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Showing 1501 to 1503 of 1503 entries
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Extended Left Colectomy with Coloanal Anastomosis by Indocyanine Green-guided Deloyers Procedure: A Case Report.

Journal of the anus, rectum and colon

Okamoto K, Emoto S, Sasaki K, Nozawa H, Kawai K, Murono K, Iida Y, Ishii H, Yokoyama Y, Anzai H, Sonoda H, Ishihara S.
PMID: 33937563
J Anus Rectum Colon. 2021 Apr 28;5(2):202-206. doi: 10.23922/jarc.2020-097. eCollection 2021.

The Deloyers procedure is performed after extended left colectomy, enabling the reach of the proximal colon to the rectum for anastomosis while preserving sufficient blood supply. We report a case of the Deloyers procedure performed safely under indocyanine green...

An improved TK-NOG mouse as a novel platform for humanized liver that overcomes limitations in both male and female animals.

Drug metabolism and pharmacokinetics

Uehara S, Higuchi Y, Yoneda N, Kawai K, Yamamoto M, Kamimura H, Iida Y, Oshimura M, Kazuki Y, Yamazaki H, Hikita H, Takehara T, Suemizu H.
PMID: 34839181
Drug Metab Pharmacokinet. 2021 Jun 12;42:100410. doi: 10.1016/j.dmpk.2021.100410. Epub 2021 Jun 12.

We developed a novel immunodeficient NOG mouse expressing HSVtk mutant clone 30 cDNA under the control of mouse transthyretin gene enhancer/promoter (NOG-TKm30) to acquire fertility in males and high inducibility of liver injury in females. Maximum human albumin levels...

LCP: Simple Representation of Docking Poses for Machine Learning: A Case Study on Xanthine Oxidase Inhibitors.

Molecular informatics

Kawai K, Asanuma Y, Kato T, Karuo Y, Tarui A, Sato K, Omote M.
PMID: 34843171
Mol Inform. 2021 Nov 29;e2100245. doi: 10.1002/minf.202100245. Epub 2021 Nov 29.

In this paper, we propose a simple descriptor called the ligand coordinate profile (LCP) for describing docking poses. The LCP descriptor is generated from the coordinates of the polar hydrogen and heavy atoms of the docked ligand. We hypothesize...

Showing 1501 to 1503 of 1503 entries