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Showing 1405 to 1414 of 1414 entries
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Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in .

Clinical cancer research : an official journal of the American Association for Cancer Research

Waldschmidt JM, Kloeber JA, Anand P, Frede J, Kokkalis A, Dimitrova V, Potdar S, Nair MS, Vijaykumar T, Im NG, Guillaumet-Adkins A, Chopra N, Stuart H, Budano L, Sotudeh N, Guo G, Grassberger C, Yee AJ, Laubach JP, Richardson PG, Anderson KC, Raje NS, Knoechel B, Lohr JG.
PMID: 34518309
Clin Cancer Res. 2021 Dec 01;27(23):6432-6444. doi: 10.1158/1078-0432.CCR-21-2040. Epub 2021 Sep 13.

PURPOSE: Although remarkably effective in some patients, precision medicine typically induces only transient responses despite initial absence of resistance-conferring mutations. Using EXPERIMENTAL DESIGN: Full-length single-cell RNA (scRNA) sequencing (scRNA-seq) was conducted on 3 patients with RESULTS: Profiling by scRNA-seq...

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Waldschmidt JM, Kloeber JA, Anand P, et al. Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in . Clin Cancer Res. 2021;27(23):6432-6444doi: 10.1158/1078-0432.CCR-21-2040.
Waldschmidt, J. M., Kloeber, J. A., Anand, P., Frede, J., Kokkalis, A., Dimitrova, V., Potdar, S., Nair, M. S., Vijaykumar, T., Im, N. G., Guillaumet-Adkins, A., Chopra, N., Stuart, H., Budano, L., Sotudeh, N., Guo, G., Grassberger, C., Yee, A. J., Laubach, J. P., Richardson, P. G., Anderson, K. C., Raje, N. S., Knoechel, B., & Lohr, J. G. (2021). Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in . Clinical cancer research : an official journal of the American Association for Cancer Research, 27(23), 6432-6444. https://doi.org/10.1158/1078-0432.CCR-21-2040
Waldschmidt, Johannes M, et al. "Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in ." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 27,23 (2021): 6432-6444. doi: https://doi.org/10.1158/1078-0432.CCR-21-2040
Waldschmidt JM, Kloeber JA, Anand P, Frede J, Kokkalis A, Dimitrova V, Potdar S, Nair MS, Vijaykumar T, Im NG, Guillaumet-Adkins A, Chopra N, Stuart H, Budano L, Sotudeh N, Guo G, Grassberger C, Yee AJ, Laubach JP, Richardson PG, Anderson KC, Raje NS, Knoechel B, Lohr JG. Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in . Clin Cancer Res. 2021 Dec 01;27(23):6432-6444. doi: 10.1158/1078-0432.CCR-21-2040. Epub 2021 Sep 13. PMID: 34518309; PMCID: PMC8639639.
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Mapping autonomic, mood and cognitive effects of hypothalamic region deep brain stimulation.

Brain : a journal of neurology

Neudorfer C, Elias GJB, Jakobs M, Boutet A, Germann J, Narang K, Loh A, Paff M, Horn A, Kucharczyk W, Deeb W, Salvato B, Almeida L, Foote KD, Rosenberg PB, Tang-Wai DF, Anderson WS, Mari Z, Ponce FA, Wolk DA, Burke AD, Salloway S, Sabbagh MN, Chakravarty MM, Smith GS, Lyketsos CG, Okun MS, Lozano AM.
PMID: 33905474
Brain. 2021 Oct 22;144(9):2837-2851. doi: 10.1093/brain/awab170.

Because of its involvement in a wide variety of cardiovascular, metabolic and behavioural functions, the hypothalamus constitutes a potential target for neuromodulation in a number of treatment-refractory conditions. The precise neural substrates and circuitry subserving these responses, however, are...

