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Showing 1381 to 1392 of 1392 entries
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Oxylipin patterns in human colon adenomas.

Prostaglandins, leukotrienes, and essential fatty acids

Schmöcker C, Gottschall H, Rund KM, Kutzner L, Nolte F, Ostermann AI, Hartmann D, Schebb NH, Weylandt KH.
PMID: 33812217
Prostaglandins Leukot Essent Fatty Acids. 2021 Apr;167:102269. doi: 10.1016/j.plefa.2021.102269. Epub 2021 Mar 23.

OBJECTIVE: Cyclooxygenase (COX)-derived prostaglandin EDESIGN: We quantified oxylipins in healthy colon tissue and colorectal adenoma tissue procured during routine colonoscopy examinations. Lipid metabolite profiles were analyzed by liquid chromatography-tandem mass spectrometry.RESULTS: Adenoma tissue showed a distinct prostaglandin profile as...

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Schmöcker C, Gottschall H, Rund KM, et al. Oxylipin patterns in human colon adenomas. Prostaglandins Leukot Essent Fatty Acids. 2021;167:102269doi: 10.1016/j.plefa.2021.102269.
Schmöcker, C., Gottschall, H., Rund, K. M., Kutzner, L., Nolte, F., Ostermann, A. I., Hartmann, D., Schebb, N. H., & Weylandt, K. H. (2021). Oxylipin patterns in human colon adenomas. Prostaglandins, leukotrienes, and essential fatty acids, 167102269. https://doi.org/10.1016/j.plefa.2021.102269
Schmöcker, Christoph, et al. "Oxylipin patterns in human colon adenomas." Prostaglandins, leukotrienes, and essential fatty acids vol. 167 (2021): 102269. doi: https://doi.org/10.1016/j.plefa.2021.102269
Schmöcker C, Gottschall H, Rund KM, Kutzner L, Nolte F, Ostermann AI, Hartmann D, Schebb NH, Weylandt KH. Oxylipin patterns in human colon adenomas. Prostaglandins Leukot Essent Fatty Acids. 2021 Apr;167:102269. doi: 10.1016/j.plefa.2021.102269. Epub 2021 Mar 23. PMID: 33812217.
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Platelet activating factor in the eye: Physiological roles, diseases and future perspectives.

Prostaglandins & other lipid mediators

Dalmaso B, da Silva-Junior IA, Fragel-Madeira L, Jancar S, Del Debbio CB.
PMID: 33358892
Prostaglandins Other Lipid Mediat. 2021 Apr;153:106522. doi: 10.1016/j.prostaglandins.2020.106522. Epub 2020 Dec 21.

Platelet Activating Factor (PAF) is a known phospholipid mediator of inflammation. Since its first description in 1972, it has emerged as a key regulator of vital cellular signaling functions, as proliferation, cell adhesion, and apoptosis. Evidence suggests that interactions...

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Dalmaso B, da Silva-Junior IA, Fragel-Madeira L, et al. Platelet activating factor in the eye: Physiological roles, diseases and future perspectives. Prostaglandins Other Lipid Mediat. 2020;153:106522doi: 10.1016/j.prostaglandins.2020.106522.
Dalmaso, B., da Silva-Junior, I. A., Fragel-Madeira, L., Jancar, S., & Del Debbio, C. B. (2021). Platelet activating factor in the eye: Physiological roles, diseases and future perspectives. Prostaglandins & other lipid mediators, 153106522. https://doi.org/10.1016/j.prostaglandins.2020.106522
Dalmaso, Barbara, et al. "Platelet activating factor in the eye: Physiological roles, diseases and future perspectives." Prostaglandins & other lipid mediators vol. 153 (2021): 106522. doi: https://doi.org/10.1016/j.prostaglandins.2020.106522
Dalmaso B, da Silva-Junior IA, Fragel-Madeira L, Jancar S, Del Debbio CB. Platelet activating factor in the eye: Physiological roles, diseases and future perspectives. Prostaglandins Other Lipid Mediat. 2021 Apr;153:106522. doi: 10.1016/j.prostaglandins.2020.106522. Epub 2020 Dec 21. PMID: 33358892.
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Prostaglandin signaling in ciliogenesis and development.

Journal of cellular physiology

Jin D, Zhong TP.
PMID: 34927727
J Cell Physiol. 2021 Dec 20; doi: 10.1002/jcp.30659. Epub 2021 Dec 20.

Prostaglandin (PG) signaling regulates a wide variety of physiological and pathological processes, including body temperature, cardiovascular homeostasis, reproduction, and inflammation. Recent studies have revealed that PGs play pivotal roles in embryo development, ciliogenesis, and organ formation. Prostaglandin E2 (PGE2)...

