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Understanding Traditional Chinese Medicine Therapeutics: An Overview of the Basics and Clinical Applications.

Healthcare (Basel, Switzerland)

Matos LC, Machado JP, Monteiro FJ, Greten HJ.
PMID: 33804485
Healthcare (Basel). 2021 Mar 01;9(3). doi: 10.3390/healthcare9030257.

Traditional Chinese medicine (TCM) is a systematic healthcare system developed from clinical experience based on a scientific model of regulation. TCM relies on unique theories and practices to treat diseases and enhance health. These practices include Chinese herbal medicine...

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Matos LC, Machado JP, Monteiro FJ, et al. Understanding Traditional Chinese Medicine Therapeutics: An Overview of the Basics and Clinical Applications. Healthcare (Basel). 2021;9(3)doi: 10.3390/healthcare9030257.
Matos, L. C., Machado, J. P., Monteiro, F. J., & Greten, H. J. (2021). Understanding Traditional Chinese Medicine Therapeutics: An Overview of the Basics and Clinical Applications. Healthcare (Basel, Switzerland), 9(3), . https://doi.org/10.3390/healthcare9030257
Matos, Luís Carlos, et al. "Understanding Traditional Chinese Medicine Therapeutics: An Overview of the Basics and Clinical Applications." Healthcare (Basel, Switzerland) vol. 9,3 (2021). doi: https://doi.org/10.3390/healthcare9030257
Matos LC, Machado JP, Monteiro FJ, Greten HJ. Understanding Traditional Chinese Medicine Therapeutics: An Overview of the Basics and Clinical Applications. Healthcare (Basel). 2021 Mar 01;9(3). doi: 10.3390/healthcare9030257. PMID: 33804485; PMCID: PMC8000828.
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A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection.

Obesity medicine

AbdelMassih AF, Ye J, Kamel A, Mishriky F, Ismail HA, Ragab HA, El Qadi L, Malak L, Abdu M, El-Husseiny M, Ashraf M, Hafez N, AlShehry N, El-Husseiny N, AbdelRaouf N, Shebl N, Hafez N, Youssef N, Afdal P, Hozaien R, Menshawey R, Saeed R, Fouda R.
PMID: 32835124
Obes Med. 2020 Sep;19:100281. doi: 10.1016/j.obmed.2020.100281. Epub 2020 Jul 15.

Furin, a cleavage enzyme, is increasingly recognized in the pathogenesis of metabolic syndrome. Its cleavage action is an essential activation step for the endothelial pathogenicity of several viruses including SARS-CoV-2. This Furin-mediated endothelial tropism seems to underlie the multi-organ...

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AbdelMassih AF, Ye J, Kamel A, et al. A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection. Obes Med. 2020;19:100281doi: 10.1016/j.obmed.2020.100281.
AbdelMassih, A. F., Ye, J., Kamel, A., Mishriky, F., Ismail, H. A., Ragab, H. A., El Qadi, L., Malak, L., Abdu, M., El-Husseiny, M., Ashraf, M., Hafez, N., AlShehry, N., El-Husseiny, N., AbdelRaouf, N., Shebl, N., Hafez, N., Youssef, N., Afdal, P., Hozaien, R., Menshawey, R., Saeed, R., & Fouda, R. (2020). A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection. Obesity medicine, 19100281. https://doi.org/10.1016/j.obmed.2020.100281
AbdelMassih, Antoine Fakhry, et al. "A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection." Obesity medicine vol. 19 (2020): 100281. doi: https://doi.org/10.1016/j.obmed.2020.100281
AbdelMassih AF, Ye J, Kamel A, Mishriky F, Ismail HA, Ragab HA, El Qadi L, Malak L, Abdu M, El-Husseiny M, Ashraf M, Hafez N, AlShehry N, El-Husseiny N, AbdelRaouf N, Shebl N, Hafez N, Youssef N, Afdal P, Hozaien R, Menshawey R, Saeed R, Fouda R. A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection. Obes Med. 2020 Sep;19:100281. doi: 10.1016/j.obmed.2020.100281. Epub 2020 Jul 15. PMID: 32835124; PMCID: PMC7362855.
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Advancing Personalized Medicine in Common Forms of Parkinson's Disease through Genetics: Current Therapeutics and the Future of Individualized Management.

Journal of personalized medicine

Reed X, Schumacher-Schuh A, Hu J, Bandres-Ciga S.
PMID: 33804504
J Pers Med. 2021 Mar 01;11(3). doi: 10.3390/jpm11030169.

