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Showing 13 to 24 of 148 entries
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Myofibroblasts and transforming growth factor-beta1 in reactive gingival overgrowths.

Journal of oral & maxillofacial research

Epivatianos A, Andreadis D, Iordanidis S.
PMID: 24422026
J Oral Maxillofac Res. 2013 Apr 01;4(1):e3. doi: 10.5037/jomr.2013.4103.

OBJECTIVES: The purpose of this study was to evaluate the oral health-related quality of life of patients treated with implant-supported mandibular overdentures and to compare the attachment systems used.MATERIAL AND METHODS: The presence of myofibroblasts as well as transforming...

Increased expression of the homologue of enhancer-of-split 1 protects neurons from beta amyloid neurotoxicity and hints at an alternative role for transforming growth factor beta1 as a neuroprotector.

Alzheimer's research & therapy

Chacón PJ, Rodríguez-Tébar A.
PMID: 22849569
Alzheimers Res Ther. 2012 Jul 31;4(4):31. doi: 10.1186/alzrt134.

INTRODUCTION: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition of β-amyloid (Aβ) in the brain, which produces progressive neuronal loss and dementia. We recently demonstrated that the noxious effects of Aβ on cultured hippocampal neurons are...

Hypoxia-Inducible Factor 1α Regulates the Transforming Growth Factor β1/SMAD Family Member 3 Pathway to Promote Breast Cancer Progression.

Journal of breast cancer

Peng J, Wang X, Ran L, Song J, Luo R, Wang Y.
PMID: 30275854
J Breast Cancer. 2018 Sep;21(3):259-266. doi: 10.4048/jbc.2018.21.e42. Epub 2018 Sep 20.

PURPOSE: The transforming growth factor β1 (TGF-β1)/SMAD family member 3 (SMAD3) pathway, and hypoxia-inducible factor 1α (HIF-1α) are two key players in various types of malignancies including breast cancer. The TGF-β1/SMAD3 pathway can interact with HIF-1α in some diseases;...

Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes.

Cancer management and research

Maalouf K, Baydoun E, Rizk S.
PMID: 21448298
Cancer Manag Res. 2011 Feb 14;3:39-47. doi: 10.2147/CMR.S15109.

BACKGROUND: Adult lymphoblastic leukemia (ALL) is a malignancy that occurs in white blood cells. The overall cure rate in children is 85%, whereas it is only 40% in adults. Kefir is an important probiotic that contains many bioactive ingredients,...

Effects of sevoflurane on wound healing process.

Korean journal of anesthesiology

Cha MS, Lee HJ, Bae JH, Yang WS, Baik SW.
PMID: 30625834
Korean J Anesthesiol. 2009 Jul;57(1):78-83. doi: 10.4097/kjae.2009.57.1.78.

BACKGROUND: Wound healing process is a tissue response to trauma which leads to tissue repair through complex biological stages. Sevoflurane is a widely used inhalation anesthetic for surgery, but there has been no study about its effect on wound...

Regulation of transforming growth factor-beta1 by circANKS1B/miR-515-5p affects the metastatic potential and cisplatin resistance in oral squamous cell carcinoma.

Bioengineered

Yan J, Xu H.
PMID: 34781814
Bioengineered. 2021 Dec;12(2):12420-12430. doi: 10.1080/21655979.2021.2005221.

Oral squamous cell carcinoma (OSCC) is the most common oral cancer, with an increasing worldwide incidence and a worsening prognosis. Emerging evidence confirms that circular RNAs (circRNAs) play a critical role in tumor progression via sponging miRNAs. A previous...

Transglutaminase 2 mediates lung inflammation and remodeling by transforming growth factor beta 1 .

Experimental lung research

Kim YC, Kim J, Kim S, Bae B, Kim RL, Jeong EM, Cho SH, Kang HR.
PMID: 34818962
Exp Lung Res. 2021 Dec;47(10):465-475. doi: 10.1080/01902148.2021.1998733. Epub 2021 Nov 24.

Transforming growth factor beta 1 (TGF-β1) induces pulmonary fibrosis by enhancing epithelial apoptosis and affects the enzymatic activity of transglutaminase 2 (TG2). The aim of this study was to determine the role of TG2 in TGF-β1-induced lung remodeling and...

Anti-fibrotic Actions of Equine Interleukin-10 on Transforming Growth Factor-Beta1-Stimulated Dermal Fibroblasts Isolated From Limbs of Horses.

Frontiers in veterinary science

Wise LM, Stuart GS, Sriutaisuk K, Adams BR, Riley CB, Theoret CL.
PMID: 33195583
Front Vet Sci. 2020 Sep 18;7:577835. doi: 10.3389/fvets.2020.577835. eCollection 2020.

Fibroproliferative disorders occur in both humans and horses following skin injury. In horses, wound healing on the limb is often complicated by the formation of fibroproliferative exuberant granulation tissue, characterized by persistent expression of pro-fibrotic transforming growth factor-beta1 (TGF-β1)...

Transforming growth factor-beta1 promotes Geistlich Bio-Oss.

International journal of clinical and experimental pathology

Li C, Bi W, Zhang D, Sang Z, Li L, Yu Y.
PMID: 31966803
Int J Clin Exp Pathol. 2017 Sep 01;10(9):9310-9317. eCollection 2017.

Inhibiting inflammation is helpful in relieving the absorption of alveolar bone and promoting periodontal bone regeneration. In a previous study, we showed that transforming growth factor-beta1 (TGF-β1)-induced Treg cells inhibit the absorption of tissue-engineered cartilage caused by endogenous IFN-γ...

Effect of Sini decoction on angiotensin Ⅱ transforming growth factor β1 and connective tissue growth factor in rats with myocardial fibrosis-induced banding of the abdominal aorta.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

Shi Y, Liu C, Zhai J.
PMID: 32185976
J Tradit Chin Med. 2018 Jun;38(3):427-432.

OBJECTIVE: To investigate the effect of Sini decoction on rats with myocardial fibrosis induced by banding the abdominal aorta, and explore the mechanism underlying its actions on angiotensin ¢ò(Ang ¢ò), transforming growth factor-¦Â1 (TGF-¦Â1) and connective tissue growth factor...

Effect of octreotide on pancreatic fibrosis in rats with high-fat diet-induced obesity.

International journal of clinical and experimental pathology

Ye T, Chen YH, Gao JH, Wang XX, Qiang O, Tang CW, Liu R.
PMID: 31949553
Int J Clin Exp Pathol. 2018 Oct 01;11(10):4784-4794. eCollection 2018.

BACKGROUND/AIMS: To explore the effect of octreotide on pancreatic fibrosis induced by high-fat diet (HFD) and its mechanism of action.METHODS: Sprague-Dawley (SD) rats were assigned to control, HFD, or octreotide treatment groups. Glucose and insulin tolerance tests (GTT and...

Psychosocial Stress and Age Influence Depression and Anxiety-Related Behavior, Drive Tumor Inflammatory Cytokines and Accelerate Prostate Cancer Growth in Mice.

Frontiers in oncology

Bellinger DL, Dulcich MS, Molinaro C, Gifford P, Lorton D, Gridley DS, Hartman RE.
PMID: 34604038
Front Oncol. 2021 Sep 16;11:703848. doi: 10.3389/fonc.2021.703848. eCollection 2021.

Prostate cancer (PCa) prevalence is higher in older men and poorer coping with psychosocial stressors effect prognosis. Yet, interactions between age, stress and PCa progression are underexplored. Therefore, we characterized the effects of age and isolation combined with restraint...

Showing 13 to 24 of 148 entries