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[EFFECT OF BLOOD MICROENVIRONMENT OF RATS WITH HEPATIC FIBROSIS ON DIFFERENTIATION OF HUMAN UMBILICAL CORD MESENCHYMAL STEM CELLS INTO HEPATOCYTES AND ITS MECHANISMS].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery

Yan C, Xue G, Zhang W, Han X, Liu J, Hou Y.
PMID: 29786272
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2016 Jun 08;30(6):754-760. doi: 10.7507/1002-1892.20160154.

OBJECTIVE: To investigate the effect of blood microenvironment of rats with hepatic fibrosis on differentiation of human umbilical cord mesenchymal stem cells (HUCMSCs) into hepatocytes and its mechanisms.METHODS: Eighteen male adult Sprague Dawley rats [weighing, (200±20) g] were used,...

Laser-induced construction of multi-branched CuS nanodendrites with excellent surface-enhanced Raman scattering spectroscopy in repeated applications.

Optics express

Li S, Zhang H, Xu L, Chen M.
PMID: 28789128
Opt Express. 2017 Jul 10;25(14):16204-16213. doi: 10.1364/OE.25.016204.

We report on the successful fabrication of multi-branched CuS nanodendrites with average branch length of about 20 nm by laser ablation of bulk Cu target in thioacetamide (TAA) solution. During the nucleation of Cu and S species, the accurate...

Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis.

Asian Pacific journal of tropical medicine

El-Lakkany NM, El-Maadawy WH, Seif El-Din SH, Hammam OA, Mohamed SH, Ezzat SM, Safar MM, Saleh S.
PMID: 28647181
Asian Pac J Trop Med. 2017 May;10(5):444-453. doi: 10.1016/j.apjtm.2017.05.012. Epub 2017 May 17.

OBJECTIVE: To investigate the antifibrotic role of rosmarinic acid (RA), a natural polyphenolic compound, on HSCs activation/proliferation and apoptosis in vitro and in vivo.METHODS: The impact of RA on stellate cell line (HSC-T6) proliferation, activation and apoptosis was assessed...

Metabolomic Assessment of Acute Cholestatic Injuries Induced by Thioacetamide and by Bile Duct Ligation, and the Protective Effects of Huang-Lian-Jie-Du-Decoction.

Frontiers in pharmacology

Wei DD, Wang JS, Duan JA, Kong LY.
PMID: 29867467
Front Pharmacol. 2018 May 08;9:458. doi: 10.3389/fphar.2018.00458. eCollection 2018.

Huang-Lian-Jie-Du-Decoction, a traditional Chinese formula, has been reported to protect liver from various injuries. Two cholestasis models of rats induced by thioacetamide and by bile duct ligation were established and treated with Huang-Lian-Jie-Du-Decoction. Nuclear Magnetic Resonance-based urinary metabolic profiles...

ZnS/ZnO@CNT and ZnS@CNT nanocomposites by gas phase conversion of ZnO@CNT. A systematic study of their photocatalytic properties.

Dalton transactions (Cambridge, England : 2003)

Okeil S, Krausmann J, Dönges I, Pfleger S, Engstler J, Schneider JJ.
PMID: 28374025
Dalton Trans. 2017 Apr 19;46(16):5189-5201. doi: 10.1039/c7dt00407a.

ZnS nanoparticles have been synthesized on vertically aligned carbon nanotubes by gas-phase conversion of ZnO nanoparticles which have been tethered on vertically aligned carbon nanotubes using atomic layer deposition (ALD). The resulting ZnO@CNT nanocomposite has been converted to ZnS@CNT...

Protective Effects of Co-Enzyme Q10 on Thioacetamide-Induced Acute Liver Damage and Its Correlation With Behavioral, Biochemical, and Pathological Factors.

Iranian Red Crescent medical journal

Ashkani-Esfahani S, Bagheri F, Emami Y, Esmaeilzadeh E, Azarpira N, Hassanabadi N, Keshtkar M, Farjam M, Koohi-Hosseinabadi O, Noorafshan A.
PMID: 28058114
Iran Red Crescent Med J. 2016 Jun 19;18(8):e29166. doi: 10.5812/ircmj.29166. eCollection 2016 Aug.

BACKGROUND: Acute liver damage may be followed by biochemical, behavioral, and pathological alterations, which can result in serious complications and even death.OBJECTIVES: In this experimental study we determined whether coenzyme Q10 (CoQ10), a common supplementary medicine known to have...