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Jin D, Zhong TP. Prostaglandin signaling in ciliogenesis and development. J Cell Physiol. 2021;doi: 10.1002/jcp.30659.
Jin, D., & Zhong, T. P. (2021). Prostaglandin signaling in ciliogenesis and development. Journal of cellular physiology, . https://doi.org/10.1002/jcp.30659
Jin, Daqing, and Zhong, Tao P. "Prostaglandin signaling in ciliogenesis and development." Journal of cellular physiology vol. (2021). doi: https://doi.org/10.1002/jcp.30659
Jin D, Zhong TP. Prostaglandin signaling in ciliogenesis and development. J Cell Physiol. 2021 Dec 20; doi: 10.1002/jcp.30659. Epub 2021 Dec 20. PMID: 34927727.
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Implications of Aspirin for Melanoma Treatment: A Short Perspective.

Journal of molecular genetics and medicine

Thyagarajan A, Sahu RP.
PMID: 34927173
J Mol Genet Med (Lond). 2017;1(1). Epub 2017 Aug 17.

Several human cancers including melanoma exhibit increased expression of inflammatory cyclooxygenases (COX) enzymes that catalyze the conversion of arachidonic acid to prostaglandins (PGs) implicated in tumor growth. As aspirin has been used in the treatment of various ailments including...

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Thyagarajan A, Sahu RP. Implications of Aspirin for Melanoma Treatment: A Short Perspective. J Mol Genet Med (Lond). 2017;1(1)
Thyagarajan, A., & Sahu, R. P. (2017). Implications of Aspirin for Melanoma Treatment: A Short Perspective. Journal of molecular genetics and medicine, 1(1), .
Thyagarajan, Anita, and Sahu, Ravi P. "Implications of Aspirin for Melanoma Treatment: A Short Perspective." Journal of molecular genetics and medicine vol. 1,1 (2017).
Thyagarajan A, Sahu RP. Implications of Aspirin for Melanoma Treatment: A Short Perspective. J Mol Genet Med (Lond). 2017;1(1). Epub 2017 Aug 17. PMID: 34927173; PMCID: PMC8681500.
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Translating n-3 polyunsaturated fatty acid status from whole blood to plasma and red blood cells during pregnancy: Translating n-3 status across blood fractions in pregnancy.

Prostaglandins, leukotrienes, and essential fatty acids

Simmonds LA, Yelland LN, Best KP, Liu G, Gibson RA, Makrides M.
PMID: 34864617
Prostaglandins Leukot Essent Fatty Acids. 2021 Nov 05;176:102367. doi: 10.1016/j.plefa.2021.102367. Epub 2021 Nov 05.

Women with low n-3 (omega-3) status in pregnancy can reduce their risk of early preterm birth (

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Simmonds LA, Yelland LN, Best KP, et al. Translating n-3 polyunsaturated fatty acid status from whole blood to plasma and red blood cells during pregnancy: Translating n-3 status across blood fractions in pregnancy. Prostaglandins Leukot Essent Fatty Acids. 2021;176:102367doi: 10.1016/j.plefa.2021.102367.
Simmonds, L. A., Yelland, L. N., Best, K. P., Liu, G., Gibson, R. A., & Makrides, M. (2021). Translating n-3 polyunsaturated fatty acid status from whole blood to plasma and red blood cells during pregnancy: Translating n-3 status across blood fractions in pregnancy. Prostaglandins, leukotrienes, and essential fatty acids, 176102367. https://doi.org/10.1016/j.plefa.2021.102367
Simmonds, Lucy A, et al. "Translating n-3 polyunsaturated fatty acid status from whole blood to plasma and red blood cells during pregnancy: Translating n-3 status across blood fractions in pregnancy." Prostaglandins, leukotrienes, and essential fatty acids vol. 176 (2021): 102367. doi: https://doi.org/10.1016/j.plefa.2021.102367
Simmonds LA, Yelland LN, Best KP, Liu G, Gibson RA, Makrides M. Translating n-3 polyunsaturated fatty acid status from whole blood to plasma and red blood cells during pregnancy: Translating n-3 status across blood fractions in pregnancy. Prostaglandins Leukot Essent Fatty Acids. 2021 Nov 05;176:102367. doi: 10.1016/j.plefa.2021.102367. Epub 2021 Nov 05. PMID: 34864617.
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Licofelone, a potent COX/5-LOX inhibitor and a novel option for treatment of neurological disorders.

