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Showing 925 to 936 of 936 entries
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Clinically recognized varicose veins and physical function in older individuals: the ARIC study.

The journals of gerontology. Series A, Biological sciences and medical sciences

Mok Y, Ishigami J, Sang Y, Kucharska-Newton AM, Salameh M, Schrack JA, Palta P, Coresh J, Windham BG, Lutsey PL, Folsom AR, Matsushita K.
PMID: 34606610
J Gerontol A Biol Sci Med Sci. 2021 Oct 04; doi: 10.1093/gerona/glab287. Epub 2021 Oct 04.

BACKGROUND: Although a few studies reported an association between varicose veins and physical function, this potentially bi-directional association has not been systematically evaluated in the general population.METHODS: In 5,580 participants (aged 71-90 years) from the Atherosclerosis Risk in Communities...

The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Management of Metastatic and/or Unresectable Pheochromocytoma and Paraganglioma.

Pancreas

Fishbein L, Del Rivero J, Else T, Howe JR, Asa SL, Cohen DL, Dahia PLM, Fraker DL, Goodman KA, Hope TA, Kunz PL, Perez K, Perrier ND, Pryma DA, Ryder M, Sasson AR, Soulen MC, Jimenez C.
PMID: 33939658
Pancreas. 2021 Apr 01;50(4):469-493. doi: 10.1097/MPA.0000000000001792.

ABSTRACT: This manuscript is the result of the North American Neuroendocrine Tumor Society consensus conference on the medical management and surveillance of metastatic and unresectable pheochromocytoma and paraganglioma held on October 2 and 3, 2019. The panelists consisted of...

Internal Staging Discordance in National Cancer Databases for Non-Small Cell Lung Cancer.

The Annals of thoracic surgery

Dezube AR, Kucukak S, De Leon LE, Wiener DC, Rochefort MM, Jaklitsch MT.
PMID: 34461072
Ann Thorac Surg. 2021 Aug 27; doi: 10.1016/j.athoracsur.2021.07.079. Epub 2021 Aug 27.

BACKGROUND: The Surveillance, Epidemiology and End Results (SEER) and the National Cancer Database (NCDB) are databases for cancer analysis that may be subject to error in data reporting. This study examined the rates and impact of discordant data for...

The Future of Clinical Trial Design in Oncology.

Cancer discovery

Spreafico A, Hansen AR, Abdul Razak AR, Bedard PL, Siu LL.
PMID: 33811119
Cancer Discov. 2021 Apr;11(4):822-837. doi: 10.1158/2159-8290.CD-20-1301.

Clinical trials represent a fulcrum for oncology drug discovery and development to bring safe and effective medicines to patients in a timely manner. Clinical trials have shifted from traditional studies evaluating cytotoxic chemotherapy in largely histology-based populations to become...

Adverse Effects of Recreational and Medical Cannabis.

Psychopharmacology bulletin

Urits I, Charipova K, Gress K, Li N, Berger AA, Cornett EM, Kassem H, Ngo AL, Kaye AD, Viswanath O.
PMID: 33897066
Psychopharmacol Bull. 2021 Jan 12;51(1):94-109.

PURPOSE OF REVIEW: This comprehensive review discusses the adverse effects known today about marijuana, for either medical or recreational use. It reviews the role of cannabis in the treatment of chronic pain, cognitive and neurological adverse effects, special cases...

Pre-surgical and Post-surgical Aortic Aneurysm Maximum Diameter Measurement: Full Automation by Artificial Intelligence.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

Adam C, Fabre D, Mougin J, Zins M, Azarine A, Ardon R, d'Assignies G, Haulon S.
PMID: 34518071
Eur J Vasc Endovasc Surg. 2021 Sep 10; doi: 10.1016/j.ejvs.2021.07.013. Epub 2021 Sep 10.

OBJECTIVE: The aim of this study was to evaluate an automatic, deep learning based method (Augmented Radiology for Vascular Aneurysm [ARVA]), to detect and assess maximum aortic diameter, providing cross sectional outer to outer aortic wall measurements.METHODS: Accurate external...

