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Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting.

Core evidence

Chrisp P.
PMID: 21221195
Core Evid. 2007 Mar 31;2(1):15-30.

INTRODUCTION: Chemotherapy-induced nausea and vomiting (CINV) represents a significant burden on patients and healthcare systems. Despite the introduction of serotonin antagonists, many patients still experience CINV, particularly delayed symptoms occurring more than 24 hours after chemotherapy. Aprepitant is a...

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Chrisp P. Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting. Core Evid. 2007;2(1):15-30
Chrisp, P. (2007). Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting. Core evidence, 2(1), 15-30.
Chrisp, Paul. "Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting." Core evidence vol. 2,1 (2007): 15-30.
Chrisp P. Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting. Core Evid. 2007 Mar 31;2(1):15-30. PMID: 21221195; PMCID: PMC3012554.
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Palonosetron exhibits higher total control rate compared to first-generation serotonin antagonists and improves appetite in delayed-phase chemotherapy-induced nausea and vomiting.

Molecular and clinical oncology

Ueda H, Shimono C, Nishimura T, Shimamoto M, Yamaue H.
PMID: 24772303
Mol Clin Oncol. 2014 May;2(3):375-379. doi: 10.3892/mco.2014.263. Epub 2014 Feb 20.

In order to ensure the continuity of chemotherapy, it is crucial to provide appropriate supportive care to prevent chemotherapy-induced nausea and vomiting (CINV). The frequency of CINV is greatly affected by the type and combination of chemotherapy employed, which...

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Ueda H, Shimono C, Nishimura T, et al. Palonosetron exhibits higher total control rate compared to first-generation serotonin antagonists and improves appetite in delayed-phase chemotherapy-induced nausea and vomiting. Mol Clin Oncol. 2014;2(3):375-379doi: 10.3892/mco.2014.263.
Ueda, H., Shimono, C., Nishimura, T., Shimamoto, M., & Yamaue, H. (2014). Palonosetron exhibits higher total control rate compared to first-generation serotonin antagonists and improves appetite in delayed-phase chemotherapy-induced nausea and vomiting. Molecular and clinical oncology, 2(3), 375-379. https://doi.org/10.3892/mco.2014.263
Ueda, Hiroki, et al. "Palonosetron exhibits higher total control rate compared to first-generation serotonin antagonists and improves appetite in delayed-phase chemotherapy-induced nausea and vomiting." Molecular and clinical oncology vol. 2,3 (2014): 375-379. doi: https://doi.org/10.3892/mco.2014.263
Ueda H, Shimono C, Nishimura T, Shimamoto M, Yamaue H. Palonosetron exhibits higher total control rate compared to first-generation serotonin antagonists and improves appetite in delayed-phase chemotherapy-induced nausea and vomiting. Mol Clin Oncol. 2014 May;2(3):375-379. doi: 10.3892/mco.2014.263. Epub 2014 Feb 20. PMID: 24772303; PMCID: PMC3999141.
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Antiemetic drugs: what to prescribe and when.

Australian prescriber

Athavale A, Athavale T, Roberts DM.
PMID: 32346211
Aust Prescr. 2020 Apr;43(2):49-56. doi: 10.18773/austprescr.2020.011. Epub 2020 Apr 01.

Nausea and vomiting are common symptoms with many possible causes, including the adverse effects of drugs. If a drug is indicated, the cause guides the choice of antiemetic drug The main antiemetic classes include antagonists of the serotonin, dopamine,...

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Athavale A, Athavale T, Roberts DM. Antiemetic drugs: what to prescribe and when. Aust Prescr. 2020;43(2):49-56doi: 10.18773/austprescr.2020.011.
Athavale, A., Athavale, T., & Roberts, D. M. (2020). Antiemetic drugs: what to prescribe and when. Australian prescriber, 43(2), 49-56. https://doi.org/10.18773/austprescr.2020.011
Athavale, Akshay, et al. "Antiemetic drugs: what to prescribe and when." Australian prescriber vol. 43,2 (2020): 49-56. doi: https://doi.org/10.18773/austprescr.2020.011
Athavale A, Athavale T, Roberts DM. Antiemetic drugs: what to prescribe and when. Aust Prescr. 2020 Apr;43(2):49-56. doi: 10.18773/austprescr.2020.011. Epub 2020 Apr 01. PMID: 32346211; PMCID: PMC7186277.
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Other Preventive Anti-Migraine Treatments: ACE Inhibitors, ARBs, Calcium Channel Blockers, Serotonin Antagonists, and NMDA Receptor Antagonists.

