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Showing 25 to 36 of 301 entries
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Improved Survival and Hematopoietic Differentiation of Murine Embryonic Stem Cells on Electrospun Polycaprolactone Nanofiber.

Cell journal

Dehdilani N, Shamsasenjan K, Movassaghpour A, Akbarzadehlaleh P, Amoughli Tabrizi B, Parsa H, Sabagi F.
PMID: 26862522
Cell J. 2016;17(4):629-38. doi: 10.22074/cellj.2016.3835. Epub 2016 Jan 17.

OBJECTIVE: Three-dimensional (3D) biomimetic nanofiber scaffolds have widespread ap- plications in biomedical tissue engineering. They provide a suitable environment for cel- lular adhesion, survival, proliferation and differentiation, guide new tissue formation and development, and are one of the outstanding...

A Customized Self-Assembling Peptide Hydrogel-Wrapped Stem Cell Factor Targeting Pulp Regeneration Rich in Vascular-Like Structures.

ACS omega

Mu X, Shi L, Pan S, He L, Niu Y, Wang X.
PMID: 32685822
ACS Omega. 2020 Jun 28;5(27):16568-16574. doi: 10.1021/acsomega.0c01266. eCollection 2020 Jul 14.

Pulp regeneration is to replace the inflamed/necrotic pulp tissue with regenerated pulp-like tissue to rejuvenate the teeth. Self-assembling peptide hydrogels RADA16-I (Ac-(RADA16-I)

SOX9 Stem-Cell Factor: Clinical and Functional Relevance in Cancer.

Journal of oncology

Aguilar-Medina M, Avendaño-Félix M, Lizárraga-Verdugo E, Bermúdez M, Romero-Quintana JG, Ramos-Payan R, Ruíz-García E, López-Camarillo C.
PMID: 31057614
J Oncol. 2019 Apr 01;2019:6754040. doi: 10.1155/2019/6754040. eCollection 2019.

Transcriptional and epigenetic embryonic programs can be reactivated in cancer cells. As result, a specific subset of undifferentiated cells with stem-cells properties emerges and drives tumorigenesis. Recent findings have shown that ectoderm- and endoderm-derived tissues continue expressing stem-cells related...

Expression and functional roles of the chemokine receptor CXCR7 in acute myeloid leukemia cells.

Blood research

Kim HY, Lee SY, Kim DY, Moon JY, Choi YS, Song IC, Lee HJ, Yun HJ, Kim S, Jo DY.
PMID: 26770949
Blood Res. 2015 Dec;50(4):218-26. doi: 10.5045/br.2015.50.4.218. Epub 2015 Dec 21.

BACKGROUND: The C-X-C chemokine receptor 7 (CXCR7) has been shown to be a decoy receptor for CXCR4 in certain cell types. We investigated the expression status and functional roles of CXCR7 in acute myeloid leukemia (AML) cells in vitro.METHODS:...

Interaction of Follicle-Stimulating Hormone and Stem Cell Factor to Promote Primordial Follicle Assembly in the Chicken.

Frontiers in endocrinology

Guo C, Liu G, Zhao D, Mi Y, Zhang C, Li J.
PMID: 30837955
Front Endocrinol (Lausanne). 2019 Feb 19;10:91. doi: 10.3389/fendo.2019.00091. eCollection 2019.

Follicle-stimulating hormone (FSH) and KIT signaling are required for ovarian development. In this study the interactive effect of FSH and stem cell factor (SCF) on folliculogenesis was investigated in the chicken. Correlated changes between the FSH receptor and the...

The role of CMV in glioblastoma and implications for immunotherapeutic strategies.

Oncoimmunology

Rahman M, Dastmalchi F, Karachi A, Mitchell D.
PMID: 30546954
Oncoimmunology. 2018 Oct 16;8(1):e1514921. doi: 10.1080/2162402X.2018.1514921. eCollection 2019.

Controversy surrounds the role of cytomegalovirus (CMV) in glioblastoma (GBM). However, several studies have shown that CMV nucleic acids and proteins are present within GBM tumor tissue. CMV has been implicated in GBM pathogenesis by affecting tumor stem cell...

