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Showing 2545 to 2556 of 2570 entries
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Colonization of fecal microbiota from patients with neonatal necrotizing enterocolitis exacerbates intestinal injury in germfree mice subjected to necrotizing enterocolitis-induction protocol via alterations in butyrate and regulatory T cells.

Journal of translational medicine

He Y, Du W, Xiao S, Zeng B, She X, Liu D, Du H, Li L, Li F, Ai Q, He J, Song C, Wei H, Zhao X, Yu J.
PMID: 34922582
J Transl Med. 2021 Dec 18;19(1):510. doi: 10.1186/s12967-021-03109-5.

BACKGROUND: Necrotizing enterocolitis (NEC) remains a life-threatening disease in neonates. Numerous studies have shown a correlation between the intestinal microbiota and NEC, but the causal link remains unclear. This study aimed to demonstrate the causal role of gut microbiota...

Potential Strategies to Improve the Effectiveness of Drug Therapy by Changing Factors Related to Tumor Microenvironment.

Frontiers in cell and developmental biology

Cao D, Naiyila X, Li J, Huang Y, Chen Z, Chen B, Li J, Guo J, Dong Q, Ai J, Yang L, Liu L, Wei Q.
PMID: 34447750
Front Cell Dev Biol. 2021 Aug 10;9:705280. doi: 10.3389/fcell.2021.705280. eCollection 2021.

A tumor microenvironment (TME) is composed of various cell types and extracellular components. It contains tumor cells and is nourished by a network of blood vessels. The TME not only plays a significant role in the occurrence, development, and...

Polysorbate-80 pretreatment contributing to volatile fatty acids production associated microbial interactions via acidogenic fermentation of waste activated sludge.

Bioresource technology

Ai X, Xin X, Wei W, Xie J, Hong J.
PMID: 34871722
Bioresour Technol. 2021 Dec 03;345:126488. doi: 10.1016/j.biortech.2021.126488. Epub 2021 Dec 03.

Polyoxyethylene dehydration sorbitol monooleate (polysorbate-80) pretreatment enhanced volatile fatty acids (VFAs) production of waste activated sludge (WAS) in acidogenic fermentation. The results showed that polysorbate-80 ameliorated WAS solubilization obviously with a soluble chemical oxygen demand (SCOD) increasing to 1536...

C1q/TNF-related protein 9 decreases cardiomyocyte hypoxia/reoxygenation-induced inflammation by inhibiting the TLR4/MyD88/NF-κB signaling pathway.

Experimental and therapeutic medicine

Huang Z, Zhao D, Wang Y, Li X, Li J, Han J, Jiang L, Ai F, Zhou Z.
PMID: 34504585
Exp Ther Med. 2021 Oct;22(4):1139. doi: 10.3892/etm.2021.10573. Epub 2021 Aug 08.

C1q/TNF-related protein 9 (CTRP9) acts as an adipokine and has been reported to exert numerous biological functions, such as anti-inflammatory and anti-oxidative stress effects, in ischemic heart disease. In the present study, the role of CTRP9 in neonatal rat...

Energy-Saving Optimization and Control of Autonomous Electric Vehicles With Considering Multiconstraints.

IEEE transactions on cybernetics

Zhang Y, Ai Z, Chen J, You T, Du C, Deng L.
PMID: 33872179
IEEE Trans Cybern. 2021 Apr 19; doi: 10.1109/TCYB.2021.3069674. Epub 2021 Apr 19.

The energy utilization efficiency of autonomous electric vehicles is seriously affected by the longitudinal motion control performance. However, the longitudinal motion control is constrained by the driving scene. This article proposes an energy-saving optimization and control (ESOC) method to...

Characterisation of bone regeneration in 3D printed ductile PCL/PEG/hydroxyapatite scaffolds with high ceramic microparticle concentrations.

Biomaterials science

Cao C, Huang P, Prasopthum A, Parsons AJ, Ai F, Yang J.
PMID: 34806738
Biomater Sci. 2021 Dec 21;10(1):138-152. doi: 10.1039/d1bm01645h.

