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Showing 25 to 36 of 55 entries
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Past year use or misuse of an opioid is associated with use of a sedative-hypnotic medication: a NSDUH study.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Tubbs AS, Ghani SB, Naps M, Grandner MA, Stein MD, Chakravorty S.
PMID: 34666879
J Clin Sleep Med. 2021 Oct 20; doi: 10.5664/jcsm.9724. Epub 2021 Oct 20.

STUDY OBJECTIVES: Prescription use and misuse of opioids are linked to greater sleep disturbance. However, there are limited data on the prevalence of sedative-hypnotic medication use among persons who use opioids. Therefore, this study examined whether past year sedative-hypnotic...

Medication not accounted for in hospital electronic medication administration records: a retrospective observational study.

The Medical journal of Australia

Walker K, Harding AM, Tran J, Wembridge P, Garrett K, MacMillan K, Rofe O, Jones N, Taylor D.
PMID: 34970740
Med J Aust. 2021 Dec 30; doi: 10.5694/mja2.51370. Epub 2021 Dec 30.

OBJECTIVE: To determine the nature, extent, and cost of discrepancies between the quantities of medications supplied to medical departments and administered to patients in public hospitals.DESIGN: Multicentre, retrospective observational study; analysis of electronic pharmacy drug management system (medication supply)...

Proton pump inhibitors associated with rapid eye movement sleep behaviour disorder.

BMJ case reports

Jayasekara R, Smith I.
PMID: 34972777
BMJ Case Rep. 2021 Dec 31;14(12). doi: 10.1136/bcr-2021-246469.

We present the case of a 65-year-old woman diagnosed with rapid eye movement sleep behaviour disorder (REMBD) based on typical symptoms and confirmed with an inpatient polysomnogram. She was prescribed clonazepam and later temazepam but continued to have intrusive...

Rhabdomyolysis in Clozapine Overdose.

Drug safety - case reports

Jansman FG, Crommelin HA, van Hout FJ, Meulenbelt J.
PMID: 27747721
Drug Saf Case Rep. 2015 Dec;2(1):9. doi: 10.1007/s40800-015-0011-7.

CONTEXT: Clozapine is used for decennia for the treatment of schizophrenia. Agranulocytosis, diabetic ketoacidosis, gastrointestinal hypomotility, and myocarditis are well-known adverse effects of clozapine, which are sometimes life threatening. Here we report a case of rhabdomyolysis upon an acute...

Proton pump inhibitors associated with rapid eye movement sleep behaviour disorder.

BMJ case reports

Jayasekara R, Smith I.
PMID: 34972777
BMJ Case Rep. 2021 Dec 31;14(12). doi: 10.1136/bcr-2021-246469.

We present the case of a 65-year-old woman diagnosed with rapid eye movement sleep behaviour disorder (REMBD) based on typical symptoms and confirmed with an inpatient polysomnogram. She was prescribed clonazepam and later temazepam but continued to have intrusive...

Fatigue in Aviation: Safety Risks, Preventive Strategies and Pharmacological Interventions.

Frontiers in physiology

Wingelaar-Jagt YQ, Wingelaar TT, Riedel WJ, Ramaekers JG.
PMID: 34552504
Front Physiol. 2021 Sep 06;12:712628. doi: 10.3389/fphys.2021.712628. eCollection 2021.

Fatigue poses an important safety risk to civil and military aviation. In addition to decreasing performance in-flight (chronic) fatigue has negative long-term health effects. Possible causes of fatigue include sleep loss, extended time awake, circadian phase irregularities and work...

Repeat prescribing: which diagnoses, which drugs?.

Pharmacoepidemiology and drug safety

Connolly JP, McGavock H.
PMID: 19025833
Pharmacoepidemiol Drug Saf. 2000 Jul;9(4):305-11. doi: 10.1002/1099-1557(200007/08)9:4<305::AID-PDS513>3.0.CO;2-O.

Background-Repeat prescribing should be limited to drugs which are to be prescribed on a long-term basis to patients whose conditions are stable. Early studies were based on small sample sizes. The definition of repeat prescribing has not been consistent...

Mass Spectra and Cross-Contribution of Ion Intensity Between Drug Analytes and Their Isotopically Labelled Analogs - Benzodiazepines and Their Derivatives.

Forensic science review

Wang SM, Chen BG, Wu MY, Liu RH, Lewis RJ, Ritter RM, Canfield DV.
PMID: 26242324
Forensic Sci Rev. 2009 Jul;21(2):69-144.

With GC-MS as the preferred method and isotopically labeled analogs (ILAs) of the analytes as the internal standards (ISs) of choice for quantitative determination of drugs/metabolites in biological specimens, one important aspect associated with chemical derivatization (CD) is that...

HPLC analysis and pharmacokinetics of the enantiomers of R,S-oxazepam and R,S-temazepam with their corresponding glucuronide conjugates in urine and plasma of man.

Acta neuropsychiatrica

Vree TB, Baars AM, Wuis EW.
PMID: 26952555
Acta Neuropsychiatr. 1990 Dec;2(4):95-100. doi: 10.1017/S0924270800034505.

R,S-Oxazepam and R,S-temazepam can be separated in their enantiomers by means of a chiral AGP column. The corresponding R- and S-glucuronide conjugates can be separated on a normal reversed-phase C18 column. Man conjugates the S-enantiomer of oxazepam and temazepam...

Temazepam misused in spite of new formula.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)

[No authors listed]
PMID: 27680140
Nurs Stand. 1991 Dec 11;6(12):15. doi: 10.7748/ns.6.12.15.s35.

Despite a change in the formulation of the drug temazepam, doctors from Charing Cross Hospital have reported that it continues to be injected by intravenous drug abusers.

Normalizing sleep quality disturbed by psychiatric polypharmacy: a single patient open trial (SPOT).

F1000Research

Magnuson V, Wang Y, Schork N.
PMID: 28781744
F1000Res. 2016 Feb 03;5:132. doi: 10.12688/f1000research.7694.2. eCollection 2016.

There is a growing interest in personalized and preventive medicine initiatives that leverage serious patient engagement, such as those initiated and pursued among participants in the quantified-self movement. However, many of the self-assessments that result are not rooted in...

Contamination profiles, mass loadings, and sewage epidemiology of neuropsychiatric and illicit drugs in wastewater and river waters from a community in the Midwestern United States.

The Science of the total environment

Skees AJ, Foppe KS, Loganathan B, Subedi B.
PMID: 29727969
Sci Total Environ. 2018 Aug 01;631:1457-1464. doi: 10.1016/j.scitotenv.2018.03.060. Epub 2018 Mar 28.

In this study, residues of the neuropsychiatric and illicit drugs including stimulants, opioids, hallucinogens, antischizophrenics, sedatives, and antidepressants were determined in influent and effluent samples from a small wastewater treatment plant, a receiving creek, and river waters in the...

Showing 25 to 36 of 55 entries