Current treatment options in neurology

Rau JC, Dodick DW.
PMID: 30880363
Curr Treat Options Neurol. 2019 Mar 18;21(4):17. doi: 10.1007/s11940-019-0559-0.

PURPOSE OF REVIEW: Migraine causes more years of life lived with disability than almost any other condition in the world and can significantly impact the lives of individuals with migraine, their families, and society. The use of medication for...

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Rau JC, Dodick DW. Other Preventive Anti-Migraine Treatments: ACE Inhibitors, ARBs, Calcium Channel Blockers, Serotonin Antagonists, and NMDA Receptor Antagonists. Curr Treat Options Neurol. 2019;21(4):17doi: 10.1007/s11940-019-0559-0.
Rau, J. C., & Dodick, D. W. (2019). Other Preventive Anti-Migraine Treatments: ACE Inhibitors, ARBs, Calcium Channel Blockers, Serotonin Antagonists, and NMDA Receptor Antagonists. Current treatment options in neurology, 21(4), 17. https://doi.org/10.1007/s11940-019-0559-0
Rau, Jill C, and Dodick, David W. "Other Preventive Anti-Migraine Treatments: ACE Inhibitors, ARBs, Calcium Channel Blockers, Serotonin Antagonists, and NMDA Receptor Antagonists." Current treatment options in neurology vol. 21,4 (2019): 17. doi: https://doi.org/10.1007/s11940-019-0559-0
Rau JC, Dodick DW. Other Preventive Anti-Migraine Treatments: ACE Inhibitors, ARBs, Calcium Channel Blockers, Serotonin Antagonists, and NMDA Receptor Antagonists. Curr Treat Options Neurol. 2019 Mar 18;21(4):17. doi: 10.1007/s11940-019-0559-0. PMID: 30880363.
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Obstructive sleep apnea in a Chihuahua successfully managed with ondansetron.

Clinical case reports

Kopke MA, Wightman P, Ruaux CG.
PMID: 31110706
Clin Case Rep. 2019 Mar 22;7(5):872-876. doi: 10.1002/ccr3.2110. eCollection 2019 May.

While the persistence of clinical signs related to brachycephalic obstructive airway syndrome, particularly sleep-disordered breathing patterns following appropriate surgical management is likely to be relatively rare, this potential sequela needs to be considered, along with being aware of possible...

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Kopke MA, Wightman P, Ruaux CG. Obstructive sleep apnea in a Chihuahua successfully managed with ondansetron. Clin Case Rep. 2019;7(5):872-876doi: 10.1002/ccr3.2110.
Kopke, M. A., Wightman, P., & Ruaux, C. G. (2019). Obstructive sleep apnea in a Chihuahua successfully managed with ondansetron. Clinical case reports, 7(5), 872-876. https://doi.org/10.1002/ccr3.2110
Kopke, Matthew A, et al. "Obstructive sleep apnea in a Chihuahua successfully managed with ondansetron." Clinical case reports vol. 7,5 (2019): 872-876. doi: https://doi.org/10.1002/ccr3.2110
Kopke MA, Wightman P, Ruaux CG. Obstructive sleep apnea in a Chihuahua successfully managed with ondansetron. Clin Case Rep. 2019 Mar 22;7(5):872-876. doi: 10.1002/ccr3.2110. eCollection 2019 May. PMID: 31110706; PMCID: PMC6510004.
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Review Article: Current and future treatment approaches for IBS with diarrhoea (IBS-D) and IBS mixed pattern (IBS-M).

Alimentary pharmacology & therapeutics

Nee J, Lembo A.
PMID: 34927757
Aliment Pharmacol Ther. 2021 Dec;54:S63-S74. doi: 10.1111/apt.16625.

BACKGROUND: Irritable bowel syndrome-diarrhoea (IBS-D) and IBS-mixed stool pattern (IBS-M) are disorders of gut-brain interaction characterised by abdominal pain associated with diarrhoea or both diarrhoea and constipation respectively. The pathophysiology of IBS-D/M is multifactorial and not completely understood; thus,...

