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Showing 13 to 24 of 88 entries
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Low body mass index as a barrier to lung transplant in cystic fibrosis.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

Jennerich AL, Pryor JB, Wai TYH, Kapnadak SG, Aitken ML, Goss CH, Ramos KJ.
PMID: 34922852
J Cyst Fibros. 2021 Dec 15; doi: 10.1016/j.jcf.2021.12.001. Epub 2021 Dec 15.

RATIONALE: Low body mass index (BMI) may influence lung transplant decisions for patients with advanced cystic fibrosis (CF) lung disease.OBJECTIVE: Determine whether patients with advanced CF lung disease and BMI ≤17 kg/mMETHODS: Using merged United Network for Organ Sharing...

Increase in Prevalence of Diabetic Ketoacidosis at Diagnosis Among Youth With Type 1 Diabetes: The SEARCH for Diabetes in Youth Study.

Diabetes care

Jensen ET, Stafford JM, Saydah S, D'Agostino RB, Dolan LM, Lawrence JM, Marcovina S, Mayer-Davis EJ, Pihoker C, Rewers A, Dabelea D.
PMID: 34099516
Diabetes Care. 2021 Jul;44(7):1573-1578. doi: 10.2337/dc20-0389. Epub 2021 Jun 07.

OBJECTIVE: We previously reported a high (˜30%) but stable prevalence of diabetic ketoacidosis (DKA) at youth-onset diagnosis of type 1 diabetes (2002 and 2010). Given the changing demographics of youth-onset type 1 diabetes, we sought to evaluate temporal trends...

Racial and socioeconomic disparities in the efficacy of a family-based treatment programme for paediatric obesity.

Pediatric obesity

Davison GM, Fowler LA, Ramel M, Stein RI, Conlon RPK, Saelens BE, Welch RR, Perri MG, Epstein LH, Wilfley DE.
PMID: 33847074
Pediatr Obes. 2021 Oct;16(10):e12792. doi: 10.1111/ijpo.12792. Epub 2021 Apr 12.

BACKGROUND: Family-based behavioural weight loss treatment (FBT) is an evidence-based intervention for paediatric overweight/obesity (OV/OB), but little research has examined the relative efficacy of FBT across socioeconomic status (SES), and racial groups.METHOD: A total of 172 youth (7-11 years;...

Survival and Lung Transplant Outcomes for Individuals With Advanced Cystic Fibrosis Lung Disease Living in the United States and Canada: An Analysis of National Registries.

Chest

Ramos KJ, Sykes J, Stanojevic S, Ma X, Ostrenga JS, Fink A, Quon BS, Marshall BC, Faro A, Petren K, Elbert A, Goss CH, Stephenson AL.
PMID: 33878343
Chest. 2021 Sep;160(3):843-853. doi: 10.1016/j.chest.2021.04.010. Epub 2021 Apr 17.

BACKGROUND: Understanding how health outcomes differ for patients with advanced cystic fibrosis (CF) lung disease living in the United States compared with Canada has health policy implications.RESEARCH QUESTION: What are rates of lung transplant (LTx) and rates of death...

Precore and Basal Core Promoter Hepatitis B Virus (HBV) Variants Are Present From a Young Age and Differ Across HBV Genotypes.

Hepatology (Baltimore, Md.)

Lau DTY, Ganova-Raeva L, Wang J, Mogul D, Chung RT, Lisker-Melman M, Chang KM, Shaikh OS, Janssen HLA, Wahed AS, Lok AS.
PMID: 32860463
Hepatology. 2021 May;73(5):1637-1651. doi: 10.1002/hep.31506.

BACKGROUND AND AIMS: Hepatitis B virus (HBV) precore (PC) and dual basal core promoter (BCP) mutations halt and down-regulate hepatitis B e antigen (HBeAg) production respectively. PC mutation is rarely associated with HBV genotype A. We sought to examine...

rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis.

Journal of hepatology

Teo K, Abeysekera KWM, Adams L, Aigner E, Anstee QM, Banales JM, Banerjee R, Basu P, Berg T, Bhatnagar P, Buch S, Canbay A, Caprio S, Chatterjee A, Ida Chen YD, Chowdhury A, Daly AK, Datz C, de Gracia Hahn D, DiStefano JK, Dong J, Duret A, Emdin C, Fairey M, Gerhard GS, Guo X, Hampe J, Hickman M, Heintz L, Hudert C, Hunter H, Kelly M, Kozlitina J, Krawczyk M, Lammert F, Langenberg C, Lavine J, Li L, Lim HK, Loomba R, Luukkonen PK, Melton PE, Mori TA, Palmer ND, Parisinos CA, Pillai SG, Qayyum F, Reichert MC, Romeo S, Rotter JI, Im YR, Santoro N, Schafmayer C, Speliotes EK, Stender S, Stickel F, Still CD, Strnad P, Taylor KD, Tybjærg-Hansen A, Umano GR, Utukuri M, Valenti L, Wagenknecht LE, Wareham NJ, Watanabe RM, Wattacheril J, Yaghootkar H, Yki-Järvinen H, Young KA, Mann JP.
PMID: 32882372
J Hepatol. 2021 Jan;74(1):20-30. doi: 10.1016/j.jhep.2020.08.027. Epub 2020 Aug 31.

