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Showing 25 to 36 of 61 entries
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Old stuff still trending: use of propafenone as a safety net until catheter ablation in a patient with documented pre-excited atrial fibrillation and Wolff-Parkinson-White syndrome - a classic case report.

European heart journal. Case reports

Karelas D, Papanikolaou J, Kossyvakis C, Platogiannis D.
PMID: 34909576
Eur Heart J Case Rep. 2021 Nov 30;5(12):ytab485. doi: 10.1093/ehjcr/ytab485. eCollection 2021 Dec.

BACKGROUND: Atrial fibrillation in WolffCASE SUMMARY: We report a case of a 43-year-old man with unremarkable cardiac history who presented due to sudden-onset feeling of palpitations and pre-syncope after strenuous lifting. Electrocardiography depicted fast pre-excited AF. The shortest pre-excited...

Illustrative and historic cases of phenoconversion.

American journal of translational research

Michaud V, Dow P, Turgeon J.
PMID: 35035679
Am J Transl Res. 2021 Dec 15;13(12):13328-13335. eCollection 2021.

Intersubject variability in drug response, whether related to efficacy or toxicity, is well recognized clinically. Over the years, drug selection from our pharmacologic armamentarium has moved from providers' preferred choices to more personalized treatments as clinicians' decisions are guided...

Propafenone and propranolol dual toxicity.

Journal of the American College of Emergency Physicians open

Farooq M, Qureshi F, Kamkoum W, Abuzeyad F.
PMID: 33145565
J Am Coll Emerg Physicians Open. 2020 Jun 11;1(5):1104-1107. doi: 10.1002/emp2.12126. eCollection 2020 Oct.

Propranolol is a highly lipid-soluble beta-receptor antagonist and propafenone is a potent class 1c anti-arrhythmic agent with strong Na-channel blockade effect. We describe a novel case of dual overdose of propafenone and propranolol resulting in hypotension, generalized seizures, and...

An integrated virtual screening and drug repurposing strategy for the discovery of new antimalarial drugs against Plasmodium falciparum phosphatidylinositol 3-kinase.

Journal of cellular biochemistry

Verma K, Lahariya AK, Dubey S, Verma AK, Das A, Schneider KA, Bharti PK.
PMID: 33998049
J Cell Biochem. 2021 Oct;122(10):1326-1336. doi: 10.1002/jcb.29954. Epub 2021 May 17.

The emergence and spread of drug resistance in Plasmodium falciparum, the parasite causing the most severe form of human malaria, is a major threat to malaria control and elimination programs around the globe. With P. falciparum having evolved widespread...

Electrophysiological effects and clinical utility of propafenone in children.

Cardiology in the young

Singh M, McKenzie K, Hudak ML, Gehi AK, Ferns SJ.
PMID: 34321127
Cardiol Young. 2021 Jul 29;1-5. doi: 10.1017/S1047951121002857. Epub 2021 Jul 29.

AIM: This retrospective case series study sought to describe the safety and clinical effectiveness of propafenone for the control of arrhythmias in children with and without CHD or cardiomyopathy.METHODS: We reviewed baseline characteristics and subsequent outcomes in a group...

Pharmacological and nonpharmacological prevention of atrial fibrillation after coronary artery bypass surgery.

The journal of Tehran Heart Center

Haghjoo M.
PMID: 23074627
J Tehran Heart Cent. 2012;7(1):2-9. Epub 2012 Feb 28.

Atrial fibrillation (AF) is the most common complication of coronary artery bypass graft surgery (CABG). The reported incidence of AF after CABG varies from 20% to 40%. Postoperative AF (POAF) is associated with increased incidence of hemodynamic instability, thromboembolic...

International cohort study on the effectiveness of dronedarone and other antiarrhythmic drugs for atrial fibrillation in real-world practice (EFFECT-AF).

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Khachatryan A, Merino JL, de Abajo FJ, Botto GL, Kirchhof P, Breithardt G, Stambler B, Abenhaim L, Grimaldi-Bensouda L.
PMID: 34792111
Europace. 2021 Nov 18; doi: 10.1093/europace/euab262. Epub 2021 Nov 18.