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Nee J, Lembo A. Review Article: Current and future treatment approaches for IBS with diarrhoea (IBS-D) and IBS mixed pattern (IBS-M). Aliment Pharmacol Ther. 2021;54:S63-S74doi: 10.1111/apt.16625.
Nee, J., & Lembo, A. (2021). Review Article: Current and future treatment approaches for IBS with diarrhoea (IBS-D) and IBS mixed pattern (IBS-M). Alimentary pharmacology & therapeutics, 54S63-S74. https://doi.org/10.1111/apt.16625
Nee, Judy, and Lembo, Anthony. "Review Article: Current and future treatment approaches for IBS with diarrhoea (IBS-D) and IBS mixed pattern (IBS-M)." Alimentary pharmacology & therapeutics vol. 54 (2021): S63-S74. doi: https://doi.org/10.1111/apt.16625
Nee J, Lembo A. Review Article: Current and future treatment approaches for IBS with diarrhoea (IBS-D) and IBS mixed pattern (IBS-M). Aliment Pharmacol Ther. 2021 Dec;54:S63-S74. doi: 10.1111/apt.16625. PMID: 34927757.
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Roles of dopamine and serotonin in larval attachment of the barnacle, Balanus amphitrite.

The Journal of experimental zoology

Yamamoto H, Shimizu K, Tachibana A, Fusetani N.
PMID: 10620768
J Exp Zool. 1999 Dec 01;284(7):746-758. doi: 10.1002/(sici)1097-010x(19991201)284:7<746::aid-jez4>3.0.co;2-j.

In order to clarify the roles of neurotransmitters including serotonin and dopamine in larval settlement (attachment) and metamorphosis of the barnacle Balanus amphitrite, the effects of lisuride, which acts as both a serotonin agonist/antagonist and a dopamine agonist, were...

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Yamamoto H, Shimizu K, Tachibana A, et al. Roles of dopamine and serotonin in larval attachment of the barnacle, Balanus amphitrite. J Exp Zool. 1999;284(7):746-758doi: 10.1002/(sici)1097-010x(19991201)284:7<746::aid-jez4>3.0.co;2-j.
Yamamoto, H., Shimizu, K., Tachibana, A., & Fusetani, N. (1999). Roles of dopamine and serotonin in larval attachment of the barnacle, Balanus amphitrite. The Journal of experimental zoology, 284(7), 746-758. https://doi.org/10.1002/(sici)1097-010x(19991201)284:7<746::aid-jez4>3.0.co;2-j
Yamamoto, et al. "Roles of dopamine and serotonin in larval attachment of the barnacle, Balanus amphitrite." The Journal of experimental zoology vol. 284,7 (1999): 746-758. doi: https://doi.org/10.1002/(sici)1097-010x(19991201)284:7<746::aid-jez4>3.0.co;2-j
Yamamoto H, Shimizu K, Tachibana A, Fusetani N. Roles of dopamine and serotonin in larval attachment of the barnacle, Balanus amphitrite. J Exp Zool. 1999 Dec 01;284(7):746-758. doi: 10.1002/(sici)1097-010x(19991201)284:7<746::aid-jez4>3.0.co;2-j. PMID: 10620768.
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Pharmacotherapy of chronic alcoholism: a review.

Drugs of today (Barcelona, Spain : 1998)

Singh AN, Srivastava S, Jainar AK.
PMID: 12973406
Drugs Today (Barc). 1999 Jan;35(1):27-33. doi: 10.1358/dot.1999.35.1.522944.

Although alcohol has been recognized as an agent of abuse since the 17th century, the disease model was accepted only in the last century. Alcoholism is defined as a chronic and progressive disease characterized by loss of control over...

