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Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome.

Frontiers in immunology

O'Connell AE, Volpi S, Dobbs K, Fiorini C, Tsitsikov E, de Boer H, Barlan IB, Despotovic JM, Espinosa-Rosales FJ, Hanson IC, Kanariou MG, Martínez-Beckerat R, Mayorga-Sirera A, Mejia-Carvajal C, Radwan N, Weiss AR, Pai SY, Lee YN, Notarangelo LD.
PMID: 25101082
Front Immunol. 2014 Jul 18;5:340. doi: 10.3389/fimmu.2014.00340. eCollection 2014.

The Wiskott-Aldrich syndrome (WAS) is due to mutations of the WAS gene encoding for the cytoskeletal WAS protein, leading to abnormal downstream signaling from the T cell and B cell antigen receptors (TCR and BCR). We hypothesized that the...

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O'Connell AE, Volpi S, Dobbs K, et al. Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome. Front Immunol. 2014;5:340doi: 10.3389/fimmu.2014.00340.
O'Connell, A. E., Volpi, S., Dobbs, K., Fiorini, C., Tsitsikov, E., de Boer, H., Barlan, I. B., Despotovic, J. M., Espinosa-Rosales, F. J., Hanson, I. C., Kanariou, M. G., Martínez-Beckerat, R., Mayorga-Sirera, A., Mejia-Carvajal, C., Radwan, N., Weiss, A. R., Pai, S. Y., Lee, Y. N., & Notarangelo, L. D. (2014). Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome. Frontiers in immunology, 5340. https://doi.org/10.3389/fimmu.2014.00340
O'Connell, Amy E, et al. "Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome." Frontiers in immunology vol. 5 (2014): 340. doi: https://doi.org/10.3389/fimmu.2014.00340
O'Connell AE, Volpi S, Dobbs K, Fiorini C, Tsitsikov E, de Boer H, Barlan IB, Despotovic JM, Espinosa-Rosales FJ, Hanson IC, Kanariou MG, Martínez-Beckerat R, Mayorga-Sirera A, Mejia-Carvajal C, Radwan N, Weiss AR, Pai SY, Lee YN, Notarangelo LD. Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome. Front Immunol. 2014 Jul 18;5:340. doi: 10.3389/fimmu.2014.00340. eCollection 2014. PMID: 25101082; PMCID: PMC4102881.
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Solitary Fibrous Tumor of the Sigmoid Colon Masquerading as an Adnexal Neoplasm.

Case reports in pathology

Bratton L, Salloum R, Cao W, Huber AR.
PMID: 27672467
Case Rep Pathol. 2016;2016:4182026. doi: 10.1155/2016/4182026. Epub 2016 Sep 08.

Solitary fibrous tumor is a rare, benign spindle cell neoplasm that was first described in the thoracic pleura. This tumor is now known to occur at many extrapleural sites. There are established criteria for the diagnosis of malignant solitary...

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Bratton L, Salloum R, Cao W, et al. Solitary Fibrous Tumor of the Sigmoid Colon Masquerading as an Adnexal Neoplasm. Case Rep Pathol. 2016;2016:4182026doi: 10.1155/2016/4182026.
Bratton, L., Salloum, R., Cao, W., & Huber, A. R. (2016). Solitary Fibrous Tumor of the Sigmoid Colon Masquerading as an Adnexal Neoplasm. Case reports in pathology, 20164182026. https://doi.org/10.1155/2016/4182026
Bratton, Laura, et al. "Solitary Fibrous Tumor of the Sigmoid Colon Masquerading as an Adnexal Neoplasm." Case reports in pathology vol. 2016 (2016): 4182026. doi: https://doi.org/10.1155/2016/4182026
Bratton L, Salloum R, Cao W, Huber AR. Solitary Fibrous Tumor of the Sigmoid Colon Masquerading as an Adnexal Neoplasm. Case Rep Pathol. 2016;2016:4182026. doi: 10.1155/2016/4182026. Epub 2016 Sep 08. PMID: 27672467; PMCID: PMC5031870.
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New perspectives on interdisciplinary earth science at the Dead Sea: The DESERVE project.

