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Showing 25 to 36 of 72 entries
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Switching the Switch: Ligand Induced Disulfide Formation in HDAC8.

Chemistry (Weinheim an der Bergstrasse, Germany)

Jänsch N, Sugiarto WO, Muth M, Kopranovic A, Desczyk C, Ballweg M, Kirschhöfer F, Brenner-Weiss G, Meyer-Almes FJ.
PMID: 32428298
Chemistry. 2020 Oct 15;26(58):13249-13255. doi: 10.1002/chem.202001712. Epub 2020 Sep 11.

Human histone deacetylase 8 is a well-recognized target for T-cell lymphoma and particularly childhood neuroblastoma. PD-404,182 was shown to be a selective covalent inhibitor of HDAC8 that forms mixed disulfides with several cysteine residues and is also able to...

Synthesis of (benzenesulfonyl)difluoromethyl thioethers from ((difluoromethyl)sulfonyl)benzene and organothiocyanates generated .

Organic & biomolecular chemistry

Wu C, Shen X, Dai J, Xu J, Xu H.
PMID: 34524317
Org Biomol Chem. 2021 Sep 15;19(35):7607-7610. doi: 10.1039/d1ob01215k.

Easily available aryl and alkyl thiocyanates were converted into the corresponding (benzenesulfonyl)difluoromethyl thioethers

Phenol-containing macrocyclic diamides as new catalysts in the highly regioselective conversion of epoxides to beta-hydroxy thiocyanates.

The Journal of organic chemistry

Sharghi H, Nasseri MA, Niknam K.
PMID: 11681940
J Org Chem. 2001 Nov 02;66(22):7287-93. doi: 10.1021/jo0103266.

The regioselective ring-opening reactions of some epoxides with ammonium thiocyanate in the presence of a series of new phenol-containing macrocyclic diamides and also dibenzo-18-crown-6-, 18-crown-6-, benzo-15-crown-5-, and pyridine-containing macrocyclic diamide have been studied. The epoxides were subject to cleavage...

Reduction of Aryl Thiocyanates with SmI(2) and Pd-Catalyzed Coupling with Aryl Halides as a Route to Mixed Aryl Sulfides.

The Journal of organic chemistry

Still IW, Toste FD.
PMID: 11667721
J Org Chem. 1996 Nov 01;61(22):7677-7680. doi: 10.1021/jo961029h.

A series of aryl iodides, with a range of substituents, has been successfully coupled using 10 mol % Pd catalyst with samarium thiolates, derived from the corresponding aryl thiocyanates upon reductive cleavage with SmI(2). Reactions proceed in THF at...

Revisiting nucleophilic substitution reactions: microwave-assisted synthesis of azides, thiocyanates, and sulfones in an aqueous medium.

The Journal of organic chemistry

Ju Y, Kumar D, Varma RS.
PMID: 16901176
J Org Chem. 2006 Aug 18;71(17):6697-700. doi: 10.1021/jo061114h.

A practical, rapid, and efficient microwave (MW) promoted synthesis of various azides, thiocyanates, and sulfones is described in an aqueous medium. This general and expeditious MW-enhanced nucleophilic substitution approach uses easily accessible starting materials such as halides or tosylates...

Selective determination of cyanides by gas diffusion-stopped flow-sequential injection analysis and an on-line standard addition approach.

Analytica chimica acta

Themelis DG, Karastogianni SC, Tzanavaras PD.
PMID: 19100887
Anal Chim Acta. 2009 Jan 19;632(1):93-100. doi: 10.1016/j.aca.2008.10.074. Epub 2008 Nov 06.

A highly selective sequential injection (SI) method for the automated determination of weak-acid-dissociable cyanides is reported. The analytical procedure is based on the on-line reaction of the analyte with ninhydrin in carbonate medium to form a coloured product (lambda(max)=510...

Neutral complexes of first row transition metals bearing unbound thiocyanates and their assembly on metallic surfaces.

Journal of the American Chemical Society

Ciszek JW, Keane ZK, Cheng L, Stewart MP, Yu LH, Natelson D, Tour JM.
PMID: 16522098
J Am Chem Soc. 2006 Mar 15;128(10):3179-89. doi: 10.1021/ja055459d.

A series of transition metal coordination complexes designed to assemble on gold surfaces was synthesized, their electronic structure and transitions analyzed, and their magnetic properties studied. By taking advantage of recently developed thiocyanate assembly protocols, these molecules were then...

About a synthetic saliva for in vitro studies.

Talanta

Gal JY, Fovet Y, Adib-Yadzi M.
PMID: 18968202
Talanta. 2001 Mar 16;53(6):1103-15. doi: 10.1016/s0039-9140(00)00618-4.

Numerous artificial salivas have been used during studies in odontology. These salivas have compositions, which are more or less the same as that of natural saliva. In this article, we are presenting a discussion about the various media described...

Anion-exchange studies of metal thiocyanates in aqueous and mixed solvent systems.

Talanta

Singh D, Tandon SN.
PMID: 18962404
Talanta. 1979 Feb;26(2):163-5. doi: 10.1016/0039-9140(79)80240-4.

The anion-exchange behaviour of metal ions in aqueous NH(4)CNS and aqueous NH(4)CNS-organic solvent mixtures has been studied. The effect of the pH and the concentrations of thiocyanate and organic solvent on the distribution coefficients has been investigated. Fifteen binary...

Fluorescence spectroscopic studies of (acetamide + sodium/potassium thiocyanates) molten mixtures: composition and temperature dependence.

The journal of physical chemistry. B

Guchhait B, Gazi HA, Kashyap HK, Biswas R.
PMID: 20345185
J Phys Chem B. 2010 Apr 22;114(15):5066-81. doi: 10.1021/jp1001176.

Steady state and time-resolved fluorescence spectroscopic techniques have been used to explore the Stokes' shift dynamics and rotational relaxation of a dipolar solute probe in molten mixtures of acetamide (CH(3)CONH(2)) with sodium and potassium thiocyanates (Na /KSCN) at T...

Temperature-induced phase separation of nonionic polyoxyethylated surfactant and application to extraction of metal thiocyanates.

Analytical chemistry

Okada T.
PMID: 19518042
Anal Chem. 1992 Sep;64(18):2138-42. doi: 10.1021/ac00042a019.

No abstract available.

Dihalo(imidazolium)sulfuranes: A Versatile Platform for the Synthesis of New Electrophilic Group-Transfer Reagents.

Journal of the American Chemical Society

Talavera G, Peña J, Alcarazo M.
PMID: 26132748
J Am Chem Soc. 2015 Jul 15;137(27):8704-7. doi: 10.1021/jacs.5b05287. Epub 2015 Jul 01.

The syntheses of imidazolium thiocyanates and imidazolium thioalkynes from dihalo(imidazolium) sulfuranes are reported and their reactivities as CN(+) and R-CC(+) synthons evaluated, respectively. The easy and scalable preparation of these electrophilic reagents, their operationally simple handling, broad substrate scope,...

Showing 25 to 36 of 72 entries