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Showing 13 to 24 of 7672 entries
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Ameliorative Effects of Chloroform Fraction of Cocos nucifera L. Husk Fiber Against Cisplatin-induced Toxicity in Rats.

Pharmacognosy research

Adaramoye OA, Azeez AF, Ola-Davies OE.
PMID: 27034598
Pharmacognosy Res. 2016 Apr-Jun;8(2):89-96. doi: 10.4103/0974-8490.172658.

BACKGROUND: Cisplatin (Cis) is used in the treatment of solid tumors and is known to elicit serious side effects.OBJECTIVE: The present study investigated the protective effects of chloroform fraction of Cocos nucifera husk fiber (CFCN) against Cis-induced organs' damage...

Therapeutic Potential of HGF-Expressing Human Umbilical Cord Mesenchymal Stem Cells in Mice with Acute Liver Failure.

International journal of hepatology

Tang Y, Li Q, Meng F, Huang X, Li C, Zhou X, Zeng X, He Y, Liu J, Hu X, Hu JF, Li T.
PMID: 27057357
Int J Hepatol. 2016;2016:5452487. doi: 10.1155/2016/5452487. Epub 2016 Feb 28.

Human umbilical cord-derived mesenchymal stem cells (UCMSCs) are particularly attractive cells for cellular and gene therapy in acute liver failure (ALF). However, the efficacy of this cell therapy in animal studies needs to be significantly improved before it can...

The role of reactive oxygen species in myocardial redox signaling and regulation.

Annals of translational medicine

Moris D, Spartalis M, Tzatzaki E, Spartalis E, Karachaliou GS, Triantafyllis AS, Karaolanis GI, Tsilimigras DI, Theocharis S.
PMID: 28861421
Ann Transl Med. 2017 Aug;5(16):324. doi: 10.21037/atm.2017.06.17.

Reactive oxygen species (ROS) are subcellular messengers in gene regulatory and signal transduction pathways. In pathological situations, ROS accumulate due to excessive production or insufficient degradation, leading to oxidative stress (OS). OS causes oxidation of DNA, membranes, cellular lipids,...

Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis.

OncoTargets and therapy

Lien CY, Chuang TY, Hsu CH, Lin CL, Wang SE, Sheu SJ, Chien CT, Wu CH.
PMID: 26060405
Onco Targets Ther. 2015 May 26;8:1193-210. doi: 10.2147/OTT.S82936. eCollection 2015.

OBJECTIVE: This study aimed to investigate whether the herbal formula B307 could alleviate doxorubicin (DOX)-induced acute cardiotoxicity. If so, we further unraveled possible molecular mechanisms of cardiac protection under treatment with the herbal formula B307.METHODS: Before the animal experiment,...

Coarse-Graining the Accessible Surface and the Electrostatics of Proteins for Protein-Protein Interactions.

Journal of chemical theory and computation

Pizzitutti F, Marchi M, Borgis D.
PMID: 26627629
J Chem Theory Comput. 2007 Sep;3(5):1867-76. doi: 10.1021/ct700121n.

This study is concerned with the development and test of a coarse-grained representation specifically constructed for proteins and peptides, where each amino acid of the sequence is represented by a charged dipolar sphere. The model was parametrized from the...

Effects of dietary marigold extract supplementation on growth performance, pigmentation, antioxidant capacity and meat quality in broiler chickens.

Asian-Australasian journal of animal sciences

Wang S, Zhang L, Li J, Cong J, Gao F, Zhou G.
PMID: 27282969
Asian-Australas J Anim Sci. 2017 Jan;30(1):71-77. doi: 10.5713/ajas.16.0075. Epub 2016 Jun 09.

OBJECTIVE: This experiment was conducted to investigate the effects of dietary supplementation with marigold extract on growth performance, pigmentation, antioxidant capacity and meat quality in broiler chickens.METHODS: A total of 320 one-day-old Arbor Acres chickens were randomly divided into...