The Science of the total environment

Kottmeier C, Agnon A, Al-Halbouni D, Alpert P, Corsmeier U, Dahm T, Eshel A, Geyer S, Haas M, Holohan E, Kalthoff N, Kishcha P, Krawczyk C, Lati J, Laronne JB, Lott F, Mallast U, Merz R, Metzger J, Mohsen A, Morin E, Nied M, Rödiger T, Salameh E, Sawarieh A, Shannak B, Siebert C, Weber M.
PMID: 26779955
Sci Total Environ. 2016 Feb 15;544:1045-58. doi: 10.1016/j.scitotenv.2015.12.003. Epub 2016 Jan 09.

The Dead Sea region has faced substantial environmental challenges in recent decades, including water resource scarcity, ~1m annual decreases in the water level, sinkhole development, ascending-brine freshwater pollution, and seismic disturbance risks. Natural processes are significantly affected by human...

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Kottmeier C, Agnon A, Al-Halbouni D, et al. New perspectives on interdisciplinary earth science at the Dead Sea: The DESERVE project. Sci Total Environ. 2016;544:1045-58doi: 10.1016/j.scitotenv.2015.12.003.
Kottmeier, C., Agnon, A., Al-Halbouni, D., Alpert, P., Corsmeier, U., Dahm, T., Eshel, A., Geyer, S., Haas, M., Holohan, E., Kalthoff, N., Kishcha, P., Krawczyk, C., Lati, J., Laronne, J. B., Lott, F., Mallast, U., Merz, R., Metzger, J., Mohsen, A., Morin, E., Nied, M., Rödiger, T., Salameh, E., Sawarieh, A., Shannak, B., Siebert, C., & Weber, M. (2016). New perspectives on interdisciplinary earth science at the Dead Sea: The DESERVE project. The Science of the total environment, 5441045-58. https://doi.org/10.1016/j.scitotenv.2015.12.003
Kottmeier, Christoph, et al. "New perspectives on interdisciplinary earth science at the Dead Sea: The DESERVE project." The Science of the total environment vol. 544 (2016): 1045-58. doi: https://doi.org/10.1016/j.scitotenv.2015.12.003
Kottmeier C, Agnon A, Al-Halbouni D, Alpert P, Corsmeier U, Dahm T, Eshel A, Geyer S, Haas M, Holohan E, Kalthoff N, Kishcha P, Krawczyk C, Lati J, Laronne JB, Lott F, Mallast U, Merz R, Metzger J, Mohsen A, Morin E, Nied M, Rödiger T, Salameh E, Sawarieh A, Shannak B, Siebert C, Weber M. New perspectives on interdisciplinary earth science at the Dead Sea: The DESERVE project. Sci Total Environ. 2016 Feb 15;544:1045-58. doi: 10.1016/j.scitotenv.2015.12.003. Epub 2016 Jan 09. PMID: 26779955.
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Determining the optimal spectral sampling frequency and uncertainty thresholds for hyperspectral remote sensing of ocean color.

Optics express

Vandermeulen RA, Mannino A, Neeley A, Werdell J, Arnone R.
PMID: 29041046
Opt Express. 2017 Aug 07;25(16):A785-A797. doi: 10.1364/OE.25.00A785.

Using a modified geostatistical technique, empirical variograms were constructed from the first derivative of several diverse Remote Sensing Reflectance and Phytoplankton Absorbance spectra to describe how data points are correlated with "distance" across the spectra. The maximum rate of...

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Vandermeulen RA, Mannino A, Neeley A, et al. Determining the optimal spectral sampling frequency and uncertainty thresholds for hyperspectral remote sensing of ocean color. Opt Express. 2017;25(16):A785-A797doi: 10.1364/OE.25.00A785.
Vandermeulen, R. A., Mannino, A., Neeley, A., Werdell, J., & Arnone, R. (2017). Determining the optimal spectral sampling frequency and uncertainty thresholds for hyperspectral remote sensing of ocean color. Optics express, 25(16), A785-A797. https://doi.org/10.1364/OE.25.00A785
Vandermeulen, Ryan A, et al. "Determining the optimal spectral sampling frequency and uncertainty thresholds for hyperspectral remote sensing of ocean color." Optics express vol. 25,16 (2017): A785-A797. doi: https://doi.org/10.1364/OE.25.00A785
Vandermeulen RA, Mannino A, Neeley A, Werdell J, Arnone R. Determining the optimal spectral sampling frequency and uncertainty thresholds for hyperspectral remote sensing of ocean color. Opt Express. 2017 Aug 07;25(16):A785-A797. doi: 10.1364/OE.25.00A785. PMID: 29041046.
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Galectin-3 and Venous Thromboembolism Incidence: the Atherosclerosis Risk in Communities (ARIC) Study.

