Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 25 to 36 of 80 entries
Sorted by: Best Match Show Resources per page
Pairing of single mutations yields obligate Cre-type site-specific recombinases.

Nucleic acids research

Hoersten J, Ruiz-Gómez G, Lansing F, Rojo-Romanos T, Schmitt LT, Sonntag J, Pisabarro MT, Buchholz F.
PMID: 34951450
Nucleic Acids Res. 2021 Dec 24; doi: 10.1093/nar/gkab1240. Epub 2021 Dec 24.

Tyrosine site-specific recombinases (SSRs) represent a versatile genome editing tool with considerable therapeutic potential. Recent developments to engineer and evolve SSRs into heterotetramers to improve target site flexibility signified a critical step towards their broad utility in genome editing....

Cite
Hoersten J, Ruiz-Gómez G, Lansing F, et al. Pairing of single mutations yields obligate Cre-type site-specific recombinases. Nucleic Acids Res. 2021;doi: 10.1093/nar/gkab1240.
Hoersten, J., Ruiz-Gómez, G., Lansing, F., Rojo-Romanos, T., Schmitt, L. T., Sonntag, J., Pisabarro, M. T., & Buchholz, F. (2021). Pairing of single mutations yields obligate Cre-type site-specific recombinases. Nucleic acids research, . https://doi.org/10.1093/nar/gkab1240
Hoersten, Jenna, et al. "Pairing of single mutations yields obligate Cre-type site-specific recombinases." Nucleic acids research vol. (2021). doi: https://doi.org/10.1093/nar/gkab1240
Hoersten J, Ruiz-Gómez G, Lansing F, Rojo-Romanos T, Schmitt LT, Sonntag J, Pisabarro MT, Buchholz F. Pairing of single mutations yields obligate Cre-type site-specific recombinases. Nucleic Acids Res. 2021 Dec 24; doi: 10.1093/nar/gkab1240. Epub 2021 Dec 24. PMID: 34951450.
Copy Download .nbib Format: NLM
Correction to Light-Inducible Recombinases for Bacterial Optogenetics.

ACS synthetic biology

Sheets MB, Wong WW, Dunlop MJ.
PMID: 33001633
ACS Synth Biol. 2020 Oct 16;9(10):2857-2859. doi: 10.1021/acssynbio.0c00477. Epub 2020 Oct 01.

No abstract available.

Cite
Sheets MB, Wong WW, Dunlop MJ. Correction to Light-Inducible Recombinases for Bacterial Optogenetics. ACS Synth Biol. 2020;9(10):2857-2859doi: 10.1021/acssynbio.0c00477.
Sheets, M. B., Wong, W. W., & Dunlop, M. J. (2020). Correction to Light-Inducible Recombinases for Bacterial Optogenetics. ACS synthetic biology, 9(10), 2857-2859. https://doi.org/10.1021/acssynbio.0c00477
Sheets, Michael B, et al. "Correction to Light-Inducible Recombinases for Bacterial Optogenetics." ACS synthetic biology vol. 9,10 (2020): 2857-2859. doi: https://doi.org/10.1021/acssynbio.0c00477
Sheets MB, Wong WW, Dunlop MJ. Correction to Light-Inducible Recombinases for Bacterial Optogenetics. ACS Synth Biol. 2020 Oct 16;9(10):2857-2859. doi: 10.1021/acssynbio.0c00477. Epub 2020 Oct 01. PMID: 33001633.
Copy Download .nbib Format: NLM
A toolbox for conditional control of gene expression in apicomplexan parasites.

Molecular microbiology

Briquet S, Gissot M, Silvie O.
PMID: 34564906
Mol Microbiol. 2021 Sep 26; doi: 10.1111/mmi.14821. Epub 2021 Sep 26.

Apicomplexan parasites encompass diverse pathogens for humans and animals, including the causative agents of malaria and toxoplasmosis, Plasmodium spp. and Toxoplasma gondii. Genetic manipulation of these parasites has become central to explore parasite biology, unravel gene function and identify...

Cite
Briquet S, Gissot M, Silvie O. A toolbox for conditional control of gene expression in apicomplexan parasites. Mol Microbiol. 2021;doi: 10.1111/mmi.14821.
Briquet, S., Gissot, M., & Silvie, O. (2021). A toolbox for conditional control of gene expression in apicomplexan parasites. Molecular microbiology, . https://doi.org/10.1111/mmi.14821
Briquet, Sylvie, et al. "A toolbox for conditional control of gene expression in apicomplexan parasites." Molecular microbiology vol. (2021). doi: https://doi.org/10.1111/mmi.14821
Briquet S, Gissot M, Silvie O. A toolbox for conditional control of gene expression in apicomplexan parasites. Mol Microbiol. 2021 Sep 26; doi: 10.1111/mmi.14821. Epub 2021 Sep 26. PMID: 34564906.
Copy Download .nbib Format: NLM
Elucidating Recombination Mediator Function Using Biophysical Tools.

