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Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression.

Psychoneuroendocrinology

Eliwa H, Brizard B, Le Guisquet AM, Hen R, Belzung C, Surget A.
PMID: 33302237
Psychoneuroendocrinology. 2021 Feb;124:105097. doi: 10.1016/j.psyneuen.2020.105097. Epub 2020 Dec 01.

Major depressive disorder is a common debilitating mental health problem that represents one of the leading causes of disability. Up to date, the therapeutic targets and approaches are still limited. Adult hippocampal neurogenesis (AHN) has been proposed as a...

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Eliwa H, Brizard B, Le Guisquet AM, et al. Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression. Psychoneuroendocrinology. 2020;124:105097doi: 10.1016/j.psyneuen.2020.105097.
Eliwa, H., Brizard, B., Le Guisquet, A. M., Hen, R., Belzung, C., & Surget, A. (2021). Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression. Psychoneuroendocrinology, 124105097. https://doi.org/10.1016/j.psyneuen.2020.105097
Eliwa, Hoda, et al. "Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression." Psychoneuroendocrinology vol. 124 (2021): 105097. doi: https://doi.org/10.1016/j.psyneuen.2020.105097
Eliwa H, Brizard B, Le Guisquet AM, Hen R, Belzung C, Surget A. Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression. Psychoneuroendocrinology. 2021 Feb;124:105097. doi: 10.1016/j.psyneuen.2020.105097. Epub 2020 Dec 01. PMID: 33302237; PMCID: PMC8715720.
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RAD51 supports DMC1 by inhibiting the SMC5/6 complex during meiosis.

The Plant cell

Chen H, He C, Wang C, Wang X, Ruan F, Yan J, Yin P, Wang Y, Yan S.
PMID: 34009315
Plant Cell. 2021 Aug 31;33(8):2869-2882. doi: 10.1093/plcell/koab136.

Meiosis is a fundamental process for sexual reproduction in most eukaryotes and the evolutionarily conserved recombinases RADiation sensitive51 (RAD51) and Disrupted Meiotic cDNA1 (DMC1) are essential for meiosis and thus fertility. The mitotic function of RAD51 is clear, but...

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Chen H, He C, Wang C, et al. RAD51 supports DMC1 by inhibiting the SMC5/6 complex during meiosis. Plant Cell. 2021;33(8):2869-2882doi: 10.1093/plcell/koab136.
Chen, H., He, C., Wang, C., Wang, X., Ruan, F., Yan, J., Yin, P., Wang, Y., & Yan, S. (2021). RAD51 supports DMC1 by inhibiting the SMC5/6 complex during meiosis. The Plant cell, 33(8), 2869-2882. https://doi.org/10.1093/plcell/koab136
Chen, Hanchen, et al. "RAD51 supports DMC1 by inhibiting the SMC5/6 complex during meiosis." The Plant cell vol. 33,8 (2021): 2869-2882. doi: https://doi.org/10.1093/plcell/koab136
Chen H, He C, Wang C, Wang X, Ruan F, Yan J, Yin P, Wang Y, Yan S. RAD51 supports DMC1 by inhibiting the SMC5/6 complex during meiosis. Plant Cell. 2021 Aug 31;33(8):2869-2882. doi: 10.1093/plcell/koab136. PMID: 34009315; PMCID: PMC8408460.
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Salmonella Genomic Island 1 requires a self-encoded small RNA for mobilization.

Molecular microbiology

Nagy I, Szabó M, Hegyi A, Kiss J.
PMID: 34784078
Mol Microbiol. 2021 Dec;116(6):1533-1551. doi: 10.1111/mmi.14846. Epub 2021 Nov 25.

The SGI1-family elements that are specifically mobilized by the IncA- and IncC-family plasmids are important vehicles of antibiotic resistance among enteric bacteria. Although SGI1 exploits many plasmid-derived conjugation and regulatory functions, the basic mobilization module of the island is...

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Nagy I, Szabó M, Hegyi A, et al. Salmonella Genomic Island 1 requires a self-encoded small RNA for mobilization. Mol Microbiol. 2021;116(6):1533-1551doi: 10.1111/mmi.14846.
Nagy, I., Szabó, M., Hegyi, A., & Kiss, J. (2021). Salmonella Genomic Island 1 requires a self-encoded small RNA for mobilization. Molecular microbiology, 116(6), 1533-1551. https://doi.org/10.1111/mmi.14846
Nagy, István, et al. "Salmonella Genomic Island 1 requires a self-encoded small RNA for mobilization." Molecular microbiology vol. 116,6 (2021): 1533-1551. doi: https://doi.org/10.1111/mmi.14846
Nagy I, Szabó M, Hegyi A, Kiss J. Salmonella Genomic Island 1 requires a self-encoded small RNA for mobilization. Mol Microbiol. 2021 Dec;116(6):1533-1551. doi: 10.1111/mmi.14846. Epub 2021 Nov 25. PMID: 34784078.
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Virus and Potential Host Microbes from Viral-Enriched Metagenomic Characterization in the High-Altitude Wetland, Salar de Huasco, Chile.

