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Showing 25 to 36 of 282 entries
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Comparison of the therapeutic effectiveness of aprindine, procainamide and quinidine in chronic ventricular dysrhythmias.

British journal of clinical pharmacology

Van Durme JP, Bogaert MG, Rosseel MT.
PMID: 22454931
Br J Clin Pharmacol. 1974 Dec;1(6):461-6. doi: 10.1111/j.1365-2125.1974.tb01695.x.

1 A cross-over study with aprindine (100 mg daily after a loading dose of 200 mg), procainamide (4 × 1000 mg daily) and quinidine bisulphate (2 × 750 mg daily), all given orally, was performed in seventeen patients with...

Catalytic asymmetric desymmetrization of cyclic meso-1,3- and 1,4-diols by a phosphinite derivative of quinidine.

Organic letters

Mizuta S, Tsuzuki T, Fujimoto T, Yamamoto I.
PMID: 16092837
Org Lett. 2005 Aug 18;7(17):3633-5. doi: 10.1021/ol051129m.

Asymmetric monobenzoylation reactions of cyclic meso-1,3- and 1,4-diols were catalyzed by a phosphinite derivative of quinidine to afford the corresponding monobenzoylated diol with good yield and enantioselectivity. [reaction: see text]

Catalytic Regiodivergent Dearomatization Reaction of Nitrosocarbonyl Intermediates with β-Naphthols.

Organic letters

Mallik S, Bhajammanavar V, Mukherjee AP, Baidya M.
PMID: 30848924
Org Lett. 2019 Apr 05;21(7):2352-2355. doi: 10.1021/acs.orglett.9b00628. Epub 2019 Mar 08.

The divergent reactivity of nitrosocarbonyls in oxidative dearomatization of β-naphthols is reported. In the presence of quinidine catalyst, their reactions with α-unsubstituted β-naphthols proceeded through the N-center to furnish α-imino-β-naphthalenones in high yields. Upon exposure to α-substituted β-naphthols in...

Concurrent Quinidine and Phenobarbital in the Treatment of a Patient with 2 .

Current therapeutic research, clinical and experimental

Passey CC, Erramouspe J, Castellanos P, O'Donnell EC, Denton DM.
PMID: 31388363
Curr Ther Res Clin Exp. 2019 Feb 28;90:106-108. doi: 10.1016/j.curtheres.2019.02.002. eCollection 2019.

Epilepsy of infancy with migrating focal seizures is a devastating pediatric neurologic disorder that often results in treatment-resistant seizure activity and developmental delay. The condition has been associated with mutations in the

Spectroscopic Study of a .

ACS omega

Kumpulainen T, Qian J, Brouwer AM.
PMID: 29503974
ACS Omega. 2018 Feb 28;3(2):1871-1880. doi: 10.1021/acsomega.7b01713. Epub 2018 Feb 13.

A spectroscopic study of an organocatalytic Henry reaction between nitroalkanes and aldehydes catalyzed by a quinidine-derived

Quinidine thiourea-catalyzed enantioselective synthesis of β-nitrophosphonates: Beneficial effects of molecular sieves.

Tetrahedron

Abbaraju S, Bhanushali M, Zhao CG.
PMID: 21921970
Tetrahedron. 2011 Sep 30;67(39):7479-7484. doi: 10.1016/j.tet.2011.07.059.

An efficient method for enantioselective synthesis of β-nitrophosphonates via the Michael addition of diphenyl phosphite to nitroalkenes using the readily available quinidine thiourea organocatalyst has been developed. The desired β-nitrophosphonates were obtained in good ee values. Molecular sieves were...

The epidemiology and pathophysiology of pseudobulbar affect and its association with neurodegeneration.

Degenerative neurological and neuromuscular disease

King RR, Reiss JP.
PMID: 30890891
Degener Neurol Neuromuscul Dis. 2013 May 27;3:23-31. doi: 10.2147/DNND.S34160. eCollection 2013.

Pseudobulbar affect is a disorder resulting from neurologic damage manifesting as sudden, stereotyped affective outbursts that are not reflective of internal emotion. A literature review was completed to examine the current understanding of the epidemiology, characterization, diagnosis, pathophysiology, and...

Isoniazid-Induced Systemic Lupus Erythematosus: A Case Report.

Drug safety - case reports

Vaghela JH, Solanki Y, Lakhani K, Purohit B.
PMID: 31541371
Drug Saf Case Rep. 2019 Sep 20;6(1):7. doi: 10.1007/s40800-019-0102-y.

Systemic lupus erythematosus (SLE) can be induced by various medications, such as hydralazine, procainamide, isoniazid, methyldopa, chlorpromazine, quinidine, and minocycline. A patient was admitted complaining of fever with chills and rigor. After being diagnosed with tuberculous meningitis, the patient...

Catalytic Enantioselective Formal (4+2) Cycloaddition by Aldol-Aldol Annulation of Pyruvate Derivatives with Cyclohexane-1,3-Diones to Afford Functionalized Decalins.

Angewandte Chemie (International ed. in English)

Chouthaiwale PV, Aher RD, Tanaka F.
PMID: 30125444
Angew Chem Int Ed Engl. 2018 Oct 01;57(40):13298-13301. doi: 10.1002/anie.201808219. Epub 2018 Sep 07.

The decalin structure is found in bioactive molecules. We have developed catalytic enantioselective formal (4+2) cycloaddition reactions via aldol-aldol cascade reactions between pyruvate-derived diketoester derivatives and cyclohexane-1,3-dione derivatives that afford highly functionalized decalin derivatives. The reactions were performed using...

Corrigendum to "Does age affect response to quinidine in patients with KCNT1 mutations? Report of three new cases and review of the literature" [Seizure 55 (February) (2018) 1-3].

Seizure

Abdelnour E, Gallentine W, McDonald M, Sachdev M, Jiang YH, Mikati MA.
PMID: 31072785
Seizure. 2019 Jul;69:305. doi: 10.1016/j.seizure.2019.04.014. Epub 2019 May 06.

No abstract available.

Evaluation of silica from different vendors as the solid support of anion-exchange chiral stationary phases by means of preferential sorption and liquid chromatography.

Journal of separation science

Kohout M, Hovorka Š, Herciková J, Wilk M, Sysel P, Izák P, Bartůněk V, von Baeckmann C, Pícha J, Frühauf P.
PMID: 31625277
J Sep Sci. 2019 Dec;42(24):3653-3661. doi: 10.1002/jssc.201900731. Epub 2019 Nov 04.

Chromatographic performance of a chiral stationary phase is significantly influenced by the employed solid support. Properties of the most commonly used support, silica particles, such as size and size distribution, and pore size are of utmost importance for both...

Quinidine effective for the management of ventricular and atrial arrhythmias associated with Brugada syndrome.

HeartRhythm case reports

Halperin L, Mellor G, Talajic M, Krahn A, Tadros R, Laksman Z.
PMID: 30023269
HeartRhythm Case Rep. 2018 Apr 30;4(7):270-272. doi: 10.1016/j.hrcr.2018.01.008. eCollection 2018 Jul.

No abstract available.

Showing 25 to 36 of 282 entries