Prostaglandins & other lipid mediators

Razavi SM, Khayatan D, Arab ZN, Momtaz S, Zare K, Jafari RM, Dehpour AR, Abdolghaffari AH.
PMID: 34517113
Prostaglandins Other Lipid Mediat. 2021 Dec;157:106587. doi: 10.1016/j.prostaglandins.2021.106587. Epub 2021 Sep 10.

Neurological disorders result in disability and morbidity. Neuroinflammation is a key factor involved in progression or resolution of a series of neurological disorders like Huntington disease (HD), Parkinson's disease (PD), Alzheimer's disease (AD), Spinal Cord Injury (SCI), and Seizure....

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Razavi SM, Khayatan D, Arab ZN, et al. Licofelone, a potent COX/5-LOX inhibitor and a novel option for treatment of neurological disorders. Prostaglandins Other Lipid Mediat. 2021;157:106587doi: 10.1016/j.prostaglandins.2021.106587.
Razavi, S. M., Khayatan, D., Arab, Z. N., Momtaz, S., Zare, K., Jafari, R. M., Dehpour, A. R., & Abdolghaffari, A. H. (2021). Licofelone, a potent COX/5-LOX inhibitor and a novel option for treatment of neurological disorders. Prostaglandins & other lipid mediators, 157106587. https://doi.org/10.1016/j.prostaglandins.2021.106587
Razavi, Seyed Mehrad, et al. "Licofelone, a potent COX/5-LOX inhibitor and a novel option for treatment of neurological disorders." Prostaglandins & other lipid mediators vol. 157 (2021): 106587. doi: https://doi.org/10.1016/j.prostaglandins.2021.106587
Razavi SM, Khayatan D, Arab ZN, Momtaz S, Zare K, Jafari RM, Dehpour AR, Abdolghaffari AH. Licofelone, a potent COX/5-LOX inhibitor and a novel option for treatment of neurological disorders. Prostaglandins Other Lipid Mediat. 2021 Dec;157:106587. doi: 10.1016/j.prostaglandins.2021.106587. Epub 2021 Sep 10. PMID: 34517113.
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The effect of a 6-month ketogenic medium-chain triglyceride supplement on plasma cardiometabolic and inflammatory markers in mild cognitive impairment.

Prostaglandins, leukotrienes, and essential fatty acids

Myette-Côté É, St-Pierre V, Beaulieu S, Castellano CA, Fortier M, Plourde M, Bocti C, Fulop T, Cunnane SC.
PMID: 33906081
Prostaglandins Leukot Essent Fatty Acids. 2021 Jun;169:102236. doi: 10.1016/j.plefa.2020.102236. Epub 2020 Dec 24.

INTRODUCTION: Mild cognitive impairment (MCI) is often accompanied by metabolic abnormalities and inflammation that might play a role in the development of cognitive impairment. The use of ketogenic medium-chain triglycerides (kMCT) to improve cognition in this population has shown...

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Myette-Côté É, St-Pierre V, Beaulieu S, et al. The effect of a 6-month ketogenic medium-chain triglyceride supplement on plasma cardiometabolic and inflammatory markers in mild cognitive impairment. Prostaglandins Leukot Essent Fatty Acids. 2020;169:102236doi: 10.1016/j.plefa.2020.102236.
Myette-Côté, �. �., St-Pierre, V., Beaulieu, S., Castellano, C. A., Fortier, M., Plourde, M., Bocti, C., Fulop, T., & Cunnane, S. C. (2021). The effect of a 6-month ketogenic medium-chain triglyceride supplement on plasma cardiometabolic and inflammatory markers in mild cognitive impairment. Prostaglandins, leukotrienes, and essential fatty acids, 169102236. https://doi.org/10.1016/j.plefa.2020.102236
Myette-Côté, Étienne, et al. "The effect of a 6-month ketogenic medium-chain triglyceride supplement on plasma cardiometabolic and inflammatory markers in mild cognitive impairment." Prostaglandins, leukotrienes, and essential fatty acids vol. 169 (2021): 102236. doi: https://doi.org/10.1016/j.plefa.2020.102236
Myette-Côté É, St-Pierre V, Beaulieu S, Castellano CA, Fortier M, Plourde M, Bocti C, Fulop T, Cunnane SC. The effect of a 6-month ketogenic medium-chain triglyceride supplement on plasma cardiometabolic and inflammatory markers in mild cognitive impairment. Prostaglandins Leukot Essent Fatty Acids. 2021 Jun;169:102236. doi: 10.1016/j.plefa.2020.102236. Epub 2020 Dec 24. PMID: 33906081.
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Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management.