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Singh AN, Srivastava S, Jainar AK. Pharmacotherapy of chronic alcoholism: a review. Drugs Today (Barc). 1999;35(1):27-33doi: 10.1358/dot.1999.35.1.522944.
Singh, A. N., Srivastava, S., & Jainar, A. K. (1999). Pharmacotherapy of chronic alcoholism: a review. Drugs of today (Barcelona, Spain : 1998), 35(1), 27-33. https://doi.org/10.1358/dot.1999.35.1.522944
Singh, A N, et al. "Pharmacotherapy of chronic alcoholism: a review." Drugs of today (Barcelona, Spain : 1998) vol. 35,1 (1999): 27-33. doi: https://doi.org/10.1358/dot.1999.35.1.522944
Singh AN, Srivastava S, Jainar AK. Pharmacotherapy of chronic alcoholism: a review. Drugs Today (Barc). 1999 Jan;35(1):27-33. doi: 10.1358/dot.1999.35.1.522944. PMID: 12973406.
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Case histories in drug discovery and design.

Drug news & perspectives

[No authors listed]
PMID: 15616642
Drug News Perspect. 1998 Feb;11(1):52-7.

Seven highly informative accounts of drug discovery and design were delivered by members of an international panel of speakers. The evolution of a new drug treatment for schizophrenia commenced with the observation that chlorpromazine possessed "neuroleptic" activity and progressed...

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Case histories in drug discovery and design. Drug News Perspect. 1998;11(1):52-7
(1998). Case histories in drug discovery and design. Drug news & perspectives, 11(1), 52-7.
"Case histories in drug discovery and design." Drug news & perspectives vol. 11,1 (1998): 52-7.
Case histories in drug discovery and design. Drug News Perspect. 1998 Feb;11(1):52-7. PMID: 15616642.
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A Randomized Double-Blind, Double-Dummy, Multicenter Trial of Azasetron versus Ondansetron to Evaluate Efficacy and Safety in the Prevention of Delayed Nausea and Vomiting Induced by Chemotherapy.

Cancer research and treatment

Lee HY, Kim HK, Lee KH, Kim BS, Song HS, Yang SH, Kim JH, Kim YH, Kim JG, Kim SW, Kim DW, Kim SY, Park HS.
PMID: 24520219
Cancer Res Treat. 2014 Jan;46(1):19-26. doi: 10.4143/crt.2014.46.1.19. Epub 2014 Jan 15.

PURPOSE: This study was conducted to evaluate the efficacy and safety of azasetron compared to ondansetron in the prevention of delayed chemotherapy-induced nausea and vomiting.MATERIALS AND METHODS: This study was a multi-center, prospective, randomized, double-dummy, double-blind and parallel-group trial...

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Lee HY, Kim HK, Lee KH, et al. A Randomized Double-Blind, Double-Dummy, Multicenter Trial of Azasetron versus Ondansetron to Evaluate Efficacy and Safety in the Prevention of Delayed Nausea and Vomiting Induced by Chemotherapy. Cancer Res Treat. 2014;46(1):19-26doi: 10.4143/crt.2014.46.1.19.
Lee, H. Y., Kim, H. K., Lee, K. H., Kim, B. S., Song, H. S., Yang, S. H., Kim, J. H., Kim, Y. H., Kim, J. G., Kim, S. W., Kim, D. W., Kim, S. Y., & Park, H. S. (2014). A Randomized Double-Blind, Double-Dummy, Multicenter Trial of Azasetron versus Ondansetron to Evaluate Efficacy and Safety in the Prevention of Delayed Nausea and Vomiting Induced by Chemotherapy. Cancer research and treatment, 46(1), 19-26. https://doi.org/10.4143/crt.2014.46.1.19
Lee, Hee Yeon, et al. "A Randomized Double-Blind, Double-Dummy, Multicenter Trial of Azasetron versus Ondansetron to Evaluate Efficacy and Safety in the Prevention of Delayed Nausea and Vomiting Induced by Chemotherapy." Cancer research and treatment vol. 46,1 (2014): 19-26. doi: https://doi.org/10.4143/crt.2014.46.1.19
Lee HY, Kim HK, Lee KH, Kim BS, Song HS, Yang SH, Kim JH, Kim YH, Kim JG, Kim SW, Kim DW, Kim SY, Park HS. A Randomized Double-Blind, Double-Dummy, Multicenter Trial of Azasetron versus Ondansetron to Evaluate Efficacy and Safety in the Prevention of Delayed Nausea and Vomiting Induced by Chemotherapy. Cancer Res Treat. 2014 Jan;46(1):19-26. doi: 10.4143/crt.2014.46.1.19. Epub 2014 Jan 15. PMID: 24520219; PMCID: PMC3918522.
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Intravenous palonosetron compared with a combination of ramosetron and dexamethasone in preventing post operative nausea and vomiting in patients undergoing gynaecological surgeries under spinal anaesthesia, a randomised study.