Research and practice in thrombosis and haemostasis

Fashanu OE, Heckbert SR, Aguilar D, Jensen PN, Ballantyne CM, Basu S, Hoogeveen RC, deFilippi C, Cushman M, Folsom AR.
PMID: 29152608
Res Pract Thromb Haemost. 2017 Oct;1(2):223-230. doi: 10.1002/rth2.12038. Epub 2017 Sep 04.

BACKGROUND: The inflammatory biomarker galectin-3 contributes to pathologic conditions such as heart failure and stimulates murine thrombogenesis. Its association with venous thromboembolism (VTE) has been sparsely studied.OBJECTIVES: To assess the prospective association of plasma galectin-3 and the METHODS: We...

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Fashanu OE, Heckbert SR, Aguilar D, et al. Galectin-3 and Venous Thromboembolism Incidence: the Atherosclerosis Risk in Communities (ARIC) Study. Res Pract Thromb Haemost. 2017;1(2):223-230doi: 10.1002/rth2.12038.
Fashanu, O. E., Heckbert, S. R., Aguilar, D., Jensen, P. N., Ballantyne, C. M., Basu, S., Hoogeveen, R. C., deFilippi, C., Cushman, M., & Folsom, A. R. (2017). Galectin-3 and Venous Thromboembolism Incidence: the Atherosclerosis Risk in Communities (ARIC) Study. Research and practice in thrombosis and haemostasis, 1(2), 223-230. https://doi.org/10.1002/rth2.12038
Fashanu, Oluwaseun E, et al. "Galectin-3 and Venous Thromboembolism Incidence: the Atherosclerosis Risk in Communities (ARIC) Study." Research and practice in thrombosis and haemostasis vol. 1,2 (2017): 223-230. doi: https://doi.org/10.1002/rth2.12038
Fashanu OE, Heckbert SR, Aguilar D, Jensen PN, Ballantyne CM, Basu S, Hoogeveen RC, deFilippi C, Cushman M, Folsom AR. Galectin-3 and Venous Thromboembolism Incidence: the Atherosclerosis Risk in Communities (ARIC) Study. Res Pract Thromb Haemost. 2017 Oct;1(2):223-230. doi: 10.1002/rth2.12038. Epub 2017 Sep 04. PMID: 29152608; PMCID: PMC5685543.
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Low rate of non-attenders to primary care providers in Israel - a retrospective longitudinal study.

Israel journal of health policy research

Rosen D, Nakar S, Cohen AD, Vinker S.
PMID: 24808941
Isr J Health Policy Res. 2014 Apr 25;3:15. doi: 10.1186/2045-4015-3-15. eCollection 2014.

BACKGROUND: A model that combines reactive and anticipatory care within routine consultations has become recognized as a cost-effective means of providing preventive health care, challenging the need of the periodic health examination. As such, opportunistic screening may be preferable...

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Rosen D, Nakar S, Cohen AD, et al. Low rate of non-attenders to primary care providers in Israel - a retrospective longitudinal study. Isr J Health Policy Res. 2014;3:15doi: 10.1186/2045-4015-3-15.
Rosen, D., Nakar, S., Cohen, A. D., & Vinker, S. (2014). Low rate of non-attenders to primary care providers in Israel - a retrospective longitudinal study. Israel journal of health policy research, 315. https://doi.org/10.1186/2045-4015-3-15
Rosen, Dana, et al. "Low rate of non-attenders to primary care providers in Israel - a retrospective longitudinal study." Israel journal of health policy research vol. 3 (2014): 15. doi: https://doi.org/10.1186/2045-4015-3-15
Rosen D, Nakar S, Cohen AD, Vinker S. Low rate of non-attenders to primary care providers in Israel - a retrospective longitudinal study. Isr J Health Policy Res. 2014 Apr 25;3:15. doi: 10.1186/2045-4015-3-15. eCollection 2014. PMID: 24808941; PMCID: PMC4012543.
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A rapid synthesis of high aspect ratio copper nanowires for high-performance transparent conducting films.

