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Showing 25 to 36 of 173 entries
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A commentary on youth onset bipolar disorder.

Bipolar disorders

Singh MK, Post RM, Miklowitz DJ, Birmaher B, Youngstrom E, Goldstein B, Soutullo C, Axelson D, Chang KD, DelBello MP.
PMID: 34689401
Bipolar Disord. 2021 Oct 24; doi: 10.1111/bdi.13148. Epub 2021 Oct 24.

AIM: Given ongoing disagreement about the diagnosis of pediatric bipolar disorder, we sought to illuminate key empirical findings regarding the condition in children and adolescents.METHODS: We conducted a review of extant studies of the diagnosis, course, and treatment of...

The history and evolution of the Denisovan-.

Proceedings of the National Academy of Sciences of the United States of America

Zhang X, Witt KE, Bañuelos MM, Ko A, Yuan K, Xu S, Nielsen R, Huerta-Sanchez E.
PMID: 34050022
Proc Natl Acad Sci U S A. 2021 Jun 01;118(22). doi: 10.1073/pnas.2020803118.

Recent studies suggest that admixture with archaic hominins played an important role in facilitating biological adaptations to new environments. For example, interbreeding with Denisovans facilitated the adaptation to high-altitude environments on the Tibetan Plateau. Specifically, the

Medical malpractice in Norway: frequency and distribution of disciplinary actions for medical doctors 2011-2018.

BMC health services research

Harbitz MB, Stensland PS, Abelsen B.
PMID: 33836746
BMC Health Serv Res. 2021 Apr 09;21(1):324. doi: 10.1186/s12913-021-06334-2.

BACKGROUND: Physicians who perform unsafe practices and harm patients may be disciplined. In Norway, there are five types of disciplinary action, ranging from a warning for the least serious examples of malpractice to loss of licence for the most...

No statistical evidence for an effect of CCR5-∆32 on lifespan in the UK Biobank cohort.

Nature medicine

Maier R, Akbari A, Wei X, Patterson N, Nielsen R, Reich D.
PMID: 31873311
Nat Med. 2020 Feb;26(2):178-180. doi: 10.1038/s41591-019-0710-1. Epub 2019 Dec 23.

No abstract available.

AncestralClust: Clustering of Divergent Nucleotide Sequences by Ancestral Sequence Reconstruction using Phylogenetic Trees.

Bioinformatics (Oxford, England)

Pipes L, Nielsen R.
PMID: 34668516
Bioinformatics. 2021 Oct 20; doi: 10.1093/bioinformatics/btab723. Epub 2021 Oct 20.

MOTIVATION: Clustering is a fundamental task in the analysis of nucleotide sequences. Despite the exponential increase in the size of sequence databases of homologous genes, few methods exist to cluster divergent sequences. Traditional clustering methods have mostly focused on...

99mTc-HMPAO-WBC SPECT/CT versus 18F-FDG-WBC PET/CT in chronic prosthetic joint infection: a pilot study.

Nuclear medicine communications

Teiler J, Ahl M, Åkerlund B, Brismar H, Holstensson M, Gabrielson S, Hedlund H, Axelsson R.
PMID: 34678830
Nucl Med Commun. 2021 Oct 20; doi: 10.1097/MNM.0000000000001502. Epub 2021 Oct 20.

PURPOSE: The aim of this study was to compare 99mTc-HMPAO-WBC-SPECT/CT combined with 99mTc-nanocollloid SPECT/CT and 18F-FDG-WBC-PET/CT combined with 99mTc-Nanocollloid SPECT/CT for the diagnosis and treatment evaluation of chronic prosthetic joint infection (PJI).METHODS: Patients with suspected chronic PJI were examined...

Respiratory symptoms and respiratory deaths: A multi-cohort study with 45 years observation time.

PloS one

Stavem K, Johannessen A, Nielsen R, Gulsvik A.
PMID: 34807953
PLoS One. 2021 Nov 22;16(11):e0260416. doi: 10.1371/journal.pone.0260416. eCollection 2021.

This study determined the association between respiratory symptoms and death from respiratory causes over a period of 45 years. In four cohorts of random samples of Norwegian populations with 103,881 participants, 43,731 persons had died per 31 December 2016....

Role of Polygenic Risk Score in the Familial Transmission of Bipolar Disorder in Youth.

JAMA psychiatry

Birmaher B, Hafeman D, Merranko J, Zwicker A, Goldstein B, Goldstein T, Axelson D, Monk K, Hickey MB, Sakolsky D, Iyengar S, Diler R, Nimgaonkar V, Uher R.
PMID: 34935868
JAMA Psychiatry. 2021 Dec 22; doi: 10.1001/jamapsychiatry.2021.3700. Epub 2021 Dec 22.

IMPORTANCE: Establishing genetic contributions to the transmission of bipolar disorder (BD) from parents to offspring may inform the risk of developing this disorder and further serve to validate BD in youth.OBJECTIVE: To evaluate the specific association of BD polygenic...

Role of Polygenic Risk Score in the Familial Transmission of Bipolar Disorder in Youth.

JAMA psychiatry

Birmaher B, Hafeman D, Merranko J, Zwicker A, Goldstein B, Goldstein T, Axelson D, Monk K, Hickey MB, Sakolsky D, Iyengar S, Diler R, Nimgaonkar V, Uher R.
PMID: 34935868
JAMA Psychiatry. 2021 Dec 22; doi: 10.1001/jamapsychiatry.2021.3700. Epub 2021 Dec 22.

IMPORTANCE: Establishing genetic contributions to the transmission of bipolar disorder (BD) from parents to offspring may inform the risk of developing this disorder and further serve to validate BD in youth.OBJECTIVE: To evaluate the specific association of BD polygenic...

AncestralClust: Clustering of Divergent Nucleotide Sequences by Ancestral Sequence Reconstruction using Phylogenetic Trees.

Bioinformatics (Oxford, England)

Pipes L, Nielsen R.
PMID: 34668516
Bioinformatics. 2021 Oct 20; doi: 10.1093/bioinformatics/btab723. Epub 2021 Oct 20.

MOTIVATION: Clustering is a fundamental task in the analysis of nucleotide sequences. Despite the exponential increase in the size of sequence databases of homologous genes, few methods exist to cluster divergent sequences. Traditional clustering methods have mostly focused on...

Rhea, the reaction knowledgebase in 2022.

Nucleic acids research

Bansal P, Morgat A, Axelsen KB, Muthukrishnan V, Coudert E, Aimo L, Hyka-Nouspikel N, Gasteiger E, Kerhornou A, Neto TB, Pozzato M, Blatter MC, Ignatchenko A, Redaschi N, Bridge A.
PMID: 34755880
Nucleic Acids Res. 2022 Jan 07;50:D693-D700. doi: 10.1093/nar/gkab1016.

Rhea (https://www.rhea-db.org) is an expert-curated knowledgebase of biochemical reactions based on the chemical ontology ChEBI (Chemical Entities of Biological Interest) (https://www.ebi.ac.uk/chebi). In this paper, we describe a number of key developments in Rhea since our last report in the...

Health care: no time for placebos.

New York affairs

Walsh JP, Adelson R.
PMID: 11614990
N Y Aff. 1978;5(2):151-61.

No abstract available.

Showing 25 to 36 of 173 entries