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Neudorfer C, Elias GJB, Jakobs M, et al. Mapping autonomic, mood and cognitive effects of hypothalamic region deep brain stimulation. Brain. 2021;144(9):2837-2851doi: 10.1093/brain/awab170.
Neudorfer, C., Elias, G. J. B., Jakobs, M., Boutet, A., Germann, J., Narang, K., Loh, A., Paff, M., Horn, A., Kucharczyk, W., Deeb, W., Salvato, B., Almeida, L., Foote, K. D., Rosenberg, P. B., Tang-Wai, D. F., Anderson, W. S., Mari, Z., Ponce, F. A., Wolk, D. A., Burke, A. D., Salloway, S., Sabbagh, M. N., Chakravarty, M. M., Smith, G. S., Lyketsos, C. G., Okun, M. S., & Lozano, A. M. (2021). Mapping autonomic, mood and cognitive effects of hypothalamic region deep brain stimulation. Brain : a journal of neurology, 144(9), 2837-2851. https://doi.org/10.1093/brain/awab170
Neudorfer, Clemens, et al. "Mapping autonomic, mood and cognitive effects of hypothalamic region deep brain stimulation." Brain : a journal of neurology vol. 144,9 (2021): 2837-2851. doi: https://doi.org/10.1093/brain/awab170
Neudorfer C, Elias GJB, Jakobs M, Boutet A, Germann J, Narang K, Loh A, Paff M, Horn A, Kucharczyk W, Deeb W, Salvato B, Almeida L, Foote KD, Rosenberg PB, Tang-Wai DF, Anderson WS, Mari Z, Ponce FA, Wolk DA, Burke AD, Salloway S, Sabbagh MN, Chakravarty MM, Smith GS, Lyketsos CG, Okun MS, Lozano AM. Mapping autonomic, mood and cognitive effects of hypothalamic region deep brain stimulation. Brain. 2021 Oct 22;144(9):2837-2851. doi: 10.1093/brain/awab170. PMID: 33905474; PMCID: PMC8557336.
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Rapid, Large-Scale Wastewater Surveillance and Automated Reporting System Enable Early Detection of Nearly 85% of COVID-19 Cases on a University Campus.

mSystems

Karthikeyan S, Nguyen A, McDonald D, Zong Y, Ronquillo N, Ren J, Zou J, Farmer S, Humphrey G, Henderson D, Javidi T, Messer K, Anderson C, Schooley R, Martin NK, Knight R.
PMID: 34374562
mSystems. 2021 Aug 31;6(4):e0079321. doi: 10.1128/mSystems.00793-21. Epub 2021 Aug 10.

Wastewater-based surveillance has gained prominence and come to the forefront as a leading indicator of forecasting COVID-19 (coronavirus disease 2019) infection dynamics owing to its cost-effectiveness and its ability to inform early public health interventions. A university campus could...

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Karthikeyan S, Nguyen A, McDonald D, et al. Rapid, Large-Scale Wastewater Surveillance and Automated Reporting System Enable Early Detection of Nearly 85% of COVID-19 Cases on a University Campus. mSystems. 2021;6(4):e0079321doi: 10.1128/mSystems.00793-21.
Karthikeyan, S., Nguyen, A., McDonald, D., Zong, Y., Ronquillo, N., Ren, J., Zou, J., Farmer, S., Humphrey, G., Henderson, D., Javidi, T., Messer, K., Anderson, C., Schooley, R., Martin, N. K., & Knight, R. (2021). Rapid, Large-Scale Wastewater Surveillance and Automated Reporting System Enable Early Detection of Nearly 85% of COVID-19 Cases on a University Campus. mSystems, 6(4), e0079321. https://doi.org/10.1128/mSystems.00793-21
Karthikeyan, Smruthi, et al. "Rapid, Large-Scale Wastewater Surveillance and Automated Reporting System Enable Early Detection of Nearly 85% of COVID-19 Cases on a University Campus." mSystems vol. 6,4 (2021): e0079321. doi: https://doi.org/10.1128/mSystems.00793-21
Karthikeyan S, Nguyen A, McDonald D, Zong Y, Ronquillo N, Ren J, Zou J, Farmer S, Humphrey G, Henderson D, Javidi T, Messer K, Anderson C, Schooley R, Martin NK, Knight R. Rapid, Large-Scale Wastewater Surveillance and Automated Reporting System Enable Early Detection of Nearly 85% of COVID-19 Cases on a University Campus. mSystems. 2021 Aug 31;6(4):e0079321. doi: 10.1128/mSystems.00793-21. Epub 2021 Aug 10. PMID: 34374562; PMCID: PMC8409724.
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Large Cell Calcifying Sertoli Cell Tumour: A Contemporary Multi-Institutional Case Series Highlighting the Diagnostic Utility of PRKAR1A Immunohistochemistry.