Microorganisms

Eissler Y, Dorador C, Kieft B, Molina V, Hengst M.
PMID: 32698305
Microorganisms. 2020 Jul 20;8(7). doi: 10.3390/microorganisms8071077.

Salar de Huasco is a wetland in the Andes mountains, located 3800 m above sea level at the Chilean Altiplano. Here we present a study aimed at characterizing the viral fraction and the microbial communities through metagenomic analysis. Two...

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Eissler Y, Dorador C, Kieft B, et al. Virus and Potential Host Microbes from Viral-Enriched Metagenomic Characterization in the High-Altitude Wetland, Salar de Huasco, Chile. Microorganisms. 2020;8(7)doi: 10.3390/microorganisms8071077.
Eissler, Y., Dorador, C., Kieft, B., Molina, V., & Hengst, M. (2020). Virus and Potential Host Microbes from Viral-Enriched Metagenomic Characterization in the High-Altitude Wetland, Salar de Huasco, Chile. Microorganisms, 8(7), . https://doi.org/10.3390/microorganisms8071077
Eissler, Yoanna, et al. "Virus and Potential Host Microbes from Viral-Enriched Metagenomic Characterization in the High-Altitude Wetland, Salar de Huasco, Chile." Microorganisms vol. 8,7 (2020). doi: https://doi.org/10.3390/microorganisms8071077
Eissler Y, Dorador C, Kieft B, Molina V, Hengst M. Virus and Potential Host Microbes from Viral-Enriched Metagenomic Characterization in the High-Altitude Wetland, Salar de Huasco, Chile. Microorganisms. 2020 Jul 20;8(7). doi: 10.3390/microorganisms8071077. PMID: 32698305; PMCID: PMC7409041.
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Sources of off-target expression from recombinase-dependent AAV vectors and mitigation with cross-over insensitive ATG-out vectors.

Proceedings of the National Academy of Sciences of the United States of America

Fischer KB, Collins HK, Callaway EM.
PMID: 31843925
Proc Natl Acad Sci U S A. 2019 Dec 16; doi: 10.1073/pnas.1915974116. Epub 2019 Dec 16.

In combination with transgenic mouse lines expressing Cre or Flp recombinases in defined cell types, recombinase-dependent adeno-associated viruses (AAVs) have become the tool of choice for localized cell-type-targeted gene expression. Unfortunately, applications of this technique when expressing highly sensitive...

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Fischer KB, Collins HK, Callaway EM. Sources of off-target expression from recombinase-dependent AAV vectors and mitigation with cross-over insensitive ATG-out vectors. Proc Natl Acad Sci U S A. 2019;doi: 10.1073/pnas.1915974116.
Fischer, K. B., Collins, H. K., & Callaway, E. M. (2019). Sources of off-target expression from recombinase-dependent AAV vectors and mitigation with cross-over insensitive ATG-out vectors. Proceedings of the National Academy of Sciences of the United States of America, . https://doi.org/10.1073/pnas.1915974116
Fischer, Kyle B, et al. "Sources of off-target expression from recombinase-dependent AAV vectors and mitigation with cross-over insensitive ATG-out vectors." Proceedings of the National Academy of Sciences of the United States of America vol. (2019). doi: https://doi.org/10.1073/pnas.1915974116
Fischer KB, Collins HK, Callaway EM. Sources of off-target expression from recombinase-dependent AAV vectors and mitigation with cross-over insensitive ATG-out vectors. Proc Natl Acad Sci U S A. 2019 Dec 16; doi: 10.1073/pnas.1915974116. Epub 2019 Dec 16. PMID: 31843925; PMCID: PMC6936690.
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Recombining DNA by protein swivels.

Structure (London, England : 1993)

Johnson RC, McLean MM.
PMID: 21645847
Structure. 2011 Jun 08;19(6):751-3. doi: 10.1016/j.str.2011.05.007.

Two new reports on serine recombinases, one of a crystal snapshot in an alternate rotational conformer poised for DNA cleavage (Keenholtz et al., 2011), and a second employing single-DNA molecule approaches (Bai et al., 2011), provide strong support for...