Intraoperative Hypotension in a Patient with Antithrombin Deficiency, Bilateral Pulmonary Emboli, and Cefazolin Allergy.

Cureus

Muncey AR, Aldawoodi NN, Chitneni A, Hoffman JP, Escher AR.
PMID: 33665061
Cureus. 2021 Mar 02;13(3):e13653. doi: 10.7759/cureus.13653.

In medicine, the search for a clear answer can at times be elusive. However, this does not necessarily preclude the administration of intelligent and thoughtful therapeutic treatments. Here, we describe a complicated emergent event of severe hypotension and near-arrest...

Rates of Upstaging, Between Diagnosis and Surgery, and Clinical Management of Metastatic Cutaneous Squamous Cell Carcinoma: A Case-Control Study.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

Costello CM, Cumsky HJL, Severson KJ, Mi L, DiCaudo DJ, Ochoa SA, Baum CL, Mangold AR.
PMID: 34904573
Dermatol Surg. 2022 Jan 01;48(1):12-16. doi: 10.1097/DSS.0000000000003224.

BACKGROUND: Cutaneous squamous cell carcinomas (cSCC) have upstage rates of approximately 10.3% to 11.1%. Data are currently limited on the rate of upstaging for metastatic cSCC.OBJECTIVE: The aim of this study was to determine the rates of upstaging, between...

Analysis of the effects of aryl hydrocarbon receptor expression on cancer cell invasion .

Lab on a chip

Li BB, Scott EY, Olafsen NE, Matthews J, Wheeler AR.
PMID: 34904612
Lab Chip. 2021 Dec 14; doi: 10.1039/d1lc00854d. Epub 2021 Dec 14.

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that binds to xenobiotics and activates expression of response elements to metabolize these compounds. The AHR pathway has been associated with a long list of diseases including cancer; however,...

Pre-surgical and Post-surgical Aortic Aneurysm Maximum Diameter Measurement: Full Automation by Artificial Intelligence.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

Adam C, Fabre D, Mougin J, Zins M, Azarine A, Ardon R, d'Assignies G, Haulon S.
PMID: 34518071
Eur J Vasc Endovasc Surg. 2021 Dec;62(6):869-877. doi: 10.1016/j.ejvs.2021.07.013. Epub 2021 Sep 10.

OBJECTIVE: The aim of this study was to evaluate an automatic, deep learning based method (Augmented Radiology for Vascular Aneurysm [ARVA]), to detect and assess maximum aortic diameter, providing cross sectional outer to outer aortic wall measurements.METHODS: Accurate external...

Clinicopathologic Features of Gynecologic Malignancies Presenting Clinically as Colonic Malignancies.

American journal of clinical pathology

Fuller LD, Dunn A, Huber AR, Vyas M, Gonzalez RS.
PMID: 34302332
Am J Clin Pathol. 2021 Jul 24; doi: 10.1093/ajcp/aqab097. Epub 2021 Jul 24.

OBJECTIVES: To systematically evaluate gynecologic malignancies (adnexal or uterine) causing gastrointestinal (GI) signs (eg, mass on colonoscopy) or symptoms (eg, bloody stools) clinically mimicking a GI primary malignancy.METHODS: The archives of 2 institutions were retrospectively reviewed for gynecologic malignancies...

Elevated plasma free thiols are associated with early and one-year graft function in renal transplant recipients.

PloS one

Nielsen MB, Jespersen B, Birn H, Krogstrup NV, Bourgonje AR, Leuvenink HGD, van Goor H, Nørregaard R.
PMID: 34379701
PLoS One. 2021 Aug 11;16(8):e0255930. doi: 10.1371/journal.pone.0255930. eCollection 2021.

BACKGROUND: Reduced free thiols in plasma are indicative of oxidative stress, which is an important contributor to ischaemia-reperfusion injury (IRI) in kidney transplantation leading to kidney damage and possibly delayed graft function (DGF). In a post-hoc, exploratory analysis of...

Showing 925 to 936 of 936 entries