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Showing 73 to 80 of 80 entries
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Putting together and taking apart: assembly and disassembly of the Rad51 nucleoprotein filament in DNA repair and genome stability.

Cell stress

Andriuskevicius T, Kotenko O, Makovets S.
PMID: 31225474
Cell Stress. 2018 Mar 28;2(5):96-112. doi: 10.15698/cst2018.05.134.

Homologous recombination is a key mechanism providing both genome stability and genetic diversity in all living organisms. Recombinases play a central role in this pathway: multiple protein subunits of Rad51 or its orthologues bind single-stranded DNA to form a...

Application of Algebraic Topology to Homologous Recombination of DNA.

iScience

Braslavsky I, Stavans J.
PMID: 30240753
iScience. 2018 Jun 29;4:64-67. doi: 10.1016/j.isci.2018.05.008. Epub 2018 May 17.

Brouwer's fixed point theorem, a fundamental theorem in algebraic topology proved more than a hundred years ago, states that given any continuous map from a closed, simply connected set into itself, there is a point that is mapped unto...

Erratum for the Report "Base triplet stepping by the Rad51/RecA family of recombinases" by J. Y. Lee, T. Terakawa, Z. Qi, J. B. Steinfeld, S. Redding, Y. Kwon, W. A. Gaines, W. Zhao, P. Sung, E. C. Greene.

Science (New York, N.Y.)

[No authors listed]
PMID: 26516287
Science. 2015 Oct 30;350(6260):aad6940. doi: 10.1126/science.aad6940.

No abstract available.

Publisher Correction: A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination.

Nature communications

Zhang J, Fujiwara Y, Yamamoto S, Shibuya H.
PMID: 30804343
Nat Commun. 2019 Feb 25;10(1):986. doi: 10.1038/s41467-019-08995-4.

The original version of this Article contained errors in Figure 5. In panel g, the male and female symbols preceding each genotype were inadvertently converted to 'B' and '≅', respectively. These errors have been corrected in both the PDF...

Network Analysis of RAD51 Proteins in Metazoa and the Evolutionary Relationships With Their Archaeal Homologs.

Frontiers in genetics

Jiang S, Lin T, Xie Q, Wang L.
PMID: 30319685
Front Genet. 2018 Sep 26;9:383. doi: 10.3389/fgene.2018.00383. eCollection 2018.

The RAD51 (DNA repair protein RAD51) recombinases are essential for homologous recombination, DNA repair, and genome stability. Overexpression of RAD51 proteins has been observed in many cancer cells, such as thyroid carcinoma, breast cancer, pancreatic cancer, and others. In...

Robust Cre recombinase activity in the biotrophic smut fungus Ustilago maydis enables efficient conditional null mutants in planta.

Genetics

de la Torre A, Jurca M, Hoffmann K, Schmitz L, Heimel K, Kämper J, Pérez-Martín J.
PMID: 34849846
Genetics. 2021 Sep 17; doi: 10.1093/genetics/iyab152. Epub 2021 Sep 17.

Site-specific recombinases have been used in higher eukaryotes, especially in animals, for a broad range of applications, including chromosomal translocations, large deletions, site-specific integration, and tissue-specific as well as conditional knock-outs. The application of site-specific recombination has also been...

Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression.

Psychoneuroendocrinology

Eliwa H, Brizard B, Le Guisquet AM, Hen R, Belzung C, Surget A.
PMID: 33302237
Psychoneuroendocrinology. 2021 Feb;124:105097. doi: 10.1016/j.psyneuen.2020.105097. Epub 2020 Dec 01.

Major depressive disorder is a common debilitating mental health problem that represents one of the leading causes of disability. Up to date, the therapeutic targets and approaches are still limited. Adult hippocampal neurogenesis (AHN) has been proposed as a...

Dual recombinases-based genetic lineage tracing for stem cell research with enhanced precision.

Science China. Life sciences

Jin H, Liu K, Zhou B.
PMID: 33847909
Sci China Life Sci. 2021 Apr 09; doi: 10.1007/s11427-020-1889-9. Epub 2021 Apr 09.

Stem cell research has become a hot topic in biology, as the understanding of stem cell biology can provide new insights for both regenerative medicine and clinical treatment of diseases. Accurately deciphering the fate of stem cells is the...

Showing 73 to 80 of 80 entries