Histopathology

Anderson WJ, Gordetsky JB, Idrees MT, Al-Obaidy KI, Kao CS, Cornejo KM, Wobker SE, Cheville JC, Vargas SO, Fletcher CDM, Hirsch MS, Acosta AM.
PMID: 34780072
Histopathology. 2021 Nov 15; doi: 10.1111/his.14599. Epub 2021 Nov 15.

AIMS: Large cell calcifying Sertoli cell tumour (LCCSCT) is a rare testicular sex cord-stromal tumour that primarily affects young patients and is associated with Carney complex. We sought to characterize the clinicopathological features of a series of LCCSCT and...

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Anderson WJ, Gordetsky JB, Idrees MT, et al. Large Cell Calcifying Sertoli Cell Tumour: A Contemporary Multi-Institutional Case Series Highlighting the Diagnostic Utility of PRKAR1A Immunohistochemistry. Histopathology. 2021;doi: 10.1111/his.14599.
Anderson, W. J., Gordetsky, J. B., Idrees, M. T., Al-Obaidy, K. I., Kao, C. S., Cornejo, K. M., Wobker, S. E., Cheville, J. C., Vargas, S. O., Fletcher, C. D. M., Hirsch, M. S., & Acosta, A. M. (2021). Large Cell Calcifying Sertoli Cell Tumour: A Contemporary Multi-Institutional Case Series Highlighting the Diagnostic Utility of PRKAR1A Immunohistochemistry. Histopathology, . https://doi.org/10.1111/his.14599
Anderson, William J, et al. "Large Cell Calcifying Sertoli Cell Tumour: A Contemporary Multi-Institutional Case Series Highlighting the Diagnostic Utility of PRKAR1A Immunohistochemistry." Histopathology vol. (2021). doi: https://doi.org/10.1111/his.14599
Anderson WJ, Gordetsky JB, Idrees MT, Al-Obaidy KI, Kao CS, Cornejo KM, Wobker SE, Cheville JC, Vargas SO, Fletcher CDM, Hirsch MS, Acosta AM. Large Cell Calcifying Sertoli Cell Tumour: A Contemporary Multi-Institutional Case Series Highlighting the Diagnostic Utility of PRKAR1A Immunohistochemistry. Histopathology. 2021 Nov 15; doi: 10.1111/his.14599. Epub 2021 Nov 15. PMID: 34780072.
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BCMA-Specific ADC MEDI2228 and Daratumumab Induce Synergistic Myeloma Cytotoxicity via IFN-Driven Immune Responses and Enhanced CD38 Expression.

Clinical cancer research : an official journal of the American Association for Cancer Research

Xing L, Wang S, Liu J, Yu T, Chen H, Wen K, Li Y, Lin L, Hsieh PA, Cho SF, An G, Qiu L, Kinneer K, Munshi N, Anderson KC, Tai YT.
PMID: 34301753
Clin Cancer Res. 2021 Jul 23; doi: 10.1158/1078-0432.CCR-21-1621. Epub 2021 Jul 23.

PURPOSE: Efforts are required to improve the potency and durability of CD38- and BCMA-based immunotherapies in human multiple myeloma. We here delineated the molecular and cellular mechanisms underlying novel immunomodulatory effects triggered by BCMA pyrrolobenzodiazepine (PBD) antibody drug conjugate...

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Xing L, Wang S, Liu J, et al. BCMA-Specific ADC MEDI2228 and Daratumumab Induce Synergistic Myeloma Cytotoxicity via IFN-Driven Immune Responses and Enhanced CD38 Expression. Clin Cancer Res. 2021;doi: 10.1158/1078-0432.CCR-21-1621.
Xing, L., Wang, S., Liu, J., Yu, T., Chen, H., Wen, K., Li, Y., Lin, L., Hsieh, P. A., Cho, S. F., An, G., Qiu, L., Kinneer, K., Munshi, N., Anderson, K. C., & Tai, Y. T. (2021). BCMA-Specific ADC MEDI2228 and Daratumumab Induce Synergistic Myeloma Cytotoxicity via IFN-Driven Immune Responses and Enhanced CD38 Expression. Clinical cancer research : an official journal of the American Association for Cancer Research, . https://doi.org/10.1158/1078-0432.CCR-21-1621
Xing, Lijie, et al. "BCMA-Specific ADC MEDI2228 and Daratumumab Induce Synergistic Myeloma Cytotoxicity via IFN-Driven Immune Responses and Enhanced CD38 Expression." Clinical cancer research : an official journal of the American Association for Cancer Research vol. (2021). doi: https://doi.org/10.1158/1078-0432.CCR-21-1621
Xing L, Wang S, Liu J, Yu T, Chen H, Wen K, Li Y, Lin L, Hsieh PA, Cho SF, An G, Qiu L, Kinneer K, Munshi N, Anderson KC, Tai YT. BCMA-Specific ADC MEDI2228 and Daratumumab Induce Synergistic Myeloma Cytotoxicity via IFN-Driven Immune Responses and Enhanced CD38 Expression. Clin Cancer Res. 2021 Jul 23; doi: 10.1158/1078-0432.CCR-21-1621. Epub 2021 Jul 23. PMID: 34301753.
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Why has the incidence of tuberculosis not reduced in London during the COVID-19 pandemic?.

