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Showing 25 to 36 of 339 entries
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Pancreatic neuroendocrine tumors: approach to treatment with focus on sunitinib.

Therapeutic advances in gastroenterology

Vinik AI, Raymond E.
PMID: 24003340
Therap Adv Gastroenterol. 2013 Sep;6(5):396-411. doi: 10.1177/1756283X13493878.

Pancreatic neuroendocrine tumors (pNETs) are relatively rare malignancies. With secretory tumors such as insulinomas, vasoactive intestinal peptideomas, and gastrinomas, the hormone produced causes the symptom complex (e.g. hypoglycemia, peptic ulcer disease). With nonsecretory NETs, the clinical condition is determined...

Effect of miRNA-19a on gastrointestinal motility in rats with functional dyspepsia.

Experimental and therapeutic medicine

Deng Y, Zhou X, Xiang X, Ou Y, He J.
PMID: 29805508
Exp Ther Med. 2018 Jun;15(6):4875-4879. doi: 10.3892/etm.2018.6009. Epub 2018 Mar 30.

The effect of microRNA (miRNA)-19a on gastrointestinal motility in rats with functional dyspepsia was investigated. Fifty adult Sprague-Dawley (SD) rats were randomly divided into 5 groups, 10 rats in each group, one group as the normal group, one group...

Is compensatory hyperhidrosis after thoracic sympathicotomy in palmar hyperhidrosis patients related to the excitability of thoracic sympathetic ganglions?.

Journal of thoracic disease

Chen JP, Chen RF, Peng AJ, Xu CH, Li GY.
PMID: 29221281
J Thorac Dis. 2017 Sep;9(9):3069-3075. doi: 10.21037/jtd.2017.08.100.

BACKGROUND: The mechanism of compensatory hyperhidrosis remains unclear. The aim of this study was to explore the relationship between compensatory hyperhidrosis and thoracic sympathetic ganglion excitability to assess the effectiveness of thoracoscopic T4 sympathicotomy for treating palmar hyperhidrosis.METHODS: Sixty-six...

Enhanced Mortality to Metastatic Bladder Cancer Cell Line MB49 in Vasoactive Intestinal Peptide Gene Knockout Mice.

Frontiers in endocrinology

Mirsaidi N, Burns MP, McClain SA, Forsyth E, Li J, Dukes B, Lin D, Nahvi R, Giraldo J, Patton M, Wang P, Lin K, Miller E, Ratliff T, Hamidi S, Crist S, Takemaru KI, Szema A.
PMID: 28824540
Front Endocrinol (Lausanne). 2017 Aug 07;8:162. doi: 10.3389/fendo.2017.00162. eCollection 2017.

To identify if the absence of the vasoactive intestinal peptide (VIP) gene enhances susceptibility to death from metastatic bladder cancer, two strains of mice were injected with MB49 murine bladder cancer cells. The growth and spread of the cancer...

Reproductiveaxis gene regulation during photostimulation and photorefractoriness in Yangzhou goose ganders.

Frontiers in zoology

Zhu H, Chen Z, Shao X, Yu J, Wei C, Dai Z, Shi Z.
PMID: 28250798
Front Zool. 2017 Feb 23;14:11. doi: 10.1186/s12983-017-0200-6. eCollection 2017.

BACKGROUND: The Yangzhou goose is a long-day breeding bird that has been increasingly produced in China. Artificial lighting programs are used for controlling its reproductive activities. This study investigated the regulations of photostimulation and photorefractoriness that govern the onset...

The Network Mechanism of the Central Circadian Pacemaker of the SCN: Do AVP Neurons Play a More Critical Role Than Expected?.

Frontiers in neuroscience

Mieda M.
PMID: 30858797
Front Neurosci. 2019 Feb 25;13:139. doi: 10.3389/fnins.2019.00139. eCollection 2019.

The suprachiasmatic nucleus (SCN) functions as the central circadian pacemaker in mammals and entrains to the environmental light/dark cycle. It is composed of multiple types of GABAergic neurons, and interneuronal communications among these neurons are essential for the circadian...

Octreotide reverses shock due to vasoactive intestinal peptide-secreting adrenal pheochromocytoma: A case report and review of literature.

World journal of clinical cases

Hu X, Cao W, Zhao M.
PMID: 30510956
World J Clin Cases. 2018 Nov 26;6(14):862-868. doi: 10.12998/wjcc.v6.i14.862.

Vasoactive intestinal peptide-producing tumors (VIPoma) usually originate in the pancreas and are characterized by diarrhea, hypokalemia, and achlorhydria (WDHA syndrome). In adults, nonpancreatic VIPoma is very rare. Herein, we report an unusual case of VIP-producing pheochromocytoma marked by persistent...

Conceptualization of a Parasympathetic Endocrine System.

Frontiers in neuroscience

Gorky J, Schwaber J.
PMID: 31607849
Front Neurosci. 2019 Sep 23;13:1008. doi: 10.3389/fnins.2019.01008. eCollection 2019.

We here propose a parasympathetic endocrine system (PES) comprised of circulating peptides released from secretory cells in the gut, significantly modulated by vagal projections from the dorsal motor nucleus of the vagus (DMV). While most of these gut peptides...

Neuropeptide G Protein-Coupled Receptors as Oncotargets.

Frontiers in endocrinology

Moody TW, Ramos-Alvarez I, Jensen RT.
PMID: 30008698
Front Endocrinol (Lausanne). 2018 Jun 29;9:345. doi: 10.3389/fendo.2018.00345. eCollection 2018.

Neuropeptide G protein-coupled receptors (GPCRs) are overexpressed on numerous cancer cells. In a number of tumors, such as small cell lung cancer (SCLC), bombesin (BB) like peptides and neurotensin (NTS) function as autocrine growth factors whereby they are secreted...

New insight in migraine pathogenesis: Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) in the circulation after sumatriptan.

Scandinavian journal of pain

Gazerani P, Cairns BE.
PMID: 29913624
Scand J Pain. 2013 Oct 01;4(4):208-210. doi: 10.1016/j.sjpain.2013.07.001.

No abstract available.

Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) in the circulation after sumatriptan.

Scandinavian journal of pain

Hansen JM, Fahrenkrug J, Petersen J, Wienecke T, Olsen KS, Ashina M.
PMID: 29913626
Scand J Pain. 2013 Oct 01;4(4):211-216. doi: 10.1016/j.sjpain.2013.04.002.

Background and purpose The origin of migraine pain is still elusive, but increasingly researchers focus on the neuropeptides in the perivascular space of cranial vessels as important mediators of nociceptive input during migraine attacks. The parasympathetic neurotransmitters, pituitary adenylate...

Drug Repositioning For Allosteric Modulation of VIP and PACAP Receptors.

Frontiers in endocrinology

Langer I, Latek D.
PMID: 34867774
Front Endocrinol (Lausanne). 2021 Nov 18;12:711906. doi: 10.3389/fendo.2021.711906. eCollection 2021.

Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are two neuropeptides that contribute to the regulation of intestinal motility and secretion, exocrine and endocrine secretions, and homeostasis of the immune system. Their biological effects are mediated by...

Showing 25 to 36 of 339 entries