AIMS: To evaluate the effectiveness and safety of dronedarone compared with other commonly used antiarrhythmic drugs (AADs) for preventing atrial fibrillation (AF) recurrences.METHODS AND RESULTS: An international observational cohort study in Germany, Spain, Italy, and the USA enrolling patients...

Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone.

Heart rhythm

Holmes AP, Saxena P, Kabir SN, O'Shea C, Kuhlmann SM, Gupta S, Fobian D, Apicella C, O'Reilly M, Syeda F, Reyat JS, Smith GL, Workman AJ, Pavlovic D, Fabritz L, Kirchhof P.
PMID: 33737232
Heart Rhythm. 2021 Jul;18(7):1212-1220. doi: 10.1016/j.hrthm.2021.03.016. Epub 2021 Mar 16.

BACKGROUND: Although atrial fibrillation ablation is increasingly used for rhythm control therapy, antiarrhythmic drugs (AADs) are commonly used, either alone or in combination with ablation. The effectiveness of AADs is highly variable. Previous work from our group suggests that...

Antiarrhythmic Drugs.

Current treatment options in cardiovascular medicine

Singh SN, Patrick J, Patrick J.
PMID: 15324611
Curr Treat Options Cardiovasc Med. 2004 Oct;6(5):357-364. doi: 10.1007/s11936-004-0019-2.

Both supraventricular and ventricular arrhythmias are associated with increased mortality and morbidity. Numerous antiarrhythmics have been developed in an attempt to decrease the frequency of these arrhythmias, hoping to improve survival and improve quality of life. Antiarrhythmic agents are...

Arrhythmogenic right ventricular cardiomyopathy characterized by recurrent syncope during exercise: A case report.

World journal of clinical cases

Wu HY, Cao YW, Gao TJ, Fu JL, Liang L.
PMID: 34141771
World J Clin Cases. 2021 Jun 06;9(16):4095-4103. doi: 10.12998/wjcc.v9.i16.4095.

BACKGROUND: Arrhythmogenic right ventricular (RV) cardiomyopathy is a rare and currently underrecognized cardiomyopathy characterized by the replacement of RV myocardium by fibrofatty tissue. It may be asymptomatic or symptomatic (palpitations or syncope) and may induce sudden cardiac death, especially...

Old stuff still trending: use of propafenone as a safety net until catheter ablation in a patient with documented pre-excited atrial fibrillation and Wolff-Parkinson-White syndrome - a classic case report.

European heart journal. Case reports

Karelas D, Papanikolaou J, Kossyvakis C, Platogiannis D.
PMID: 34909576
Eur Heart J Case Rep. 2021 Nov 30;5(12):ytab485. doi: 10.1093/ehjcr/ytab485. eCollection 2021 Dec.

BACKGROUND: Atrial fibrillation in WolffCASE SUMMARY: We report a case of a 43-year-old man with unremarkable cardiac history who presented due to sudden-onset feeling of palpitations and pre-syncope after strenuous lifting. Electrocardiography depicted fast pre-excited AF. The shortest pre-excited...

Pharmacologic Cardioversion in Patients with Paroxysmal Atrial Fibrillation: A Network Meta-Analysis.

Cardiovascular drugs and therapy

Tsiachris D, Doundoulakis I, Pagkalidou E, Kordalis A, Deftereos S, Gatzoulis KA, Tsioufis K, Stefanadis C.
PMID: 33400054
Cardiovasc Drugs Ther. 2021 Apr;35(2):293-308. doi: 10.1007/s10557-020-07127-1. Epub 2021 Jan 05.

PURPOSE: We sought to indirectly compare and rank antiarrhythmic agents focusing exclusively on adults with paroxysmal atrial fibrillation in order to identify the most effective for pharmacologic cardioversion over different time settings (4 h as primary, and 12, 24...

Showing 25 to 36 of 61 entries