Assessment of Short-Term Engraftment Potential of Ex Vivo Expanded Hematopoietic Stem Cells Using Normal Fetal Mouse in Utero Transplantation Model.

Cell journal

Zarrabi M, Afzal E, Asghari MH, Ebrahimi M.
PMID: 31210431
Cell J. 2019 Oct;21(3):259-267. doi: 10.22074/cellj.2019.6006. Epub 2019 Jun 15.

MATERIALS AND METHODS: In this experimental study, briefly, isolated hUCB-MNCs were cultured in common expansion medium containing stem cell factor, Flt3 ligand and thrombopoietin. The unexpanded and expanded cells were transplanted to the fetal mice on gestational days of...

Regulation of Mast Cell Proliferation, Maturation and Function by Stem Cell Factor, a Ligand for the c-kit Receptor.

International archives of allergy and immunology

Galli SJ, Tsai M, Wershil BK.
PMID: 34167206
Int Arch Allergy Immunol. 1992;99(2):234-237. doi: 10.1159/000236255. Epub 2009 Sep 02.

Mast cell development in mice is critically regulated by stem cell factor (SCF), a product of fibroblasts and other cell types which is a ligand for the tyrosine kinase receptor protein encoded by the proto-oncogene c-kit. In mice, recombinant...

SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation.

Molecular cancer research : MCR

Adolphe C, Millar A, Kojic M, Barkauskas DS, Sundström A, Swartling FJ, Hediyeh-Zadeh S, Tan CW, Davis MJ, Genovesi LA, Wainwright BJ.
PMID: 34330843
Mol Cancer Res. 2021 Nov;19(11):1831-1839. doi: 10.1158/1541-7786.MCR-21-0117. Epub 2021 Jul 30.

Medulloblastoma is the most common malignant pediatric brain tumor and there is an urgent need for molecularly targeted and subgroup-specific therapies. The stem cell factor SOX9, has been proposed as a potential therapeutic target for the treatment of Sonic...

Signaling changes in the stem cell factor-AKT-S6 pathway in diagnostic AML samples are associated with disease relapse.

Blood cancer journal

Kornblau SM, Covey T, Putta S, Cohen A, Woronicz J, Fantl WJ, Gayko U, Cesano A.
PMID: 22829109
Blood Cancer J. 2011 Feb;1(2):e3. doi: 10.1038/bcj.2010.2. Epub 2011 Feb 11.

No abstract available.

Dermal Mesenchymal Stem Cells from Psoriatic Lesions Stimulate HaCaT Cell Proliferation, Differentiation, and Migration via Activating the PI3K/AKT Signaling Pathway.

Dermatology (Basel, Switzerland)

Liang N, Chang W, Peng A, Cao Y, Li J, Wang Y, Jiao J, Zhang K.
PMID: 34175855
Dermatology. 2021 Jun 25;1-9. doi: 10.1159/000515767. Epub 2021 Jun 25.

BACKGROUND: Psoriasis is a chronic inflammatory skin disease characterized by excessive proliferation and abnormal differentiation of keratinocytes. Dermal mesenchymal stem cells (DMSCs) are not only involved in the regeneration of skin tissue, but also can regulate skin microenvironment by...

3D Multicellular Stem-Like Human Breast Tumor Spheroids Enhance Tumorigenicity of Orthotopic Xenografts in Athymic Nude Rat Model.

Cancers

Mokhtari RB, Qorri B, Sambi M, Baluch N, Kumar S, Das B, Szewczuk MR, Yeger H, Cheng HM.
PMID: 34205080
Cancers (Basel). 2021 Jun 03;13(11). doi: 10.3390/cancers13112784.

Therapeutic targeting of stem cells needs to be strategically developed to control tumor growth and prevent metastatic burden successfully. Breast cancer presents a unique clinical problem because of the variety of cellular subtypes present, including cancer stem cells (CSCs)....

Showing 25 to 36 of 301 entries