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Johnson RC, McLean MM. Recombining DNA by protein swivels. Structure. 2011;19(6):751-3doi: 10.1016/j.str.2011.05.007.
Johnson, R. C., & McLean, M. M. (2011). Recombining DNA by protein swivels. Structure (London, England : 1993), 19(6), 751-3. https://doi.org/10.1016/j.str.2011.05.007
Johnson, Reid C, and McLean, Meghan M. "Recombining DNA by protein swivels." Structure (London, England : 1993) vol. 19,6 (2011): 751-3. doi: https://doi.org/10.1016/j.str.2011.05.007
Johnson RC, McLean MM. Recombining DNA by protein swivels. Structure. 2011 Jun 08;19(6):751-3. doi: 10.1016/j.str.2011.05.007. PMID: 21645847.
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Thermodynamic Properties of Water Molecules at a Protein-Protein Interaction Surface.

Journal of chemical theory and computation

Huggins DJ, Marsh M, Payne MC.
PMID: 24554921
J Chem Theory Comput. 2011 Nov 08;7(11):3514-3522. doi: 10.1021/ct200465z. Epub 2011 Sep 20.

Protein-protein interactions (PPIs) have been identified as a vital regulator of cellular pathways and networks. However, the determinants that control binding affinity and specificity at protein surfaces are incompletely characterized and thus unable to be exploited for the purpose...

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Huggins DJ, Marsh M, Payne MC. Thermodynamic Properties of Water Molecules at a Protein-Protein Interaction Surface. J Chem Theory Comput. 2011;7(11):3514-3522doi: 10.1021/ct200465z.
Huggins, D. J., Marsh, M., & Payne, M. C. (2011). Thermodynamic Properties of Water Molecules at a Protein-Protein Interaction Surface. Journal of chemical theory and computation, 7(11), 3514-3522. https://doi.org/10.1021/ct200465z
Huggins, David J, et al. "Thermodynamic Properties of Water Molecules at a Protein-Protein Interaction Surface." Journal of chemical theory and computation vol. 7,11 (2011): 3514-3522. doi: https://doi.org/10.1021/ct200465z
Huggins DJ, Marsh M, Payne MC. Thermodynamic Properties of Water Molecules at a Protein-Protein Interaction Surface. J Chem Theory Comput. 2011 Nov 08;7(11):3514-3522. doi: 10.1021/ct200465z. Epub 2011 Sep 20. PMID: 24554921; PMCID: PMC3924879.
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Conditional mutagenesis of the genome using site-specific DNA recombination.

CSH protocols

Ohtsubo K, Marth JD.
PMID: 21357131
CSH Protoc. 2007 Jul 01;2007:pdb.top12. doi: 10.1101/pdb.top12.

INTRODUCTIONAltering the genome of intact cells and organisms by site-specific DNA recombination has become an important gene-transfer methodology. DNA modifications produced by gene transfer and homologous recombination are typically static once integrated among target cell chromosomes. In contrast, the...

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Ohtsubo K, Marth JD. Conditional mutagenesis of the genome using site-specific DNA recombination. CSH Protoc. 2007;2007:pdb.top12doi: 10.1101/pdb.top12.
Ohtsubo, K., & Marth, J. D. (2007). Conditional mutagenesis of the genome using site-specific DNA recombination. CSH protocols, 2007pdb.top12. https://doi.org/10.1101/pdb.top12
Ohtsubo, Kazuaki, and Marth, Jamey D. "Conditional mutagenesis of the genome using site-specific DNA recombination." CSH protocols vol. 2007 (2007): pdb.top12. doi: https://doi.org/10.1101/pdb.top12
Ohtsubo K, Marth JD. Conditional mutagenesis of the genome using site-specific DNA recombination. CSH Protoc. 2007 Jul 01;2007:pdb.top12. doi: 10.1101/pdb.top12. PMID: 21357131.
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Genetic methods to identify and manipulate newly born neurons in the adult brain.

Frontiers in neuroscience

Imayoshi I, Sakamoto M, Kageyama R.
PMID: 21562606
Front Neurosci. 2011 May 02;5:64. doi: 10.3389/fnins.2011.00064. eCollection 2011.

Although mammalian neurogenesis is mostly completed by the perinatal period, new neurons are continuously generated in the subventricular zone of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus. Since the discovery of adult neurogenesis, many...

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Imayoshi I, Sakamoto M, Kageyama R. Genetic methods to identify and manipulate newly born neurons in the adult brain. Front Neurosci. 2011;5:64doi: 10.3389/fnins.2011.00064.
Imayoshi, I., Sakamoto, M., & Kageyama, R. (2011). Genetic methods to identify and manipulate newly born neurons in the adult brain. Frontiers in neuroscience, 564. https://doi.org/10.3389/fnins.2011.00064
Imayoshi, Itaru, et al. "Genetic methods to identify and manipulate newly born neurons in the adult brain." Frontiers in neuroscience vol. 5 (2011): 64. doi: https://doi.org/10.3389/fnins.2011.00064
Imayoshi I, Sakamoto M, Kageyama R. Genetic methods to identify and manipulate newly born neurons in the adult brain. Front Neurosci. 2011 May 02;5:64. doi: 10.3389/fnins.2011.00064. eCollection 2011. PMID: 21562606; PMCID: PMC3087966.
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Filamentous phages of Ralstonia solanacearum: double-edged swords for pathogenic bacteria.