The Lancet. Respiratory medicine

Lewer D, Mulchandani R, Roche A, Cosgrove C, Anderson C.
PMID: 35032431
Lancet Respir Med. 2022 Jan 12; doi: 10.1016/S2213-2600(22)00012-1. Epub 2022 Jan 12.

No abstract available.

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Lewer D, Mulchandani R, Roche A, et al. Why has the incidence of tuberculosis not reduced in London during the COVID-19 pandemic?. Lancet Respir Med. 2022;doi: 10.1016/S2213-2600(22)00012-1.
Lewer, D., Mulchandani, R., Roche, A., Cosgrove, C., & Anderson, C. (2022). Why has the incidence of tuberculosis not reduced in London during the COVID-19 pandemic?. The Lancet. Respiratory medicine, . https://doi.org/10.1016/S2213-2600(22)00012-1
Lewer, Dan, et al. "Why has the incidence of tuberculosis not reduced in London during the COVID-19 pandemic?." The Lancet. Respiratory medicine vol. (2022). doi: https://doi.org/10.1016/S2213-2600(22)00012-1
Lewer D, Mulchandani R, Roche A, Cosgrove C, Anderson C. Why has the incidence of tuberculosis not reduced in London during the COVID-19 pandemic?. Lancet Respir Med. 2022 Jan 12; doi: 10.1016/S2213-2600(22)00012-1. Epub 2022 Jan 12. PMID: 35032431.
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Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial.

BMC emergency medicine

Tunnage B, Woodhouse LJ, Dixon M, Anderson C, Ankolekar S, Appleton J, Cala L, England T, Krishnan K, Havard D, Mair G, Muir K, Phillips S, Potter J, Price C, Randall M, Robinson TG, Roffe C, Sandset E, Siriwardena N, Scutt P, Wardlaw JM, Sprigg N, Bath PM.
PMID: 35012462
BMC Emerg Med. 2022 Jan 10;22(1):2. doi: 10.1186/s12873-021-00560-x.

BACKGROUND: Prehospital stroke trials will inevitably recruit patients with non-stroke conditions, so called stroke mimics. We undertook a pre-specified analysis to determine outcomes in patients with mimics in the second Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial...

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Tunnage B, Woodhouse LJ, Dixon M, et al. Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial. BMC Emerg Med. 2022;22(1):2doi: 10.1186/s12873-021-00560-x.
Tunnage, B., Woodhouse, L. J., Dixon, M., Anderson, C., Ankolekar, S., Appleton, J., Cala, L., England, T., Krishnan, K., Havard, D., Mair, G., Muir, K., Phillips, S., Potter, J., Price, C., Randall, M., Robinson, T. G., Roffe, C., Sandset, E., Siriwardena, N., Scutt, P., Wardlaw, J. M., Sprigg, N., Bath, P. M. (2022). Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial. BMC emergency medicine, 22(1), 2. https://doi.org/10.1186/s12873-021-00560-x
Tunnage, Bronwyn, et al. "Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial." BMC emergency medicine vol. 22,1 (2022): 2. doi: https://doi.org/10.1186/s12873-021-00560-x
Tunnage B, Woodhouse LJ, Dixon M, Anderson C, Ankolekar S, Appleton J, Cala L, England T, Krishnan K, Havard D, Mair G, Muir K, Phillips S, Potter J, Price C, Randall M, Robinson TG, Roffe C, Sandset E, Siriwardena N, Scutt P, Wardlaw JM, Sprigg N, Bath PM. Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial. BMC Emerg Med. 2022 Jan 10;22(1):2. doi: 10.1186/s12873-021-00560-x. PMID: 35012462; PMCID: PMC8744321.
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The Role of Scientific Communication Skills in Trainees' Intention to Pursue Biomedical Research Careers: A Social Cognitive Analysis.