Parkinson's disease (PD) is a condition with heterogeneous clinical manifestations that vary in age at onset, rate of progression, disease course, severity, motor and non-motor symptoms, and a variable response to antiparkinsonian drugs. It is considered that there are...

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Reed X, Schumacher-Schuh A, Hu J, et al. Advancing Personalized Medicine in Common Forms of Parkinson's Disease through Genetics: Current Therapeutics and the Future of Individualized Management. J Pers Med. 2021;11(3)doi: 10.3390/jpm11030169.
Reed, X., Schumacher-Schuh, A., Hu, J., & Bandres-Ciga, S. (2021). Advancing Personalized Medicine in Common Forms of Parkinson's Disease through Genetics: Current Therapeutics and the Future of Individualized Management. Journal of personalized medicine, 11(3), . https://doi.org/10.3390/jpm11030169
Reed, Xylena, et al. "Advancing Personalized Medicine in Common Forms of Parkinson's Disease through Genetics: Current Therapeutics and the Future of Individualized Management." Journal of personalized medicine vol. 11,3 (2021). doi: https://doi.org/10.3390/jpm11030169
Reed X, Schumacher-Schuh A, Hu J, Bandres-Ciga S. Advancing Personalized Medicine in Common Forms of Parkinson's Disease through Genetics: Current Therapeutics and the Future of Individualized Management. J Pers Med. 2021 Mar 01;11(3). doi: 10.3390/jpm11030169. PMID: 33804504; PMCID: PMC7998972.
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Organization, Clinical and Management Indicators on the First Year of Activity of an Outpatient Clinic Dedicated to the Diagnosis and Treatment of Severe Asthma in Italy.

Journal of asthma and allergy

Tognella S, Micheletto C, Roggeri A, Polese G, Artioli D, Senna G, Caminati M, Roggeri DP.
PMID: 34413653
J Asthma Allergy. 2021 Aug 13;14:1011-1018. doi: 10.2147/JAA.S309740. eCollection 2021.

PURPOSE: A Regional Technical Commission was set in 2017 by Veneto region (Italy) to provide opinions and recommendations on drug prescriptions and to implement treatment-pathway guidelines for severe asthma. In this observational study, we describe the first structured, integrated,...

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Tognella S, Micheletto C, Roggeri A, et al. Organization, Clinical and Management Indicators on the First Year of Activity of an Outpatient Clinic Dedicated to the Diagnosis and Treatment of Severe Asthma in Italy. J Asthma Allergy. 2021;14:1011-1018doi: 10.2147/JAA.S309740.
Tognella, S., Micheletto, C., Roggeri, A., Polese, G., Artioli, D., Senna, G., Caminati, M., & Roggeri, D. P. (2021). Organization, Clinical and Management Indicators on the First Year of Activity of an Outpatient Clinic Dedicated to the Diagnosis and Treatment of Severe Asthma in Italy. Journal of asthma and allergy, 141011-1018. https://doi.org/10.2147/JAA.S309740
Tognella, Silvia, et al. "Organization, Clinical and Management Indicators on the First Year of Activity of an Outpatient Clinic Dedicated to the Diagnosis and Treatment of Severe Asthma in Italy." Journal of asthma and allergy vol. 14 (2021): 1011-1018. doi: https://doi.org/10.2147/JAA.S309740
Tognella S, Micheletto C, Roggeri A, Polese G, Artioli D, Senna G, Caminati M, Roggeri DP. Organization, Clinical and Management Indicators on the First Year of Activity of an Outpatient Clinic Dedicated to the Diagnosis and Treatment of Severe Asthma in Italy. J Asthma Allergy. 2021 Aug 13;14:1011-1018. doi: 10.2147/JAA.S309740. eCollection 2021. PMID: 34413653; PMCID: PMC8370491.
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Lower Urinary Tract Symptoms in Myasthenia Gravis.

Case reports in neurology

Tateno F, Sakakibara R, Aiba Y.
PMID: 34413752
Case Rep Neurol. 2021 Jul 20;13(2):490-498. doi: 10.1159/000514825. eCollection 2021.

It remains uncertain to what extent lower urinary tract (LUT) symptom (LUTS) is a comorbidity of myasthenia gravis (MG). We prospectively administered a LUTS questionnaire devised for detecting neurogenic pelvic organ dysfunction (not validated) in an MG group and...