Biology

Henry C, Henrikus SS.
PMID: 33916151
Biology (Basel). 2021 Apr 01;10(4). doi: 10.3390/biology10040288.

The recombination mediator proteins (RMPs) are ubiquitous and play a crucial role in genome stability. RMPs facilitate the loading of recombinases like RecA onto single-stranded (ss) DNA coated by single-strand binding proteins like SSB. Despite sharing a common function,...

Cite
Henry C, Henrikus SS. Elucidating Recombination Mediator Function Using Biophysical Tools. Biology (Basel). 2021;10(4)doi: 10.3390/biology10040288.
Henry, C., & Henrikus, S. S. (2021). Elucidating Recombination Mediator Function Using Biophysical Tools. Biology, 10(4), . https://doi.org/10.3390/biology10040288
Henry, Camille, and Henrikus, Sarah S. "Elucidating Recombination Mediator Function Using Biophysical Tools." Biology vol. 10,4 (2021). doi: https://doi.org/10.3390/biology10040288
Henry C, Henrikus SS. Elucidating Recombination Mediator Function Using Biophysical Tools. Biology (Basel). 2021 Apr 01;10(4). doi: 10.3390/biology10040288. PMID: 33916151; PMCID: PMC8066028.
Copy Download .nbib Format: NLM
Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination.

Nucleic acids research

Xu J, Zhao L, Peng S, Chu H, Liang R, Tian M, Connell PP, Li G, Chen C, Wang HW.
PMID: 34871438
Nucleic Acids Res. 2021 Dec 16;49(22):13135-13149. doi: 10.1093/nar/gkab1141.

Homologous recombination (HR) is a primary DNA double-strand breaks (DSBs) repair mechanism. The recombinases Rad51 and Dmc1 are highly conserved in the RecA family; Rad51 is mainly responsible for DNA repair in somatic cells during mitosis while Dmc1 only...

Cite
Xu J, Zhao L, Peng S, et al. Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination. Nucleic Acids Res. 2021;49(22):13135-13149doi: 10.1093/nar/gkab1141.
Xu, J., Zhao, L., Peng, S., Chu, H., Liang, R., Tian, M., Connell, P. P., Li, G., Chen, C., & Wang, H. W. (2021). Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination. Nucleic acids research, 49(22), 13135-13149. https://doi.org/10.1093/nar/gkab1141
Xu, Jingfei, et al. "Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination." Nucleic acids research vol. 49,22 (2021): 13135-13149. doi: https://doi.org/10.1093/nar/gkab1141
Xu J, Zhao L, Peng S, Chu H, Liang R, Tian M, Connell PP, Li G, Chen C, Wang HW. Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination. Nucleic Acids Res. 2021 Dec 16;49(22):13135-13149. doi: 10.1093/nar/gkab1141. PMID: 34871438.
Copy Download .nbib Format: NLM
Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration.

Cell reports

Cheung V, Chung P, Bjorni M, Shvareva VA, Lopez YC, Feinberg EH.
PMID: 34936877
Cell Rep. 2021 Dec 21;37(12):110131. doi: 10.1016/j.celrep.2021.110131.

Behavior arises from concerted activity throughout the brain. Consequently, a major focus of modern neuroscience is defining the physiology and behavioral roles of projection neurons linking different brain areas. Single-cell RNA sequencing has facilitated these efforts by revealing molecular...

Cite
Cheung V, Chung P, Bjorni M, et al. Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration. Cell Rep. 2021;37(12):110131doi: 10.1016/j.celrep.2021.110131.
Cheung, V., Chung, P., Bjorni, M., Shvareva, V. A., Lopez, Y. C., & Feinberg, E. H. (2021). Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration. Cell reports, 37(12), 110131. https://doi.org/10.1016/j.celrep.2021.110131
Cheung, Victoria, et al. "Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration." Cell reports vol. 37,12 (2021): 110131. doi: https://doi.org/10.1016/j.celrep.2021.110131
Cheung V, Chung P, Bjorni M, Shvareva VA, Lopez YC, Feinberg EH. Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration. Cell Rep. 2021 Dec 21;37(12):110131. doi: 10.1016/j.celrep.2021.110131. PMID: 34936877.
Copy Download .nbib Format: NLM
Expanding Diversity of .

Frontiers in microbiology

Steczkiewicz K, Prestel E, Bidnenko E, Szczepankowska AK.
PMID: 33959107
Front Microbiol. 2021 Apr 20;12:644622. doi: 10.3389/fmicb.2021.644622. eCollection 2021.