3D printed bioactive glass or bioceramic particle reinforced composite scaffolds for bone tissue engineering currently suffer from low particle concentration (100% breaking strain) by adding poly(ethylene glycol) which is biocompatible and FDA approved. The scaffolds require no post-printing washing...

Pulmonary vascular system: A vulnerable target for COVID-19.

MedComm

Ai J, Hong W, Wu M, Wei X.
PMID: 34909758
MedComm (2020). 2021 Oct 17; doi: 10.1002/mco2.94. Epub 2021 Oct 17.

The number of coronavirus disease 2019 (COVID-19) cases has been increasing significantly, and the disease has evolved into a global pandemic, posing an unprecedented challenge to the healthcare community. Angiotensin-converting enzyme 2, the binding and entry receptor of severe...

Nutraceutical potentials of algal ulvan for healthy aging.

International journal of biological macromolecules

Liu D, Ouyang Y, Chen R, Wang M, Ai C, El-Seedi HR, Sarker MMR, Chen X, Zhao C.
PMID: 34826453
Int J Biol Macromol. 2022 Jan 01;194:422-434. doi: 10.1016/j.ijbiomac.2021.11.084. Epub 2021 Nov 24.

Several theories for aging are constantly put forth to explain the underlying mechanisms. Oxidative stress, DNA dysfunction, inflammation, and mitochondrial dysfunction, along with the release of cytochrome c are some of these theories. Diseases such as type 2 diabetes...

The Distinct Immune Nature of the Fetal Inflammatory Response Syndrome Type I and Type II.

ImmunoHorizons

Para R, Romero R, Miller D, Galaz J, Done B, Peyvandipour A, Gershater M, Tao L, Motomura K, Ruden DM, Isherwood J, Jung E, Kanninen T, Pique-Regi R, Tarca AL, Gomez-Lopez N.
PMID: 34521696
Immunohorizons. 2021 Sep 14;5(9):735-751. doi: 10.4049/immunohorizons.2100047.

Fetal inflammatory response syndrome (FIRS) is strongly associated with neonatal morbidity and mortality and can be classified as type I or type II. Clinically, FIRS type I and type II are considered as distinct syndromes, yet the molecular underpinnings...

Alteration of Gut Microbiota Relates to Metabolic Disorders in Primary Aldosteronism Patients.

Frontiers in endocrinology

Liu Y, Jiang Q, Liu Z, Shen S, Ai J, Zhu Y, Zhou L.
PMID: 34484110
Front Endocrinol (Lausanne). 2021 Aug 17;12:667951. doi: 10.3389/fendo.2021.667951. eCollection 2021.

PURPOSE: This study aimed to determine the relationships among gut microbiota, primary aldosteronism (PA), and related metabolic disorders.METHODS: The study enrolled 13 PA patients, 26 sex-matched primary hypertension patients, and 26 sex-matched healthy controls. Demographic and clinical characteristics such...

Changes in the hepatic differentiation potential of human mesenchymal stem cells aged .

Annals of translational medicine

Luo S, Xiao S, Ai Y, Wang B, Wang Y.
PMID: 34926672
Ann Transl Med. 2021 Nov;9(21):1628. doi: 10.21037/atm-21-4918.

BACKGROUND: Due to their multipotency and ability for self-renewal, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) hold great promise for generating hepatocytes. Previous research has successfully generated hepatocytes from early-passage [i.e., passage (P)3] hUC-MSCs; however, the populations of early-passage...

Hippo/yes-associated protein signaling functions as a mechanotransducer in regulating vascular homeostasis.

Journal of molecular and cellular cardiology

Lv H, Ai D.
PMID: 34547259
J Mol Cell Cardiol. 2021 Sep 20;162:158-165. doi: 10.1016/j.yjmcc.2021.09.007. Epub 2021 Sep 20.

Cells are constantly exposed to various mechanical forces, including hydrostatic pressure, cyclic stretch, fluid shear stress, and extracellular matrix stiffness. Mechanical cues can be translated into the cell-specific transcriptional process by a cellular mechanic-transducer. Evidence suggests that mechanical signals...

Showing 2545 to 2556 of 2570 entries