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Tateno F, Sakakibara R, Aiba Y. Lower Urinary Tract Symptoms in Myasthenia Gravis. Case Rep Neurol. 2021;13(2):490-498doi: 10.1159/000514825.
Tateno, F., Sakakibara, R., & Aiba, Y. (2021). Lower Urinary Tract Symptoms in Myasthenia Gravis. Case reports in neurology, 13(2), 490-498. https://doi.org/10.1159/000514825
Tateno, Fuyuki, et al. "Lower Urinary Tract Symptoms in Myasthenia Gravis." Case reports in neurology vol. 13,2 (2021): 490-498. doi: https://doi.org/10.1159/000514825
Tateno F, Sakakibara R, Aiba Y. Lower Urinary Tract Symptoms in Myasthenia Gravis. Case Rep Neurol. 2021 Jul 20;13(2):490-498. doi: 10.1159/000514825. eCollection 2021. PMID: 34413752; PMCID: PMC8339478.
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Insulin's actions on vascular tissues: Physiological effects and pathophysiological contributions to vascular complications of diabetes.

Molecular metabolism

Fu J, Yu MG, Li Q, Park K, King GL.
PMID: 33878400
Mol Metab. 2021 Oct;52:101236. doi: 10.1016/j.molmet.2021.101236. Epub 2021 Apr 18.

BACKGROUND: Insulin has been demonstrated to exert direct and indirect effects on vascular tissues. Its actions in vascular cells are mediated by two major pathways: the insulin receptor substrate 1/2-phosphoinositide-3 kinase/Akt (IRS1/2/PI3K/Akt) pathway and the Src/mitogen-activated protein kinase (MAPK)...

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Fu J, Yu MG, Li Q, et al. Insulin's actions on vascular tissues: Physiological effects and pathophysiological contributions to vascular complications of diabetes. Mol Metab. 2021;52:101236doi: 10.1016/j.molmet.2021.101236.
Fu, J., Yu, M. G., Li, Q., Park, K., & King, G. L. (2021). Insulin's actions on vascular tissues: Physiological effects and pathophysiological contributions to vascular complications of diabetes. Molecular metabolism, 52101236. https://doi.org/10.1016/j.molmet.2021.101236
Fu, Jialin, et al. "Insulin's actions on vascular tissues: Physiological effects and pathophysiological contributions to vascular complications of diabetes." Molecular metabolism vol. 52 (2021): 101236. doi: https://doi.org/10.1016/j.molmet.2021.101236
Fu J, Yu MG, Li Q, Park K, King GL. Insulin's actions on vascular tissues: Physiological effects and pathophysiological contributions to vascular complications of diabetes. Mol Metab. 2021 Oct;52:101236. doi: 10.1016/j.molmet.2021.101236. Epub 2021 Apr 18. PMID: 33878400; PMCID: PMC8513152.
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Stem Cells in the Path of Light, from Corneal to Retinal Reconstruction.

Biomedicines

Samoila O, Samoila L.
PMID: 34440077
Biomedicines. 2021 Jul 23;9(8). doi: 10.3390/biomedicines9080873.

The future of eye reconstruction invariably includes stem cells transplantation. Corneal limbus, corneal stroma, trabeculum, retinal cells, optic nerve, and all structures that are irreversibly damaged and have no means to be repaired or replaced, through conventional treatment or...

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Samoila O, Samoila L. Stem Cells in the Path of Light, from Corneal to Retinal Reconstruction. Biomedicines. 2021;9(8)doi: 10.3390/biomedicines9080873.
Samoila, O., & Samoila, L. (2021). Stem Cells in the Path of Light, from Corneal to Retinal Reconstruction. Biomedicines, 9(8), . https://doi.org/10.3390/biomedicines9080873
Samoila, Ovidiu, and Samoila, Lacramioara. "Stem Cells in the Path of Light, from Corneal to Retinal Reconstruction." Biomedicines vol. 9,8 (2021). doi: https://doi.org/10.3390/biomedicines9080873
Samoila O, Samoila L. Stem Cells in the Path of Light, from Corneal to Retinal Reconstruction. Biomedicines. 2021 Jul 23;9(8). doi: 10.3390/biomedicines9080873. PMID: 34440077; PMCID: PMC8389604.
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Modulation of the immune response by heterogeneous monocytes and dendritic cells in lung cancer.

World journal of clinical oncology

Kwiecień I, Rutkowska E, Raniszewska A, Rzepecki P, Domagała-Kulawik J.
PMID: 34909393
World J Clin Oncol. 2021 Nov 24;12(11):966-982. doi: 10.5306/wjco.v12.i11.966.