Bacteriophage-encoded single strand annealing proteins (SSAPs) are recombinases which can substitute the classical, bacterial RecA and manage the DNA metabolism at different steps of phage propagation. SSAPs have been shown to efficiently promote recombination between short and rather divergent...

Cite
Steczkiewicz K, Prestel E, Bidnenko E, et al. Expanding Diversity of . Front Microbiol. 2021;12:644622doi: 10.3389/fmicb.2021.644622.
Steczkiewicz, K., Prestel, E., Bidnenko, E., & Szczepankowska, A. K. (2021). Expanding Diversity of . Frontiers in microbiology, 12644622. https://doi.org/10.3389/fmicb.2021.644622
Steczkiewicz, Kamil, et al. "Expanding Diversity of ." Frontiers in microbiology vol. 12 (2021): 644622. doi: https://doi.org/10.3389/fmicb.2021.644622
Steczkiewicz K, Prestel E, Bidnenko E, Szczepankowska AK. Expanding Diversity of . Front Microbiol. 2021 Apr 20;12:644622. doi: 10.3389/fmicb.2021.644622. eCollection 2021. PMID: 33959107; PMCID: PMC8093625.
Copy Download .nbib Format: NLM
Helicase-like functions in phosphate loop containing beta-alpha polypeptides.

Proceedings of the National Academy of Sciences of the United States of America

Vyas P, Trofimyuk O, Longo LM, Deshmukh FK, Sharon M, Tawfik DS.
PMID: 33846247
Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). doi: 10.1073/pnas.2016131118.

The P-loop Walker A motif underlies hundreds of essential enzyme families that bind nucleotide triphosphates (NTPs) and mediate phosphoryl transfer (P-loop NTPases), including the earliest DNA/RNA helicases, translocases, and recombinases. What were the primordial precursors of these enzymes? Could...

Cite
Vyas P, Trofimyuk O, Longo LM, et al. Helicase-like functions in phosphate loop containing beta-alpha polypeptides. Proc Natl Acad Sci U S A. 2021;118(16)doi: 10.1073/pnas.2016131118.
Vyas, P., Trofimyuk, O., Longo, L. M., Deshmukh, F. K., Sharon, M., & Tawfik, D. S. (2021). Helicase-like functions in phosphate loop containing beta-alpha polypeptides. Proceedings of the National Academy of Sciences of the United States of America, 118(16), . https://doi.org/10.1073/pnas.2016131118
Vyas, Pratik, et al. "Helicase-like functions in phosphate loop containing beta-alpha polypeptides." Proceedings of the National Academy of Sciences of the United States of America vol. 118,16 (2021). doi: https://doi.org/10.1073/pnas.2016131118
Vyas P, Trofimyuk O, Longo LM, Deshmukh FK, Sharon M, Tawfik DS. Helicase-like functions in phosphate loop containing beta-alpha polypeptides. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). doi: 10.1073/pnas.2016131118. PMID: 33846247; PMCID: PMC8072362.
Copy Download .nbib Format: NLM
Robust Cre recombinase activity in the biotrophic smut fungus Ustilago maydis enables efficient conditional null mutants in planta.

Genetics

de la Torre A, Jurca M, Hoffmann K, Schmitz L, Heimel K, Kämper J, Pérez-Martín J.
PMID: 34849846
Genetics. 2021 Sep 17; doi: 10.1093/genetics/iyab152. Epub 2021 Sep 17.

Site-specific recombinases have been used in higher eukaryotes, especially in animals, for a broad range of applications, including chromosomal translocations, large deletions, site-specific integration, and tissue-specific as well as conditional knock-outs. The application of site-specific recombination has also been...

Cite
de la Torre A, Jurca M, Hoffmann K, et al. Robust Cre recombinase activity in the biotrophic smut fungus Ustilago maydis enables efficient conditional null mutants in planta. Genetics. 2021;doi: 10.1093/genetics/iyab152.
de la Torre, A., Jurca, M., Hoffmann, K., Schmitz, L., Heimel, K., Kämper, J., & Pérez-Martín, J. (2021). Robust Cre recombinase activity in the biotrophic smut fungus Ustilago maydis enables efficient conditional null mutants in planta. Genetics, . https://doi.org/10.1093/genetics/iyab152
de la Torre, Antonio, et al. "Robust Cre recombinase activity in the biotrophic smut fungus Ustilago maydis enables efficient conditional null mutants in planta." Genetics vol. (2021). doi: https://doi.org/10.1093/genetics/iyab152
de la Torre A, Jurca M, Hoffmann K, Schmitz L, Heimel K, Kämper J, Pérez-Martín J. Robust Cre recombinase activity in the biotrophic smut fungus Ustilago maydis enables efficient conditional null mutants in planta. Genetics. 2021 Sep 17; doi: 10.1093/genetics/iyab152. Epub 2021 Sep 17. PMID: 34849846; PMCID: PMC8733456.
Copy Download .nbib Format: NLM
Inner workings of RAG recombinase and its specialization for adaptive immunity.

