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Showing 109 to 119 of 119 entries
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Risk communication as a core public health competence in infectious disease management: Development of the ECDC training curriculum and programme.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Dickmann P, Abraham T, Sarkar S, Wysocki P, Cecconi S, Apfel F, Nurm ÜK.
PMID: 27103616
Euro Surveill. 2016;21(14). doi: 10.2807/1560-7917.ES.2016.21.14.30188.

Risk communication has been identified as a core competence for guiding public health responses to infectious disease threats. The International Health Regulations (2005) call for all countries to build capacity and a comprehensive understanding of health risks before a...

Metal-Organic-Framework-Supported Molecular Electrocatalysis for the Oxygen Reduction Reaction.

Angewandte Chemie (International ed. in English)

Liang Z, Guo H, Zhou G, Guo K, Wang B, Lei H, Zhang W, Zheng H, Apfel UP, Cao R.
PMID: 33484092
Angew Chem Int Ed Engl. 2021 Apr 06;60(15):8472-8476. doi: 10.1002/anie.202016024. Epub 2021 Mar 03.

Synthesizing molecule@support hybrids is appealing to improve molecular electrocatalysis. We report herein metal-organic framework (MOF)-supported Co porphyrins for the oxygen reduction reaction (ORR) with improved activity and selectivity. Co porphyrins can be grafted on MOF surfaces through ligand exchange....

Local Surface Structure and Composition Control the Hydrogen Evolution Reaction on Iron Nickel Sulfides.

Angewandte Chemie (International ed. in English)

Bentley CL, Andronescu C, Smialkowski M, Kang M, Tarnev T, Marler B, Unwin PR, Apfel UP, Schuhmann W.
PMID: 29377499
Angew Chem Int Ed Engl. 2018 Apr 03;57(15):4093-4097. doi: 10.1002/anie.201712679. Epub 2018 Mar 09.

In order to design more powerful electrocatalysts, developing our understanding of the role of the surface structure and composition of widely abundant bulk materials is crucial. This is particularly true in the search for alternative hydrogen evolution reaction (HER)...

From Enzymes to Functional Materials-Towards Activation of Small Molecules.

Chemistry (Weinheim an der Bergstrasse, Germany)

Möller F, Piontek S, Miller RG, Apfel UP.
PMID: 28816379
Chemistry. 2018 Feb 01;24(7):1471-1493. doi: 10.1002/chem.201703451. Epub 2017 Nov 08.

The design of non-noble metal-containing heterogeneous catalysts for the activation of small molecules is of utmost importance for our society. While nature possesses very sophisticated machineries to perform such conversions, rationally designed catalytic materials are rare. Herein, we aim...

Synergistic Electrocatalytic Hydrogen Evolution in Ni/NiS Nanoparticles Wrapped in Multi-Heteroatom-Doped Reduced Graphene Oxide Nanosheets.

ACS applied materials & interfaces

Hegazy MBZ, Berber MR, Yamauchi Y, Pakdel A, Cao R, Apfel UP.
PMID: 34255483
ACS Appl Mater Interfaces. 2021 Jul 28;13(29):34043-34052. doi: 10.1021/acsami.1c05888. Epub 2021 Jul 13.

Hydrogen production is a key driver for sustainable and clean fuels used to generate electricity, which can be achieved through electrochemical splitting of water in alkaline solutions. However, the hydrogen evolution reaction (HER) is kinetically sluggish in alkaline media....

Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms.

ACS pharmacology & translational science

Apfel V, Begue D, Cordo' V, Holzer L, Martinuzzi L, Buhles A, Kerr G, Barbosa I, Naumann U, Piquet M, Ruddy D, Weiss A, Ferretti S, Almeida R, Bonenfant D, Tordella L, Galli GG.
PMID: 33615182
ACS Pharmacol Transl Sci. 2021 Jan 13;4(1):327-337. doi: 10.1021/acsptsci.0c00196. eCollection 2021 Feb 12.

Asparagine deprivation by l-asparaginase (L-ASNase) is an effective therapeutic strategy in acute lymphoblastic leukemia, with resistance occurring due to upregulation of ASNS, the only human enzyme synthetizing asparagine (

Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms.

ACS pharmacology & translational science

Apfel V, Begue D, Cordo' V, Holzer L, Martinuzzi L, Buhles A, Kerr G, Barbosa I, Naumann U, Piquet M, Ruddy D, Weiss A, Ferretti S, Almeida R, Bonenfant D, Tordella L, Galli GG.
PMID: 33615182
ACS Pharmacol Transl Sci. 2021 Jan 13;4(1):327-337. doi: 10.1021/acsptsci.0c00196. eCollection 2021 Feb 12.

Asparagine deprivation by l-asparaginase (L-ASNase) is an effective therapeutic strategy in acute lymphoblastic leukemia, with resistance occurring due to upregulation of ASNS, the only human enzyme synthetizing asparagine (

Introducing Water-Network-Assisted Proton Transfer for Boosted Electrocatalytic Hydrogen Evolution with Cobalt Corrole.

Angewandte Chemie (International ed. in English)

Li X, Lv B, Zhang XP, Jin X, Guo K, Zhou D, Bian H, Zhang W, Apfel UP, Cao R.
PMID: 34913230
Angew Chem Int Ed Engl. 2021 Dec 15;e202114310. doi: 10.1002/anie.202114310. Epub 2021 Dec 15.

Proton transfer is vital for many biological and chemical reactions. Hydrogen-bonded water-containing networks are often found in enzymes to assist proton transfer, but similar strategy has been rarely presented by synthetic catalysts. We herein report the Co corrole 1...

Successful Treatment of a Balamuthia mandrillaris Cerebral Abscess in a Pediatric Patient With Complete Surgical Resection and Antimicrobial Therapy.

The Pediatric infectious disease journal

Cuoco JA, Klein BJ, LeBel DP, Faulhaber J, Apfel LS, Witcher MR.
PMID: 34862343
Pediatr Infect Dis J. 2022 Feb 01;41(2):e54-e57. doi: 10.1097/INF.0000000000003418.

Cerebral amebic encephalitis due to Balamuthia mandrillaris is a rare yet typically fatal disease. As such, identification of the clinical characteristics, appropriate diagnostic workup and commencement of treatment is frequently delayed. Here, we present a case of a 4-year-old...

Reducing the racial achievement gap: A social-psychological intervention.

Science

Cohen G.L., Garcia J., Apfel N., Master A..
UIID-AC: 3
2006;313:1307-1310. doi: 10.1126/science.1128317.

Two randomized field experiments tested a social-psychological intervention designed to improve minority student performance and increase our understanding of how psychological threat mediates performance in chronically evaluative real-world environments. We expected that the risk of confirming a negative stereotype...

Recursive processes in self-affirmation: Intervening to close the minority achievement gap.

Science

Cohen G.L., Garcia J., Apfel N., Purdie-Vaughns V., Brzustoski P..
UIID-AC: 11
2009;324:400-403. doi: 10.1126/science.1170769.

A 2-year follow-up of a randomized field experiment previously reported in Science is presented. A subtle intervention to lessen minority students' psychological threat related to being negatively stereotyped in school was tested in an experiment conducted three times with...

Showing 109 to 119 of 119 entries