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Promising Antifungal and Antibacterial Agents Based on 5-Aryl-2,2'-bipyridines and Their Heteroligand Salicylate Metal Complexes: Synthesis, Bioevaluation, Molecular Docking.

ChemMedChem

Burgart Y, Shchegolkov E, Shchur I, Kopchuk D, Gerasimova N, Borisevich S, Evstigneeva N, Zyryanov G, Savchuk M, Ulitko M, Zilberberg N, Kungurov N, Saloutin V, Charushin V, Chupakhin O.
PMID: 34783161
ChemMedChem. 2021 Nov 15; doi: 10.1002/cmdc.202100577. Epub 2021 Nov 15.

A series of new 5-aryl-2,2'-bipyridines and their (polyfluoro)salicylate complexes of Cu(II), Co(II) and Mn(II) were synthesized. Their antimicrobial activity was evaluated in vitro against six strains of Trichophytons, E. floccosum, M. canis, C. ablicans and Gram-negative bacteria N. gonorrhoeae....

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Burgart Y, Shchegolkov E, Shchur I, et al. Promising Antifungal and Antibacterial Agents Based on 5-Aryl-2,2'-bipyridines and Their Heteroligand Salicylate Metal Complexes: Synthesis, Bioevaluation, Molecular Docking. ChemMedChem. 2021;doi: 10.1002/cmdc.202100577.
Burgart, Y., Shchegolkov, E., Shchur, I., Kopchuk, D., Gerasimova, N., Borisevich, S., Evstigneeva, N., Zyryanov, G., Savchuk, M., Ulitko, M., Zilberberg, N., Kungurov, N., Saloutin, V., Charushin, V., & Chupakhin, O. (2021). Promising Antifungal and Antibacterial Agents Based on 5-Aryl-2,2'-bipyridines and Their Heteroligand Salicylate Metal Complexes: Synthesis, Bioevaluation, Molecular Docking. ChemMedChem, . https://doi.org/10.1002/cmdc.202100577
Burgart, Yanina, et al. "Promising Antifungal and Antibacterial Agents Based on 5-Aryl-2,2'-bipyridines and Their Heteroligand Salicylate Metal Complexes: Synthesis, Bioevaluation, Molecular Docking." ChemMedChem vol. (2021). doi: https://doi.org/10.1002/cmdc.202100577
Burgart Y, Shchegolkov E, Shchur I, Kopchuk D, Gerasimova N, Borisevich S, Evstigneeva N, Zyryanov G, Savchuk M, Ulitko M, Zilberberg N, Kungurov N, Saloutin V, Charushin V, Chupakhin O. Promising Antifungal and Antibacterial Agents Based on 5-Aryl-2,2'-bipyridines and Their Heteroligand Salicylate Metal Complexes: Synthesis, Bioevaluation, Molecular Docking. ChemMedChem. 2021 Nov 15; doi: 10.1002/cmdc.202100577. Epub 2021 Nov 15. PMID: 34783161.
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Quantum Mechanics/Molecular Mechanics Studies on the Photophysical Mechanism of Methyl Salicylate.

The journal of physical chemistry. A

Chang XP, Zhang TS, Fang YG, Cui G.
PMID: 33645980
J Phys Chem A. 2021 Mar 11;125(9):1880-1891. doi: 10.1021/acs.jpca.0c10589. Epub 2021 Mar 01.

Methyl salicylate (MS) as a subunit of larger salicylates found in commercial sunscreens has been shown to exhibit keto-enol tautomerization and dual fluorescence emission via excited-state intramolecular proton transfer (ESIPT) after the absorption of ultraviolet (UV) radiation. However, its...

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Chang XP, Zhang TS, Fang YG, et al. Quantum Mechanics/Molecular Mechanics Studies on the Photophysical Mechanism of Methyl Salicylate. J Phys Chem A. 2021;125(9):1880-1891doi: 10.1021/acs.jpca.0c10589.
Chang, X. P., Zhang, T. S., Fang, Y. G., & Cui, G. (2021). Quantum Mechanics/Molecular Mechanics Studies on the Photophysical Mechanism of Methyl Salicylate. The journal of physical chemistry. A, 125(9), 1880-1891. https://doi.org/10.1021/acs.jpca.0c10589
Chang, Xue-Ping, et al. "Quantum Mechanics/Molecular Mechanics Studies on the Photophysical Mechanism of Methyl Salicylate." The journal of physical chemistry. A vol. 125,9 (2021): 1880-1891. doi: https://doi.org/10.1021/acs.jpca.0c10589
Chang XP, Zhang TS, Fang YG, Cui G. Quantum Mechanics/Molecular Mechanics Studies on the Photophysical Mechanism of Methyl Salicylate. J Phys Chem A. 2021 Mar 11;125(9):1880-1891. doi: 10.1021/acs.jpca.0c10589. Epub 2021 Mar 01. PMID: 33645980.
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Protective Effect of Curcumin against Sodium Salicylate-Induced Oxidative Kidney Damage, Nuclear Factor-Kappa Dysregulation, and Apoptotic Consequences in Rats.

