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Showing 13 to 24 of 55 entries
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Development of an Analytical Method for Detection of Anesthetics and Sedatives in Fish.

Journal of AOAC International

Hong S, Kwon N, Kang HS, Jang E, Kim H, Han E.
PMID: 34894253
J AOAC Int. 2021 Dec 11; doi: 10.1093/jaoacint/qsab155. Epub 2021 Dec 11.

BACKGROUND: Anesthetics and sedatives are frequently used to prevent abrasions caused by stress and facilitate fish management. However, drug residues may persist and cause changes in fish conditions and induce side effects. In addition, drugs that are not permitted...

Prevalence and concentrations of sedative-hypnotic drugs in blood of drivers involved in road traffic crashes in the Padova region of Italy - not so easy to interpret.

Forensic science international

Favretto D, Visentin S, Jones AW.
PMID: 34814082
Forensic Sci Int. 2021 Nov 06;330:111097. doi: 10.1016/j.forsciint.2021.111097. Epub 2021 Nov 06.

BACKGROUND & OBJECTIVES: This study reports the prevalence and concentrations of sedative-hypnotic drugs as exemplified by benzodiazepines (BZD) and zolpidem (Z-hypnotic) in blood samples from drivers involved in road traffic accidents (RTA) in the Padova region of Italy. Another...

Effects of temazepam on memory and psychomotor performance: a dose-response study.

Human psychopharmacology

Begg A, Drummond G, Tiplady B.
PMID: 12404556
Hum Psychopharmacol. 2001 Aug;16(6):475-480. doi: 10.1002/hup.321.

In a randomised, three-period crossover study, psychomotor performance and memory were tested and mood assessed for 3 h after single doses of placebo (PL), 20 mg temazepam (T20) or 30 mg temazepam (T30) were given to six healthy females...

Racemization of oxazepam and chiral 1,4-benzodiazepines. DFT study of the reaction mechanism in aqueous solution.

Organic & biomolecular chemistry

Hok L, BoŽičević L, Sremec H, Šakić D, Vrček V.
PMID: 30676597
Org Biomol Chem. 2019 Feb 06;17(6):1471-1479. doi: 10.1039/c8ob02991a.

The tranquilizer and hypnotic drug oxazepam undergoes the racemization process in aqueous medium, which is relevant for its pharmacological profile. The experimental barrier value (ΔG‡298 ≈ 91 kJ mol-1) was determined earlier, but the exact mechanism of enantiomerization is...

Is there a problem with benzodiazepine prescribing in maritime Canada?.

Canadian family physician Medecin de famille canadien

Sketris IS, Maccara ME, Purkis IE, Curry L.
PMID: 21274169
Can Fam Physician. 1985 Sep;31:1591-6.

The benzodiazepine prescribing habits of 64 maritime doctors were studied through collection and examination of carbon copies of all prescriptions over a 22 week period. Diazepam was the most frequently prescribed anxiolytic benzodiazepine, followed by chlordiazepoxide, then oxazepam. These...

Insomnia in Psychiatric Patients - the Hypnotic Effect and Withdrawal Problems of Zopiclone and Temazepam: Dobbins SE, Rhone-Poulenc Rorer Ltd., Rainham Road South, Dagenham, Essex, RM10 7XS.

Journal of psychopharmacology (Oxford, England)

[No authors listed]
PMID: 22291315
J Psychopharmacol. 1992 Jan;6(1):132. doi: 10.1177/026988119200600187.

No abstract available.

Tuberulous Meningitis masked by Temazepam Overdose.

Acute medicine

Rajendram R, Jennings A, Ehtisham J.
PMID: 21611597
Acute Med. 2007;6(2):73-4.

A 47 year old Chinese businessman was found unconscious at home following an overdose of 280 mg temazepam. He was found by his sister who had visited because he had not returned her telephone calls for several weeks. He...

Metabolism of Diazepam and Ethosuximide in rats with malaria and endotoxin-induced fever.

African journal of health sciences

Kokwaro GO, Indalo AA.
PMID: 17451291
Afr J Health Sci. 1996 Feb;3(1):22-6.

We have investigated the effects of malaria infection with rodent parasite Plasmodium berghei and fever induced by Escherischia coli endotoxin on the metabolism of diazepam to temazepam by rat liver microsomes, and on the clearance of ethosuximide in vivo...

Benzodiazepine use among heroin users in Sydney: patterns of use, availability and procurement.

Drug and alcohol review

Ross J, Darke S, Hall W.
PMID: 16203378
Drug Alcohol Rev. 1996 Sep;15(3):237-43. doi: 10.1080/09595239600185971.

A sample of 210 heroin users who had used benzodiazepines during the preceding 6 months were interviewed about their benzodiazepine use. Forty-one percent of the sample reported having used benzodiazepines more than once a week during the 6 months...

Driving Performance Under Treatment of Most Frequently Prescribed Drugs for Mental Disorders: A Systematic Review of Patient Studies.

The international journal of neuropsychopharmacology

Brunnauer A, Herpich F, Zwanzger P, Laux G.
PMID: 34038545
Int J Neuropsychopharmacol. 2021 Sep 21;24(9):679-693. doi: 10.1093/ijnp/pyab031.

BACKGROUND: Mobility is important for daily life functioning, with particular challenges regarding road safety under pharmacological treatment in patients with a psychiatric disease.METHODS: According to PRISMA guidelines, a systematic literature search on PubMed database (January 1970 to December 2020)...

An Emulation of Randomized Trials of Administrating Benzodiazepines in PTSD Patients for Outcomes of Suicide-Related Events.

Journal of clinical medicine

Gilbert M, Dinh La A, Romulo Delapaz N, Kenneth Hor W, Fan P, Qi X, Guo X, Ying J, Wang L.
PMID: 33138006
J Clin Med. 2020 Oct 29;9(11). doi: 10.3390/jcm9113492.

Benzodiazepines is a class of medications frequently prescribed to patients with post-traumatic stress disorder. Patients with PTSD have a notable increased risk of suicide compared to the general population. These medications have been theorized to increase suicidality and pose...

Prevalence and concentrations of sedative-hypnotic drugs in blood of drivers involved in road traffic crashes in the Padova region of Italy - not so easy to interpret.

Forensic science international

Favretto D, Visentin S, Jones AW.
PMID: 34814082
Forensic Sci Int. 2022 Jan;330:111097. doi: 10.1016/j.forsciint.2021.111097. Epub 2021 Nov 06.

BACKGROUND & OBJECTIVES: This study reports the prevalence and concentrations of sedative-hypnotic drugs as exemplified by benzodiazepines (BZD) and zolpidem (Z-hypnotic) in blood samples from drivers involved in road traffic accidents (RTA) in the Padova region of Italy. Another...

Showing 13 to 24 of 55 entries