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Correction.

Xenobiotica; the fate of foreign compounds in biological systems

[No authors listed]
PMID: 32151212
Xenobiotica. 2020 May;50(5):620. doi: 10.1080/00498254.2019.1639934. Epub 2019 Aug 30.

No abstract available.

Correction to: Cassidy et al., Disposition and metabolism of [.

Xenobiotica; the fate of foreign compounds in biological systems

[No authors listed]
PMID: 29405089
Xenobiotica. 2018 Apr;48(4):x-xi. doi: 10.1080/00498254.2018.1436416.

No abstract available.

Interaction of green tea catechins with renal organic cation transporter 2.

Xenobiotica; the fate of foreign compounds in biological systems

Jaiyen C, Jutabha P, Anzai N, Lungkaphin A, Soodvilai S, Srimaroeng C.
PMID: 26576923
Xenobiotica. 2016 Jul;46(7):641-650. doi: 10.3109/00498254.2015.1107785. Epub 2015 Nov 17.

1. Green tea extract (GTE) and EGCG have previously shown to increase the uptake of MPP

Effect of long-term coadministration of compound glycyrrhizin tablets on the pharmacokinetics of mycophenolic acid in rats.

Xenobiotica; the fate of foreign compounds in biological systems

Liu Q, Jiao Z, Zhong M, Zhang M, Geng F, Zhao H.
PMID: 26522231
Xenobiotica. 2016 Jul;46(7):627-633. doi: 10.3109/00498254.2015.1103386. Epub 2015 Nov 02.

1. Mycophenolic acid (MPA), having high-protein affinity, is an immunodepressant and the genuine-active ingredient of enteric-coated mycophenolate sodium (EC-MPS) tablet that has been widely used in combination with tacrolimus or cyclosporine to prevent acute rejection after organ transplantation. Moreover,...

Sulfation of 6-hydroxymelatonin, N-acetylserotonin and 4-hydroxyramelteon by the human cytosolic sulfotransferases (SULTs).

Xenobiotica; the fate of foreign compounds in biological systems

Luo L, Zhou C, Kurogi K, Sakakibara Y, Suiko M, Liu MC.
PMID: 26577053
Xenobiotica. 2016 Jul;46(7):612-619. doi: 10.3109/00498254.2015.1107656. Epub 2015 Nov 17.

1. This study aimed to investigate the involvement of sulfation in the metabolism of 6-hydroxymelatonin (6-OH-Mel), N-acetylserotonin (NAS) and 4-hydroxyramelteon (4-OH-Ram), and to identify and characterize the human cytosolic sulfotransferases (SULTs) capable of sulfating these drug compounds. 2. A...

Species and tissue differences in serotonin glucuronidation.

Xenobiotica; the fate of foreign compounds in biological systems

Sakakibara Y, Katoh M, Kawayanagi T, Nadai M.
PMID: 26526550
Xenobiotica. 2016 Jul;46(7):605-611. doi: 10.3109/00498254.2015.1101509. Epub 2015 Nov 02.

1. Serotonin is a UGT1A6 substrate that is mainly found in the extrahepatic tissues where some UGT1As are expressed. The aim of the present study was to characterize serotonin glucuronidation in various tissues of humans and rodents. 2. Serotonin...

Commentary concerning the publication by Zheng X et al.: Metabolic activation of deferiprone mediated by CYP2A6 (Xenobiotica, published online 18 May 2021).

Xenobiotica; the fate of foreign compounds in biological systems

Tricta F.
PMID: 34596004
Xenobiotica. 2021 Oct 06;1-2. doi: 10.1080/00498254.2021.1986650. Epub 2021 Oct 06.

No abstract available.

Xenobiotica; the fate of foreign compounds in biological systems

Säll C, Fogt Hjorth C.
PMID: 34913834
Xenobiotica. 2021 Dec 16;1-54. doi: 10.1080/00498254.2021.2018628. Epub 2021 Dec 16.

1. NDec is a novel, oral, fixed dose formulation of decitabine and tetrahydrouridine that is currently being developed for the treatment of patients with sickle cell disease. Here, we examine the potential for both components of NDec to interact...

Evaluation of MTBH, a novel hesperetin derivative, on the activity of hepatic cytochrome P450 isoform .

Xenobiotica; the fate of foreign compounds in biological systems

Qin Y, Dong H, Sun J, Zhang Y, Li J, Zhang T, Chen G, Wang S, Song S, Wang W, Fan Y, Wang J, Huang X, Shen C.
PMID: 34806938
Xenobiotica. 2022 Jan 03;1-11. doi: 10.1080/00498254.2021.2009934. Epub 2022 Jan 03.

1. 8-methylene-tert-butylamine-3',5,7-trihydroxy-4'-methoxyflavanone (MTBH), a novel hesperidin derivative, has potential in the prevention of hepatic disease, however, its effects on cytochrome P450 isoforms (CYP450s) remains unexplored. The purpose was to investigate the effects of MTBH on the mRNA, protein levels,...

Agrimoniin inhibits the activity of CYP1A2, 2D6, and 3A4 in human liver microsomes.

Xenobiotica; the fate of foreign compounds in biological systems

Zhou Y, Xian Q, Wei H, Zhou J, Li S, Yang J, Zhou X, Li Y.
PMID: 34806927
Xenobiotica. 2021 Nov 28;1-6. doi: 10.1080/00498254.2021.2009592. Epub 2021 Nov 28.

The effect of agrimoniin on the activity of cytochrome P450 (CYP450) enzymes would induce drug-drug interaction, which leads to adverse effects or even failure of therapy.Agrimoniin was incubated with the specific substrates of eight human liver CYP isoforms in...

Evaluation of MTBH, a novel hesperetin derivative, on the activity of hepatic cytochrome P450 isoform .

Xenobiotica; the fate of foreign compounds in biological systems

Qin Y, Dong H, Sun J, Zhang Y, Li J, Zhang T, Chen G, Wang S, Song S, Wang W, Fan Y, Wang J, Huang X, Shen C.
PMID: 34806938
Xenobiotica. 2021 Nov 22;1-14. doi: 10.1080/00498254.2021.2009934. Epub 2021 Nov 22.

8-methylene-tert-butylamine-3',5,7-trihydroxy-4'-methoxyflavanone (MTBH), a novel hesperidin derivative, has potential in the prevention of hepatic disease, however, its effects on cytochrome P450 isoforms (P450s) remains unexplored. The purpose was to investigate the effects of MTBH on the mRNA, protein levels and...

Xenobiotica; the fate of foreign compounds in biological systems

Fagerholm U, Hellberg S, Alvarsson J, Arvidsson McShane S, Spjuth O.
PMID: 34845977
Xenobiotica. 2021 Dec 08;1-6. doi: 10.1080/00498254.2021.2011471. Epub 2021 Dec 08.

Volume of distribution at steady state (V

Showing 13 to 24 of 73 entries