonhormonal medicine approved by the Food and Drug Administration (FDA) to treat the hypoactive sexual appetite disorder in females. However, the peroral administration of the medicine is greatly affected by its poor bioavailability as a...

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Ahmed OAA, Fahmy UA, Badr-Eldin SM, et al. Application of Nanopharmaceutics for Flibanserin Brain Delivery Augmentation Via the Nasal Route. Nanomaterials (Basel). 2020;10(7)doi: 10.3390/nano10071270.
Ahmed, O. A. A., Fahmy, U. A., Badr-Eldin, S. M., Aldawsari, H. M., Awan, Z. A., Asfour, H. Z., Kammoun, A. K., Caruso, G., Caraci, F., Alfarsi, A., Al-Ghamdi, R. A., Al-Ghamdi, R. A., & Alhakamy, N. A. (2020). Application of Nanopharmaceutics for Flibanserin Brain Delivery Augmentation Via the Nasal Route. Nanomaterials (Basel, Switzerland), 10(7), . https://doi.org/10.3390/nano10071270
Ahmed, Osama A A, et al. "Application of Nanopharmaceutics for Flibanserin Brain Delivery Augmentation Via the Nasal Route." Nanomaterials (Basel, Switzerland) vol. 10,7 (2020). doi: https://doi.org/10.3390/nano10071270
Ahmed OAA, Fahmy UA, Badr-Eldin SM, Aldawsari HM, Awan ZA, Asfour HZ, Kammoun AK, Caruso G, Caraci F, Alfarsi A, Al-Ghamdi RA, Al-Ghamdi RA, Alhakamy NA. Application of Nanopharmaceutics for Flibanserin Brain Delivery Augmentation Via the Nasal Route. Nanomaterials (Basel). 2020 Jun 29;10(7). doi: 10.3390/nano10071270. PMID: 32610539; PMCID: PMC7408465.
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Intranasal Niosomal .

Pharmaceutics

Fahmy UA, Badr-Eldin SM, Ahmed OAA, Aldawsari HM, Tima S, Asfour HZ, Al-Rabia MW, Negm AA, Sultan MH, Madkhali OAA, Alhakamy NA.
PMID: 32471119
Pharmaceutics. 2020 May 27;12(6). doi: 10.3390/pharmaceutics12060485.

Flibanserin (FLB) is a multifunctional serotonergic agent that was recently approved by the FDA for the oral treatment of premenopausal women with hypoactive sexual desire disorder. FLB is a centrally acting drug that has a low oral bioavailability of...

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Fahmy UA, Badr-Eldin SM, Ahmed OAA, et al. Intranasal Niosomal . Pharmaceutics. 2020;12(6)doi: 10.3390/pharmaceutics12060485.
Fahmy, U. A., Badr-Eldin, S. M., Ahmed, O. A. A., Aldawsari, H. M., Tima, S., Asfour, H. Z., Al-Rabia, M. W., Negm, A. A., Sultan, M. H., Madkhali, O. A. A., & Alhakamy, N. A. (2020). Intranasal Niosomal . Pharmaceutics, 12(6), . https://doi.org/10.3390/pharmaceutics12060485
Fahmy, Usama A, et al. "Intranasal Niosomal ." Pharmaceutics vol. 12,6 (2020). doi: https://doi.org/10.3390/pharmaceutics12060485
Fahmy UA, Badr-Eldin SM, Ahmed OAA, Aldawsari HM, Tima S, Asfour HZ, Al-Rabia MW, Negm AA, Sultan MH, Madkhali OAA, Alhakamy NA. Intranasal Niosomal . Pharmaceutics. 2020 May 27;12(6). doi: 10.3390/pharmaceutics12060485. PMID: 32471119; PMCID: PMC7356232.
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