Different subpopulations of monocytes and dendritic cells (DCs) may have a key impact on the modulation of the immune response in malignancy. In this review, we summarize the monocyte and DCs heterogeneity and their function in the context of...

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Kwiecień I, Rutkowska E, Raniszewska A, et al. Modulation of the immune response by heterogeneous monocytes and dendritic cells in lung cancer. World J Clin Oncol. 2021;12(11):966-982doi: 10.5306/wjco.v12.i11.966.
Kwiecień, I., Rutkowska, E., Raniszewska, A., Rzepecki, P., & Domagała-Kulawik, J. (2021). Modulation of the immune response by heterogeneous monocytes and dendritic cells in lung cancer. World journal of clinical oncology, 12(11), 966-982. https://doi.org/10.5306/wjco.v12.i11.966
Kwiecień, Iwona, et al. "Modulation of the immune response by heterogeneous monocytes and dendritic cells in lung cancer." World journal of clinical oncology vol. 12,11 (2021): 966-982. doi: https://doi.org/10.5306/wjco.v12.i11.966
Kwiecień I, Rutkowska E, Raniszewska A, Rzepecki P, Domagała-Kulawik J. Modulation of the immune response by heterogeneous monocytes and dendritic cells in lung cancer. World J Clin Oncol. 2021 Nov 24;12(11):966-982. doi: 10.5306/wjco.v12.i11.966. PMID: 34909393; PMCID: PMC8641004.
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Strategies and Therapies for Wound Healing: A Review.

Current drug targets

Chopra H, Kumar S, Singh I.
PMID: 33858310
Curr Drug Targets. 2021 Apr 14; doi: 10.2174/1389450122666210415101218. Epub 2021 Apr 14.

Wound healing is the complex and a never-ending process that involves numerous mediators, enzymatic cascades that are directly or indirectly involved in the mechanism. So, it becomes necessary to closely examine critical factors such as gaseous exchange, a moist...

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Chopra H, Kumar S, Singh I. Strategies and Therapies for Wound Healing: A Review. Curr Drug Targets. 2021;doi: 10.2174/1389450122666210415101218.
Chopra, H., Kumar, S., & Singh, I. (2021). Strategies and Therapies for Wound Healing: A Review. Current drug targets, . https://doi.org/10.2174/1389450122666210415101218
Chopra, Hitesh, et al. "Strategies and Therapies for Wound Healing: A Review." Current drug targets vol. (2021). doi: https://doi.org/10.2174/1389450122666210415101218
Chopra H, Kumar S, Singh I. Strategies and Therapies for Wound Healing: A Review. Curr Drug Targets. 2021 Apr 14; doi: 10.2174/1389450122666210415101218. Epub 2021 Apr 14. PMID: 33858310.
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Cadiolide analogues and their precursors as new inhibitors of bacterial quorum sensing and biofilm formation.

Bioorganic & medicinal chemistry letters

Moreira TA, Antolínez IV, Valença WO, Roy S, Barbosa LCA, Ren D.
PMID: 34896477
Bioorg Med Chem Lett. 2021 Dec 09;57:128498. doi: 10.1016/j.bmcl.2021.128498. Epub 2021 Dec 09.

Bacterial quorum sensing (QS) and biofilm formation are promising targets for developing new therapies to treat chronic infections. Herein, we report the stereoselective synthesis of 18 new analogs of natural cadiolides. Among the new compounds, substances 8b, 8f, 8i,...

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Moreira TA, Antolínez IV, Valença WO, et al. Cadiolide analogues and their precursors as new inhibitors of bacterial quorum sensing and biofilm formation. Bioorg Med Chem Lett. 2021;57:128498doi: 10.1016/j.bmcl.2021.128498.
Moreira, T. A., Antolínez, I. V., Valença, W. O., Roy, S., Barbosa, L. C. A., & Ren, D. (2021). Cadiolide analogues and their precursors as new inhibitors of bacterial quorum sensing and biofilm formation. Bioorganic & medicinal chemistry letters, 57128498. https://doi.org/10.1016/j.bmcl.2021.128498
Moreira, Thais A, et al. "Cadiolide analogues and their precursors as new inhibitors of bacterial quorum sensing and biofilm formation." Bioorganic & medicinal chemistry letters vol. 57 (2021): 128498. doi: https://doi.org/10.1016/j.bmcl.2021.128498
Moreira TA, Antolínez IV, Valença WO, Roy S, Barbosa LCA, Ren D. Cadiolide analogues and their precursors as new inhibitors of bacterial quorum sensing and biofilm formation. Bioorg Med Chem Lett. 2021 Dec 09;57:128498. doi: 10.1016/j.bmcl.2021.128498. Epub 2021 Dec 09. PMID: 34896477.
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Neuroinflammation predicts disease progression in progressive supranuclear palsy.