Antioxidants (Basel, Switzerland)

Abd-Elhakim YM, Moselhy AAA, Aldhahrani A, Beheiry RR, Mohamed WAM, Soliman MM, Saffaf BA, M El Deib M.
PMID: 34064189
Antioxidants (Basel). 2021 May 21;10(6). doi: 10.3390/antiox10060826.

This study examined the effect of sodium salicylates (SS), alone and in combination with curcumin (CUR), on kidney function and architecture in rats. Five rat groups were given 1 mL physiological saline/rat orally, 1 mL olive oil/rat orally, 50...

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Abd-Elhakim YM, Moselhy AAA, Aldhahrani A, et al. Protective Effect of Curcumin against Sodium Salicylate-Induced Oxidative Kidney Damage, Nuclear Factor-Kappa Dysregulation, and Apoptotic Consequences in Rats. Antioxidants (Basel). 2021;10(6)doi: 10.3390/antiox10060826.
Abd-Elhakim, Y. M., Moselhy, A. A. A., Aldhahrani, A., Beheiry, R. R., Mohamed, W. A. M., Soliman, M. M., Saffaf, B. A., & M El Deib, M. (2021). Protective Effect of Curcumin against Sodium Salicylate-Induced Oxidative Kidney Damage, Nuclear Factor-Kappa Dysregulation, and Apoptotic Consequences in Rats. Antioxidants (Basel, Switzerland), 10(6), . https://doi.org/10.3390/antiox10060826
Abd-Elhakim, Yasmina M, et al. "Protective Effect of Curcumin against Sodium Salicylate-Induced Oxidative Kidney Damage, Nuclear Factor-Kappa Dysregulation, and Apoptotic Consequences in Rats." Antioxidants (Basel, Switzerland) vol. 10,6 (2021). doi: https://doi.org/10.3390/antiox10060826
Abd-Elhakim YM, Moselhy AAA, Aldhahrani A, Beheiry RR, Mohamed WAM, Soliman MM, Saffaf BA, M El Deib M. Protective Effect of Curcumin against Sodium Salicylate-Induced Oxidative Kidney Damage, Nuclear Factor-Kappa Dysregulation, and Apoptotic Consequences in Rats. Antioxidants (Basel). 2021 May 21;10(6). doi: 10.3390/antiox10060826. PMID: 34064189; PMCID: PMC8224369.
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Topical delivery of salicylates.

Drug delivery and translational research

Yeoh SC, Goh CF, Naylor JM, Dennis S.
PMID: 33907986
Drug Deliv Transl Res. 2021 Apr 28; doi: 10.1007/s13346-021-00988-5. Epub 2021 Apr 28.

Salicylates have a long history of use for pain relief. Salicylic acid and methyl salicylate are among the widely used topical salicylates namely for keratolytic and anti-inflammatory actions, respectively. The current review summarises both passive and active strategies, including...

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Yeoh SC, Goh CF, Naylor JM, et al. Topical delivery of salicylates. Drug Deliv Transl Res. 2021;doi: 10.1007/s13346-021-00988-5.
Yeoh, S. C., Goh, C. F., Naylor, J. M., & Dennis, S. (2021). Topical delivery of salicylates. Drug delivery and translational research, . https://doi.org/10.1007/s13346-021-00988-5
Yeoh, Soo Chin, et al. "Topical delivery of salicylates." Drug delivery and translational research vol. (2021). doi: https://doi.org/10.1007/s13346-021-00988-5
Yeoh SC, Goh CF, Naylor JM, Dennis S. Topical delivery of salicylates. Drug Deliv Transl Res. 2021 Apr 28; doi: 10.1007/s13346-021-00988-5. Epub 2021 Apr 28. PMID: 33907986.
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Time Trends of Crohn's Disease in Catalonia from 2011 to 2017. Increasing Use of Biologics Correlates with a Reduced Need for Surgery.

