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Showing 13 to 24 of 282 entries
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mRNA expression and amino acid transport characteristics of cultured human brain microvascular endothelial cells (hBME).

Drug metabolism and pharmacokinetics

Umeki N, Fukasawa Y, Ohtsuki S, Hori S, Watanabe Y, Kohno Y, Terasaki T.
PMID: 15618688
Drug Metab Pharmacokinet. 2002;17(4):367-73. doi: 10.2133/dmpk.17.367.

An in vitro cell culture system for estimating the human blood-brain barrier (BBB) permeability of drugs is required for the development of drugs with effects on the central nervous system. In this study, cultured human brain microvascular endothelial cells...

Comparative analysis of in vitro and in vivo pharmacokinetic parameters related to individual variability of GTS-21 in canine.

Drug metabolism and pharmacokinetics

Azuma R, Komuro M, Kawaguchi Y, Okudaira K, Hayashi M, Kiwada H.
PMID: 15618655
Drug Metab Pharmacokinet. 2002;17(1):75-82. doi: 10.2133/dmpk.17.75.

To clarify the cause of the canine individual variability in plasma concentration after oral administration of GTS-21, we evaluated in vitro the metabolism to 4-OH-GTS-21 in liver microsomes of the same individuals from in vivo pharmacokinetic study. First, we...

Quinidine depresses the transmural electrical heterogeneity of transient outward potassium current of the right ventricular outflow tract free wall.

Journal of cardiovascular disease research

Zhou P, Yang X, Li C, Gao Y, Hu D.
PMID: 21188084
J Cardiovasc Dis Res. 2010 Jan;1(1):12-8. doi: 10.4103/0975-3583.59979.

BACKGROUND#ENTITYSTARTX02014;: Electrical heterogeneity of the right ventricular outflow tract (RVOT) is regarded as one of the main electrophysiological substrates for Brugada syndrome. Recently quinidine has shown efficacy in patients with Brugada syndrome due to its ability to inhibit potassium...

Internal medicine-epitomes of progress: digoxin, quinidine and sudden death.

The Western journal of medicine

Holford NH.
PMID: 18748676
West J Med. 1980 Sep;133(3):233-4.

No abstract available.

Auricular Flutter Restored to Normal Rhythm by Quinidine : With the Report of a Case.

Canadian Medical Association journal

Bourne CR.
PMID: 20316957
Can Med Assoc J. 1928 Aug;19(2):180-3.

No abstract available.

Electrical storms in Brugada syndrome successfully treated with isoproterenol infusion and quinidine orally.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Jongman JK, Jepkes-Bruin N, Ramdat Misier AR, Beukema WP, Delnoy PP, Oude Lutttikhuis H, Dambrink JH, Hoorntje JC, Elvan A.
PMID: 17612676
Neth Heart J. 2007;15(4):151-5. doi: 10.1007/BF03085972.

Brugada syndrome is an inherited cardiac disease and is associated with a peculiar pattern on the electrocardiogram and an increased risk of sudden death. Electrical storm is a malignant but rare phenomenon in symptomatic patients with Brugada syndrome. We...

Case of Auricular Fibrillation; Reversion to Normal Rhythm under Administration of Quinidine.

Proceedings of the Royal Society of Medicine

Parsons-Smith BT.
PMID: 19982797
Proc R Soc Med. 1923;16:50-2.

No abstract available.

DISCUSSION ON THE ACTION OF QUINIDINE IN CASES OF CARDIAC DISEASE.

Proceedings of the Royal Society of Medicine

Drury AN.
PMID: 19983479
Proc R Soc Med. 1923;16:30-2.

No abstract available.

DISCUSSION ON THE ACTION OF QUINIDINE IN CASES OF CARDIAC DISEASE.

Proceedings of the Royal Society of Medicine

Cotton TF.
PMID: 19983481
Proc R Soc Med. 1923;16:38-40.

No abstract available.

DISCUSSION ON THE ACTION OF QUINIDINE IN CASES OF CARDIAC DISEASE.

Proceedings of the Royal Society of Medicine

Weber FP.
PMID: 19983482
Proc R Soc Med. 1923;16:40-1.

No abstract available.

Exchange transfusion in a case of severe Plasmodium falciparum infection: a case report.

Canadian family physician Medecin de famille canadien

Brill-Edwards P, Keystone JS.
PMID: 21249094
Can Fam Physician. 1989 Oct;35:2129-73.

A 45-year-old Canadian man, who had recently returned from Cameroon, complained of fever lasting eight days. He had 40% parasitemia with Plasmodium falciparum. In spite of oral therapy with chloroquine, quinine, and tetracycline, the patient's condition deteriorated. Although his...

THE RESTORATION OF THE NORMAL CARDIAC MECHANISM IN CASES OF AURICULAR FIBRILLATION BY MEANS OF QUINIDINE SULPHATE.

British medical journal

Drury AN, Iliescu CC.
PMID: 20770429
Br Med J. 1921 Oct 01;2(3170):511-4. doi: 10.1136/bmj.2.3170.511.

No abstract available.

Showing 13 to 24 of 282 entries