Free radical biology & medicine

Jiang Q, Im S, Wagner JG, Hernandez ML, Peden DB.
PMID: 34896589
Free Radic Biol Med. 2021 Dec 09;178:347-359. doi: 10.1016/j.freeradbiomed.2021.12.012. Epub 2021 Dec 09.

γ-Tocopherol (γT) is a major form of vitamin E in the US diet and the second most abundant vitamin E in the blood and tissues, while α-tocopherol (αT) is the predominant vitamin E in tissues. During the last >25...

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Jiang Q, Im S, Wagner JG, et al. Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management. Free Radic Biol Med. 2021;178:347-359doi: 10.1016/j.freeradbiomed.2021.12.012.
Jiang, Q., Im, S., Wagner, J. G., Hernandez, M. L., & Peden, D. B. (2021). Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management. Free radical biology & medicine, 178347-359. https://doi.org/10.1016/j.freeradbiomed.2021.12.012
Jiang, Qing, et al. "Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management." Free radical biology & medicine vol. 178 (2021): 347-359. doi: https://doi.org/10.1016/j.freeradbiomed.2021.12.012
Jiang Q, Im S, Wagner JG, Hernandez ML, Peden DB. Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management. Free Radic Biol Med. 2021 Dec 09;178:347-359. doi: 10.1016/j.freeradbiomed.2021.12.012. Epub 2021 Dec 09. PMID: 34896589.
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Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels-A systematic review.

Prostaglandins, leukotrienes, and essential fatty acids

Mantzioris E, Muhlhausler BS, Villani A.
PMID: 34929617
Prostaglandins Leukot Essent Fatty Acids. 2022 Jan;176:102387. doi: 10.1016/j.plefa.2021.102387. Epub 2021 Dec 15.

INTRODUCTION: The Mediterranean Diet (MedDiet) is described as a plant-based dietary pattern with adherence associated with reductions in chronic disease risk and longevity. Although the nutrient profile is diverse and complex, the MedDiet is often described as a rich...

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Mantzioris E, Muhlhausler BS, Villani A. Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels-A systematic review. Prostaglandins Leukot Essent Fatty Acids. 2021;176:102387doi: 10.1016/j.plefa.2021.102387.
Mantzioris, E., Muhlhausler, B. S., & Villani, A. (2022). Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels-A systematic review. Prostaglandins, leukotrienes, and essential fatty acids, 176102387. https://doi.org/10.1016/j.plefa.2021.102387
Mantzioris, Evangeline, et al. "Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels-A systematic review." Prostaglandins, leukotrienes, and essential fatty acids vol. 176 (2022): 102387. doi: https://doi.org/10.1016/j.plefa.2021.102387
Mantzioris E, Muhlhausler BS, Villani A. Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels-A systematic review. Prostaglandins Leukot Essent Fatty Acids. 2022 Jan;176:102387. doi: 10.1016/j.plefa.2021.102387. Epub 2021 Dec 15. PMID: 34929617.
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Lung transplantation for pulmonary hypertension.

Journal of thoracic disease

Hwalek A, Rosenheck JP, Whitson BA.
PMID: 34992846
J Thorac Dis. 2021 Nov;13(11):6708-6716. doi: 10.21037/jtd-2021-20.

From its identification as a distinct disease entity, understanding and management of pulmonary hypertension has continuously evolved. Diagnostic and therapeutic interventions have greatly improved the prognostic implications of this devastating disease, previously rapidly and uniformly fatal to one chronically...

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Hwalek A, Rosenheck JP, Whitson BA. Lung transplantation for pulmonary hypertension. J Thorac Dis. 2021;13(11):6708-6716doi: 10.21037/jtd-2021-20.
Hwalek, A., Rosenheck, J. P., & Whitson, B. A. (2021). Lung transplantation for pulmonary hypertension. Journal of thoracic disease, 13(11), 6708-6716. https://doi.org/10.21037/jtd-2021-20
Hwalek, Ann, et al. "Lung transplantation for pulmonary hypertension." Journal of thoracic disease vol. 13,11 (2021): 6708-6716. doi: https://doi.org/10.21037/jtd-2021-20
Hwalek A, Rosenheck JP, Whitson BA. Lung transplantation for pulmonary hypertension. J Thorac Dis. 2021 Nov;13(11):6708-6716. doi: 10.21037/jtd-2021-20. PMID: 34992846; PMCID: PMC8662488.
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Targeted Lipidomic Analysis of Aqueous Humor Reveals Signaling Lipid-Mediated Pathways in Primary Open-Angle Glaucoma.