Journal of clinical medicine

Brunet E, Vela E, Melcarne L, Clèries M, Pontes C, Llovet LP, García-Iglesias P, Gallach M, Villòria A, Vergara M, Calvet X.
PMID: 32911630
J Clin Med. 2020 Sep 08;9(9). doi: 10.3390/jcm9092896.

BACKGROUND AND AIMS: Data from clinical trials suggest that biological drugs may improve the outcomes in Crohn's disease (CD) by reducing the need for surgery or hospitalization. The aim of this study is to evaluate the time-trends of the...

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Brunet E, Vela E, Melcarne L, et al. Time Trends of Crohn's Disease in Catalonia from 2011 to 2017. Increasing Use of Biologics Correlates with a Reduced Need for Surgery. J Clin Med. 2020;9(9)doi: 10.3390/jcm9092896.
Brunet, E., Vela, E., Melcarne, L., Clèries, M., Pontes, C., Llovet, L. P., García-Iglesias, P., Gallach, M., Villòria, A., Vergara, M., & Calvet, X. (2020). Time Trends of Crohn's Disease in Catalonia from 2011 to 2017. Increasing Use of Biologics Correlates with a Reduced Need for Surgery. Journal of clinical medicine, 9(9), . https://doi.org/10.3390/jcm9092896
Brunet, Eduard, et al. "Time Trends of Crohn's Disease in Catalonia from 2011 to 2017. Increasing Use of Biologics Correlates with a Reduced Need for Surgery." Journal of clinical medicine vol. 9,9 (2020). doi: https://doi.org/10.3390/jcm9092896
Brunet E, Vela E, Melcarne L, Clèries M, Pontes C, Llovet LP, García-Iglesias P, Gallach M, Villòria A, Vergara M, Calvet X. Time Trends of Crohn's Disease in Catalonia from 2011 to 2017. Increasing Use of Biologics Correlates with a Reduced Need for Surgery. J Clin Med. 2020 Sep 08;9(9). doi: 10.3390/jcm9092896. PMID: 32911630; PMCID: PMC7563515.
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Honorary Professor Garry Graham.

Inflammopharmacology

Day RO, Williams KM, Scott KF.
PMID: 34533655
Inflammopharmacology. 2021 Oct;29(5):1255-1259. doi: 10.1007/s10787-021-00872-1. Epub 2021 Sep 17.

An appreciation of the contribution of Professor Gary Graham to anti-inflammatory and antirheumatic pharmacology and clinical pharmacology.

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Day RO, Williams KM, Scott KF. Honorary Professor Garry Graham. Inflammopharmacology. 2021;29(5):1255-1259doi: 10.1007/s10787-021-00872-1.
Day, R. O., Williams, K. M., & Scott, K. F. (2021). Honorary Professor Garry Graham. Inflammopharmacology, 29(5), 1255-1259. https://doi.org/10.1007/s10787-021-00872-1
Day, Richard O, et al. "Honorary Professor Garry Graham." Inflammopharmacology vol. 29,5 (2021): 1255-1259. doi: https://doi.org/10.1007/s10787-021-00872-1
Day RO, Williams KM, Scott KF. Honorary Professor Garry Graham. Inflammopharmacology. 2021 Oct;29(5):1255-1259. doi: 10.1007/s10787-021-00872-1. Epub 2021 Sep 17. PMID: 34533655.
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P049 Investigation of Liver Diseases by Ultrasound in Patients With Inflammatory Bowel Disease.

The American journal of gastroenterology

Shintaku D, Lopes M, de Oliveira AC, Beraldo R, Godoi G, Castelhano N, Pereira J, Vulcano D, de Oliveira EC, Herrerias G, Saad-Hossne R, Baima J, Barbosa W, Silva G, Sassaki L.
PMID: 35006176
Am J Gastroenterol. 2021 Dec 01;116:S12-S13. doi: 10.14309/01.ajg.0000798796.64423.34.

BACKGROUND: Inflammatory Bowel Disease (IBD), which can be divided into Crohn's Disease (CD) and Ulcerative Colitis (UC), is an immune mediated disease featured by gastrointestinal tract involvement. Hepatic disease, such as non-alcoholic fatty liver disease (NAFLD), cirrhosis, cholelithiasis, hepatic...