Chemical communications (Cambridge, England)

Ye S, Rathmell AR, Stewart IE, Ha YC, Wilson AR, Chen Z, Wiley BJ.
PMID: 24346590
Chem Commun (Camb). 2014 Mar 11;50(20):2562-4. doi: 10.1039/c3cc48561g.

This communication presents a way to produce copper nanowires with aspect ratios as high as 5700 in 30 min, and describes the growth processes responsible for their formation. These nanowires were used to make transparent conducting films with a...

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Ye S, Rathmell AR, Stewart IE, et al. A rapid synthesis of high aspect ratio copper nanowires for high-performance transparent conducting films. Chem Commun (Camb). 2014;50(20):2562-4doi: 10.1039/c3cc48561g.
Ye, S., Rathmell, A. R., Stewart, I. E., Ha, Y. C., Wilson, A. R., Chen, Z., & Wiley, B. J. (2014). A rapid synthesis of high aspect ratio copper nanowires for high-performance transparent conducting films. Chemical communications (Cambridge, England), 50(20), 2562-4. https://doi.org/10.1039/c3cc48561g
Ye, Shengrong, et al. "A rapid synthesis of high aspect ratio copper nanowires for high-performance transparent conducting films." Chemical communications (Cambridge, England) vol. 50,20 (2014): 2562-4. doi: https://doi.org/10.1039/c3cc48561g
Ye S, Rathmell AR, Stewart IE, Ha YC, Wilson AR, Chen Z, Wiley BJ. A rapid synthesis of high aspect ratio copper nanowires for high-performance transparent conducting films. Chem Commun (Camb). 2014 Mar 11;50(20):2562-4. doi: 10.1039/c3cc48561g. PMID: 24346590.
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Flow-Dependent Unfolding and Refolding of an RNA by Nonequilibrium Umbrella Sampling.

Journal of chemical theory and computation

Dickson A, Maienschein-Cline M, Tovo-Dwyer A, Hammond JR, Dinner AR.
PMID: 26605464
J Chem Theory Comput. 2011 Sep 13;7(9):2710-20. doi: 10.1021/ct200371n. Epub 2011 Aug 23.

Nonequilibrium experiments of single biomolecules such as force-induced unfolding reveal details about a few degrees of freedom of a complex system. Molecular dynamics simulations can provide complementary information, but exploration of the space of possible configurations is often hindered...

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Dickson A, Maienschein-Cline M, Tovo-Dwyer A, et al. Flow-Dependent Unfolding and Refolding of an RNA by Nonequilibrium Umbrella Sampling. J Chem Theory Comput. 2011;7(9):2710-20doi: 10.1021/ct200371n.
Dickson, A., Maienschein-Cline, M., Tovo-Dwyer, A., Hammond, J. R., & Dinner, A. R. (2011). Flow-Dependent Unfolding and Refolding of an RNA by Nonequilibrium Umbrella Sampling. Journal of chemical theory and computation, 7(9), 2710-20. https://doi.org/10.1021/ct200371n
Dickson, Alex, et al. "Flow-Dependent Unfolding and Refolding of an RNA by Nonequilibrium Umbrella Sampling." Journal of chemical theory and computation vol. 7,9 (2011): 2710-20. doi: https://doi.org/10.1021/ct200371n
Dickson A, Maienschein-Cline M, Tovo-Dwyer A, Hammond JR, Dinner AR. Flow-Dependent Unfolding and Refolding of an RNA by Nonequilibrium Umbrella Sampling. J Chem Theory Comput. 2011 Sep 13;7(9):2710-20. doi: 10.1021/ct200371n. Epub 2011 Aug 23. PMID: 26605464.
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Critical appraisal of extent of resection of clival lesions using the expanded endoscopic endonasal approach.

Journal of neurological surgery. Part B, Skull base

Cutler AR, Mundi JS, Solomon N, Suh JD, Wang MB, Bergsneider M.
PMID: 24436915
J Neurol Surg B Skull Base. 2013 Aug;74(4):217-24. doi: 10.1055/s-0033-1342915. Epub 2013 Apr 12.