Biology

Azbukina NV, Chistyakov DV, Goriainov SV, Kotelin VI, Fedoseeva EV, Petrov SY, Sergeeva MG, Iomdina EN, Zernii EY.
PMID: 34356513
Biology (Basel). 2021 Jul 13;10(7). doi: 10.3390/biology10070658.

Primary open-angle glaucoma (POAG) is characterized by degeneration of retinal ganglion cells associated with an increase in intraocular pressure (IOP) due to hindered aqueous humor (AH) drainage through the trabecular meshwork and uveoscleral pathway. Polyunsaturated fatty acids and oxylipins...

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Azbukina NV, Chistyakov DV, Goriainov SV, et al. Targeted Lipidomic Analysis of Aqueous Humor Reveals Signaling Lipid-Mediated Pathways in Primary Open-Angle Glaucoma. Biology (Basel). 2021;10(7)doi: 10.3390/biology10070658.
Azbukina, N. V., Chistyakov, D. V., Goriainov, S. V., Kotelin, V. I., Fedoseeva, E. V., Petrov, S. Y., Sergeeva, M. G., Iomdina, E. N., & Zernii, E. Y. (2021). Targeted Lipidomic Analysis of Aqueous Humor Reveals Signaling Lipid-Mediated Pathways in Primary Open-Angle Glaucoma. Biology, 10(7), . https://doi.org/10.3390/biology10070658
Azbukina, Nadezhda V, et al. "Targeted Lipidomic Analysis of Aqueous Humor Reveals Signaling Lipid-Mediated Pathways in Primary Open-Angle Glaucoma." Biology vol. 10,7 (2021). doi: https://doi.org/10.3390/biology10070658
Azbukina NV, Chistyakov DV, Goriainov SV, Kotelin VI, Fedoseeva EV, Petrov SY, Sergeeva MG, Iomdina EN, Zernii EY. Targeted Lipidomic Analysis of Aqueous Humor Reveals Signaling Lipid-Mediated Pathways in Primary Open-Angle Glaucoma. Biology (Basel). 2021 Jul 13;10(7). doi: 10.3390/biology10070658. PMID: 34356513; PMCID: PMC8301454.
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Treatment of preadipocytes with fish oil, mixed oil, or soybean oil-based lipid emulsions have differential effects on the regulation of lipogenic and lipolytic genes in mature 3T3-L1 adipocytes.

Prostaglandins, leukotrienes, and essential fatty acids

Isesele P, Vaidya H, Gill R, Cheema SK.
PMID: 35032817
Prostaglandins Leukot Essent Fatty Acids. 2022 Jan 06;177:102396. doi: 10.1016/j.plefa.2022.102396. Epub 2022 Jan 06.

The key adipose tissue characteristics are established during early development, where lipids play an essential role. Lipid emulsions used in total parenteral nutrition have different omega-(n) 6 to n-3 fatty acid ratios. A lower n-6:n-3 fatty acid decreases lipid...

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Isesele P, Vaidya H, Gill R, et al. Treatment of preadipocytes with fish oil, mixed oil, or soybean oil-based lipid emulsions have differential effects on the regulation of lipogenic and lipolytic genes in mature 3T3-L1 adipocytes. Prostaglandins Leukot Essent Fatty Acids. 2022;177:102396doi: 10.1016/j.plefa.2022.102396.
Isesele, P., Vaidya, H., Gill, R., & Cheema, S. K. (2022). Treatment of preadipocytes with fish oil, mixed oil, or soybean oil-based lipid emulsions have differential effects on the regulation of lipogenic and lipolytic genes in mature 3T3-L1 adipocytes. Prostaglandins, leukotrienes, and essential fatty acids, 177102396. https://doi.org/10.1016/j.plefa.2022.102396
Isesele, Peter, et al. "Treatment of preadipocytes with fish oil, mixed oil, or soybean oil-based lipid emulsions have differential effects on the regulation of lipogenic and lipolytic genes in mature 3T3-L1 adipocytes." Prostaglandins, leukotrienes, and essential fatty acids vol. 177 (2022): 102396. doi: https://doi.org/10.1016/j.plefa.2022.102396
Isesele P, Vaidya H, Gill R, Cheema SK. Treatment of preadipocytes with fish oil, mixed oil, or soybean oil-based lipid emulsions have differential effects on the regulation of lipogenic and lipolytic genes in mature 3T3-L1 adipocytes. Prostaglandins Leukot Essent Fatty Acids. 2022 Jan 06;177:102396. doi: 10.1016/j.plefa.2022.102396. Epub 2022 Jan 06. PMID: 35032817.
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Showing 1381 to 1392 of 1392 entries