Journal of neurology, neurosurgery, and psychiatry

Malpetti M, Passamonti L, Jones PS, Street D, Rittman T, Fryer TD, Hong YT, Vàsquez Rodriguez P, Bevan-Jones WR, Aigbirhio FI, O'Brien JT, Rowe JB.
PMID: 33731439
J Neurol Neurosurg Psychiatry. 2021 Jul;92(7):769-775. doi: 10.1136/jnnp-2020-325549. Epub 2021 Mar 17.

INTRODUCTION: In addition to tau pathology and neuronal loss, neuroinflammation occurs in progressive supranuclear palsy (PSP). However, the prognostic value of the in vivo imaging markers for these processes in PSP remains unclear. We test the primary hypothesis that...

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Malpetti M, Passamonti L, Jones PS, et al. Neuroinflammation predicts disease progression in progressive supranuclear palsy. J Neurol Neurosurg Psychiatry. 2021;92(7):769-775doi: 10.1136/jnnp-2020-325549.
Malpetti, M., Passamonti, L., Jones, P. S., Street, D., Rittman, T., Fryer, T. D., Hong, Y. T., Vàsquez Rodriguez, P., Bevan-Jones, W. R., Aigbirhio, F. I., O'Brien, J. T., & Rowe, J. B. (2021). Neuroinflammation predicts disease progression in progressive supranuclear palsy. Journal of neurology, neurosurgery, and psychiatry, 92(7), 769-775. https://doi.org/10.1136/jnnp-2020-325549
Malpetti, Maura, et al. "Neuroinflammation predicts disease progression in progressive supranuclear palsy." Journal of neurology, neurosurgery, and psychiatry vol. 92,7 (2021): 769-775. doi: https://doi.org/10.1136/jnnp-2020-325549
Malpetti M, Passamonti L, Jones PS, Street D, Rittman T, Fryer TD, Hong YT, Vàsquez Rodriguez P, Bevan-Jones WR, Aigbirhio FI, O'Brien JT, Rowe JB. Neuroinflammation predicts disease progression in progressive supranuclear palsy. J Neurol Neurosurg Psychiatry. 2021 Jul;92(7):769-775. doi: 10.1136/jnnp-2020-325549. Epub 2021 Mar 17. PMID: 33731439; PMCID: PMC7611006.
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Biological Heterogeneity of Chondrosarcoma: From (Epi) Genetics through Stemness and Deregulated Signaling to Immunophenotype.

Cancers

Zając A, Król SK, Rutkowski P, Czarnecka AM.
PMID: 33804155
Cancers (Basel). 2021 Mar 15;13(6). doi: 10.3390/cancers13061317.

Chondrosarcoma (ChS) is a primary malignant bone tumor. Due to its heterogeneity in clinical outcomes and resistance to chemo- and radiotherapies, there is a need to develop new potential therapies and molecular targets of drugs. Many genes and pathways...

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Zając A, Król SK, Rutkowski P, et al. Biological Heterogeneity of Chondrosarcoma: From (Epi) Genetics through Stemness and Deregulated Signaling to Immunophenotype. Cancers (Basel). 2021;13(6)doi: 10.3390/cancers13061317.
Zając, A., Król, S. K., Rutkowski, P., & Czarnecka, A. M. (2021). Biological Heterogeneity of Chondrosarcoma: From (Epi) Genetics through Stemness and Deregulated Signaling to Immunophenotype. Cancers, 13(6), . https://doi.org/10.3390/cancers13061317
Zając, Agnieszka, et al. "Biological Heterogeneity of Chondrosarcoma: From (Epi) Genetics through Stemness and Deregulated Signaling to Immunophenotype." Cancers vol. 13,6 (2021). doi: https://doi.org/10.3390/cancers13061317
Zając A, Król SK, Rutkowski P, Czarnecka AM. Biological Heterogeneity of Chondrosarcoma: From (Epi) Genetics through Stemness and Deregulated Signaling to Immunophenotype. Cancers (Basel). 2021 Mar 15;13(6). doi: 10.3390/cancers13061317. PMID: 33804155; PMCID: PMC8001927.
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Showing 9973 to 9984 of 67709 entries