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Showing 133 to 139 of 139 entries
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Retention Esophagitis as a Significant Clinical Predictor of Progression to Esophageal Cancer in Achalasia.

Clinical endoscopy

Kim H, Park H, Choi H, Shin Y, Park H, Youn YH, Kim JH.
PMID: 29506341
Clin Endosc. 2018 Mar;51(2):161-166. doi: 10.5946/ce.2017.087. Epub 2018 Mar 06.

BACKGROUND/AIMS: Chronic liquid and/or food stasis caused by retention esophagitis (RE) in achalasia is a notable endoscopic finding because of the presence of a thickened or whitish esophageal mucosa and histologically altered squamous hyperplasia. We aimed to identify the...

The evolution of medulloblastoma therapy to personalized medicine.

F1000Research

Sengupta S, Pomeranz Krummel D, Pomeroy S.
PMID: 28713553
F1000Res. 2017 Apr 13;6:490. doi: 10.12688/f1000research.10859.1. eCollection 2017.

Recent advances in cancer genomics have revolutionized the characterization and classification of medulloblastomas. According to the current WHO guidelines, medulloblastomas are now classified into the following molecularly defined groups: Wnt signaling pathway (WNT)-activated, sonic hedgehog signaling pathway (SHH)-activated and...

Semisynthetic 'designer' p53 sheds light on a phosphorylation-acetylation relay.

Chemical science

Margiola S, Gerecht K, Müller MM.
PMID: 34221338
Chem Sci. 2021 May 19;12(24):8563-8570. doi: 10.1039/d1sc00396h.

The tumor suppressor protein p53 is a master regulator of cell fate. The activity of p53 is controlled by a plethora of posttranslational modifications (PTMs). However, despite extensive research, the mechanisms of this regulation are still poorly understood due...

Amperometric detection of tumor suppressor protein p53 via pencil graphite electrode for fast cancer diagnosis.

Analytical biochemistry

Deepa, Nohwal B, Chaudhary R, Pundir CS.
PMID: 34919898
Anal Biochem. 2021 Dec 14;114528. doi: 10.1016/j.ab.2021.114528. Epub 2021 Dec 14.

Cancer occupies the second place in terms of worldwide mortality. Early and fast diagnosis of cancer helps clinicians to expand therapeutic approaches ultimately leading towards early diagnosis of cancer patients. In the present work, we delineated an amperometric immunosensor...

Amperometric detection of tumor suppressor protein p53 via pencil graphite electrode for fast cancer diagnosis.

Analytical biochemistry

Deepa, Nohwal B, Chaudhary R, Pundir CS.
PMID: 34919898
Anal Biochem. 2021 Dec 15;639:114528. doi: 10.1016/j.ab.2021.114528. Epub 2021 Dec 15.

Cancer occupies the second place in terms of worldwide mortality. Early and fast diagnosis of cancer helps clinicians to expand therapeutic approaches ultimately leading towards early diagnosis of cancer patients. In the present work, we delineated an amperometric immunosensor...

Expression of p53 and p16 in Carcinoma Breast Tissue: Depicts Prognostic Significance or Coincidence.

Cureus

Rana MK, Rana APS, Khera U.
PMID: 34925997
Cureus. 2021 Nov 09;13(11):e19395. doi: 10.7759/cureus.19395. eCollection 2021 Nov.

Breast cancer remains the most common malignancy among the Indian female population. The p16 and p53 genes are frequently mutated in breast cancer. Therefore, we aimed to evaluate the prognostic significance of p16 and p53 overexpression in breast cancer...

Amperometric detection of tumor suppressor protein p53 via pencil graphite electrode for fast cancer diagnosis.

Analytical biochemistry

Deepa, Nohwal B, Chaudhary R, Pundir CS.
PMID: 34919898
Anal Biochem. 2021 Dec 15;639:114528. doi: 10.1016/j.ab.2021.114528. Epub 2021 Dec 15.

Cancer occupies the second place in terms of worldwide mortality. Early and fast diagnosis of cancer helps clinicians to expand therapeutic approaches ultimately leading towards early diagnosis of cancer patients. In the present work, we delineated an amperometric immunosensor...

Showing 133 to 139 of 139 entries