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Showing 13 to 21 of 21 entries
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Effects of organic and inorganic salts on docosahexaenoic acid (DHA) production by a locally isolated strain of .

Preparative biochemistry & biotechnology

Chandrasekaran K, Dhanraj M, Chadha A.
PMID: 29869944
Prep Biochem Biotechnol. 2018;48(7):599-604. doi: 10.1080/10826068.2018.1476882. Epub 2018 Jun 05.

The traditional source for docosahexaenoic acid (DHA) i.e. fish oil is currently being replaced by microbial sources due to the unpleasant odor and the risk of chemical contamination of fish.

Enantioselective catalysis of the Henry reaction by a chiral macrocyclic ytterbium complex in aqueous media.

Organic & biomolecular chemistry

Pandya SU, Dickins RS, Parker D.
PMID: 18004465
Org Biomol Chem. 2007 Dec 07;5(23):3842-6. doi: 10.1039/b712470h. Epub 2007 Oct 29.

A chiral macrocyclic ytterbium cationic complex catalyses the nitro-aldol reaction between alpha-ketocarboxylates and nitromethane under ambient aqueous conditions, leading to the formation of for example, methyl-2-hydroxy-2-methyl-3-nitropropanoate in 96% yield and 59% enantiomeric purity. Monitoring of the paramagnetically shifted intermediate...

Lactate oxidation at the mitochondria: a lactate-malate-aspartate shuttle at work.

Frontiers in neuroscience

Kane DA.
PMID: 25505376
Front Neurosci. 2014 Nov 25;8:366. doi: 10.3389/fnins.2014.00366. eCollection 2014.

Lactate, the conjugate base of lactic acid occurring in aqueous biological fluids, has been derided as a "dead-end" waste product of anaerobic metabolism. Catalyzed by the near-equilibrium enzyme lactate dehydrogenase (LDH), the reduction of pyruvate to lactate is thought...

Ruthenium-Catalyzed Diastereoselective Synthesis of Fully Substituted Pyrrolidines from Anilines and Diazo Pyruvates.

Organic letters

Sajjad F, Krishna Reddy AG, Che J, Hu W, Xing D.
PMID: 32233439
Org Lett. 2020 Apr 17;22(8):3094-3098. doi: 10.1021/acs.orglett.0c00846. Epub 2020 Apr 01.

An unprecedented synthesis of polysubstituted pyrrolidines from anilines and diazo pyruvates by ruthenium catalysis under mild reaction conditions is reported. An enol intermediate derived from the N-H insertion of aniline toward the ruthenium carbene species as well as an...

Highly Enantioselective Nickel-Catalyzed Oxa-[3+3]-annulation of Phenols with Benzylidene Pyruvates for Chiral Chromans.

Organic letters

Ren H, Song XY, Wang SR, Wang L, Tang Y.
PMID: 29888607
Org Lett. 2018 Jul 06;20(13):3858-3861. doi: 10.1021/acs.orglett.8b01442. Epub 2018 Jun 11.

Nickel-catalyzed asymmetric annulation of oxygenated phenols and previously challenging 3-aminophenols with β,γ-unsaturated α-ketoesters is described, leading to rapid access to a variety of oxygenated and 7-aminated chromans in excellent yields with excellent diastereoselectivities and enantioselectivities under mild conditions. This...

Facile synthesis of 1,4-oxazines by ruthenium-catalyzed tandem N-H insertion/cyclization of α-arylamino ketones and diazo pyruvates.

Organic & biomolecular chemistry

Sajjad F, Chen Y, Tian X, Dong S, Gopi Krishna Reddy A, Hu W, Xing D.
PMID: 33538720
Org Biomol Chem. 2021 Mar 04;19(8):1769-1772. doi: 10.1039/d0ob01913e.

Herein, we report an efficient strategy for the rapid construction of 1,4-oxazines starting from simple α-amino ketones and diazo pyruvates under mild reaction conditions. This transformation is efficiently catalyzed by RuCl3 through a tandem N-H insertion/cyclization sequence via an...

Metabolic Reprogramming and Inflammatory Response Induced by D-Lactate in Bovine Fibroblast-Like Synoviocytes Depends on HIF-1 Activity.

Frontiers in veterinary science

Quiroga J, Alarcón P, Manosalva C, Teuber S, Taubert A, Hermosilla C, Hidalgo MA, Carretta MD, Burgos RA.
PMID: 33796579
Front Vet Sci. 2021 Mar 16;8:625347. doi: 10.3389/fvets.2021.625347. eCollection 2021.

Acute ruminal acidosis (ARA) occurs after an excessive intake of rapidly fermentable carbohydrates and is characterized by the overproduction of D-lactate in the rumen that reaches the bloodstream. Lameness presentation, one of the primary consequences of ARA in cattle,...

Removal of cell wall polysaccharide in pneumococcal capsular polysaccharides by selective degradation via deamination.

Carbohydrate polymers

Zou W, Li J, Vinogradov E, Cox A.
PMID: 31221321
Carbohydr Polym. 2019 Aug 15;218:199-207. doi: 10.1016/j.carbpol.2019.03.070. Epub 2019 Apr 20.

Pneumococcal cell wall polysaccharide (C-PS), a contaminant in pneumococcal capsular polysaccharide (Pn-PS) vaccines is degraded by mild deamination of the 4-amino-2-acetamido-2,4,6-tri-deoxy-galactose (AAT) in C-PS, which was carried out by addition of 5% aqueous sodium nitrite to a solution of...

Highly Selective Oxidation of Ethyl Lactate to Ethyl Pyruvate Catalyzed by Mesoporous Vanadia-Titania.

ACS catalysis

Zhang W, Innocenti G, Oulego P, Gitis V, Wu H, Ensing B, Cavani F, Rothenberg G, Shiju NR.
PMID: 29527403
ACS Catal. 2018 Mar 02;8(3):2365-2374. doi: 10.1021/acscatal.7b03843. Epub 2018 Jan 09.

The direct oxidative dehydrogenation of lactates with molecular oxygen is a "greener" alternative for producing pyruvates. Here we report a one-pot synthesis of mesoporous vanadia-titania (VTN), acting as highly efficient and recyclable catalysts for the conversion of ethyl lactate...

Showing 13 to 21 of 21 entries