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Showing 13 to 23 of 23 entries
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Role of ADP and thromboxanes in human thrombus formation in ex vivo models.

Platelets

Sakariassen KS, Orning L, Stormorken H.
PMID: 16793672
Platelets. 1997;8(6):385-90. doi: 10.1080/09537109777069.

Adenosine diphosphate (ADP) and prostaglandin derivatives play important roles in thrombogenesis. Their roles in platelet function have been extensively studied for more than three and two decades, respectively. Of further importance for thrombogenesis, and perhaps for atherogenesis as well,...

Inhibition of NO-synthase and degranulation of rat omental mast cells in vitro.

Mediators of inflammation

Northover AM, Northover BJ.
PMID: 18475736
Mediators Inflamm. 1996;5(4):257-61. doi: 10.1155/S0962935196000361.

Mast cell amines, platelet-activating factor (PAF), thromboxanes and leukotrienes have been shown to be released during nitric oxide-synthase inhibition in the rat intestine. Mast cells in rat isolated omentum (OMCs) or isolated from the rat peritoneal cavity (PMCs) have...

Vasoactivity of prostanoids in the trout (Oncorhynchus mykiss) coronary system: modification by noradrenaline.

Fish physiology and biochemistry

Mustafa T, Agnisola C.
PMID: 24198195
Fish Physiol Biochem. 1994 Jul;13(3):249-61. doi: 10.1007/BF00004363.

An isolated non-working trout heart, cannulated through the coronary artery and perfused with oxygenated saline with a coronary pressure head of 3.0 kPa has been used in this study. Effects on the coronar resistance of catecholamines, thromboxanes (TXs) and...

Effects of Arachidonic Acid Metabolites on Cardiovascular Health and Disease.

International journal of molecular sciences

Zhou Y, Khan H, Xiao J, Cheang WS.
PMID: 34769460
Int J Mol Sci. 2021 Nov 06;22(21). doi: 10.3390/ijms222112029.

Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell membranes and metabolized by cyclooxygenase (COX), cytochrome P450 (CYP) enzymes, and lipid oxygenase (LOX) pathways to regulate complex cardiovascular function under physiological and pathological...

Dietary Fish, Fish Nutrients, and Immune Function: A Review.

Frontiers in nutrition

Mendivil CO.
PMID: 33553231
Front Nutr. 2021 Jan 20;7:617652. doi: 10.3389/fnut.2020.617652. eCollection 2020.

Dietary habits have a major impact on the development and function of the immune system. This impact is mediated both by the intrinsic nutritional and biochemical qualities of the diet, and by its influence on the intestinal microbiota. Fish...

Expression of cyclooxygenase 2 and cytosolic phospholipase A(2) in the liver tissue of patients with chronic hepatitis and liver cirrhosis.

Hepatology research : the official journal of the Japan Society of Hepatology

Cheng J, Imanishi H, Iijima H, Shimomura S, Yamamoto T, Amuro Y, Kubota A, Hada T.
PMID: 12076714
Hepatol Res. 2002 Jul;23(3):185-195. doi: 10.1016/s1386-6346(01)00177-2.

Cyclooxgenase (COX) and phospholipase A(2) (PLA(2)) are crucial rate-limiting enzymes involved in the conversion of arachidonic acid to prostaglandin H(2), the precursor of various compounds including prostaglandins (PGs), prostacyclin, and thromboxanes in the process of PGs' synthesis. Recent studies...

Stable isotope dilution gas chromatography/mass spectrometry of prostaglandins and leukotrienes.

Biological trace element research

Blair IA.
PMID: 24254608
Biol Trace Elem Res. 1987 Apr;12(1):259-60. doi: 10.1007/BF02796685.

The group of arachidonic acid metabolites comprising the prostaglandins, thromboxanes, and leukotrienes (eicosanoids) are extremely potent, biologically active compounds. Their properties include proaggregatory anti-aggregatory activity for platelets, chemotactic activity for neutrophils, vasoactive activity, and contractile activity to smooth muscle....

Platelets and cardiac arrhythmia.

Frontiers in physiology

de Jong JS, Dekker LR.
PMID: 21423401
Front Physiol. 2010 Dec 30;1:166. doi: 10.3389/fphys.2010.00166. eCollection 2010.

Sudden cardiac death (SCD) remains one of the most prevalent modes of death in industrialized countries, and myocardial ischemia due to thrombotic coronary occlusion is its primary cause. The role of platelets in the occurrence of SCD extends beyond...

Fast atom bombardment and collision-induced dissociation of prostaglandins and thromboxanes: Some examples of charge remote fragmentation.

Journal of the American Society for Mass Spectrometry

Zirrolli JA, Davoli E, Bettazzoli L, Gross M, Murphy RC.
PMID: 24248827
J Am Soc Mass Spectrom. 1990 Jul;1(4):325-35. doi: 10.1016/1044-0305(90)85009-B.

The mass spectra of products found by collisional activation of selected prostaglandins and thromboxanes were studied by tandem mass spectrometry as barium carboxylate salts and as carboxylate anions. Collision-induced dissociation (CID) of these closed shell ions generated by fast...

Quality assessment of unsaturated iron-binding protein capacity in Iraqi patients undergoing hemodialysis.

Journal of pharmacy & bioallied sciences

Raoof IB, Abdalah ME.
PMID: 33100783
J Pharm Bioallied Sci. 2020 Jul-Sep;12(3):246-251. doi: 10.4103/jpbs.JPBS_12_20. Epub 2020 Jul 18.

Hemodialysis is autoimmune disease result from inflammation, oxidative stress, and fibrosis. It is characterized by renal glomeruli damage, podocyte injury, tubule interstitial, and proteinuria. Electrolyte balance is the main function of the renal and any form of electrolyte disorders...

Eicosanoids in Cancer: New Roles in Immunoregulation.

Frontiers in pharmacology

Johnson AM, Kleczko EK, Nemenoff RA.
PMID: 33364964
Front Pharmacol. 2020 Nov 18;11:595498. doi: 10.3389/fphar.2020.595498. eCollection 2020.

Eicosanoids represent a family of active biolipids derived from arachidonic acid primarily through the action of cytosolic phospholipase A2-α. Three major downstream pathways have been defined: the cyclooxygenase (COX) pathway which produces prostaglandins and thromboxanes; the 5-lipoxygenase pathway (5-LO),...

Showing 13 to 23 of 23 entries