Objectives To present a critical evaluation of our experience using an expanded endoscopic endonasal approach (EEEA) to clival lesions and evaluate, based on the location of residual tumor, what the anatomic limitations to the approach are. Design A retrospective...

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Cutler AR, Mundi JS, Solomon N, et al. Critical appraisal of extent of resection of clival lesions using the expanded endoscopic endonasal approach. J Neurol Surg B Skull Base. 2013;74(4):217-24doi: 10.1055/s-0033-1342915.
Cutler, A. R., Mundi, J. S., Solomon, N., Suh, J. D., Wang, M. B., & Bergsneider, M. (2013). Critical appraisal of extent of resection of clival lesions using the expanded endoscopic endonasal approach. Journal of neurological surgery. Part B, Skull base, 74(4), 217-24. https://doi.org/10.1055/s-0033-1342915
Cutler, Aaron R, et al. "Critical appraisal of extent of resection of clival lesions using the expanded endoscopic endonasal approach." Journal of neurological surgery. Part B, Skull base vol. 74,4 (2013): 217-24. doi: https://doi.org/10.1055/s-0033-1342915
Cutler AR, Mundi JS, Solomon N, Suh JD, Wang MB, Bergsneider M. Critical appraisal of extent of resection of clival lesions using the expanded endoscopic endonasal approach. J Neurol Surg B Skull Base. 2013 Aug;74(4):217-24. doi: 10.1055/s-0033-1342915. Epub 2013 Apr 12. PMID: 24436915; PMCID: PMC3715607.
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Phosphine-stabilised Au₉ clusters interacting with titania and silica surfaces: the first evidence for the density of states signature of the support-immobilised cluster.

The Journal of chemical physics

Andersson GG, Golovko VB, Alvino JF, Bennett T, Wrede O, Mejia SM, Al Qahtani HS, Adnan R, Gunby N, Anderson DP, Metha GF.
PMID: 25005298
J Chem Phys. 2014 Jul 07;141(1):014702. doi: 10.1063/1.4884642.

Chemically made, atomically precise phosphine-stabilized clusters Au9(PPh3)8(NO3)3 were deposited on titania and silica from solutions at various concentrations and the samples heated under vacuum to remove the ligands. Metastable induced electron spectroscopy was used to determine the density of...

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Andersson GG, Golovko VB, Alvino JF, et al. Phosphine-stabilised Au₉ clusters interacting with titania and silica surfaces: the first evidence for the density of states signature of the support-immobilised cluster. J Chem Phys. 2014;141(1):014702doi: 10.1063/1.4884642.
Andersson, G. G., Golovko, V. B., Alvino, J. F., Bennett, T., Wrede, O., Mejia, S. M., Al Qahtani, H. S., Adnan, R., Gunby, N., Anderson, D. P., & Metha, G. F. (2014). Phosphine-stabilised Au₉ clusters interacting with titania and silica surfaces: the first evidence for the density of states signature of the support-immobilised cluster. The Journal of chemical physics, 141(1), 014702. https://doi.org/10.1063/1.4884642
Andersson, Gunther G, et al. "Phosphine-stabilised Au₉ clusters interacting with titania and silica surfaces: the first evidence for the density of states signature of the support-immobilised cluster." The Journal of chemical physics vol. 141,1 (2014): 014702. doi: https://doi.org/10.1063/1.4884642
Andersson GG, Golovko VB, Alvino JF, Bennett T, Wrede O, Mejia SM, Al Qahtani HS, Adnan R, Gunby N, Anderson DP, Metha GF. Phosphine-stabilised Au₉ clusters interacting with titania and silica surfaces: the first evidence for the density of states signature of the support-immobilised cluster. J Chem Phys. 2014 Jul 07;141(1):014702. doi: 10.1063/1.4884642. PMID: 25005298.
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Correlated electrical and optical analysis of single nanoparticles and biomolecules on a nanopore-gated optofluidic chip.

Nano letters

Liu S, Zhao Y, Parks JW, Deamer DW, Hawkins AR, Schmidt H.
PMID: 25006747
Nano Lett. 2014 Aug 13;14(8):4816-20. doi: 10.1021/nl502400x. Epub 2014 Jul 11.