BACKGROUND & AIMS: A common genetic variant near MBOAT7 (rs641738C>T) has been previously associated with hepatic fat and advanced histology in NAFLD; however, these findings have not been consistently replicated in the literature. We aimed to establish whether rs641738C>T...

Lung function in children with cystic fibrosis in the USA and UK: a comparative longitudinal analysis of national registry data.

Thorax

Schlüter DK, Ostrenga JS, Carr SB, Fink AK, Faro A, Szczesniak RD, Keogh RH, Charman SC, Marshall BC, Goss CH, Taylor-Robinson D.
PMID: 33975926
Thorax. 2022 Feb;77(2):136-142. doi: 10.1136/thoraxjnl-2021-216849. Epub 2021 May 11.

RATIONALE: A previous analysis found significantly higher lung function in the US paediatric cystic fibrosis (CF) population compared with the UK with this difference apparently decreasing in adolescence and adulthood. However, the cross-sectional nature of the study makes it...

Interferon Gamma Release Assay and Tuberculin Skin Test Performance in Pregnant Women Living With and Without HIV.

Journal of acquired immune deficiency syndromes (1999)

Kaplan SR, Escudero JN, Mecha J, Richardson BA, Maleche-Obimbo E, Matemo D, Kinuthia J, John-Stewart GC, LaCourse SM.
PMID: 34629414
J Acquir Immune Defic Syndr. 2022 Jan 01;89(1):98-107. doi: 10.1097/QAI.0000000000002827.

BACKGROUND: HIV and pregnancy may affect latent TB infection (LTBI) diagnostics. Tuberculin skin test (TST) and newer generation QuantiFERON-TB Gold Plus (QFT-Plus) evaluations in pregnant women living with HIV (WLHIV) and without HIV are lacking.METHODS: In this cross-sectional study,...

Applying a Participatory Design Approach to Define Objectives and Properties of a "Data Profiling" Tool for Electronic Health Data.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Estiri H, Lovins T, Afzalan N, Stephens KA.
PMID: 27570651
AMIA Jt Summits Transl Sci Proc. 2016 Jul 20;2016:60-7. eCollection 2016.

We applied a participatory design approach to define the objectives, characteristics, and features of a "data profiling" tool for primary care Electronic Health Data (EHD). Through three participatory design workshops, we collected input from potential tool users who had...

Racial and socioeconomic disparities in the efficacy of a family-based treatment programme for paediatric obesity.

Pediatric obesity

Davison GM, Fowler LA, Ramel M, Stein RI, Conlon RPK, Saelens BE, Welch RR, Perri MG, Epstein LH, Wilfley DE.
PMID: 33847074
Pediatr Obes. 2021 Oct;16(10):e12792. doi: 10.1111/ijpo.12792. Epub 2021 Apr 12.

BACKGROUND: Family-based behavioural weight loss treatment (FBT) is an evidence-based intervention for paediatric overweight/obesity (OV/OB), but little research has examined the relative efficacy of FBT across socioeconomic status (SES), and racial groups.METHOD: A total of 172 youth (7-11 years;...

Empiric Antibiotic Use and Susceptibility in Infants With Bacterial Infections: A Multicenter Retrospective Cohort Study.

Hospital pediatrics

Feldman EA, McCulloh RJ, Myers AL, Aronson PL, Neuman MI, Bradford MC, Alpern ER, Balamuth F, Blackstone MM, Browning WL, Hayes K, Korman R, Leazer RC, Nigrovic LE, Marble R, Roben E, Williams DJ, Tieder JS.
PMID: 28729240
Hosp Pediatr. 2017 Jul 20; doi: 10.1542/hpeds.2016-0162. Epub 2017 Jul 20.

OBJECTIVES: To assess hospital differences in empirical antibiotic use, bacterial epidemiology, and antimicrobial susceptibility for common antibiotic regimens among young infants with urinary tract infection (UTI), bacteremia, or bacterial meningitis.METHODS: We reviewed medical records from infants

Longitudinal association between eating frequency and hemoglobin A1c and serum lipids in diabetes in the SEARCH for Diabetes in Youth study.

Pediatric diabetes

Li C, D'Agostino RB, Dabelea D, Liese AD, Mayer-Davis EJ, Pate R, Merchant AT.
PMID: 29708292
Pediatr Diabetes. 2018 Apr 30; doi: 10.1111/pedi.12690. Epub 2018 Apr 30.

BACKGROUND: Few studies have evaluated the prospective association of eating frequency with HbA1c levels and cardiovascular disease risk markers among youth with diabetes.OBJECTIVE: To examine the 5-year longitudinal association of eating frequency with HbA1c and serum lipid levels among...

Showing 13 to 24 of 88 entries