Current opinion in structural biology

Chen X, Gellert M, Yang W.
PMID: 34245989
Curr Opin Struct Biol. 2021 Dec;71:79-86. doi: 10.1016/j.sbi.2021.05.014. Epub 2021 Jul 07.

RAG1/2 (RAG) is an RNH-type DNA recombinase specially evolved to initiate V(D)J gene rearrangement for generating the adaptive immune response in jawed vertebrates. After decades of frustration with little mechanistic understanding of RAG, the crystal structure of mouse RAG...

Cite
Chen X, Gellert M, Yang W. Inner workings of RAG recombinase and its specialization for adaptive immunity. Curr Opin Struct Biol. 2021;71:79-86doi: 10.1016/j.sbi.2021.05.014.
Chen, X., Gellert, M., & Yang, W. (2021). Inner workings of RAG recombinase and its specialization for adaptive immunity. Current opinion in structural biology, 7179-86. https://doi.org/10.1016/j.sbi.2021.05.014
Chen, Xuemin, et al. "Inner workings of RAG recombinase and its specialization for adaptive immunity." Current opinion in structural biology vol. 71 (2021): 79-86. doi: https://doi.org/10.1016/j.sbi.2021.05.014
Chen X, Gellert M, Yang W. Inner workings of RAG recombinase and its specialization for adaptive immunity. Curr Opin Struct Biol. 2021 Dec;71:79-86. doi: 10.1016/j.sbi.2021.05.014. Epub 2021 Jul 07. PMID: 34245989; PMCID: PMC8648925.
Copy Download .nbib Format: NLM
Harnessing orthogonal recombinases to decipher cell fate with enhanced precision.

Trends in cell biology

Weng W, Liu X, Lui KO, Zhou B.
PMID: 34657762
Trends Cell Biol. 2021 Oct 15; doi: 10.1016/j.tcb.2021.09.007. Epub 2021 Oct 15.

Precisely deciphering the cellular plasticity in vivo is essential in understanding many key biological processes. Site-specific recombinases are genetic tools used for in vivo lineage tracing and gene manipulation. Conventional Cre-loxP, Dre-rox, and Flp-frt technologies form the orthogonal recombination...

Cite
Weng W, Liu X, Lui KO, et al. Harnessing orthogonal recombinases to decipher cell fate with enhanced precision. Trends Cell Biol. 2021;doi: 10.1016/j.tcb.2021.09.007.
Weng, W., Liu, X., Lui, K. O., & Zhou, B. (2021). Harnessing orthogonal recombinases to decipher cell fate with enhanced precision. Trends in cell biology, . https://doi.org/10.1016/j.tcb.2021.09.007
Weng, Wendong, et al. "Harnessing orthogonal recombinases to decipher cell fate with enhanced precision." Trends in cell biology vol. (2021). doi: https://doi.org/10.1016/j.tcb.2021.09.007
Weng W, Liu X, Lui KO, Zhou B. Harnessing orthogonal recombinases to decipher cell fate with enhanced precision. Trends Cell Biol. 2021 Oct 15; doi: 10.1016/j.tcb.2021.09.007. Epub 2021 Oct 15. PMID: 34657762.
Copy Download .nbib Format: NLM
Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration.

Cell reports

Cheung V, Chung P, Bjorni M, Shvareva VA, Lopez YC, Feinberg EH.
PMID: 34936877
Cell Rep. 2021 Dec 21;37(12):110131. doi: 10.1016/j.celrep.2021.110131.

Behavior arises from concerted activity throughout the brain. Consequently, a major focus of modern neuroscience is defining the physiology and behavioral roles of projection neurons linking different brain areas. Single-cell RNA sequencing has facilitated these efforts by revealing molecular...

Cite
Cheung V, Chung P, Bjorni M, et al. Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration. Cell Rep. 2021;37(12):110131doi: 10.1016/j.celrep.2021.110131.
Cheung, V., Chung, P., Bjorni, M., Shvareva, V. A., Lopez, Y. C., & Feinberg, E. H. (2021). Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration. Cell reports, 37(12), 110131. https://doi.org/10.1016/j.celrep.2021.110131
Cheung, Victoria, et al. "Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration." Cell reports vol. 37,12 (2021): 110131. doi: https://doi.org/10.1016/j.celrep.2021.110131
Cheung V, Chung P, Bjorni M, Shvareva VA, Lopez YC, Feinberg EH. Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration. Cell Rep. 2021 Dec 21;37(12):110131. doi: 10.1016/j.celrep.2021.110131. PMID: 34936877; PMCID: PMC8719358.
Copy Download .nbib Format: NLM
Showing 25 to 36 of 80 entries