Melatonin reduces oxidative stress and cardiovascular changes induced by stanozolol in rats exposed to swimming exercise.

The Eurasian journal of medicine

Barbosa Dos Santos G, Machado Rodrigues MJ, Gonçalves EM, Cintra Gomes Marcondes MC, Areas MA.
PMID: 25610273
Eurasian J Med. 2013 Oct;45(3):155-62. doi: 10.5152/eajm.2013.33.

OBJECTIVE: Anabolic-androgenic steroids (AAS) are nominated for clinical use to promote protein synthesis in many therapeutic conditions. However, the indiscriminate use of AAS is related to hazardous cardiac disturbances and oxidative stress. We designed a study to investigate whether...

Deep sea water improves exercise and inhibits oxidative stress in a physical fatigue mouse model.

Biomedical reports

Fan H, Tan Z, Hua Y, Huang X, Gao Y, Wu Y, Liu B, Zhou Y.
PMID: 27284418
Biomed Rep. 2016 Jun;4(6):751-757. doi: 10.3892/br.2016.651. Epub 2016 Apr 13.

Physical fatigue is extremely common and occurs daily, and is considered to be associated with oxidative stress. The diverse functions of deep sea water (DSW) have recently gained increasing attention. Previous studies have emphasized the anti-fatigue effect of DSW,...

Repeated Supramaximal Exercise-Induced Oxidative Stress: Effect of β-Alanine Plus Creatine Supplementation.

Asian journal of sports medicine

Belviranli M, Okudan N, Revan S, Balci S, Gokbel H.
PMID: 27217925
Asian J Sports Med. 2016 Mar 01;7(1):e26843. doi: 10.5812/asjsm.26843. eCollection 2016 Mar.

BACKGROUND: Carnosine is a dipeptide formed from the β-alanine and histidine amino acids and found in mainly in the brain and muscle, especially fast twitch muscle. Carnosine and creatine has an antioxidant effect and carnosine accounts for about 10%...

Combinational effect of resveratrol and atorvastatin on isoproterenol-induced cardiac hypertrophy in rats.

Journal of pharmacy & bioallied sciences

Chakraborty S, Pujani M, Haque SE.
PMID: 26229360
J Pharm Bioallied Sci. 2015 Jul-Sep;7(3):233-8. doi: 10.4103/0975-7406.160037.

INTRODUCTION: Resveratrol is a natural polyphenol present mainly in grapes. It has been shown to offer strong cardio protection in animal models due to its ability to correct lipid peroxidation and maintain antioxidants level. Atorvastatin, a HMG-CoA reductase inhibitor,...

Improvement of thoracic aortic vasoreactivity by continuous and intermittent exercise in high-fat diet-induced obese rats.

Biomedical reports

Liu H, Yang Z, Hu J, Luo Y, Zhu L, Yang H, Li G.
PMID: 26171160
Biomed Rep. 2015 Jul;3(4):527-532. doi: 10.3892/br.2015.451. Epub 2015 Apr 16.

The aim of the present study was to explore the effects of continuous and intermittent exercise on the thoracic aortic vasoreactivity and free radical metabolism in rats fed with a high-fat diet (HD). Sprague-Dawley (SD) rats were randomly divided...

Corrigendum to "Functional characterization and immune recognition of the extracellular superoxide dismutase from the human pathogenic parasite Onchocerca volvulus (OvEC-SOD)" [Acta Trop. 124 (2012) 15-26].

Acta tropica

Ajonina-Ekoti I, Ndjonka D, Tanyi MK, Wilbertz M, Younis AE, Boursou D, Kurosinski MA, Eberle R, Lüersen K, Perbandt M, Breloer M, Brattig NW, Liebau E.
PMID: 27340046
Acta Trop. 2016 Sep;161:114. doi: 10.1016/j.actatropica.2016.05.019. Epub 2016 Jun 20.

No abstract available.

Showing 13 to 24 of 7672 entries