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Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Gendy AM, Elnagar MR, Allam MM, Mousa MR, Khodir AE, El-Haddad AE, Elnahas OS, Fayez SM, El-Mancy SS.
PMID: 34489150
Biomed Pharmacother. 2022 Jan;145:112122. doi: 10.1016/j.biopha.2021.112122. Epub 2021 Sep 04.

OBJECTIVE: Berberine (BBR) is a known alkaloid that has verified its protective effects against ischemia/reperfusion (I/RN) lesion in multiple organs but its poor oral bioavailability limited its use. Despite the previous works, its possible impact on the warm hepatic...

Fecal Calprotectin Is Increased in Stroke.

Journal of clinical medicine

Park SY, Lee SP, Kim WJ.
PMID: 35011900
J Clin Med. 2021 Dec 29;11(1). doi: 10.3390/jcm11010159.

BACKGROUND: While there have been major advances in unveiling the mechanisms comprising the ischemic cascade of CNS, stroke continues to be a significant burden. There is a need to extend the focus toward peripheral changes, and the brain-gut axis...

Showing 949 to 950 of 950 entries