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Shintaku D, Lopes M, de Oliveira AC, et al. P049 Investigation of Liver Diseases by Ultrasound in Patients With Inflammatory Bowel Disease. Am J Gastroenterol. 2021;116:S12-S13doi: 10.14309/01.ajg.0000798796.64423.34.
Shintaku, D., Lopes, M., de Oliveira, A. C., Beraldo, R., Godoi, G., Castelhano, N., Pereira, J., Vulcano, D., de Oliveira, E. C., Herrerias, G., Saad-Hossne, R., Baima, J., Barbosa, W., Silva, G., & Sassaki, L. (2021). P049 Investigation of Liver Diseases by Ultrasound in Patients With Inflammatory Bowel Disease. The American journal of gastroenterology, 116S12-S13. https://doi.org/10.14309/01.ajg.0000798796.64423.34
Shintaku, Daniel, et al. "P049 Investigation of Liver Diseases by Ultrasound in Patients With Inflammatory Bowel Disease." The American journal of gastroenterology vol. 116 (2021): S12-S13. doi: https://doi.org/10.14309/01.ajg.0000798796.64423.34
Shintaku D, Lopes M, de Oliveira AC, Beraldo R, Godoi G, Castelhano N, Pereira J, Vulcano D, de Oliveira EC, Herrerias G, Saad-Hossne R, Baima J, Barbosa W, Silva G, Sassaki L. P049 Investigation of Liver Diseases by Ultrasound in Patients With Inflammatory Bowel Disease. Am J Gastroenterol. 2021 Dec 01;116:S12-S13. doi: 10.14309/01.ajg.0000798796.64423.34. PMID: 35006176.
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Clinical and Demographic Profile of Inflammatory Bowel Disease Patients in a Reference Center of São Paulo, Brazil.

Clinical and experimental gastroenterology

Gomes TNF, de Azevedo FS, Argollo M, Miszputen SJ, Ambrogini O.
PMID: 33762838
Clin Exp Gastroenterol. 2021 Mar 17;14:91-102. doi: 10.2147/CEG.S288688. eCollection 2021.

BACKGROUND: Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the gastrointestinal tract with an increasing incidence in developing countries.PURPOSE: To report clinical and demographic data of CD and UC at a referral center for inflammatory...

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Gomes TNF, de Azevedo FS, Argollo M, et al. Clinical and Demographic Profile of Inflammatory Bowel Disease Patients in a Reference Center of São Paulo, Brazil. Clin Exp Gastroenterol. 2021;14:91-102doi: 10.2147/CEG.S288688.
Gomes, T. N. F., de Azevedo, F. S., Argollo, M., Miszputen, S. J., & Ambrogini, O. (2021). Clinical and Demographic Profile of Inflammatory Bowel Disease Patients in a Reference Center of São Paulo, Brazil. Clinical and experimental gastroenterology, 1491-102. https://doi.org/10.2147/CEG.S288688
Gomes, Tarcia Nogueira Ferreira, et al. "Clinical and Demographic Profile of Inflammatory Bowel Disease Patients in a Reference Center of São Paulo, Brazil." Clinical and experimental gastroenterology vol. 14 (2021): 91-102. doi: https://doi.org/10.2147/CEG.S288688
Gomes TNF, de Azevedo FS, Argollo M, Miszputen SJ, Ambrogini O. Clinical and Demographic Profile of Inflammatory Bowel Disease Patients in a Reference Center of São Paulo, Brazil. Clin Exp Gastroenterol. 2021 Mar 17;14:91-102. doi: 10.2147/CEG.S288688. eCollection 2021. PMID: 33762838; PMCID: PMC7982433.
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Complexity of coordinative bonding in thallium(I) anthranilates and salicylates.

Journal of the American Chemical Society

Wiesbrock F, Schmidbaur H.
PMID: 12643725
J Am Chem Soc. 2003 Mar 26;125(12):3622-30. doi: 10.1021/ja0287783.

An inventory of the structural chemistry of thallium(I) shows many unexpected, almost random coordination numbers and coordination geometries that appear erratic and inconsistent. This nonstandard behavior is often ascribed to the specific lone-pair characteristics originating from relativistic effects. To...