Indian journal of anaesthesia

Narayanappa AB, Gurulingaswamy S, Prabhakaraiah UN, Gurushanth SR, Sapare V, Goud N.
PMID: 28250483
Indian J Anaesth. 2017 Feb;61(2):144-149. doi: 10.4103/0019-5049.199851.

BACKGROUND AND AIMS: Post-operative nausea and vomiting (PONV) is one of the most common complications in patients undergoing gynaecological surgeries under spinal anaesthesia (SA). Palonosetron has the unique property of controlling 'delayed chemotherapy-induced nausea and vomiting' when compared to...

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Narayanappa AB, Gurulingaswamy S, Prabhakaraiah UN, et al. Intravenous palonosetron compared with a combination of ramosetron and dexamethasone in preventing post operative nausea and vomiting in patients undergoing gynaecological surgeries under spinal anaesthesia, a randomised study. Indian J Anaesth. 2017;61(2):144-149doi: 10.4103/0019-5049.199851.
Narayanappa, A. B., Gurulingaswamy, S., Prabhakaraiah, U. N., Gurushanth, S. R., Sapare, V., & Goud, N. (2017). Intravenous palonosetron compared with a combination of ramosetron and dexamethasone in preventing post operative nausea and vomiting in patients undergoing gynaecological surgeries under spinal anaesthesia, a randomised study. Indian journal of anaesthesia, 61(2), 144-149. https://doi.org/10.4103/0019-5049.199851
Narayanappa, Archana B, et al. "Intravenous palonosetron compared with a combination of ramosetron and dexamethasone in preventing post operative nausea and vomiting in patients undergoing gynaecological surgeries under spinal anaesthesia, a randomised study." Indian journal of anaesthesia vol. 61,2 (2017): 144-149. doi: https://doi.org/10.4103/0019-5049.199851
Narayanappa AB, Gurulingaswamy S, Prabhakaraiah UN, Gurushanth SR, Sapare V, Goud N. Intravenous palonosetron compared with a combination of ramosetron and dexamethasone in preventing post operative nausea and vomiting in patients undergoing gynaecological surgeries under spinal anaesthesia, a randomised study. Indian J Anaesth. 2017 Feb;61(2):144-149. doi: 10.4103/0019-5049.199851. PMID: 28250483; PMCID: PMC5330071.
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The role of serotonin in preeclamptic hypertension. A review and case report.

International journal of obstetric anesthesia

Hutter C, Crighton IM, Smith K, Liu DT.
PMID: 15321364
Int J Obstet Anesth. 1996 Apr;5(2):108-14. doi: 10.1016/s0959-289x(96)80009-4.

Generalized arteriolar vasospasm and subsequent damage to vascular endothelium are fundamental to the development of preeclampsia. A possible mechanism underlying this involves increased deportation of trophoblast cells into maternal venous circulation with 5-hydroxytryptamine (serotonin, 5-HT) release as a consequence...

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Hutter C, Crighton IM, Smith K, et al. The role of serotonin in preeclamptic hypertension. A review and case report. Int J Obstet Anesth. 1996;5(2):108-14doi: 10.1016/s0959-289x(96)80009-4.
Hutter, C., Crighton, I. M., Smith, K., & Liu, D. T. (1996). The role of serotonin in preeclamptic hypertension. A review and case report. International journal of obstetric anesthesia, 5(2), 108-14. https://doi.org/10.1016/s0959-289x(96)80009-4
Hutter, C, et al. "The role of serotonin in preeclamptic hypertension. A review and case report." International journal of obstetric anesthesia vol. 5,2 (1996): 108-14. doi: https://doi.org/10.1016/s0959-289x(96)80009-4
Hutter C, Crighton IM, Smith K, Liu DT. The role of serotonin in preeclamptic hypertension. A review and case report. Int J Obstet Anesth. 1996 Apr;5(2):108-14. doi: 10.1016/s0959-289x(96)80009-4. PMID: 15321364.
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Showing 13 to 24 of 24 entries