Frontiers in microbiology

Yamada T.
PMID: 24204365
Front Microbiol. 2013 Nov 04;4:325. doi: 10.3389/fmicb.2013.00325. eCollection 2013.

Some phages from genus Inovirus use host or bacteriophage-encoded site-specific integrases or recombinases establish a prophage state. During integration or excision, a superinfective form can be produced. The three states (free, prophage, and superinfective) of such phages exert different...

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Yamada T. Filamentous phages of Ralstonia solanacearum: double-edged swords for pathogenic bacteria. Front Microbiol. 2013;4:325doi: 10.3389/fmicb.2013.00325.
Yamada, T. (2013). Filamentous phages of Ralstonia solanacearum: double-edged swords for pathogenic bacteria. Frontiers in microbiology, 4325. https://doi.org/10.3389/fmicb.2013.00325
Yamada, Takashi. "Filamentous phages of Ralstonia solanacearum: double-edged swords for pathogenic bacteria." Frontiers in microbiology vol. 4 (2013): 325. doi: https://doi.org/10.3389/fmicb.2013.00325
Yamada T. Filamentous phages of Ralstonia solanacearum: double-edged swords for pathogenic bacteria. Front Microbiol. 2013 Nov 04;4:325. doi: 10.3389/fmicb.2013.00325. eCollection 2013. PMID: 24204365; PMCID: PMC3816273.
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Two different evolutionary lines of filamentous phages in Ralstonia solanacearum: their effects on bacterial virulence.

Frontiers in genetics

Askora A, Yamada T.
PMID: 26150828
Front Genet. 2015 Jun 18;6:217. doi: 10.3389/fgene.2015.00217. eCollection 2015.

The integration and excision of various filamentous phage genomes into and out of their host chromosomes occurs by site-specific recombination. The mechanisms proposed for these events include reactions mediated by phage-encoded recombinases and host recombination systems. Site-specific integration of...

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Askora A, Yamada T. Two different evolutionary lines of filamentous phages in Ralstonia solanacearum: their effects on bacterial virulence. Front Genet. 2015;6:217doi: 10.3389/fgene.2015.00217.
Askora, A., & Yamada, T. (2015). Two different evolutionary lines of filamentous phages in Ralstonia solanacearum: their effects on bacterial virulence. Frontiers in genetics, 6217. https://doi.org/10.3389/fgene.2015.00217
Askora, Ahmed, and Yamada, Takashi. "Two different evolutionary lines of filamentous phages in Ralstonia solanacearum: their effects on bacterial virulence." Frontiers in genetics vol. 6 (2015): 217. doi: https://doi.org/10.3389/fgene.2015.00217
Askora A, Yamada T. Two different evolutionary lines of filamentous phages in Ralstonia solanacearum: their effects on bacterial virulence. Front Genet. 2015 Jun 18;6:217. doi: 10.3389/fgene.2015.00217. eCollection 2015. PMID: 26150828; PMCID: PMC4471427.
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Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes.

Molecular systems biology

Smyshlyaev G, Bateman A, Barabas O.
PMID: 34018328
Mol Syst Biol. 2021 May;17(5):e9880. doi: 10.15252/msb.20209880.

Mobile genetic elements (MGEs) sequester and mobilize antibiotic resistance genes across bacterial genomes. Efficient and reliable identification of such elements is necessary to follow resistance spreading. However, automated tools for MGE identification are missing. Tyrosine recombinase (YR) proteins drive...

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Smyshlyaev G, Bateman A, Barabas O. Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes. Mol Syst Biol. 2021;17(5):e9880doi: 10.15252/msb.20209880.
Smyshlyaev, G., Bateman, A., & Barabas, O. (2021). Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes. Molecular systems biology, 17(5), e9880. https://doi.org/10.15252/msb.20209880
Smyshlyaev, Georgy, et al. "Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes." Molecular systems biology vol. 17,5 (2021): e9880. doi: https://doi.org/10.15252/msb.20209880
Smyshlyaev G, Bateman A, Barabas O. Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes. Mol Syst Biol. 2021 May;17(5):e9880. doi: 10.15252/msb.20209880. PMID: 34018328; PMCID: PMC8138268.
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Showing 13 to 24 of 80 entries