Chang S, Byars-Winston A, Cameron C, Baldwin CD, Lee HY, Anderson C.
UIID-AD: 3836
2015; doi: 10.1187/cbe.14-09-0152.

Scientific communication (SciComm) skills are indispensable for success in biomedical research, but many trainees may not have fully considered the necessity of regular writing and speaking for research career progression. Our purpose was to investigate the relationship between SciComm...

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Chang S, Byars-Winston A, Cameron C, et al. The Role of Scientific Communication Skills in Trainees' Intention to Pursue Biomedical Research Careers: A Social Cognitive Analysis. 2015;doi: 10.1187/cbe.14-09-0152.
Chang, S., Byars-Winston, A., Cameron, C., Baldwin, C. D., Lee, H. Y., & Anderson, C. (2015). The Role of Scientific Communication Skills in Trainees' Intention to Pursue Biomedical Research Careers: A Social Cognitive Analysis. . https://doi.org/10.1187/cbe.14-09-0152
Chang, S, et al. "The Role of Scientific Communication Skills in Trainees' Intention to Pursue Biomedical Research Careers: A Social Cognitive Analysis." vol. (2015). doi: https://doi.org/10.1187/cbe.14-09-0152
Chang S, Byars-Winston A, Cameron C, Baldwin CD, Lee HY, Anderson C. The Role of Scientific Communication Skills in Trainees' Intention to Pursue Biomedical Research Careers: A Social Cognitive Analysis. 2015; doi: 10.1187/cbe.14-09-0152. UIID-AD: 3836.
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Providing premedical students with quality clinical and research experience: the Tobacco Science Scholars Program.

Davis JM, Anderson MC, Stankevitz KA, Manley AR.
UIID-AD: 2694
2013;112:195-8.

Undergraduate premedical students face a formidable decision as they work to determine whether to pursue a profession in medicine. Exposure to clinical medicine and research is essential to inform students what it might be like to be a physician....

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Davis JM, Anderson MC, Stankevitz KA, et al. Providing premedical students with quality clinical and research experience: the Tobacco Science Scholars Program. 2013;112:195-8
Davis, J. M., Anderson, M. C., Stankevitz, K. A., & Manley, A. R. (2013). Providing premedical students with quality clinical and research experience: the Tobacco Science Scholars Program. 112195-8.
Davis, J M, et al. "Providing premedical students with quality clinical and research experience: the Tobacco Science Scholars Program." vol. 112 (2013): 195-8.
Davis JM, Anderson MC, Stankevitz KA, Manley AR. Providing premedical students with quality clinical and research experience: the Tobacco Science Scholars Program. 2013;112:195-8. UIID-AD: 2694.
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Gender, technology use and ownership, and media-based multitasking among middle school students.

Cotten SR, Shank DB, Anderson WA.
UIID-AD: 951
2014;35:99-106. doi: 10.1016/j.chb.2014.02.041.

We propose and test a new explanation for why more girls than boys multitask with media. We argue that gender differences in technology use and ownership function as the proximal cause for these gender differences in media multitasking. Prior...

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Cotten SR, Shank DB, Anderson WA. Gender, technology use and ownership, and media-based multitasking among middle school students. 2014;35:99-106doi: 10.1016/j.chb.2014.02.041.
Cotten, S. R., Shank, D. B., & Anderson, W. A. (2014). Gender, technology use and ownership, and media-based multitasking among middle school students. 3599-106. https://doi.org/10.1016/j.chb.2014.02.041
Cotten, S R, et al. "Gender, technology use and ownership, and media-based multitasking among middle school students." vol. 35 (2014): 99-106. doi: https://doi.org/10.1016/j.chb.2014.02.041
Cotten SR, Shank DB, Anderson WA. Gender, technology use and ownership, and media-based multitasking among middle school students. 2014;35:99-106. doi: 10.1016/j.chb.2014.02.041. UIID-AD: 951.
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Showing 1405 to 1414 of 1414 entries