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Wiesbrock F, Schmidbaur H. Complexity of coordinative bonding in thallium(I) anthranilates and salicylates. J Am Chem Soc. 2003;125(12):3622-30doi: 10.1021/ja0287783.
Wiesbrock, F., & Schmidbaur, H. (2003). Complexity of coordinative bonding in thallium(I) anthranilates and salicylates. Journal of the American Chemical Society, 125(12), 3622-30. https://doi.org/10.1021/ja0287783
Wiesbrock, Frank, and Schmidbaur, Hubert. "Complexity of coordinative bonding in thallium(I) anthranilates and salicylates." Journal of the American Chemical Society vol. 125,12 (2003): 3622-30. doi: https://doi.org/10.1021/ja0287783
Wiesbrock F, Schmidbaur H. Complexity of coordinative bonding in thallium(I) anthranilates and salicylates. J Am Chem Soc. 2003 Mar 26;125(12):3622-30. doi: 10.1021/ja0287783. PMID: 12643725.
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Salicylates and Congenital Malformations.

British medical journal

[No authors listed]
PMID: 20789640
Br Med J. 1963 Feb 09;1(5327):352.

No abstract available.

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Salicylates and Congenital Malformations. Br Med J. 1963;1(5327):352
(1963). Salicylates and Congenital Malformations. British medical journal, 1(5327), 352.
"Salicylates and Congenital Malformations." British medical journal vol. 1,5327 (1963): 352.
Salicylates and Congenital Malformations. Br Med J. 1963 Feb 09;1(5327):352. PMID: 20789640; PMCID: PMC2123828.
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Hemorrhagic shock as a sequela of splenic rupture in a patient with infectious mononucleosis: focus on the potential role of salicylates.

Case reports in medicine

Bouliaris K, Karangelis D, Daskalopoulos M, Spanos K, Fanariotis M, Giaglaras A.
PMID: 22431933
Case Rep Med. 2012;2012:497820. doi: 10.1155/2012/497820. Epub 2012 Feb 06.

Despite the fact that the vast majority of splenic ruptures are traumatic, infectious mononucleosis has been incriminated as a major predisposing factor that affects the integrity of the spleen, thus causing atraumatic ruptures and life-threatening hemorrhages. Herein we present...

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Bouliaris K, Karangelis D, Daskalopoulos M, et al. Hemorrhagic shock as a sequela of splenic rupture in a patient with infectious mononucleosis: focus on the potential role of salicylates. Case Rep Med. 2012;2012:497820doi: 10.1155/2012/497820.
Bouliaris, K., Karangelis, D., Daskalopoulos, M., Spanos, K., Fanariotis, M., & Giaglaras, A. (2012). Hemorrhagic shock as a sequela of splenic rupture in a patient with infectious mononucleosis: focus on the potential role of salicylates. Case reports in medicine, 2012497820. https://doi.org/10.1155/2012/497820
Bouliaris, Konstantinos, et al. "Hemorrhagic shock as a sequela of splenic rupture in a patient with infectious mononucleosis: focus on the potential role of salicylates." Case reports in medicine vol. 2012 (2012): 497820. doi: https://doi.org/10.1155/2012/497820
Bouliaris K, Karangelis D, Daskalopoulos M, Spanos K, Fanariotis M, Giaglaras A. Hemorrhagic shock as a sequela of splenic rupture in a patient with infectious mononucleosis: focus on the potential role of salicylates. Case Rep Med. 2012;2012:497820. doi: 10.1155/2012/497820. Epub 2012 Feb 06. PMID: 22431933; PMCID: PMC3295742.
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Nitric Oxide as a Beneficial Signaling Molecule in .

Frontiers in plant science

Nawrocka J, Gromek A, Małolepsza U.
PMID: 31057564
Front Plant Sci. 2019 Apr 17;10:421. doi: 10.3389/fpls.2019.00421. eCollection 2019.

In the present study,

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Nawrocka J, Gromek A, Małolepsza U. Nitric Oxide as a Beneficial Signaling Molecule in . Front Plant Sci. 2019;10:421doi: 10.3389/fpls.2019.00421.
Nawrocka, J., Gromek, A., & Małolepsza, U. (2019). Nitric Oxide as a Beneficial Signaling Molecule in . Frontiers in plant science, 10421. https://doi.org/10.3389/fpls.2019.00421
Nawrocka, Justyna, et al. "Nitric Oxide as a Beneficial Signaling Molecule in ." Frontiers in plant science vol. 10 (2019): 421. doi: https://doi.org/10.3389/fpls.2019.00421
Nawrocka J, Gromek A, Małolepsza U. Nitric Oxide as a Beneficial Signaling Molecule in . Front Plant Sci. 2019 Apr 17;10:421. doi: 10.3389/fpls.2019.00421. eCollection 2019. PMID: 31057564; PMCID: PMC6478799.
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Showing 25 to 36 of 163 entries