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Assessment of drug-drug interactions of CC-90001, a potent and selective inhibitor of c-Jun N-terminal kinase.

Xenobiotica; the fate of foreign compounds in biological systems

Tong Z, Gaudy A, Tatosian D, Ramirez-Valle F, Liu H, Chen J, Hoffmann M, Surapaneni S.
PMID: 35000550
Xenobiotica. 2022 Jan 13;1-11. doi: 10.1080/00498254.2022.2027553. Epub 2022 Jan 13.

CC-90001 is predominantly metabolised via glucuronidation, while oxidative metabolism is a minor pathway in human hepatocytes and liver microsomes.

Showing 73 to 73 of 73 entries