The analysis of individual biological nanoparticles has significantly advanced our understanding of fundamental biological processes but is also rapidly becoming relevant for molecular diagnostic applications in the emerging field of personalized medicine. Both optical and electrical methods for the...

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Liu S, Zhao Y, Parks JW, et al. Correlated electrical and optical analysis of single nanoparticles and biomolecules on a nanopore-gated optofluidic chip. Nano Lett. 2014;14(8):4816-20doi: 10.1021/nl502400x.
Liu, S., Zhao, Y., Parks, J. W., Deamer, D. W., Hawkins, A. R., & Schmidt, H. (2014). Correlated electrical and optical analysis of single nanoparticles and biomolecules on a nanopore-gated optofluidic chip. Nano letters, 14(8), 4816-20. https://doi.org/10.1021/nl502400x
Liu, Shuo, et al. "Correlated electrical and optical analysis of single nanoparticles and biomolecules on a nanopore-gated optofluidic chip." Nano letters vol. 14,8 (2014): 4816-20. doi: https://doi.org/10.1021/nl502400x
Liu S, Zhao Y, Parks JW, Deamer DW, Hawkins AR, Schmidt H. Correlated electrical and optical analysis of single nanoparticles and biomolecules on a nanopore-gated optofluidic chip. Nano Lett. 2014 Aug 13;14(8):4816-20. doi: 10.1021/nl502400x. Epub 2014 Jul 11. PMID: 25006747; PMCID: PMC4134182.
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Corrigendum: The genome of Chenopodium quinoa.

Nature

Jarvis DE, Ho YS, Lightfoot DJ, Schmöckel SM, Li B, Borm TJA, Ohyanagi H, Mineta K, Michell CT, Saber N, Kharbatia NM, Rupper RR, Sharp AR, Dally N, Boughton BA, Woo YH, Gao G, Schijlen EGWM, Guo X, Momin AA, Negrão S, Al-Babili S, Gehring C, Roessner U, Jung C, Murphy K, Arold ST, Gojobori T, van der Linden CG, van Loo EN, Jellen EN, Maughan PJ, Tester M.
PMID: 28489823
Nature. 2017 May 25;545(7655):510. doi: 10.1038/nature22384. Epub 2017 May 10.

This corrects the article DOI: 10.1038/nature21370.

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Jarvis DE, Ho YS, Lightfoot DJ, et al. Corrigendum: The genome of Chenopodium quinoa. Nature. 2017;545(7655):510doi: 10.1038/nature22384.
Jarvis, D. E., Ho, Y. S., Lightfoot, D. J., Schmöckel, S. M., Li, B., Borm, T. J. A., Ohyanagi, H., Mineta, K., Michell, C. T., Saber, N., Kharbatia, N. M., Rupper, R. R., Sharp, A. R., Dally, N., Boughton, B. A., Woo, Y. H., Gao, G., Schijlen, E. G. W. M., Guo, X., Momin, A. A., Negrão, S., Al-Babili, S., Gehring, C., Roessner, U., Jung, C., Murphy, K., Arold, S. T., Gojobori, T., van der Linden, C. G., van Loo, E. N., Jellen, E. N., Maughan, P. J., & Tester, M. (2017). Corrigendum: The genome of Chenopodium quinoa. Nature, 545(7655), 510. https://doi.org/10.1038/nature22384
Jarvis, David E, et al. "Corrigendum: The genome of Chenopodium quinoa." Nature vol. 545,7655 (2017): 510. doi: https://doi.org/10.1038/nature22384
Jarvis DE, Ho YS, Lightfoot DJ, Schmöckel SM, Li B, Borm TJA, Ohyanagi H, Mineta K, Michell CT, Saber N, Kharbatia NM, Rupper RR, Sharp AR, Dally N, Boughton BA, Woo YH, Gao G, Schijlen EGWM, Guo X, Momin AA, Negrão S, Al-Babili S, Gehring C, Roessner U, Jung C, Murphy K, Arold ST, Gojobori T, van der Linden CG, van Loo EN, Jellen EN, Maughan PJ, Tester M. Corrigendum: The genome of Chenopodium quinoa. Nature. 2017 May 25;545(7655):510. doi: 10.1038/nature22384. Epub 2017 May 10. PMID: 28489823.
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