SPARC gene deletion protects against toxic liver injury and is associated to an enhanced proliferative capacity and reduced oxidative stress response.

Oncotarget

Peixoto E, Atorrasagasti C, Malvicini M, Fiore E, Rodriguez M, Garcia M, Finocchieto P, Poderoso JJ, Corrales F, Mazzolini G.
PMID: 31289615
Oncotarget. 2016 May 18;10(41):4169-4179. doi: 10.18632/oncotarget.9456. eCollection 2019 Jun 25.

SPARC, also known as osteonectin and BM-40, is a matricellular protein with a number of biological functions. Hepatic SPARC expression is induced in response to thioacetamide, bile-duct ligation, and acute injuries such as concanavalin A and lipopolysacharide (LPS)/D-galactosamine. We...

Selective removal of anionic dyes with exceptionally high adsorption capacity and removal of dichromate (Cr.

Journal of hazardous materials

Chowdhury A, Kumari S, Khan AA, Hussain S.
PMID: 31759757
J Hazard Mater. 2020 Mar 05;385:121602. doi: 10.1016/j.jhazmat.2019.121602. Epub 2019 Nov 06.

An adsorbent Ni-Co-S/CTAB nanocomposites have been synthesized at low temperature in aqueous medium using nickel acetate, cobalt acetate, thioacetamide and hexadecyltrimethyl ammonium bromide (CTAB) as reagents. The nanocomposites exhibited exceptionally high adsorption capacity towards anionic adsorbates with high selectivity....

Lipopolysaccharide/Toll-like receptor 4 signaling pathway involved Qingdu decoction treating severe liver injury merging with endotoxemia.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

Cao W, Du Y, Gao L, Che N, Zhang Q, Luo J, Cao W, Fu X, Wang R.
PMID: 31682380
J Tradit Chin Med. 2017 Jun;37(3):371-377.

OBJECTIVE: To investigate the protective effects and underlying mechanism of Qingdu decoction (QDD) on experimental rats with severe liver injury induced by thioacetamide (TAA).METHODS: A total of 40 Wistar rats were randomly divided into normal group (n = 10)...

Thioacetamide-induced norepinephrine production by hepatocytes is associated with hepatic stellate cell activation and liver fibrosis.

Current molecular pharmacology

Tang WC, Chang YW, Che M, Wang MH, Lai KK, Fueger PT, Huang W, Lin SB, Lai KKY.
PMID: 33845730
Curr Mol Pharmacol. 2021 Apr 12; doi: 10.2174/1874467214666210412144416. Epub 2021 Apr 12.

BACKGROUND: Collagen production by activated hepatic stellate cells (HSCs) to encapsulate injury is part of the natural wound-healing response in injured liver. However, persistent activation of HSCs can lead to pathological fibrogenesis. Such persistent HSC activation could be mediated...

Controlled synthesis of olive-shaped Bi2S3/BiVO4 microspheres through a limited chemical conversion route and enhanced visible-light-responding photocatalytic activity.

Dalton transactions (Cambridge, England : 2003)

Ma DK, Guan ML, Liu SS, Zhang YQ, Zhang CW, He YX, Huang SM.
PMID: 22415457
Dalton Trans. 2012 May 14;41(18):5581-6. doi: 10.1039/c2dt30099k. Epub 2012 Mar 14.

Well-defined olive-shaped Bi(2)S(3)/BiVO(4) microspheres were synthesized through a limited chemical conversion route (LCCR), where olive-shaped BiVO(4) microspheres and thioacetamide (TAA) were used as precursors and sulfur source, respectively. The as-synthesized products were characterized by X-ray diffraction (XRD), field emission...

Hepatoprotective effect of Saccharomyces Cervisciae Cell Wall Extract against thioacetamide-induced liver fibrosis in rats.

Heliyon

El-Gendy ZA, El-Marasy SA, Ahmed RF, El-Batran SA, Abd El-Rahman SS, Ramadan A, Youssef SAH.
PMID: 34159266
Heliyon. 2021 May 27;7(6):e07159. doi: 10.1016/j.heliyon.2021.e07159. eCollection 2021 Jun.

Fibrosis represents a common outcome of almost all chronic liver diseases and leads to an impairment of liver function that requires medical intervention. The current study aimed to evaluate the potential anti-fibrotic effect of

Showing 25 to 36 of 356 entries