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Showing 25 to 36 of 470 entries
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Treatment of Atypical Ulnar Fractures Associated with Long-Term Bisphosphonate Therapy for Osteoporosis: Autogenous Bone Graft with Internal Fixation.

Case reports in orthopedics

Shimada Y, Ishikawa T, Endo J, Katsuragi J, Kotani T, Kiuchi H, Kuniyoshi K, Ohtori S.
PMID: 29318073
Case Rep Orthop. 2017;2017:8602573. doi: 10.1155/2017/8602573. Epub 2017 Nov 29.

Long-term bisphosphonate use has been suggested to result in decreased bone remodelling and an increased risk of atypical fractures. Fractures of this nature commonly occur in the femur, and relatively few reports exist to show that they occur in...

Pretreatment of daily teriparatide enhances the increase of bone mineral density in cortical bones by denosumab therapy.

Therapeutics and clinical risk management

Kamimura M, Taguchi A, Nakamura Y, Koiwai H, Ikegami S, Uchiyama S, Kato H.
PMID: 29662314
Ther Clin Risk Manag. 2018 Apr 03;14:637-642. doi: 10.2147/TCRM.S154686. eCollection 2018.

BACKGROUND: While it is well known that teriparatide (TPTD) increases bone mineral density (BMD) in osteoporotic patients, it is unknown whether TPTD pretreatment affects BMD after denosumab (DMAb) therapy.METHODS: Fifty-seven patients in TPTD-pretreated group and 35 patients in DMAb-alone...

Enhanced bone healing and decreased pain in sacral insufficiency fractures after teriparatide treatment: retrospective clinical-based observational study.

Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases

Kasukawa Y, Miyakoshi N, Ebina T, Hongo M, Ishikawa Y, Kudo D, Nozaka K, Shimada Y.
PMID: 29263722
Clin Cases Miner Bone Metab. 2017 May-Aug;14(2):140-145. doi: 10.11138/ccmbm/2017.14.1.140. Epub 2017 Oct 25.

The purpose of this retrospective clinical-based observational study was to evaluate the effects of teriparatide (TPTD) on clinical outcomes and radiologic findings of sacral insufficiency fractures (SIFs). Seven elderly women with SIFs received TPTD for at least 6 months....

Histological study of atraumatic periprosthetic fractures: does atypical periprosthetic fracture exist?.

Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases

Bottai V, De Paola G, Celli F, Lazzerini I, Ortenzi V, Naccarato AG, Guido G, Capanna R, Giannotti S.
PMID: 29263721
Clin Cases Miner Bone Metab. 2017 May-Aug;14(2):136-139. doi: 10.11138/ccmbm/2017.14.1.136. Epub 2017 Oct 25.

PURPOSE: Is it possible a correlation between some periprosthetic femoral fractures and atypical fractures?CASE: We present a case of a 77-year-old woman with atypical periprosthetic femoral fracture. The patient had a history of long-term bisphosphonate use. We performed an...

Anabolic treatment for osteoporosis: teriparatide.

Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases

Eastell R, Walsh JS.
PMID: 29263728
Clin Cases Miner Bone Metab. 2017 May-Aug;14(2):173-178. doi: 10.11138/ccmbm/2017.14.1.173. Epub 2017 Oct 25.

Teriparatide is a safe and effective anabolic treatment for osteoporosis. In postmenopausal women, it increases BMD and decreases vertebral fractures by about 70% and non-vertebral fractures by about 45% (although there is no evidence that it prevents hip fractures)....

The challenges of diagnosing osteoporosis and the limitations of currently available tools.

Clinical diabetes and endocrinology

Choksi P, Jepsen KJ, Clines GA.
PMID: 29862042
Clin Diabetes Endocrinol. 2018 May 29;4:12. doi: 10.1186/s40842-018-0062-7. eCollection 2018.

Dual-energy X-ray absorptiometry (DXA) was the first imaging tool widely utilized by clinicians to assess fracture risk, especially in postmenopausal women. The development of DXA nearly coincided with the availability of effective osteoporosis medications. Although osteoporosis in adults is...

Periprosthetic Femoral Stress Fracture After Bisphosphonate Treatment Resulting in Nonunion Successfully Treated with Teriparatide: A Case Report.

JBJS case connector

Ramani A, Wagner R.
PMID: 29252670
JBJS Case Connect. 2016 Apr-Jun;6(2):e37. doi: 10.2106/JBJS.CC.15.00172.

CASE: We present the case of a postmenopausal osteoporotic woman, treated with bisphosphonates, who developed a stress fracture at the tip of a revision femoral component, resulting in nonunion after several operative treatment attempts. The nonunion healed after 7...

Peri-prosthetic humeral non-union: Where biology meets bio-mechanic. A case report.

International journal of surgery case reports

Emanuele C, Leonardo P, Gianfilippo C, Matteo A, Doria C.
PMID: 28826070
Int J Surg Case Rep. 2017;39:102-105. doi: 10.1016/j.ijscr.2017.08.001. Epub 2017 Aug 05.

INTRODUCTION: The worldwide incidence of traumatic fractures has been growing over the last years due to the progressive aging of the population. Today, the increase of arthroplasty procedures in orthopaedic surgery is related to a high rate of peri-prosthetic...

Successful Spinal Fixation Surgery Following Teriparatide Treatment in an Adolescent Boy with Severe Osteoporosis and Progressive Kyphoscoliosis: A Case Report.

JBJS case connector

Oberdorfer E, Polly D, Larson-Ode K, Smith-Wright D, Guidera K, Neglia JP, Polgreen LE.
PMID: 29252757
JBJS Case Connect. 2014 Oct/Dec/Nov;4(4):e89. doi: 10.2106/JBJS.CC.M.00296.

No abstract available.

Treatment of Osteoporosis: Unmet Needs and Emerging Solutions.

Journal of bone metabolism

Langdahl BL, Andersen JD.
PMID: 30237992
J Bone Metab. 2018 Aug;25(3):133-140. doi: 10.11005/jbm.2018.25.3.133. Epub 2018 Aug 31.

Efficient therapies are available for the treatment of osteoporosis, however, there are still unmet needs. Anti-resorptive therapies only increase bone mineral density to a certain extent and reduce the risk of non-vertebral fractures by 20%, only one anabolic option...

A Feasibility Study to Evaluate .

Avicenna journal of medical biotechnology

Karimi M, Behzadian F, Rouhaninejad H, Yari S.
PMID: 30090207
Avicenna J Med Biotechnol. 2018 Jul-Sep;10(3):147-151.

BACKGROUND: Biosynthetic teriparatide (1-34) (TPD) is a N-terminally truncated version of human parathyroid hormone (hPTH). The recombinant form of this polypeptide has been expressed in METHODS: A codon optimized gene containing TPD open reading frame carrying enterokinase site in...

An unexpected healing of an established non union of the radial neck through teriparatide: A case report and review of literature.

Journal of clinical orthopaedics and trauma

Garg B, Batra S, Dixit V.
PMID: 29628709
J Clin Orthop Trauma. 2018 Mar;9:S103-S105. doi: 10.1016/j.jcot.2017.10.015. Epub 2017 Oct 27.

No abstract available.

Showing 25 to 36 of 470 entries